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Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 8/2010, Volume 107, Issue 35, pp. 15373 - 15378
We describe the integration of microfluidic selection with highthroughput DNA sequencing technology for rapid and efficient discovery of nucleic acid aptamers... 
Polymerase chain reaction | Molecules | DNA | Fluorescence | Nucleotide aptamers | Ligands | Libraries | Washing | Nucleic acids | Sequencing | MicroMagnetic separation device | High-throughput DNA sequencing | Quantitative selection of aptamers through sequencing | PDGF-BB | HUMAN THROMBIN | CANCER CELLS | MULTIDISCIPLINARY SCIENCES | BLOOD-SERUM | IN-VITRO SELECTION | RNA MOLECULES | MICROMAGNETIC SELECTION | MicroMagnetic Separation device | LIGANDS | Quantitative Selection of Aptamers through Sequencing | GENERATION | GROWTH-FACTOR | high-throughput DNA sequencing | SELEX | Binding, Competitive | Reproducibility of Results | Gene Library | Proto-Oncogene Proteins c-sis | DNA, Single-Stranded - metabolism | Aptamers, Nucleotide - chemistry | Aptamers, Nucleotide - metabolism | Platelet-Derived Growth Factor - genetics | DNA, Single-Stranded - chemistry | DNA, Single-Stranded - genetics | Aptamers, Nucleotide - genetics | Platelet-Derived Growth Factor - metabolism | Base Sequence | Cloning, Molecular | Protein Binding | Kinetics | SELEX Aptamer Technique - methods | Microfluidics - methods | Sequence Analysis, DNA - methods | Amino acid sequence | Research | Chemical properties | Microfluidics | Methods | Protein binding | Integration | platelet-derived growth factor BB | Aptamers | nucleic acids | copy number | DNA sequencing | Biological Sciences
Journal Article
Scientific reports, ISSN 2045-2322, 2014, Volume 4, Issue 1, p. 3894
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 10/2016, Volume 113, Issue 43, pp. 12076 - 12081
Journal Article
Angewandte Chemie (International ed.), ISSN 1433-7851, 2019, Volume 58, Issue 9, pp. 2739 - 2743
Selection of aptamers from oligonucleotide libraries currently requires multiple rounds of alternating steps of partitioning of binders from nonbinders and enzymatic amplification of all collected oligonucleotides... 
one-step selections | oligonucleotides | aptamers | DNA libraries | ideal-filter capillary electrophoresis | DNA APTAMERS | SYSTEMATIC EVOLUTION | IN-VITRO SELECTION | CHEMISTRY, MULTIDISCIPLINARY | EQUILIBRIUM MIXTURES | SINGLE-CYCLE | PCR BIAS | LIGANDS | AFFINITY | SELEX SELECTION | EXPONENTIAL ENRICHMENT | Enzymes | Electrophoresis | Genomic libraries | Proteins | Partitioning | Capillary electrophoresis | Aptamers | Oligonucleotides | Binders
Journal Article
Molecular therapy. Nucleic acids, ISSN 2162-2531, 2015, Volume 4, Issue 1, pp. e223 - e223
Journal Article
Reproductive BioMedicine Online, ISSN 1472-6483, 2013, Volume 27, Issue 5, pp. 539 - 546
Journal Article
Annual review of biochemistry, ISSN 0066-4154, 6/2018, Volume 87, Issue 1, pp. 479 - 502
Journal Article
Journal Article