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1. Full Text Age-related changes in endothelial function and blood flow regulation
by Toda, Noboru
Pharmacology and Therapeutics, ISSN 0163-7258, 02/2012, Volume 133, Issue 2, pp. 159 - 176
Vascular endothelial dysfunction is regarded as a primary phenotypic expression of normal human aging. This senescence-induced disorder is the likely culprit... 
Endothelial nitric oxide synthase | Nitric oxide | Aging | Endothelial function | Endothelial progenitor cell | Telomere | Blood flow | PROGENITOR CELLS SENESCENCE | PROTEIN-KINASE PATHWAY | SKELETAL-MUSCLE ARTERIOLES | REFLEX CUTANEOUS VASODILATION | SPONTANEOUSLY HYPERTENSIVE-RATS | NITRIC-OXIDE SYNTHASE | BONE-MARROW-CELLS | NECROSIS-FACTOR-ALPHA | IMPROVES ERECTILE FUNCTION | PHARMACOLOGY & PHARMACY | CORONARY-ARTERY-DISEASE | Animals | Aging - physiology | Endothelium, Vascular - metabolism | Humans | Adult | Aged | Regional Blood Flow - physiology | Aging - metabolism | Endothelium, Vascular - physiology | Inositol | Amyloid beta-protein | Acetylcysteine | Glycerol | Superoxide | Cognition disorders | Plant lipids | Cyclic guanylic acid | Endothelium | Glycerin | Angiotensin | Stress (Psychology) | Vascular endothelial growth factor | Telomerase | Sexual disorders
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2. Full Text Randomized controlled trial of vitamin D supplement on endothelial function in patients with type 2 diabetes
by Yiu, Yuen-Fung and Yiu, Kai-Hang and Siu, Chung-Wah and Chan, Yap-Hang and Li, Sheung-Wai and Wong, Lai-Yung and Lee, Stephen W.L and Tam, Sidney and Wong, Eric W.K and Lau, Chu-Pak and Cheung, Bernard M.Y and Tse, Hung-Fat
Atherosclerosis, ISSN 0021-9150, 2012, Volume 227, Issue 1, pp. 140 - 146
Abstract Background Suboptimal vitamin D status is associated with endothelial dysfunction and an increased risk of cardiovascular diseases but it is unclear... 
Cardiovascular | Vitamin D | Endothelial function | Type 2 diabetes mellitus | C-REACTIVE PROTEIN | CARDIAC & CARDIOVASCULAR SYSTEMS | CARDIOVASCULAR EVENTS | 25-HYDROXYVITAMIN-D | RISK | FLOW-MEDIATED DILATION | BRACHIAL-ARTERY | ARTERIAL STIFFNESS | INSULIN-RESISTANCE | DISEASE | IMPROVES | PERIPHERAL VASCULAR DISEASE | Double-Blind Method | Pulse Wave Analysis | Humans | Middle Aged | Endothelium, Vascular - physiopathology | Endothelium, Vascular - drug effects | Male | Biomarkers - blood | Vitamin D - blood | Calcium - blood | C-Reactive Protein - metabolism | Cholecalciferol - administration & dosage | Diabetes Mellitus, Type 2 - physiopathology | Brachial Artery - physiopathology | Female | Vitamin D - analogs & derivatives | Aged | Brachial Artery - drug effects | Oxidative Stress - drug effects | Vasodilation - drug effects | Diabetes Mellitus, Type 2 - drug therapy | Type 2 diabetes | Diet therapy | Atherosclerosis | Calcifediol | Universities and colleges | Alfacalcidol | Public health | Diabetes therapy | Endothelium
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3. Full Text Simvastatin versus ezetimibe pleiotropic and lipid-lowering effects on endothelial function in humans
by Landmesser, Ulf and Bahlmann, Ferdinand and Mueller, Maja and Spiekermann, Stephan and Kirchhoff, Nina and Schulz, Svenja and Manes, Costantina and Fischer, Dieter and De Groot, Kirsten and Fliser, Danilo and Fauler, Günter and März, Winfried and Drexler, Helmut
Circulation, ISSN 0009-7322, 05/2005, Volume 111, Issue 18, pp. 2356 - 2363
Background-Statins may exert important pleiotropic effects, ie, improve endothelial function, independently of their impact on LDL cholesterol. In humans,... 
