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Annals of Surgery, ISSN 0003-4932, 12/2014, Volume 260, Issue 6, pp. 1138 - 1146
Journal Article
Journal of Clinical Endocrinology and Metabolism, ISSN 0021-972X, 05/2017, Volume 102, Issue 5, pp. 1631 - 1641
Context: Leiomyomas have abundant extracellular matrix (ECM), with upregulation of versican, a large proteoglycan. Objective: We investigated ADAMTS (a... 
CELLS | PROTEOGLYCANS | PROTEIN | ROLES | EXTRACELLULAR-MATRIX PRODUCTION | ENDOCRINOLOGY & METABOLISM | NORMAL MYOMETRIUM | FIBROIDS | HORMONES | Immunohistochemistry | Up-Regulation | ADAMTS4 Protein - genetics | Uterine Neoplasms - pathology | Humans | Middle Aged | Extracellular Matrix - metabolism | Apoptosis - genetics | Leiomyoma - metabolism | Receptors, Progesterone - genetics | Asymptomatic Diseases | RNA, Messenger - metabolism | Gene Knockdown Techniques | Receptors, Progesterone - metabolism | Leiomyoma - pathology | Versicans - genetics | In Situ Hybridization | Proteolysis | Myometrium - metabolism | Adult | Estrogen Receptor alpha - metabolism | Female | Cell Proliferation - genetics | Uterine Neoplasms - metabolism | ADAMTS Proteins - metabolism | Hemoglobins - metabolism | Menorrhagia - etiology | ADAMTS4 Protein - metabolism | Tumor Burden | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Estrogen Receptor alpha - genetics | Cell Line, Tumor | RNA, Small Interfering | Versicans - metabolism | ADAMTS Proteins - genetics | Protein Isoforms - genetics | Cell proliferation | Alternative splicing | Estrogens | Estrogen receptors | Reverse transcription | Smooth muscle | Bleeding | Western blotting | Receptors | Uterus | Hemoglobin | Extracellular matrix | Metalloproteinase | Versican | Thrombospondin | Myometrium | Menstruation | Muscles | Fibroids | siRNA | Hysterectomy | Progesterone receptors | Polymerase chain reaction | Ribonucleic acids | Cell lines | Isoforms | Progesterone | Apoptosis
Journal Article
Methods in molecular biology (Clifton, N.J.), ISSN 1064-3745, 2014, Volume 1169, pp. 27 - 35
RIG-I is a key pattern recognition receptor that recognizes cytoplasmic viral RNA. Upon ligand binding, it undergoes a conformational change that induces an... 
Innate immunity | RIG-I | Viral RNA | In situ proteolysis | ATPase | Crystallization | Animals | RNA, Viral - chemistry | Proteolysis | Crystallography, X-Ray | Protein Conformation | Mice | DEAD-box RNA Helicases - metabolism | Immunity, Innate | DEAD-box RNA Helicases - chemistry
Journal Article
Methods in molecular biology (Clifton, N.J.), ISSN 1064-3745, 2014, Volume 1140, pp. 179 - 188
In situ proteolysis is the method of proactively adding tiny amounts of nonspecific proteases to aid in the crystallization of proteins and protein... 
Chymotrypsin | Nonspecifi c protease | Trypsin | Limited proteolysis | In situ proteolysis | Crystallization | Crystallography, X-Ray | High-Throughput Screening Assays | Proteins - chemistry | Proteolysis | Molecular Biology - methods
Journal Article
Acta Crystallographica Section F, ISSN 2053-230X, 05/2018, Volume 74, Issue 5, pp. 300 - 306
Journal Article
Journal Article
Journal Article
Journal Article
Brain Research, ISSN 0006-8993, 2012, Volume 1471, pp. 102 - 117
Abstract A pathological hallmark of Alzheimer's disease (AD) is the presence within neurons and the interneuronal space of aggregates of β-amyloid (Aβ)... 
Neurology | Parkinson's disease | Pepstatin A | Alzheimer's disease | Chloroquine | Lysosome | BETA-SECRETASE | ALZHEIMERS-DISEASE | TRAFFICKING | AMYLOID PRECURSOR PROTEIN | PATHOLOGY | SUBSTANTIA-NIGRA | NEUROSCIENCES | PATHWAY | EXTRAPYRAMIDAL SIGNS | CATHEPSIN-D | GAMMA-SECRETASE | Apoptosis - drug effects | Humans | Apoptosis - genetics | Green Fluorescent Proteins - genetics | Pepstatins - pharmacology | Dose-Response Relationship, Drug | Mitochondrial Membranes - drug effects | Chloroquine - pharmacology | Protease Inhibitors - pharmacology | Proteolysis - drug effects | Transfection - methods | Amyloid beta-Peptides - metabolism | Amyloid beta-Protein Precursor - metabolism | Phorbol Esters - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Neuroblastoma - pathology | Carbamates - pharmacology | In Situ Nick-End Labeling | Lysosomes - drug effects | Dipeptides - pharmacology | Endocytosis - drug effects | RNA, Small Interfering - pharmacology | Dopamine - pharmacology | bcl-2-Associated X Protein - metabolism | Cathepsin D - metabolism | Amyloid Precursor Protein Secretases - metabolism | Amyloid beta-Protein Precursor - genetics | Animals | Neuroblastoma - ultrastructure | Cell Line, Tumor | Protein Biosynthesis - drug effects | Mice | Phorbol esters | Dopamine | Peptides | Proteases | Proteolysis | Amyloid beta-protein | Fluorescein | Phenols | Fluorescence | Apoptosis | Index Medicus
Journal Article