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BBA - Proteins and Proteomics, ISSN 1570-9639, 01/2012, Volume 1824, Issue 1, pp. 44 - 50
Autophagy is a process involved in the proteolytic degradation of cellular macromolecules in lysosomes, which requires the activity of proteases, enzymes that... 
Cathepsins | Calpains | Caspases | Proteases | Autophagy | IMPAIRED AUTOPHAGY | CHAPERONE-MEDIATED AUTOPHAGY | BIOCHEMISTRY & MOLECULAR BIOLOGY | LYSOSOMAL STORAGE | RECEPTOR | CLEAVAGE | PROGRAMMED CELL-DEATH | PEPTIDE SEQUENCES | BIOPHYSICS | CATHEPSIN-L | DEGRADATION | CYTOSOLIC PROTEINS | Enzymes | Cysteine | Peptides | Proteolysis | Superoxide | Cystine
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 12/2016, Volume 20, Issue 12, pp. 2349 - 2361
Journal Article
Autophagy, ISSN 1554-8627, 04/2015, Volume 11, Issue 4, pp. 585 - 594
Genetic variations in the autophagic pathway influence genetic predispositions to Crohn disease. Autophagy, the major lysosomal pathway for degrading and... 
XBP1, X-box binding protein 1 | MTOR, mechanistic target of rapamycin | autophagy | DCs, dendritic cells | UC, ulcerative colitis | bacterial clearance | NFKB, nuclear factor of kappa light polypeptide gene enhancer in B-cells | SNP, single-nucleotide polymorphism | NOD2 | T300A, threonine-to-alanine substitution at amino acid position 300 | MDP, muramyl dipeptide | ULK1, unc-51 like autophagy-activating kinase 1 | endoplasmic reticulum stress | RIPK2, receptor-interacting serine-threonine kinase 2 | Crohn disease | ATG16L1 | ATG16L1, autophagy-related 16-like 1 (S. cerevisiae) | IBD, inflammatory bowel disease | TNF/TNF-α, tumor necrosis factor | NOD2, nucleotide-binding oligomerization domain containing 2 | ER, endoplasmic reticulum | GWAS, genome-wide association studies | BCL2, B-cell CLL/lymphoma 2 | Autophagy | Bacterial clearance | Endoplasmic reticulum stress | IMPAIRED AUTOPHAGY | REGULATES AUTOPHAGY | SELECTIVE AUTOPHAGY | INTESTINAL EPITHELIAL-CELLS | CELL BIOLOGY | AUTOPHAGY GENE ATG16L1 | INFLAMMATORY-BOWEL-DISEASE | RECYCLING ENDOSOMES | PROTEIN LIPIDATION | PANETH CELLS | GENOME-WIDE ASSOCIATION | Carrier Proteins - genetics | Crohn Disease - genetics | Autophagy-Related Proteins | Genetic Predisposition to Disease - genetics | Animals | Humans | Crohn Disease - metabolism | Polymorphism, Single Nucleotide - genetics | Autophagy - physiology | Autophagy - genetics | Endoplasmic Reticulum Stress - genetics
Journal Article
Journal Article
Gastroenterology, ISSN 0016-5085, 10/2018, Volume 155, Issue 4, pp. 1273 - 1274
Journal Article
Journal Article
BBA - Molecular Basis of Disease, ISSN 0925-4439, 01/2019, Volume 1865, Issue 1, pp. 48 - 55
The prevalence of cardiometabolic disease has reached an exponential rate of rise over the last decades owing to high fat/high caloric diet intake and satiety... 
Cardiometabolic diseases | Endocrine disorders | Inherited myopathies | Autophagy | IMPAIRED AUTOPHAGY | DANON-DISEASE | ENHANCED AUTOPHAGY | BIOCHEMISTRY & MOLECULAR BIOLOGY | MITOCHONDRIAL AUTOPHAGY | HEART-FAILURE | LYSOSOMAL STORAGE | BIOPHYSICS | INDUCED CARDIAC-HYPERTROPHY | ENZYME REPLACEMENT THERAPY | HEPATIC STEATOSIS |