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Hepatology, ISSN 0270-9139, 04/2015, Volume 61, Issue 4, pp. 1332 - 1342
The mechanism of idiosyncratic drug‐induced liver injury (IDILI) remains poorly understood, to a large degree because of the lack of a valid animal model.... 
GENOME-WIDE | ADVERSE DRUG-REACTIONS | GASTROENTEROLOGY & HEPATOLOGY | SERIOUS HEPATOTOXICITY | Animals | Mice, Inbred C57BL | Amodiaquine - adverse effects | Female | Antibodies - adverse effects | Mice | CTLA-4 Antigen - immunology | Chemical and Drug Induced Liver Injury - etiology | Disease Models, Animal | Medical research | Liver | Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 02/2015, Volume 125, Issue 2, pp. 539 - 550
In contrast to microbially triggered inflammation, mechanisms promoting sterile inflammation remain poorly understood. Damage-associated molecular patterns... 
MEDICINE, RESEARCH & EXPERIMENTAL | DANGER SIGNALS | STERILE INFLAMMATION | CHROMATIN PROTEIN HMGB1 | IN-VIVO | SEPTIC SHOCK | MOBILITY GROUP BOX-1 | RECEPTOR | DEFICIENT MICE | CELL-DEATH | TRANSGENIC MICE | Acetaminophen - adverse effects | Inflammation - chemically induced | Leukocyte Elastase - metabolism | Tumor Necrosis Factor-alpha - metabolism | Inflammation - pathology | Tumor Necrosis Factor-alpha - genetics | Analgesics, Non-Narcotic - pharmacology | Hepatocytes - pathology | Hepatocytes - metabolism | Neutrophil Infiltration | fas Receptor - metabolism | Necrosis - pathology | HMGB1 Protein - genetics | Shock, Septic - metabolism | Inflammation - metabolism | Acetaminophen - pharmacology | Analgesics, Non-Narcotic - adverse effects | HMGB1 Protein - metabolism | fas Receptor - genetics | Chemical and Drug Induced Liver Injury - pathology | Neutrophils - metabolism | Receptor for Advanced Glycation End Products | Neutrophils - pathology | Shock, Septic - genetics | Shock, Septic - pathology | Lipopolysaccharides - toxicity | Macrophages - pathology | Shock, Septic - chemically induced | Leukocyte Elastase - genetics | Necrosis - metabolism | Chemical and Drug Induced Liver Injury - genetics | Mice, Knockout | Necrosis - chemically induced | Macrophages - metabolism | Animals | Chemical and Drug Induced Liver Injury - metabolism | Inflammation - genetics | Mice | Necrosis - genetics | Receptors, Immunologic - genetics | Receptors, Immunologic - metabolism | Physiological aspects | Causes of | Inflammation | Genetic aspects | Cell death | Necrosis | Chromosomal proteins | Mass spectrometry | Analysis | Proteins | Studies | Rodents | Mortality | Gangrene | Homeostasis | Mitochondrial DNA | Laboratory animals | Deoxyribonucleic acid--DNA | Apoptosis | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 2012, Volume 122, Issue 2, pp. 693 - 710
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 09/2011, Volume 118, Issue 6, pp. 1032 - 1042
Mild traumatic brain injury (mTBI) patients do not show clear structural brain defects and, in general, do not require hospitalization, but frequently suffer... 
thiothalidomide | traumatic brain injury | thalidomide | neuroinflammation | TNF‐α | etanercept | TNF-α | CELL-DEATH MECHANISMS | TNF-alpha | INFLAMMATORY DISEASES | BIOCHEMISTRY & MOLECULAR BIOLOGY | FACTOR RECEPTORS | NEUROSCIENCES | NEURODEGENERATIVE DISEASES | CLOSED-HEAD INJURY | MESSENGER-RNA | SPINAL-CORD-INJURY | RAT-BRAIN | COGNITIVE DEFICITS | Brain Chemistry - drug effects | Inflammation - chemically induced | Cell Line | Inflammation - pathology | Lipopolysaccharides - toxicity | Brain Injuries - drug therapy | Behavior, Animal - physiology | Male | Lipopolysaccharides - antagonists & inhibitors | Mice, Inbred ICR | Thalidomide - analogs & derivatives | Animals | Maze Learning | Recognition (Psychology) - drug effects | Behavior, Animal - drug effects | Avoidance Learning - drug effects | Inflammation - prevention & control | Mice | Thalidomide - therapeutic use | Brain Injuries - psychology | Tumor Necrosis Factor-alpha - biosynthesis | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Memory - physiology | Index Medicus | Drugs | Emotional behavior | Neuroprotection | Animal models | Head | Traumatic brain injury | Cytokines | Cognitive ability | Inflammation | Pattern recognition | Brain injury | Tumor necrosis factor- alpha | Mild traumatic brain injury | tumor necrosis factor-α | infliximab | head injury | interleukin-1β
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2018, Volume 13, Issue 10, pp. e0206389 - e0206389
Journal Article
Clinical Gastroenterology and Hepatology, ISSN 1542-3565, 2016, Volume 14, Issue 6, pp. 809 - 815.e1
Journal Article
Journal Article
Journal of Clinical Anesthesia, ISSN 0952-8180, 12/2017, Volume 43, pp. 77 - 83
Study objective To determine the appropriate mean arterial pressure (MAP) control level for elderly patients with hypertension during the perioperative period.... 
Mean arterial pressure | Chronic hypertension | Elderly patients | Acute kidney injury | Risk factors | MORTALITY | VARIABILITY | INTRAVENOUS FLUID | NONCARDIAC SURGERY | CARDIAC-SURGERY | ANESTHESIOLOGY | OUTCOMES | ASSOCIATION | MEAN ARTERIAL-PRESSURE | INTRAOPERATIVE HYPOTENSION | Anesthesia - methods | Postoperative Complications - etiology | Prospective Studies | Age Factors | Humans | Postoperative Complications - prevention & control | Hypertension - drug therapy | Intensive Care Units - statistics & numerical data | Male | Incidence | Arterial Pressure - drug effects | Aged, 80 and over | Hypotension - prevention & control | Monitoring, Intraoperative - methods | Female | Hypertension - diagnosis | Acute Kidney Injury - etiology | Vasoconstrictor Agents - adverse effects | Risk Factors | Anesthesia - adverse effects | Postoperative Complications - epidemiology | China - epidemiology | Digestive System Surgical Procedures - adverse effects | Random Allocation | Antihypertensive Agents - therapeutic use | Hypotension - chemically induced | Acute Kidney Injury - prevention & control | Blood Pressure Determination - methods | Hypotension - complications | Perioperative Period | Aged | Acute Kidney Injury - epidemiology | Chronic Disease | Hypertension | Medical research | Mortality | Medicine, Experimental | Aged patients | Blood pressure | Health aspects | Intensive care | Ultrasonic imaging | Kidneys | Anesthesia | Laparoscopy | Gastrointestinal surgery | Anesthesiology | Index Medicus
Journal Article
MEDICINE, ISSN 0025-7974, 12/2017, Volume 96, Issue 49, pp. e8749 - e8749
Journal Article