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by Dickinson, Mary E and Flenniken, Ann M and Ji, Xiao and Teboul, Lydia and Wong, Michael D and White, Jacqueline K and Meehan, Terrence F and Weninger, Wolfgang J and Westerberg, Henrik and Adissu, Hibret and Baker, Candice N and Bower, Lynette and Brown, James M and Brianna Caddle, L and Chiani, Francesco and Clary, Dave and Cleak, James and Daly, Mark J and Denegre, James M and Doe, Brendan and Dolan, Mary E and Edie, Sarah M and Fuchs, Helmut and Gailus-Durner, Valerie and Galli, Antonella and Gambadoro, Alessia and Gallegos, Juan and Guo, Shiying and Horner, Neil R and Hsu, Chih-wei and Johnson, Sara J and Kalaga, Sowmya and Keith, Lance C and Lanoue, Louise and Lawson, Thomas N and Lek, Monkol and Mark, Manuel and Marschall, Susan and Mason, Jeremy and McElwee, Melissa L and Newbigging, Susan and Nutter, Lauryl M.J and Peterson, Kevin A and Ramirez-Solis, Ramiro and Rowland, Douglas J and Ryder, Edward and Samocha, Kaitlin E and Seavitt, John R and Selloum, Mohammed and Szoke-Kovacs, Zsombor and Tamura, Masaru and Trainor, Amanda G and Tudose, Ilinca and Wakana, Shigeharu and Warren, Jonathan and Wendling, Olivia and West, David B and Wong, Leeyean and Yoshiki, Atsushi and MacArthur, Daniel G and Tocchini-Valentini, Glauco P and Gao, Xiang and Flicek, Paul and Bradley, Allan and Skarnes, William C and Justice, Monica J and Parkinson, Helen E and Moore, Mark and Wells, Sara and Braun, Robert E and Svenson, Karen L and Hrabe de Angelis, Martin and Herault, Yann and Mohun, Tim and Mallon, Ann-Marie and Mark Henkelman, R and Brown, Steve D.M and Adams, David J and Kent Lloyd, K.C and McKerlie, Colin and Beaudet, Arthur L and Bucan, Maja and Murray, Stephen A and McKay, Matthew and Urban, Barbara and Lund, Caroline and Froeter, Erin and LaCasse, Taylor and Mehalow, Adrienne and Gordon, Emily and Donahue, Leah Rae and Taft, Robert and Kutney, Peter and Dion, Stephanie and Goodwin, Leslie and Kales, Susan and Urban, Rachel and Palmer, Kristina and Pertuy, Fabien and Bitz, Deborah and ... and Int Mouse Phenotyping Consortium and The International Mouse Phenotyping Consortium
Nature, ISSN 0028-0836, 09/2016, Volume 537, Issue 7621, pp. 508 - 514
Approximately one-third of all mammalian genes are essential for life. Phenotypes resulting from knockouts of these genes in mice have provided tremendous... 
MICRO-CT | MULTIDISCIPLINARY SCIENCES | DISEASE | GENOME-WIDE | MAMMALIAN GENE-FUNCTION | SCREENS | GLYCOGENIN-1 DEFICIENCY | IDENTIFICATION | EXPRESSION | MOUSE EMBRYO | RESOURCE | Genetic research | Phenotype | Research | High-throughput screening (Biochemical assaying) | Methods | Genotype & phenotype | Disease | Developmental biology | Genes | Genomes | Mutation | Embryos | knockout | embryonic lethal | mouse | KOMP | IMPC | EUCOMM
Journal Article
Nuclear Engineering and Design, ISSN 0029-5493, 08/2019, Volume 350, pp. 137 - 146
A project of Accelerator Driven Advanced Nuclear Energy System (ADANES) has been proposed in China. The system safety analysis code IMPC-transient was... 
Nuclear energy
Journal Article
by Bowl, Michael R and Simon, Michelle M and Ingham, Neil J and Greenaway, Simon and Santos, Luis and Cater, Heather and Taylor, Sarah and Mason, Jeremy and Kurbatova, Natalja and Pearson, Selina and Bower, Lynette R and Clary, Dave A and Meziane, Hamid and Reilly, Patrick and Minowa, Osamu and Kelsey, Lois and Allen, Sue and Clementson-Mobbs, Sharon and Codner, Gemma and Fray, Martin and Gardiner, Wendy and Joynson, Russell and Kenyon, Janet and Loeffler, Jorik and Nell, Barbara and Parker, Andrew and Quwailid, Deen and Stewart, Michelle and Walling, Alison and Zaman, Rumana and Chen, Chao-Kung and Conte, Nathalie and Matthews, Peter and Relac, Mike and Tudose, Ilinca and Warren, Jonathan and Le Marchand, Elise and El Amri, Amal and El Fertak, Leila and Ennah, Hamid and Ali-Hadji, Dalila and Ayadi, Abdel and Wattenhofer-Donze, Marie and Moulaert, David and Jacquot, Sylvie and André, Philippe and Birling, Marie-Christine and Pavlovic, Guillaume and Lalanne, Valérie and Lux, Aline and Riet, Fabrice and Mittelhaeuser, Christophe and Bour, Raphael and Guimond, Alain and Bam'Hamed, Chaouki and Leblanc, Sophie and Vasseur, Laurent and Selloum, Mohammed and Sorg, Tania and Ayabe, Shinya and Furuse, Tamio and Kaneda, Hideki and Kobayashi, Kimio and Masuya, Hiroshi and Miura, Ikuo and Obata, Yuichi and Suzuki, Tomohiro and Tamura, Masaru and Tanaka, Nobuhiko and Yamada, Ikuko and Yoshiki, Atsushi and Berberovic, Zorana and Bubshait, Mohammed and Cabezas, Jorge and Carroll, Tracy and Clark, Greg and Clarke, Shannon and Creighton, Amie and Danisment, Ozge and Eskandarian, Mohammad and Feugas, Patricia and Gertsenstein, Marina and Guo, Ruolin and Hunter, Jane and Jacob, Elsa and Lan, Qing and Laurin, Valerie and Law, Napoleon and MacMaster, Sue and Miller, David and Morikawa, Lily and Newbigging, Susan and Owen, Celeste and Penton, Patricia and Pereira, Monica and Qu, Dawei and Shang, Xueyuan and Sleep, Gillian and Sohel, Khondoker and Tondat, Sandra and ... and Int Mouse Phenotyping Consortium and International Mouse Phenotyping Consortium and The International Mouse Phenotyping Consortium
Nature Communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 886 - 11
Journal Article
Japanese Journal of Gastroenterological Surgery, ISSN 0386-9768, 2016, Volume 49, Issue 3, pp. 242 - 249
Journal Article
Current Osteoporosis Reports, ISSN 1544-1873, 4/2018, Volume 16, Issue 2, pp. 77 - 94
The international mouse phenotyping consortium (IMPC) is producing defined gene knockout mouse lines. Here, a phenotyping program is presented that is based on... 
