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Journal of Virology, ISSN 0022-538X, 08/2006, Volume 80, Issue 16, pp. 7995 - 8005
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
PROMYELOCYTIC LEUKEMIA PROTEIN | ND10 | DOT-ASSOCIATED PROTEINS | DISRUPTION | VIROLOGY | EARLY GENE-EXPRESSION | HOST-CELL | SP100 PROTEINS | REGULATORY PROTEIN | NUCLEAR DOMAIN 10 | IMMEDIATE-EARLY PROTEINS | RNA, Small Interfering - genetics | Autoantigens - metabolism | Nuclear Proteins - analysis | Tumor Suppressor Proteins - antagonists & inhibitors | Antigens, Nuclear - metabolism | Humans | Neoplasm Proteins - physiology | Neoplasm Proteins - antagonists & inhibitors | Immediate-Early Proteins - metabolism | Tumor Suppressor Proteins - genetics | Ubiquitin-Protein Ligases - analysis | Antigens, Nuclear - analysis | Immediate-Early Proteins - analysis | Neoplasm Proteins - genetics | Nuclear Proteins - genetics | Fibroblasts - chemistry | Fibroblasts - metabolism | Autoantigens - analysis | Genome, Viral | Gene Expression | Transcription Factors - physiology | Herpesvirus 1, Human - metabolism | Ubiquitin-Protein Ligases - metabolism | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | Transcription Factors - genetics | Adaptor Proteins, Signal Transducing - analysis | Tumor Suppressor Proteins - physiology | Immediate-Early Proteins - genetics | Gene Expression Regulation, Viral | Nuclear Proteins - antagonists & inhibitors | Herpesvirus 1, Human - genetics | Nuclear Proteins - physiology | Adaptor Proteins, Signal Transducing - metabolism | Ubiquitin-Protein Ligases - genetics | Promyelocytic Leukemia Protein | Virus-Cell Interactions
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 2004, Volume 32, Issue 4, pp. 1279 - 1288
Journal Article
Journal of Virology, ISSN 0022-538X, 08/2006, Volume 80, Issue 16, pp. 8006 - 8018
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
SIMPLEX-VIRUS TYPE-1 | VIROLOGY | EARLY GENE-EXPRESSION | COVALENT MODIFICATION | NUCLEAR DOMAIN-10 ND10 | FLUORESCENT PROTEIN | CREB BINDING-PROTEIN | RETROVIRAL RESTRICTION | TRANSACTIVATOR PROTEIN | ACUTE PROMYELOCYTIC LEUKEMIA | DNA-REPLICATION | Autoantigens - metabolism | Nuclear Proteins - analysis | Tumor Suppressor Proteins - antagonists & inhibitors | Antigens, Nuclear - metabolism | Virus Replication - genetics | Humans | Neoplasm Proteins - antagonists & inhibitors | Cytomegalovirus Infections - immunology | Cytomegalovirus Infections - metabolism | Neoplasm Proteins - metabolism | Viral Proteins - metabolism | Immediate-Early Proteins - metabolism | Cell Nucleus - metabolism | Tumor Suppressor Proteins - genetics | Cell Nucleus - virology | Trans-Activators - genetics | Antigens, Nuclear - analysis | Neoplasm Proteins - genetics | Nuclear Proteins - genetics | Cytomegalovirus - physiology | Fibroblasts - chemistry | Fibroblasts - metabolism | Autoantigens - analysis | Fibroblasts - virology | Tumor Suppressor Proteins - metabolism | Viral Proteins - genetics | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | Transcription Factors - genetics | Transcription Factors - metabolism | Adaptor Proteins, Signal Transducing - analysis | Immediate-Early Proteins - genetics | Gene Expression Regulation, Viral | Nuclear Proteins - antagonists & inhibitors | Trans-Activators - metabolism | Cell Nucleus - chemistry | Adaptor Proteins, Signal Transducing - metabolism | Promyelocytic Leukemia Protein | Virus-Cell Interactions
Journal Article
Annual Review of Biochemistry, ISSN 0066-4154, 2005, Volume 74, Issue 1, pp. 115 - 128
Hypoxia-inducible factor (HIF) is a master transcriptional regulator of hypoxia-inducible genes and consists of a labile a subunit (such as HIF1 alpha) and a... 
