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Journal of Neuroscience, ISSN 0270-6474, 03/2004, Volume 24, Issue 10, pp. 2527 - 2534
Journal Article
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 04/2017, Volume 18, Issue 4, pp. 861 - 861
High incidence rate of Alzheimer's disease (AD) is observed in patients with type 2 diabetes. Aggregated beta-amyloid (A beta) and hyperphosphorylated tau are... 
Tau phosphorylation | PP2A | Diabetes | Methylation | Folic acid | HOMOCYSTEINE METABOLISM | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | RATS | PROTEIN PHOSPHATASE 2A | CHEMISTRY, MULTIDISCIPLINARY | B VITAMIN DEFICIENCY | INCREASED RISK | methylation | HYPERPHOSPHORYLATION | DYSFUNCTION | folic acid | tau phosphorylation | diabetes | EXPRESSION | BRAIN | Folic Acid - pharmacology | Diabetes Mellitus, Experimental - genetics | tau Proteins - metabolism | Male | Glycogen Synthase Kinase 3 beta - metabolism | Blood Glucose - drug effects | DNA (Cytosine-5-)-Methyltransferases - metabolism | Diabetes Mellitus, Experimental - blood | Gene Expression Regulation - drug effects | DNA (Cytosine-5-)-Methyltransferases - genetics | Animals | Methylation - drug effects | Folic Acid - blood | Protein Phosphatase 2 - metabolism | Folic Acid - metabolism | Mice | Phosphorylation - drug effects | Diabetes Mellitus, Experimental - metabolism | Brain | Phosphorylation | Animal models | Phosphoprotein phosphatase | Streptozocin | Cognitive ability | Kinases | Incidence | Rodents | Vitamin B | Alzheimer's disease | Deoxyribonucleic acid--DNA | Neurodegenerative diseases | Glycogen | Diabetes mellitus | DNMT1 protein | Methionine | Glycogen synthase kinase 3 | Pharmacology | Gene expression | Chemical compounds | Patients | Polymerase chain reaction | Acids | Tau protein | β-Amyloid | DNA methyltransferase | Protein phosphatase | Alzheimers disease | Homocysteine | Index Medicus
Journal Article
HUMAN MOLECULAR GENETICS, ISSN 0964-6906, 08/2010, Volume 19, Issue 15, pp. 2947 - 2957
The amyloid-beta 42 (A beta 42) peptide has been suggested to promote tau phosphorylation and toxicity in Alzheimer's disease ( AD) pathogenesis; however, the... 
PROTEIN-TAU | NEUROFIBRILLARY TANGLES | INCREASED OXIDATIVE DAMAGE | INDUCED NEURODEGENERATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | DNA-DAMAGE | GENETICS & HEREDITY | PAIRED HELICAL FILAMENTS | A-BETA | CELL-CYCLE | MILD COGNITIVE IMPAIRMENT | CYCLIN-DEPENDENT KINASE-5
Journal Article
by Zhang, J and Lin, YB and Dai, XM and Fang, WT and Wu, XL and Chen, XC
FASEB JOURNAL, ISSN 0892-6638, 06/2019, Volume 33, Issue 6, pp. 7748 - 7757
Aging and apolipoprotein E4 (ApoE4) can increase the risk of cognitive impairment and neurodegenerative disorders, including Alzheimer's disease (AD), and... 
INCREASED TAU PHOSPHORYLATION | ACTIVATED PROTEIN-KINASE | INTRANASAL INSULIN | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | COGNITIVE IMPAIRMENT | SYNAPTIC PLASTICITY | TRANSLATIONAL CONTROL | CELL BIOLOGY | INSULIN-RECEPTOR | insulin signaling | SIGNALING PATHWAY | BIOLOGY | AMPK | LONG-TERM POTENTIATION | tau phosphorylation
Journal Article
Pharmacology, Biochemistry and Behavior, ISSN 0091-3057, 06/2012, Volume 101, Issue 4, pp. 564 - 574
Diabetes increases the risk of Alzheimer's disease (AD). The pathological hallmarks for AD brains are extracellular amyloid plaques formed by β-amyloid peptide... 
Tau phosphorylation | Mice | Diabetes | Metformin | Alzheimer disease | ANTIGEN RETRIEVAL | DB/DB MICE | PROTEIN-KINASE | NEUROSCIENCES | TAU-HYPERPHOSPHORYLATION | GLYCOGEN-SYNTHASE KINASE-3-BETA | A beta | INCREASED RISK | IN-VIVO | A-BETA | BEHAVIORAL SCIENCES | PHARMACOLOGY & PHARMACY | LACTIC-ACIDOSIS | LONG-TERM POTENTIATION | Alzheimer Disease - etiology | Memory - drug effects | Phosphorylation | Vesicular Transport Proteins - metabolism | Fear - drug effects | tau Proteins - metabolism | JNK Mitogen-Activated Protein Kinases - metabolism | Male | Neurofibrillary Tangles - drug effects | Hippocampus - drug effects | Alzheimer Disease - pathology | Amyloid beta-Peptides - metabolism | Leptin - pharmacology | Alzheimer Disease - psychology | Diabetes Mellitus, Type 2 - complications | Drug Resistance | Disease Models, Animal | Neurofibrillary Tangles - pathology | Diabetes Mellitus, Type 2 - psychology | Synaptophysin | Plaque, Amyloid - pathology | Conditioning (Psychology) - drug effects | Metformin - pharmacology | Alzheimer Disease - drug therapy | Hippocampus - pathology | Maze Learning - drug effects | Hypoglycemic Agents - pharmacology | Plaque, Amyloid - drug therapy | Animals | Protein Phosphatase 2 - metabolism | Mice, Obese | Diabetes Mellitus, Type 2 - pathology | Diabetes Mellitus, Type 2 - drug therapy | Hippocampus - physiopathology | Type 2 diabetes | Proteins | Obesity | Brain | Hyperglycemia | Peptides | Analysis | Hypoglycemic agents | Alzheimer's disease | Index Medicus
Journal Article
by Yao, XQ and Zhang, XX and Yin, YY and Liu, B and Luo, DJ and Liu, D and Chen, NN and Ni, ZF and Wang, X and Wang, Q and Wang, JZ and Liu, GP
BIOCHEMICAL JOURNAL, ISSN 0264-6021, 07/2011, Volume 437, pp. 335 - 344
Journal Article
Trends in Molecular Medicine, ISSN 1471-4914, 2010, Volume 16, Issue 6, pp. 287 - 294
Journal Article
Journal Article
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, ISSN 0305-1846, 06/2015, Volume 41, Issue 4, pp. 428 - 444
Journal Article