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indoleamine-2,3-dioxygenase (175) 175
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indoleamine 2,3-dioxygenase (82) 82
animals (66) 66
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indoleamine-pyrrole 2,3,-dioxygenase - metabolism (41) 41
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chemistry, medicinal (24) 24
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indoleamine-pyrrole 2,3,-dioxygenase - immunology (14) 14
indoleamine‐2,3‐dioxygenase (14) 14
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CLINICAL CANCER RESEARCH, ISSN 1078-0432, 01/2020, Volume 26, Issue 1, pp. 282 - 289
Purpose: We recently reported that indoleamine 2, 3-dioxygen-ase (IDO) activity is significantly correlated with more distant metastasis and worse survival.... 
TRYPTOPHAN | CHEMORADIATION | INDOLEAMINE-2,3-DIOXYGENASE | TOXICITY | ONCOLOGY
Journal Article
Cancer Research, ISSN 0008-5472, 11/2012, Volume 72, Issue 21, pp. 5435 - 5440
Journal Article
JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 02/2020, Volume 63, Issue 4, pp. 1642 - 1659
Indoleamine 2,3-dioxygenase (IDO1) inhibitors are speculated to be useful in cancer immunotherapy, but a phase III clinical trial of the most advanced IDO1... 
TRYPTOPHAN | REFINEMENT | DESIGN | INDOLEAMINE-2,3-DIOXYGENASE | CHEMISTRY, MEDICINAL | MECHANISM | COMPLEXES | CRYSTAL-STRUCTURES | DERIVATIVES | EXPRESSION | IDO1
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 02/2020, Volume 188, p. 111985
Indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO) are involved in the key steps of tryptophan metabolism and are potential new targets... 
Tryptophan 2,3-dioxygenase | Indole-2-carboxylic acid | Indoleamine 2,3-dioxygenase 1 | Dual inhibitors | CHEMISTRY, MEDICINAL | CRYSTAL-STRUCTURE | INDOLEAMINE 2,3-DIOXYGENASE | IDENTIFICATION | POTENT INHIBITORS | TRYPTOPHAN CATABOLISM | DISCOVERY | CHALLENGES | INDOLEAMINE-2,3-DIOXYGENASE | ENZYME | TDO
Journal Article
Blood, ISSN 0006-4971, 04/2010, Volume 115, Issue 17, pp. 3520 - 3530
Journal Article
RSC Advances, ISSN 2046-2069, 2016, Volume 6, Issue 9, pp. 7575 - 7581
The indoleamine 2,3-dioxygenase (IDO) mediated kynurenine pathway of tryptophan degradation is identified as an important immune effector pathway in tumor... 
Journal Article
Behavioural Brain Research, ISSN 0166-4328, 07/2015, Volume 288, pp. 71 - 78
•Estrogen ameliorates depression-like behavior in ovariectomized rats.•Ovariectomy results in increased IDO expression and decreased 5-HT in... 
Depression | Inflammation | Estrogen | Indoleamine-2,3-dioxygenase (IDO) | ACTIVATION | INDOLEAMINE 2,3-DIOXYGENASE | FRONTAL-CORTEX | MILD STRESS | NEUROSCIENCES | FEMALE | NEUROINFLAMMATION | ESTRADIOL | RECEPTOR-BETA | BEHAVIORAL SCIENCES | CENTRAL-NERVOUS-SYSTEM | SEX-DIFFERENCES | Physiological aspects | Phenols | Brain
Journal Article
World Journal of Gastroenterology, ISSN 1007-9327, 05/2018, Volume 24, Issue 20, pp. 2181 - 2190
AIM To evaluate indoleamine-2,3-dioxygenase 1/cyclooxygenase 2 (IDO1/COX2) expression as an independent prognostic biomarker for colorectal cancer (CRC)... 
3-dioxygenase 1 | Prognosis | Indoleamine-2 | Cyclooxygenase 2 | Colorectal cancer | Indoleamine-2,3-dioxygenase 1 | 2,3-DIOXYGENASE 1 EXPRESSION | INHIBITION | THERAPY | IMMUNOTHERAPY | INDOLEAMINE 2,3-DIOXYGENASE | TUMOR | GASTROENTEROLOGY & HEPATOLOGY | Retrospective Study
Journal Article
Journal of Pharmaceutical and Biomedical Analysis, ISSN 0731-7085, 06/2019, Volume 170, pp. 220 - 227
[Display omitted] •Quantitative MSI and LC–MS/MS analysis were used on CT26 mouse tumor model.•IDO1 inhibitor effects were evaluated on the tumor... 
Epacadostat | Quantitative mass spectrometry imaging | Pharmacodynamics | Target exposure | Drug distribution | Indoleamine-2,3-dioxygenase | TRYPTOPHAN | PREDICTS | CHEMISTRY, ANALYTICAL | SECTIONS | REGIONAL QUANTITATIVE-DETERMINATION | DISCOVERY | LACTATE | PHARMACOLOGY & PHARMACY | H-1-MRS
Journal Article
by Ye, ZX and Yue, LX and Shi, JC and Shao, MM and Wu, T
JOURNAL OF CANCER, ISSN 1837-9664, 2019, Volume 10, Issue 12, pp. 2771 - 2782
Kynurenine (Kyn) pathway is a significant metabolic pathway of tryptophan (Trp). The metabolites of the Kyn pathway are closely correlated with numerous... 
INDOLEAMINE 2,3-DIOXYGENASE | Tryptophan | IDENTIFICATION | PROGNOSTIC VALUE | DISCOVERY | HEPATIC TRYPTOPHAN 2,3-DIOXYGENASE | INDOLEAMINE-2,3-DIOXYGENASE | ONCOLOGY | IDO | PATHWAY | Kynurenine | 3-DIOXYGENASE | INHIBITORS | EXPRESSION | TDO
Journal Article