Von Hippel-Lindau | EGLN | FIH | Hydroxylation | Hypoxia-inducible factor (HIF) | HYPOXIA-INDUCIBLE FACTOR | hydroxylation | BIOCHEMISTRY & MOLECULAR BIOLOGY | HIPPEL-LINDAU PROTEIN | FACTOR 1-ALPHA | hypoxia-inducible factor (HIF) | MITOCHONDRIAL RESPIRATORY-CHAIN | von Hippel-Lindau | NITRIC-OXIDE | PROLYL-HYDROXYLASES | TUMOR-SUPPRESSOR PROTEIN | ENDOTHELIAL GROWTH-FACTOR | UBIQUITIN-PROTEASOME PATHWAY | PAS DOMAIN PROTEIN | Transcription Factors - chemistry | Humans | Multiprotein Complexes | Hypoxia-Inducible Factor 1, alpha Subunit | Procollagen-Proline Dioxygenase - metabolism | DNA-Binding Proteins - metabolism | Immediate-Early Proteins - metabolism | Tumor Suppressor Proteins - chemistry | Tumor Suppressor Proteins - genetics | Immediate-Early Proteins - chemistry | Nuclear Proteins - genetics | Tumor Suppressor Proteins - metabolism | Hypoxia-Inducible Factor 1 | Gene Expression Regulation | Ubiquitin-Protein Ligases - metabolism | Models, Molecular | Nuclear Proteins - metabolism | Hypoxia-Inducible Factor-Proline Dioxygenases | Dioxygenases | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Nuclear Proteins - chemistry | Ubiquitin-Protein Ligases - chemistry | DNA-Binding Proteins - chemistry | Proline - chemistry | Transcription Factors - metabolism | Animals | Immediate-Early Proteins - genetics | Procollagen-Proline Dioxygenase - genetics | Models, Biological | Von Hippel-Lindau Tumor Suppressor Protein | Procollagen-Proline Dioxygenase - chemistry | Ubiquitin-Protein Ligases - genetics | Proline | Research | Gene expression | Proteins | Oxygen | Biochemistry | Tumors
Journal Article
Biochemical Journal, ISSN 0264-6021, 05/2015, Volume 468, Issue 1, pp. 145 - 158
The immediate early gene product Arc (activity-regulated cytoskeleton-associated protein) is posited as a master regulator of long-term synaptic plasticity and... 
Presenilin-1 | Arc | Oligomerization | Protein purification | Synaptic plasticity | Protein stability | Biophysical characterization | IMMEDIATE-EARLY GENE | CYTOSKELETON-ASSOCIATED PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | protein purification | INTRINSICALLY UNSTRUCTURED PROTEINS | ARC/ARG3.1 | biophysical characterization | protein stability | CONSOLIDATION | oligomerization | DENDRITIC SPINE | DIFFERENTIAL SCANNING FLUOROMETRY | SEQUENCE ALIGNMENTS | synaptic plasticity | LONG-TERM POTENTIATION | presenilin-1 | Cytoskeletal Proteins - genetics | Humans | Protein Multimerization | Molecular Sequence Data | Genetic Variation | Nerve Tissue Proteins - chemistry | Neuronal Plasticity - physiology | Protein Structure, Quaternary | Cytoskeletal Proteins - physiology | Protein Stability | Protein Structure, Tertiary | Amino Acid Sequence | Cell Line | Nerve Tissue Proteins - physiology | Biophysical Phenomena | Protein Structure, Secondary | Models, Molecular | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Cytoskeletal Proteins - chemistry | Microscopy, Electron | Nerve Tissue Proteins - genetics | Sequence Homology, Amino Acid | Presenilin-1 - metabolism | Protein Binding | Amino Acid Substitution | WT, wild-type | Dh, hydrodynamic diameter | HCA, hydrophobic cluster analysis | TBST, Tris-buffered saline | F-actin, filamentous actin | Aβ, amyloid β-peptide | hArc, human Arc | RT, room temperature | DSC, differential scanning calorimetry | DSF, differential scanning fluorimetry | AMPA, α-amino-3-hydroxy-5-methyl isoxazole-4-propionic acid | LTD, long-term depression | RU, response units | LTP, long-term potentiation | TEV, tobacco etch virus | DLS, dynamic light scattering | 0.1% Tween 20 | Ni-NTA, Ni2+-nitrilotriacetate | Trx, thioredoxin | Arc, activity-regulated cytoskeleton-associated protein | MBP, maltose-binding protein | PS1, presenilin-1 | SPR, surface plasmon resonance | APP, amyloid precursor protein
Journal Article
Nature Communications, ISSN 2041-1723, 04/2016, Volume 7, Issue 1, p. 11022
Journal Article
Journal of Virology, ISSN 0022-538X, 03/2008, Volume 82, Issue 6, pp. 2661 - 2672
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
