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PLOS PATHOGENS, ISSN 1553-7366, 05/2016, Volume 12, Issue 5
Salmonella enterica replicates in macrophages through the action of effector proteins translocated across the vacuolar membrane by a type III secretion system... 
VIRULENCE PLASMID | PROTEIN | ENTERICA SEROVAR TYPHIMURIUM | ESCHERICHIA-COLI | PHOSPHOTHREONINE LYASE ACTIVITY | CHROMOSOMAL GENES | MICROBIOLOGY | POSTTRANSLATIONAL MODIFICATIONS | HOST ACTIN CYTOSKELETON | IMPORTIN-ALPHA | VIROLOGY | INNATE IMMUNE-RESPONSES | PARASITOLOGY
Journal Article
Current Opinion in Cell Biology, ISSN 0955-0674, 06/2018, Volume 52, pp. 30 - 42
Malfunction of nuclear–cytoplasmic transport contributes to many diseases including cancer. Defective nuclear transport leads to changes in both the... 
CELL LUNG-CANCER | MULTIPLE-MYELOMA | SELECTIVE INHIBITOR | STRUCTURAL BASIS | POOR-PROGNOSIS | RECEPTOR IMPORTIN-11 | ANTITUMOR-ACTIVITY | NUCLEAR-LOCALIZATION SIGNAL | IMPORTIN-ALPHA | NUCLEOCYTOPLASMIC TRANSPORT | CELL BIOLOGY | Cancer
Journal Article
JOURNAL OF VIROLOGY, ISSN 0022-538X, 12/2007, Volume 81, Issue 24, pp. 13469 - 13477
The Zaire ebolavirus protein VP24 was previously demonstrated to inhibit alpha/beta interferon (IFN-(alpha/beta)and IFN-gamma-induced nuclear accumulation of... 
NONHUMAN-PRIMATES | VIROLOGY | INFLUENZA-A VIRUS | DENDRITIC CELLS | HEMORRHAGIC-FEVER | I INTERFERON RESPONSE | AMINO-ACID MOTIF | NUCLEAR-LOCALIZATION SIGNAL | IMPORTIN-ALPHA | TRANSPORT FACTOR | MARBURG VIRUSES
Journal Article
AMERICAN JOURNAL OF PATHOLOGY, ISSN 0002-9440, 05/2013, Volume 182, Issue 5, pp. 1910 - 1921
Atherosclerosis is a chronic inflammatory disease of the arterial wall. NF-kappa B is a major regulator of inflammation that controls the expression of many... 
ACTIVATION | ATHEROGENESIS | NUCLEAR-FACTOR | INFLAMMATION | DISEASE | RECEPTOR | SMOOTH-MUSCLE-CELLS | PATHOLOGY | E-DEFICIENT MICE | IMPORTIN-ALPHA | EXPRESSION
Journal Article
INTERNATIONAL JOURNAL OF CANCER, ISSN 0020-7136, 04/2009, Volume 124, Issue 8, pp. 1829 - 1840
The Karyopherin proteins are involved in nucleo-cytoplasmic trafficking and are critical for protein anti RNA subcellular localization. Recent studies suggest... 
HUMAN-PAPILLOMAVIRUS TYPE-16 | Karyopherin alpha 2 | LEPTOMYCIN-B | NUCLEAR EXPORT | nuclear transport proteins | MINOR CAPSID PROTEIN | INTRAEPITHELIAL NEOPLASIA | cervical cancer | IMPORTIN-ALPHA | P53 | Crm1 | Karyopherin beta 1 | MESSENGER-RNA | ONCOLOGY | EXPRESSION | NUCLEOCYTOPLASMIC TRANSPORT
Journal Article
JOURNAL OF CELL SCIENCE, ISSN 0021-9533, 06/2019, Volume 132, Issue 11, p. jcs232819
Here, we show that the embryophyte (land-plant)-specific protein MACERATOR4 (MACET4) binds microtubules in vitro and in vivo, promotes microtubule... 
Nucleation | PROTEIN | TOBACCO BY-2 | Cytokinesis | IMPORTIN-ALPHA | DIVISION PLANE | CELL BIOLOGY | Phragmoplast | TPX2 | Microtubules | SPATIAL CONTROL | CELL-PLATE FORMATION | GAMMA-TUBULIN | VECTOR SET
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 11/2014, Volume 111, Issue 47, pp. E5039 - E5048
The circadian clock in mammalian cells is cell-autonomously generated during the cellular differentiation process, but the underlying mechanisms are not... 
PROTEIN | c-Myc | MULTIDISCIPLINARY SCIENCES | COORDINATION | cellular differentiation | circadian clock | IMPORTIN-ALPHA | OSCILLATOR | Dnmt1 | MAINTENANCE | Kpna2 (Importin-alpha 2) | RHYTHMS | MYC | EMBRYONIC STEM-CELLS | CRY1 | EXPRESSION
Journal Article
BBA - Molecular Cell Research, ISSN 0167-4889, 01/2020, Volume 1867, Issue 1, p. 118566
Nuclear-cytoplasmic trafficking of proteins is a highly regulated process that modulates multiple biological processes in eukaryotic cells. In , shuttling has... 
Importazole | Encystation | Gene regulation | Importin | Ivermectin | COMPLEX | LOCALIZATION SIGNAL | PROTEIN-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | IMPORTIN-ALPHA | BETA | CELL BIOLOGY | STRUCTURAL BASIS | SEQUENCE ALIGNMENT | BIOLOGY
Journal Article
NEUROREPORT, ISSN 0959-4965, 08/2019, Volume 30, Issue 11, pp. 760 - 764
Nuclear localization of ataxin-3 plays a fundamental role in seeding aggregation and the pathology of spinocerebellar ataxia type 3 (SCA3). However, very few... 
LOCALIZATION | divalproex sodium | PROTEIN | KARYOPHERIN ALPHA-3 | SCA3 | spinocerebellar ataxia type 3 | NUCLEAR-PORE COMPLEX | importin alpha 1 | NEUROSCIENCES | nuclear transport of ataxin-3
Journal Article