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humans (496) 496
imp dehydrogenase - antagonists & inhibitors (350) 350
index medicus (301) 301
animals (261) 261
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imp dehydrogenase (249) 249
biochemistry & molecular biology (210) 210
mycophenolic acid - pharmacology (179) 179
enzyme inhibitors - pharmacology (177) 177
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inosine monophosphate dehydrogenase (159) 159
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mycophenolate mofetil (71) 71
tiazofurin (71) 71
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structure-activity relationship (70) 70
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protein binding (37) 37
cell division - drug effects (36) 36
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apoptosis - drug effects (35) 35
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human normal lymphocytes (35) 35
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Journal Article
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2012, Volume 7, Issue 12, p. e51096
Journal Article
The Journal of Clinical Pharmacology, ISSN 0091-2700, 03/2011, Volume 51, Issue 3, pp. 309 - 320
Monitoring inosine monophosphate dehydrogenase (IMPDH) activity as a biomarker of mycophenolic acid (MPA)–induced immunosuppression may serve as a novel... 
pharmacokinetics | pediatric patient | inosine monophosphate dehydrogenase (IMPDH) | pharmacodynamics | mycophenolic acid | kidney transplantation | RENAL-ALLOGRAFT RECIPIENTS | HUMAN PLASMA | MONONUCLEAR-CELLS | CHILDREN | POLYMORPHISMS | NONRADIOACTIVE DETERMINATION | PHARMACOLOGY & PHARMACY | OUTCOMES | EXPOSURE | MOFETIL | IMP Dehydrogenase - blood | Enzyme Inhibitors - blood | Humans | Immunosuppressive Agents - pharmacokinetics | Immunosuppressive Agents - therapeutic use | Child, Preschool | Male | Metabolic Clearance Rate | Glucuronides - blood | Immunosuppressive Agents - blood | Enzyme Inhibitors - pharmacokinetics | Biotransformation | Female | Mycophenolic Acid - blood | Child | Enzyme Inhibitors - adverse effects | Leukocytes, Mononuclear - drug effects | Mycophenolic Acid - pharmacokinetics | Biomarkers - blood | Enzyme Inhibitors - therapeutic use | Mycophenolic Acid - adverse effects | Prodrugs - adverse effects | Mycophenolic Acid - analogs & derivatives | Mycophenolic Acid - therapeutic use | IMP Dehydrogenase - antagonists & inhibitors | Prodrugs - pharmacokinetics | Models, Biological | Adolescent | Immunosuppressive Agents - adverse effects | Leukocytes, Mononuclear - enzymology | Prodrugs - therapeutic use | Kidney Transplantation - adverse effects | Preoperative Period | Kidneys | Dosage and administration | Pharmacology | Transplantation | Mycophenolate mofetil | Research | Health aspects
Journal Article
CLINICAL BIOCHEMISTRY, ISSN 0009-9120, 10/2001, Volume 34, Issue 7, pp. 543 - 549
Background: The immunosuppressive activity of mycophenolate mofetil (MMF) is based on the reversible inhibition of inosine 5'-monophosphate dehydrogenase... 
mycophenolic acid | drug monitoring | IMP dehydrogenase | INDUCTION | PHARMACODYNAMIC ASSESSMENT | high pressure liquid chromatography | mononuclear leukocytes | kidney | WHOLE-BLOOD | INHIBITION | transplantation | MEDICAL LABORATORY TECHNOLOGY | ACID-INDUCED IMMUNOSUPPRESSION | EXPRESSION | renal dialysis | MYCOPHENOLIC-ACID | MOFETIL | LYMPHOCYTES
Journal Article
Journal Article
Journal Article