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PLoS ONE, ISSN 1932-6203, 09/2016, Volume 11, Issue 9, pp. e0163521 - e0163521
Metastasis is the most common cause of mortality in breast cancer patients worldwide. To identify improved mouse models for breast cancer growth and... 
NATURAL-KILLER-CELLS | ENGRAFTMENT | MOUSE STRAINS | LUNG METASTASES | SCID MICE | MULTIDISCIPLINARY SCIENCES | GENOMIC ANALYSIS | NULL MICE | HUMAN-TUMORS | T-CELLS | IMMUNODEFICIENT | Liver | Estrogen | Breast cancer | Models | Metastasis | Comparative analysis | Health aspects | Brain | Animal models | Lymphatic system | Estrogens | Kinases | Gene expression | Patients | Lymph nodes | Metastases | Medicine | Pathology | Hypotheses | Lungs | Breast | Bones | Mice | Cancer | Tumors
Journal Article
Immunity, ISSN 1074-7613, 2008, Volume 29, Issue 6, pp. 947 - 957
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2017, Volume 114, Issue 41, pp. 10954 - 10959
There is an urgent and unmet need for humanized in vivo models of type 1 diabetes to study immunopathogenesis and immunotherapy, and in particular... 
Humanized mice | Type 1 diabetes | Insulin | IMMUNODEFICIENT MICE | type 1 diabetes | insulin | MULTIDISCIPLINARY SCIENCES | humanized mice | RECEPTOR | PEPTIDE | HUMAN PERIPHERAL-BLOOD | MOUSE MODEL | HUMAN IMMUNE-SYSTEM | RECONSTITUTION | T-CELLS | TRANSGENIC MICE | Autoimmunity | Humans | Insulin - immunology | Cells, Cultured | Diabetes Mellitus, Experimental - genetics | Diabetes Mellitus, Type 1 - pathology | Diabetes Mellitus, Type 1 - genetics | Mice, Transgenic | Mice, SCID | HLA-DQ Antigens - immunology | Insulin-Secreting Cells - immunology | CD4-Positive T-Lymphocytes - immunology | Diabetes Mellitus, Experimental - immunology | Animals | Autoantigens - immunology | Peptide Fragments - immunology | Diabetes Mellitus, Experimental - pathology | Mice, Inbred NOD | Mice | Diabetes Mellitus, Type 1 - immunology | Development and progression | Models | Animal models in research | Methods | Animal models | Pathogenesis | Transplantation | Lymphocytes T | Thymus | T-cell receptor | Hyperglycemia | Immunology | Lymphocytes | Rodents | Immunotherapy | Xenografts | Immunopathogenesis | Pancreas | Immune system | CD34 antigen | Autografts | Pathogens | Immunization | Cell survival | Diabetes mellitus | Fetuses | Immunodeficiency | Transgenic mice | Autoantigens | CD3 antigen | Cells | CD4 antigen | Pathogenicity | Beta cells | In vivo methods and tests | Infiltration | Histocompatibility antigen HLA | Diabetes | Islets of Langerhans | Index Medicus | Biological Sciences
Journal Article
Journal Article
Journal Article
Journal Article
INTERNATIONAL IMMUNOLOGY, ISSN 0953-8178, 07/2009, Volume 21, Issue 7, pp. 843 - 858
'Humanized mice' are anticipated to be a valuable tool for studying the human immune system, but the reconstituted human immune cells have not yet been well... 
IMMUNODEFICIENT MICE | RECEPTOR-GAMMA CHAIN | thymus | LYMPHOID DEVELOPMENT | SCID MICE | humanized mice | IMMUNOLOGY | adaptive immunity | IMMUNE-SYSTEM | IN-VIVO | MOUSE MODEL | HOST-DISEASE | DIFFERENTIATION | NOG mice | BLOOD CD34(+) CELLS
Journal Article