Heart failure | Superoxide dismutase | Statins | Stem cells | Endothelium | PROGENITOR CELLS | endothelium | stem cells | heart failure | CHRONIC HEART-FAILURE | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | NITRIC-OXIDE SYNTHASE | IMPROVES CARDIAC-FUNCTION | EXTRACELLULAR-SUPEROXIDE-DISMUTASE | STATIN THERAPY | statins | superoxide dismutase | OXIDATIVE STRESS GENERATION | PERIPHERAL VASCULAR DISEASE | A REDUCTASE INHIBITION | CORONARY-ARTERY-DISEASE | Endothelium, Vascular - cytology | Reactive Oxygen Species | Superoxide Dismutase - analysis | Simvastatin - administration & dosage | Humans | Middle Aged | Ezetimibe | Ascorbic Acid - administration & dosage | Endothelium, Vascular - drug effects | Male | Azetidines - pharmacology | Endothelium, Vascular - enzymology | Simvastatin - pharmacology | Azetidines - administration & dosage | Hematopoietic Stem Cells - cytology | Lipids - blood | Ascorbic Acid - pharmacology | Female | Radial Artery - drug effects | Vasodilation - drug effects | Radial Artery - physiology | Anticholesteremic Agents - pharmacology
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4. Full Text Vascular Endothelial Function and Hypertension: Insights and Directions
by Dharmashankar, Kodlipet and Widlansky, Michael E
Current Hypertension Reports, ISSN 1522-6417, 12/2010, Volume 12, Issue 6, pp. 448 - 455
Hypertension contributes significantly to worldwide cardiovascular morbidity and mortality. Hypertension appears to have a complex association with endothelial... 
Hypertension | Oxidative stress | Internal Medicine | Inflammation | Endothelium | Mitochondria | Medicine & Public Health | Sodium | Mineralocorticoid receptor | Nitric oxide | NADPH oxidase | Cardiovascular risk | Cardiology | PROGENITOR CELLS | DEPENDENT VASODILATION | SPIRONOLACTONE IMPROVES | CONVERTING-ENZYME-INHIBITORS | BLOOD-PRESSURE | FLOW-MEDIATED VASODILATION | NITRIC-OXIDE | PERIPHERAL VASCULAR DISEASE | ALDOSTERONE EXCESS | PERIVASCULAR ADIPOSE-TISSUE | Antihypertensive Agents - pharmacology | Reactive Oxygen Species - metabolism | Humans | Oxidative Stress - physiology | Risk Factors | Rats | Endothelium, Vascular - drug effects | Clinical Trials as Topic | Hypolipidemic Agents - pharmacology | Hypertension - physiopathology | Hypertension - metabolism | Animals | Endothelium-Dependent Relaxing Factors - metabolism | Endothelium, Vascular - metabolism | Diet, Sodium-Restricted | Endothelium, Vascular - pathology | Models, Animal | Blood Pressure - drug effects | Mice | Hypertension - epidemiology | Hypertension - therapy | Oxidases | Mitochondrial DNA | Endothelin
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5. Full Text Anti-TNF-alpha agents and endothelial function in rheumatoid arthritis: A systematic review and meta-analysis
by Ursini, Francesco and Leporini, Christian and Bene, Fabiola and D'Angelo, Salvatore and Mauro, Daniele and Russo, Emilio and De Sarro, Giovambattista and Olivieri, Ignazio and Pitzalis, Costantino and Lewis, Myles and Grembiale, Rosa Daniela
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 5346 - 10
Rheumatoid arthritis (RA) has been associated with endothelial dysfunction, a pathophysiological feature of atherosclerosis. Our aim was to determine whether... 