PROMOTER ACTIVITY | HISTONE DEACETYLATION | NUCLEAR-BODIES | LATENT INFECTION | VIROLOGY | EARLY GENE-EXPRESSION | REGULATORY PROTEIN | HUMAN FIBROBLASTS | NEURONAL CELLS | IMMEDIATE-EARLY GENE-1 | MEDIATED REPRESSION | Cell Line | Gene Expression | Transcription Factors - physiology | Immediate-Early Proteins - physiology | Humans | Neoplasm Proteins - physiology | Antigens, Nuclear - physiology | Viral Plaque Assay | DNA Primers | Ubiquitin-Protein Ligases - physiology | Autoantigens - physiology | Microscopy, Confocal | Tumor Suppressor Proteins - physiology | Herpesvirus 1, Human - physiology | Immediate-Early Proteins - genetics | Virus Replication | Base Sequence | Fluorescent Antibody Technique | Herpesvirus 1, Human - genetics | Nuclear Proteins - physiology | Mutation | Ubiquitin-Protein Ligases - genetics | Promyelocytic Leukemia Protein | Splenomegaly | Middle Aged | Male | Immediate-Early Proteins | Life Sciences | Leukemia, T-Cell | Antigens, Nuclear | Neoplasm Proteins | Receptors, Antigen, T-Cell, alpha-beta | Aged, 80 and over | Adult | Female | Clone Cells | Leukopenia | Autoantigens | Immunophenotyping | Herpesvirus 1, Human | Nuclear Proteins | Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor | Virology | Ubiquitin-Protein Ligases | Microbiology and Parasitology | Autoimmune Diseases | Receptors, Antigen, T-Cell, gamma-delta | Aged | Transcription Factors | Tumor Suppressor Proteins | Virus-Cell Interactions
Journal Article
Biochemical Journal, ISSN 0264-6021, 12/2004, Volume 384, Issue 3, pp. 477 - 488
We detected a protein in rabbit skeletal muscle extracts that was phosphorylated rapidly by SGK1 (serum- and glucocorticoid-induced kinase 1), but not by... 
Phosphorylation | Glycogen synthase kinase 3 (GSK3) | N-myc down-stream-regulated gene (NDRG) | p53 | Serum- and glucocorticoid-induced kinase 1 (SGK1) | glycogen synthase kinase 3 (GSK3) | EPITHELIAL NA+ CHANNEL | PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | GLYCOGEN-SYNTHASE KINASE-3 | TRANSCRIPTION | SERUM | P70 S6 KINASE | n-myc downstream-regulated gene (NDRG) | IN-VIVO | GENE FAMILY | serum- and glucocorticoid-induced kinase 1 (SGK1) | MAPKAP KINASE-1 | phosphorylation | Antibody Specificity | Multigene Family | Molecular Weight | Humans | Molecular Sequence Data | Substrate Specificity | Cell Cycle Proteins - classification | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Immediate-Early Proteins | Cell Cycle Proteins - immunology | Ribosomal Protein S6 Kinases, 90-kDa - metabolism | Antibodies - immunology | Cell Cycle Proteins - genetics | Proteins - classification | Nuclear Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Proto-Oncogene Proteins - metabolism | Amino Acid Sequence | Cell Line | Rabbits | Glycogen Synthase Kinase 3 - antagonists & inhibitors | Cell Cycle Proteins - metabolism | Enzyme Inhibitors - pharmacology | Protein-Serine-Threonine Kinases - genetics | Intracellular Signaling Peptides and Proteins | Nuclear Proteins - metabolism | Glycogen Synthase Kinase 3 - metabolism | Phosphoserine - metabolism | Proteins - immunology | Proteins - genetics | Proto-Oncogene Proteins c-akt | Animals | Proteins - metabolism | Ribosomal Protein S6 Kinases, 90-kDa - genetics | Mice | HeLa Cells | Tumor Suppressor Proteins | SGK1, serum- and glucocorticoid-induced kinase 1 | PDK1, 3-phosphoinositide-dependent kinase 1 | LDS, lithium dodecyl sulphate | RSK, p90 ribosomal S6 kinase | ENaC, epithelial sodium channel | FOXO3a, forkhead box O3a | ERK, extracellular-signal-regulated kinase | MALDI-TOF, matrix-assisted laser-desorption ionization–time-of-flight | PKB, protein kinase B | SAPK, stress-activated protein kinase | CDK, cyclin-dependent kinase | IGF-1, insulin-like growth factor-1 | DYRK1A, dual-specificity tyrosine phosphorylated and regulated kinase 1A | GST, glutathione S-transferase | PKC, protein kinase C | S6K, p70 ribosomal S6 kinase | GSK3, glycogen synthase kinase 3 | siRNA, small interfering RNA | KESTREL, kinase substrate tracking and elucidation | MAPK, mitogen-activated protein kinase | NDRG, n-myc downstream-regulated gene
Journal Article
Journal Article
Biochemical Journal, ISSN 0264-6021, 09/2015, Volume 470, Issue 3, pp. 303 - 317
Alzheimer's disease (AD) is a fatal neurodegenerative disease affecting 36 million people worldwide. Genetic and biochemical research indicate that the... 
