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Experimental Eye Research, ISSN 0014-4835, 08/2014, Volume 125, pp. 193 - 202
Journal Article
Cardiovascular Diabetology, ISSN 1475-2840, 06/2013, Volume 12, Issue 1, pp. 91 - 91
Background: Diabetic patients, through incompletely understood mechanisms, endure exacerbated ischemic heart injury compared to non-diabetic patients.... 
Ischemia-reperfusion | Inflammatory | Oxidative stress | Diabetes | Intermedin | Apoptosis | NADPH OXIDASE | ISCHEMIA/REPERFUSION INJURY | METABOLIC SYNDROME | CARDIAC & CARDIOVASCULAR SYSTEMS | NITRIC-OXIDE SYNTHASE | CARDIAC DYSFUNCTION | ACUTE CORONARY SYNDROME | INFARCT SIZE | SIGNALING PATHWAY | ENDOCRINOLOGY & METABOLISM | CARDIOVASCULAR-DISEASE | Diabetes Mellitus, Experimental - drug therapy | Diabetic Cardiomyopathies - metabolism | Apoptosis - drug effects | Streptozocin | Male | Adrenomedullin - pharmacology | Diabetic Cardiomyopathies - physiopathology | Myocardial Reperfusion Injury - pathology | Time Factors | Myocardial Infarction - pathology | Neuropeptides - pharmacology | Inflammation Mediators - metabolism | Diabetic Cardiomyopathies - prevention & control | Myocardial Infarction - physiopathology | Diabetes Mellitus, Experimental - chemically induced | Diabetes Mellitus, Experimental - metabolism | Diabetes Mellitus, Experimental - physiopathology | Cytokines - metabolism | Ventricular Function, Left - drug effects | Neuropeptides - metabolism | Adrenomedullin - metabolism | Cardiotonic Agents - pharmacology | Myocardial Infarction - metabolism | Rats, Sprague-Dawley | Myocardial Reperfusion Injury - physiopathology | Myocardial Reperfusion Injury - metabolism | Myocytes, Cardiac - pathology | Animals | Myocytes, Cardiac - drug effects | Diabetes Mellitus, Experimental - pathology | Myocytes, Cardiac - metabolism | Diabetic Cardiomyopathies - pathology | Myocardial Infarction - prevention & control | Oxidative Stress - drug effects | Myocardial Reperfusion Injury - prevention & control | Proteins | Hyperglycemia | Heart attacks | Mortality | Nitric oxide | Rodents | Cardiovascular disease
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 2, p. e16556
Berberine (BBR) is a compound originally identified in a Chinese herbal medicine Huanglian (Coptis chinensis French). It improves glucose metabolism in type 2... 
ACTIVATED PROTEIN-KINASE | MECHANISM DISTINCT | INSULIN-RESISTANCE | MUSCLE ATROPHY | LIVER | BIOLOGY | CARBOHYDRATE | ELEMENT-BINDING PROTEIN | FOXO TRANSCRIPTION FACTORS | LIPID HOMEOSTASIS | EXPRESSION | Diabetes Mellitus, Experimental - drug therapy | Streptozocin | Gluconeogenesis - drug effects | Male | Diabetes Mellitus, Type 2 - metabolism | Insulin - blood | Diabetes Mellitus, Experimental - blood | Liver - drug effects | Diabetes Mellitus, Experimental - chemically induced | Diabetes Mellitus, Experimental - metabolism | Drug Evaluation, Preclinical | Hypoglycemic Agents - therapeutic use | Blood Glucose - analysis | Liver - metabolism | Rats | Down-Regulation - drug effects | Rats, Sprague-Dawley | Hypoglycemic Agents - pharmacology | Blood Glucose - drug effects | Berberine - pharmacology | Diabetes Mellitus, Type 2 - blood | Insulin - metabolism | Animals | Glucose - metabolism | Berberine - therapeutic use | Diabetes Mellitus, Type 2 - chemically induced | Blood Glucose - metabolism | Diabetes Mellitus, Type 2 - drug therapy | Type 2 diabetes | Phosphatases | Blood sugar | Genes | DNA binding proteins | Muscle proteins | Fatty acids | Insulin | Glucose metabolism | Synthesis | Adenylic acid | Protein kinases | Adenosine triphosphate | Protein binding | Transcription factors | Peptides | Liver | Glucose | Blood | Proteins | Signal transduction | Mitochondria | Hyperglycemia | Forkhead protein | Inhibition | Drug dosages | Gluconeogenesis | Binding | Carbohydrates | Berberine | AMP | Metabolism | Fatty-acid synthase | Hepatocytes | Protein synthesis | Glucose-6-phosphatase | Endocrinology | Biomedical research | Kinases | High fat diet | Fatty liver | FOXO1 protein | Rodents | Statins | Fasting | Adenosine monophosphate | Diabetes mellitus | Oxygen consumption | Steatosis | Herbal medicine | Musculoskeletal system | Signaling | Protein kinase | Adenosine kinase | Coronary vessels | Insulin resistance | Diabetes | Respiration | Laboratory animals | ATP
Journal Article
Effect of Azadirachta indica   leaf extract on serum lipid profile changes in normal and streptozotocin induced diabetic rats, 12/2005
Effects of Azadirachta indica   leaf extract on serum lipid profile changes in normal and streptozotocin - induced diabetic rats have been studied with a view... 
cardiovascular disease | Streptozotocin induced diabetes | Serum lipid profiles | Azadirachta indica
Journal
Toxicology and Applied Pharmacology, ISSN 0041-008X, 02/2015, Volume 282, Issue 3, pp. 297 - 310
The phytochemical, curcumin, has been reported to play many beneficial roles. However, under diabetic conditions, the detail mechanism of its beneficial action... 