RISK-FACTORS | THERAPY | CARDIOVASCULAR EVENTS | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | ATHEROSCLEROSIS | METHOTREXATE | IMPROVES | DYSFUNCTION | BODY INSULIN SENSITIVITY | PSORIATIC-ARTHRITIS | Tumor Necrosis Factor-alpha - metabolism | Arthritis, Rheumatoid - drug therapy | Humans | Treatment Outcome | Endothelial Cells - pathology | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Arthritis, Rheumatoid - pathology | Endothelial Cells - drug effects | Immunologic Factors - therapeutic use | Tumor necrosis factor-α | Low density lipoprotein | Rheumatoid arthritis | Arteriosclerosis | Measurement techniques | Meta-analysis
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6. Full Text Effects of acute exercise on endothelial function in patients with abdominal aortic aneurysm
by Bailey, Tom G and Perissiou, Maria and Windsor, Mark T and Schulze, Karl and Nam, Michael and Magee, Rebecca and Leicht, Anthony S and Green, Daniel J and Greaves, Kim and Golledge, Jonathan and Askew, Christopher D
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 01/2018, Volume 314, Issue 1, pp. H19 - H30
Endothelial dysfunction is observed in patients with abdominal aortic aneurysm (AAA), who have increased risk of cardiovascular events and mortality. This... 
Exercise | Flow-mediated dilation | Endothelial function | Abdominal aortic aneurysm | Cardiovascular risk | endothelial function | IMPROVES AEROBIC FITNESS | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | DEPENDENT VASODILATION | CARDIOVASCULAR EVENTS | exercise | abdominal aortic aneurysm | HIGH-INTENSITY | CARDIORESPIRATORY FITNESS | BRACHIAL-ARTERY | SHEAR RATE | HANDGRIP EXERCISE | NITRIC-OXIDE | PERIPHERAL VASCULAR DISEASE | flow-mediated dilation | cardiovascular risk | Exercise Therapy - methods | Heart Rate | Cross-Sectional Studies | Humans | Middle Aged | Endothelium, Vascular - physiopathology | Aortic Aneurysm, Abdominal - diagnostic imaging | Male | Treatment Outcome | Aortic Aneurysm, Abdominal - therapy | Recovery of Function | Vasodilation | Brachial Artery - diagnostic imaging | Arterial Pressure | Time Factors | Aortic Aneurysm, Abdominal - physiopathology | Endothelium, Vascular - diagnostic imaging | Aged, 80 and over | Brachial Artery - physiopathology | Aged | Queensland
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7. Full Text Acute Effects of High-Fat Meals Enriched With Walnuts or Olive Oil on Postprandial Endothelial Function
by Cortés, Berenice and Núñez, Isabel and Cofán, Montserrat and Gilabert, Rosa and Pérez-Heras, Ana and Casals, Elena and Deulofeu, Ramón and Ros, Emilio
Journal of the American College of Cardiology, ISSN 0735-1097, 10/2006, Volume 48, Issue 8, pp. 1666 - 1671
Acute Effects of High-Fat Meals Enriched With Walnuts or Olive Oil on Postprandial Endothelial Function Berenice Cortés, Isabel Núñez, Montserrat Cofán, Rosa... 