Amyloid-βpeptide | Protein degradation | Alzheimer's disease | Amyloid precursor protein (APP) | FE65 | Serum- and glucocorticoid-induced kinase 1 (SGK1) | Alzheimer Disease - etiology | Amyloid Precursor Protein Secretases - genetics | Phosphorylation | Cricetulus | Amyloid beta-Protein Precursor - chemistry | Humans | Cercopithecus aethiops | Aspartic Acid Endopeptidases - genetics | Immediate-Early Proteins - metabolism | Nerve Tissue Proteins - chemistry | Proteolysis | Amyloid beta-Protein Precursor - metabolism | HEK293 Cells | Protein Interaction Domains and Motifs | Protein Stability | Nuclear Proteins - genetics | Binding Sites | Protein-Serine-Threonine Kinases - metabolism | CHO Cells | Recombinant Proteins - metabolism | Protein-Serine-Threonine Kinases - genetics | Models, Molecular | Recombinant Proteins - chemistry | Nuclear Proteins - metabolism | Recombinant Proteins - genetics | Nuclear Proteins - chemistry | Serine - chemistry | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Amyloid Precursor Protein Secretases - metabolism | Amyloid beta-Protein Precursor - genetics | Animals | Immediate-Early Proteins - genetics | Aspartic Acid Endopeptidases - metabolism | Alzheimer Disease - metabolism | Protein Binding | Protein Processing, Post-Translational | Proteasome Endopeptidase Complex - metabolism | COS Cells | serum- and glucocorticoid-induced kinase 1 (SGK1) | amyloid precursor protein (APP) | protein degradation | amyloid-β peptide
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2003, Volume 100, Issue 15, pp. 8892 - 8897
A hallmark of most neurodegenerative diseases, including those caused by polyglutamine expansion, is the formation of ubiquitin (Ub)-positive protein... 
Proteins | Biological Sciences | Nervous system diseases | Motifs | Neurodegenerative diseases | HEK293 cells | Neurons | Progressive myoclonic epilepsies | Spinocerebellar ataxia | Cell aggregates | Amino acids | CUE DOMAIN | LOCALIZATION | RECRUITMENT | EXPANDED POLYGLUTAMINE | MULTIUBIQUITIN-CHAIN-BINDING | MULTIDISCIPLINARY SCIENCES | MACHADO-JOSEPH-DISEASE | SPINOCEREBELLAR ATAXIA TYPE-3 | NUCLEAR INCLUSIONS | PROTEASOME | INTRANUCLEAR INCLUSIONS | Ataxin-3 | Neurodegenerative Diseases - etiology | Sequestosome-1 Protein | Humans | Repressor Proteins | Ubiquitin - metabolism | Molecular Sequence Data | Multienzyme Complexes - metabolism | Proteasome Endopeptidase Complex | Recombinant Fusion Proteins - metabolism | Immediate-Early Proteins - metabolism | Nerve Tissue Proteins - chemistry | Cysteine Endopeptidases - metabolism | Peptides - metabolism | Transfection | Immediate-Early Proteins - chemistry | Carrier Proteins - chemistry | Amino Acid Sequence | Cell Line | Peptides - chemistry | Ubiquitin - chemistry | Neurodegenerative Diseases - genetics | Multienzyme Complexes - genetics | Binding Sites - genetics | Neurodegenerative Diseases - metabolism | Recombinant Fusion Proteins - chemistry | Nerve Tissue Proteins - genetics | Amino Acid Motifs | Nuclear Proteins | Nerve Tissue Proteins - metabolism | Proteins - genetics | Sequence Homology, Amino Acid | Carrier Proteins - genetics | Adaptor Proteins, Signal Transducing | Animals | Carrier Proteins - metabolism | Immediate-Early Proteins - genetics | Proteins - metabolism | Cysteine Endopeptidases - genetics | Recombinant Fusion Proteins - genetics | Mutation | Proteins - chemistry | In Vitro Techniques | Nervous system | Degeneration
Journal Article