Oxidative and endoplasmic reticulum (ER) stress | Inflammation | Curcumin | ER/mitochondrial dependent and independent apoptosis | Diabetes | Antioxidant | ACTIVATED PROTEIN-KINASE | D-SACCHARIC ACID-1,4-LACTONE | BETA-CELLS | GLUCOSE-TRANSPORT | SIGNALING PATHWAY | INDUCED OXIDATIVE STRESS | PROTECTIVE ROLE | IN-VIVO | PHARMACOLOGY & PHARMACY | TOXICOLOGY | STREPTOZOTOCIN | NF-KAPPA-B | Diabetes Mellitus, Experimental - drug therapy | Rats, Wistar | Apoptosis - drug effects | Male | NF-kappa B - metabolism | Insulin - blood | Glucose Transporter Type 2 - metabolism | Diabetes Mellitus, Experimental - blood | Anti-Inflammatory Agents - therapeutic use | Diabetes Mellitus, Experimental - metabolism | Heme Oxygenase (Decyclizing) - metabolism | Cytokines - blood | Hypoglycemic Agents - therapeutic use | Cell Survival - drug effects | Blood Glucose - analysis | Curcumin - therapeutic use | Cytokines - metabolism | Anti-Inflammatory Agents - pharmacology | Curcumin - pharmacology | Pancreas - drug effects | Pancreas - pathology | Antioxidants - pharmacology | Pancreas - metabolism | Hypoglycemic Agents - pharmacology | Antioxidants - therapeutic use | Animals | NF-E2-Related Factor 2 - metabolism | Oxidative Stress - drug effects | Nitric Oxide - metabolism | Nitric Oxide Synthase Type II - metabolism | Glucose metabolism | Pancreatic beta cells | Blood sugar | Apoptosis | Index Medicus | APOPTOSIS | CURCUMIN | MATERIALS RECOVERY | MITOCHONDRIA | RIBOSE | PANCREAS | RATS | 60 APPLIED LIFE SCIENCES | STRESSES | INSULIN | LYMPHOKINES | GLUCOSE | INFLAMMATION | DIABETES MELLITUS
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2016, Volume 11, Issue 1, p. e0146438
Purpose We evaluated whether orally administered astaxanthin (AST) protects against oxidative damage in the ocular tissues of streptozotocin (STZ)-induced... 
BETA-CAROTENE | IN-VITRO | HUMAN-DISEASE | DB/DB MICE | VITREOUS FLUID | MULTIDISCIPLINARY SCIENCES | EXPERIMENTAL GALACTOSEMIA | HUMAN HEALTH | HEME OXYGENASE-1 | ENDOTOXIN-INDUCED UVEITIS | NF-KAPPA-B | Retina - drug effects | Gene Expression Regulation, Enzymologic - drug effects | Diabetes Mellitus, Experimental - drug therapy | Retina - metabolism | Body Weight | NF-kappa B - metabolism | Retinal Ganglion Cells - metabolism | Aqueous Humor - metabolism | Inflammation Mediators - metabolism | Female | Chemokine CCL2 - metabolism | Diabetes Mellitus, Experimental - metabolism | Electroretinography | Gene Expression | Protective Agents | RNA, Messenger - genetics | Rats | Blood Glucose | Antioxidants - pharmacology | Intercellular Adhesion Molecule-1 - metabolism | Animals | NF-kappa B - genetics | Xanthophylls - pharmacology | Oxidative Stress - drug effects | Lutein - pharmacology | Retina - pathology | Retinal Ganglion Cells - drug effects | Complications and side effects | Oxidative stress | Streptozocin | Astaxanthin | Dosage and administration | Research | Drug therapy | Immunohistochemistry | Neuroprotection | Diabetic retinopathy | Pathogenesis | Retina | Proteins | Antioxidants | Acrolein | Carotenoids | Animal tissues | Heme | Cell adhesion | Fractalkine | Drug dosages | Enzyme-linked immunosorbent assay | NF-κB protein | Damage assessment | Cytokines | Intercellular adhesion molecule 1 | Diabetes mellitus | Oral administration | Lutein | Heme oxygenase (decyclizing) | Inflammation | Metabolism | Gene expression | Medicine | Polymerase chain reaction | Oxygenase | Hospitals | Deoxyguanosine | Monocyte chemoattractant protein | Electrophoretic mobility | Nitrotyrosine | Diabetes | Monocyte chemoattractant protein 1
Journal Article
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2012, Volume 7, Issue 3, p. e33491