BRACHIAL-ARTERY VASOACTIVITY | WOMEN | CARDIAC & CARDIOVASCULAR SYSTEMS | DIET | MARKER | HYPERCHOLESTEROLEMIC MEN | DISEASE | IMPROVES | DYSFUNCTION | RANDOMIZED CROSSOVER TRIAL | IMPAIRMENT | Cell Adhesion Molecules - blood | Nuts | Juglans | Humans | Endothelium, Vascular - physiopathology | Inflammation Mediators - blood | E-Selectin - blood | Olive Oil | Regional Blood Flow | Vasodilation | Cross-Over Studies | Dose-Response Relationship, Drug | Osmolar Concentration | Dietary Fats - pharmacology | Fasting - blood | Dietary Fats - administration & dosage | Postprandial Period | Triglycerides - blood | Brachial Artery - physiopathology | Hypercholesterolemia - physiopathology | Plant Oils | Lipoproteins, LDL - blood | Cytokines - blood | Monounsaturated fatty acids | Hypercholesterolemia | Gastrointestinal agents | Analysis | Nitric oxide | Linolenic acids | Wetland flora | Olive oil | Fatty acids | Endothelium | Saturated fatty acids | Antioxidants | Meals | Variance analysis | Low density lipoprotein | Cholesterol
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8. Full Text Effect of Saxagliptin on Endothelial Function in Patients with Type 2 Diabetes: A Prospective Multicenter Study
by Kajikawa, M and Maruhashi, T and Hidaka, T and Matsui, S and Hashimoto, H and Takaeko, Y and Nakano, Y and Kurisu, S and Kihara, Y and Yusoff, FM and Kishimoto, S and Chayama, K and Goto, C and Noma, K and Nakashima, A and Hiro, T and Hirayama, A and Shiina, K and Tomiyama, H and Yagi, S and Amano, R and Yamada, H and Sata, M and Higashi, Y
SCIENTIFIC REPORTS, ISSN 2045-2322, 07/2019, Volume 9, Issue 1, pp. 10206 - 7
The dipeptidyl peptidase-4 inhibitor saxagliptin is a widely used antihyperglycemic agent in patients with type 2 diabetes. The purpose of this study was to... 
PROGENITOR CELLS | IMPROVES NEOVASCULARIZATION | DIPEPTIDYL PEPTIDASE-4 INHIBITOR | OXIDATIVE STRESS | CARDIOVASCULAR EVENTS | GLUCOSE | MULTIDISCIPLINARY SCIENCES | SITAGLIPTIN | NITRIC-OXIDE | MECHANISMS | OUTCOMES | Creatinine | Urine | Peptidase | Diabetes mellitus | Diabetes | Diabetes mellitus (non-insulin dependent) | Patients | Vasodilation | Cholesterol
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9. Full Text Periodontal therapy and endothelial function in coronary artery disease: A randomized controlled trial
by Saffi, Marco Aurélio L and Rabelo‐Silva, Eneida R and Polanczyk, Carisi A and Furtado, Mariana V and Montenegro, Marlon M and Ribeiro, Ingrid W. J and Kampits, Cassio and Rösing, Cassiano K and Haas, Alex N
Oral Diseases, ISSN 1354-523X, 10/2018, Volume 24, Issue 7, pp. 1349 - 1357
Objective To assess the effects of periodontal treatment on endothelial function in patients with coronary artery disease. Materials and Methods A randomized... 
atherosclerosis | vascular endothelium | flow‐mediated dilation | periodontitis | flow-mediated dilation | GUIDELINES | MARKERS | RISK | ADHESION MOLECULES | CARE | HEART-DISEASE | BRACHIAL-ARTERY | DENTISTRY, ORAL SURGERY & MEDICINE | IMPROVES | DYSFUNCTION | ASSOCIATION | Single-Blind Method | Root Planing | Humans | Middle Aged | Endothelium, Vascular - physiopathology | Periodontitis - therapy | Male | Oral Hygiene | Vascular Cell Adhesion Molecule-1 - blood | Coronary Artery Disease - physiopathology | Coronary Artery Disease - complications | P-Selectin - blood | Female | Intercellular Adhesion Molecule-1 - blood | Aged | Periodontitis - complications | Vasodilation - physiology | Patient Education as Topic | Clinical trials | Toiletries industry | Coronary heart disease | Cardiac patients | Atherosclerosis | Endothelium | Periodontitis | Oral hygiene | Coronary vessels | Coronary artery | Cardiovascular disease | Scaling | Patients | Heart diseases | Vasodilation
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10. Attenuated endothelial function is associated with decreased endothelial progenitor cells and nitric oxide in premenopausal diabetic women
by Liu, Juan and Hu, Da-Jun and Yan, Huiyang and Liu, Jianbin and Ai, Xixong and Ren, Zi and Zeng, Haitao and He, Hao and Yang, Zhen
Molecular Medicine Reports, ISSN 1791-2997, 11/2018, Volume 18, Issue 5, pp. 4666 - 4674
Previous studies have demonstrated that the deleterious effect of diabetes mellitus (DM) on the risk of cardiovascular disease also occurs in premenopausal... 