Bone phenotyping | μCT | Medicine & Public Health | Orthopedics | Web portal | Histomorphometry | Epidemiology | IMPC and KOMP
Journal Article
DISEASE MODELS & MECHANISMS, ISSN 1754-8403, 08/2019, Volume 12, Issue 8, p. dmm038489
Primary ciliary dyskinesia (PCD) is a genetically heterogeneous disorder affecting normal structure and function of motile cilia, phenotypically manifested as... 
DIAGNOSIS | DYNEIN | LATERALITY DEFECTS | ELECTRON-MICROSCOPY | PATHOLOGY | MICE LACKING | FLOW | CELL BIOLOGY | IMPC | GENETICS | MOTILE | Gene knockout | CSF | X-ray gene expression imaging | MicroCT brain imaging | MUTATIONS | Cilia | INSIGHTS
Journal Article
by Huang, L and Ji, HF and Yin, L and Niu, XJ and Wang, YR and Liu, Y and Xuan, QJ and Li, LR and Zhang, H and Zhou, XP and Li, JT and Cui, CW and Yang, Y and An, WW and Zhang, QY
JOURNAL OF CANCER, ISSN 1837-9664, 2019, Volume 10, Issue 12, pp. 2800 - 2810
Invasive micropapillary carcinoma of the breast (IMPC) is a rare subtype of breast cancer that has a high frequency of lymph node (LN) involvement and... 
EMBOLI | GAMMA-CATENIN | Metastasis | E-CADHERIN | BETA-CATENIN | VARIANT | CANCER | Anti-anoikis | OVEREXPRESSION | ONCOLOGY | PATHWAY | Invasive micropapillary carcinoma of the breast (IMPC) | PI3K pathway | Plakoglobin
Journal Article
CURRENT OSTEOPOROSIS REPORTS, ISSN 1544-1873, 04/2018, Volume 16, Issue 2, pp. 77 - 94
Purpose of review The international mouse phenotyping consortium (IMPC) is producing defined gene knockout mouse lines. Here, a phenotyping program is... 
DRUG | DETERMINANTS | LOCI | MODEL | Histomorphometry | IDENTIFICATION | IMPC and KOMP | OSTEOPOROSIS | Bone phenotyping | GUT MICROBIOME | ENDOCRINOLOGY & METABOLISM | Web portal | GENERATION | PAGETS-DISEASE | DIFFERENTIATION | mu CT
Journal Article
BMC Cancer, ISSN 1471-2407, 12/2017, Volume 17, Issue 1, pp. 839 - 9
Background: Invasive micropapillary carcinoma (IMPC) of the breast is a rare variant of invasive ductal carcinoma (IDC). The prognosis of IMPC compared with... 
Breast cancer | Prognosis | IMPC | Survival | Invasive micropapillary carcinoma | Meta-analysis | BEHAVIOR | FOLLOW-UP | CANCER | VARIANT | ONCOLOGY | ESTROGEN | RECEPTORS | Medical research | Analysis | Medicine, Experimental | Development and progression | Metastasis | Health aspects
Journal Article
Conservation Genetics, ISSN 1566-0621, 8/2018, Volume 19, Issue 4, pp. 995 - 1005
Journal Article
DMM Disease Models and Mechanisms, ISSN 1754-8403, 2014, Volume 7, Issue 5, pp. 495 - 497
Mouse models are increasingly being used for the study of human disease, and the generation and functional characterisation of new models is underpinned by... 
Pathology | Mouse | IMPC | Phenotyping | MICE | HISTOPATHOLOGY | CELL BIOLOGY | Mice | Animals | Humans | Disease Models, Animal
Journal Article
METABOLITES, ISSN 2218-1989, 05/2019, Volume 9, Issue 5, p. 101
Mouse knockouts facilitate the study ofgene functions. Often, multiple abnormal phenotypes are induced when a gene is inactivated. The International Mouse... 
GC-MS | LC-MS | Metabolic phenotyping | GENE | metabolomics | IMPC | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENOME-WIDE | functional genomics | mouse knockouts | ASSOCIATION | lipidomics
Journal Article