Endothelial function | Premenopausal women | Nitric oxide | Endothelial progenitor cells | endothelial function | MEDICINE, RESEARCH & EXPERIMENTAL | CAPACITY | nitric oxide | OXIDATIVE STRESS | RISK | MELLITUS | REPAIR | ONCOLOGY | SIGNALING PATHWAY | endothelial progenitor cells | DISEASE | premenopausal women | IMPROVES | DYSFUNCTION | UP-REGULATION
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11. Full Text The effect of liraglutide on endothelial function in patients with type 2 diabetes
by Nandy, Debashis and Johnson, Christopher and Basu, Rita and Joyner, Michael and Brett, Jason and Svendsen, Claus Bo and Basu, Ananda
Diabetes & Vascular Disease Research, ISSN 1479-1641, 11/2014, Volume 11, Issue 6, pp. 419 - 430
This single-centre, 12-week, double-blind, placebo-controlled trial assessed how the human glucagon-like-peptide 1 analogue liraglutide impacted endothelial... 
endothelial function | liraglutide | Glucagon-like peptide-1 | GLP-1 | EXENATIDE | FLOW | ENDOCRINOLOGY & METABOLISM | NITRIC-OXIDE | IMPROVES | PERIPHERAL VASCULAR DISEASE | NONDIABETIC SUBJECTS | DYSFUNCTION | RECEPTOR AGONIST | CORONARY-ARTERY-DISEASE | C-Peptide - blood | Humans | Middle Aged | Body Weight - drug effects | Endothelium, Vascular - drug effects | Male | Insulin - blood | Glucagon - blood | Lipids - blood | Female | Blood Pressure - drug effects | Hypoglycemic Agents - therapeutic use | Glucagon-Like Peptide 1 - analogs & derivatives | Glucagon-Like Peptide 1 - pharmacology | Nitroprusside | Hypoglycemic Agents - pharmacology | Blood Glucose - drug effects | Diabetes Mellitus, Type 2 - blood | Acetylcholine | Aged | Glucose Clamp Technique | Diabetes Mellitus, Type 2 - drug therapy | Liraglutide | Plethysmography | Glucagon-Like Peptide 1 - therapeutic use
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12. Full Text Testosterone preserves endothelial function through regulation of S1P1/Akt/FOXO3a signalling pathway in the rat corpus cavernosum
by Cui, Kai and Li, Rui and Liu, Kang and Wang, Tao and Liu, Jihong and Rao, Ke
Andrologia, ISSN 0303-4569, 02/2019, Volume 51, Issue 1, pp. e13173 - n/a
The aim of the study was to investigate how testosterone regulating endothelial function in the corpus cavernosum of rats. A total of 32 male Sprague‐Dawley... 
endothelial function | testosterone | sphingosine‐1‐phosphate | sphingosine-1-phosphate | MYOCARDIAL-INFARCTION | ANDROLOGY | LATE-ONSET HYPOGONADISM | IDENTIFICATION | SEXUAL FUNCTION | IMPROVES ERECTILE FUNCTION | PATHOGENESIS | THERAPY | CELL JUNCTIONS | MEN | Phosphorylation | Rats | Endothelium, Vascular - drug effects | Male | Testosterone - pharmacology | Rats, Sprague-Dawley | Forkhead Box Protein O3 - metabolism | Penis - drug effects | Testosterone - metabolism | Animals | Castration | Penis - metabolism | Signal Transduction - drug effects | Endothelium, Vascular - metabolism | Signal Transduction - physiology | Proto-Oncogene Proteins c-akt - metabolism | Receptors, Lysosphingolipid - metabolism | Serum levels | Testosterone | Oxidative stress | Signal transduction | Androgens | AKT protein | Hormone replacement therapy | Supplementation | FOXO3 protein
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