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1. Full Text Systemic Inflammatory Response Syndrome Criteria in Defining Severe Sepsis
by Kaukonen, Kirsi-Maija and Bailey, Michael and Pilcher, David and Cooper, D. Jamie and Bellomo, Rinaldo
The New England Journal of Medicine, ISSN 0028-4793, 04/2015, Volume 372, Issue 17, pp. 1629 - 1638
Sepsis remains a major global cause of morbidity and death. This investigation from Australia and New Zealand ICUs challenges the utility of the two criteria... 
MORTALITY | SIRS | MEDICINE, GENERAL & INTERNAL | AUSTRALIA | THERAPY | SEPTIC SHOCK | ADULTS | NEW-ZEALAND RISK | TIME | GOAL-DIRECTED RESUSCITATION | PREDICTION | Severity of Illness Index | Intensive Care Units | Humans | Middle Aged | Sepsis - diagnosis | Male | Sepsis - classification | Sepsis - mortality | Multiple Organ Failure | New Zealand | Sensitivity and Specificity | Female | Organ Dysfunction Scores | Aged | Retrospective Studies | Australia | Odds Ratio | Systemic Inflammatory Response Syndrome - classification | Systemic Inflammatory Response Syndrome - diagnosis | Systemic Inflammatory Response Syndrome - mortality | Databases, Factual | Intensive care units | Validity | Intensive care | Mortality | Sepsis | Infections | Inflammation | Inflammatory diseases | Validation studies | Index Medicus | Abridged Index Medicus
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2. Full Text RIP Kinase-Dependent Necrosis Drives Lethal Systemic Inflammatory Response Syndrome
by Duprez, Linde and Takahashi, Nozomi and Van Hauwermeiren, Filip and Vandendriessche, Benjamin and Goossens, Vera and Vanden Berghe, Tom and Declercq, Wim and Libert, Claude and Cauwels, Anje and Vandenabeele, Peter
Immunity, ISSN 1074-7613, 2011, Volume 35, Issue 6, pp. 908 - 918
Engagement of tumor necrosis factor receptor 1 signals two diametrically opposed pathways: survival-inflammation and cell death. An additional switch decides,... 
APOPTOSIS | SHOCK | ACTIVATION | NECROPTOSIS | CECAL LIGATION | CASPASES | RECEPTOR | SEPSIS | IMMUNOLOGY | TNF | CELL-DEATH | Intestines - drug effects | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Apoptosis - drug effects | Imidazoles - administration & dosage | Intestines - metabolism | Systemic Inflammatory Response Syndrome - genetics | Indoles - administration & dosage | Necrosis | Caspases - metabolism | Gene Deletion | Cecal Diseases - pathology | Indoles - pharmacology | Intestines - pathology | Mice, Inbred C57BL | Kaplan-Meier Estimate | Cecal Diseases - genetics | Imidazoles - pharmacology | Mice, Knockout | Tumor Necrosis Factor-alpha - pharmacology | Receptor-Interacting Protein Serine-Threonine Kinases - genetics | Animals | Systemic Inflammatory Response Syndrome - enzymology | Mice | Receptor-Interacting Protein Serine-Threonine Kinases - deficiency | Systemic Inflammatory Response Syndrome - mortality | Cell death | Plasma | Statistical analysis | Histopathology | Body temperature | Sepsis | Kinases | Experiments | Variance analysis | Apoptosis | Cecum | Mortality | Inflammation | Caspase-3 | tumor necrosis factor receptor 1 | Caspase-1 | Index Medicus
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3. Full Text Systemic Inflammatory Response Syndrome, Quick Sequential Organ Function Assessment, and Organ Dysfunction: Insights From a Prospective Database of ED Patients With Infection
by Williams, Julian M and Greenslade, Jaimi H and McKenzie, Juliet V and Chu, Kevin and Brown, Anthony F.T and Lipman, Jeffrey
Chest, ISSN 0012-3692, 03/2017, Volume 151, Issue 3, pp. 586 - 596
Background A proposed revision of sepsis definitions has abandoned the systemic inflammatory response syndrome (SIRS), defined organ dysfunction as an increase... 
SIRS | infection | emergency medicine | qSOFA | organ dysfunction | MORTALITY | CRITERIA | FAILURE | DEFINITIONS | RESPIRATORY SYSTEM | EMERGENCY-DEPARTMENT PATIENTS | ASSOCIATION | SEVERE SEPSIS | CRITICAL CARE MEDICINE | Emergency Service, Hospital | Prognosis | Prospective Studies | Humans | Middle Aged | Mortality | Sepsis - epidemiology | Sepsis - diagnosis | Male | Hospitalization | Systemic Inflammatory Response Syndrome - epidemiology | Multiple Organ Failure - diagnosis | Multiple Organ Failure - epidemiology | Sepsis - mortality | Sensitivity and Specificity | Aged, 80 and over | Adult | Female | Organ Dysfunction Scores | ROC Curve | Aged | Systemic Inflammatory Response Syndrome - diagnosis | Databases, Factual | Infection | Prevention | Multiple organ failure | Sepsis | Research | Risk factors | Index Medicus | Abridged Index Medicus
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4. Full Text Incidence and prognostic value of the systemic inflammatory response syndrome and organ dysfunctions in ward patients
by Churpek, Matthew M and Zadravecz, Frank J and Winslow, Christopher and Howell, Michael D and Edelson, Dana P
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 10/2015, Volume 192, Issue 8, pp. 958 - 964
Rationale: Tools that screen inpatients for sepsis use the systemic inflammatory response syndrome (SIRS) criteria and organ dysfunctions, but most studies of... 
Organ dysfunction scores | Multiple organ failure | Sepsis | Systemic inflammatory response syndrome | MORTALITY | EARLY WARNING SCORE | RISK | multiple organ failure | DEFINITIONS | systemic inflammatory response syndrome | ADMISSION | INTENSIVE-CARE-UNIT | RESPIRATORY SYSTEM | organ dysfunction scores | EARLY SEPTIC SHOCK | INFECTION | sepsis | EPIDEMIOLOGY | SEVERE SEPSIS | CRITICAL CARE MEDICINE | Prognosis | Humans | Middle Aged | Sepsis - diagnosis | Male | Incidence | Multiple Organ Failure - epidemiology | Aged, 80 and over | Adult | Female | Leukocyte Count | Databases, Factual | Patients' Rooms | Length of Stay | Heart Rate | Respiratory Rate | Hospital Mortality | Hospitalization | Body Temperature | Systemic Inflammatory Response Syndrome - epidemiology | Multiple Organ Failure - diagnosis | Mass Screening | Platelet Count | Aged | Systemic Inflammatory Response Syndrome - diagnosis | Index Medicus | Abridged Index Medicus | Original
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5. Full Text The fetal inflammatory response syndrome
by Gomez, Ricardo and Romero, Roberto and Ghezzi, Fabio and Yoon, Bo Hyun and Mazor, Moshe and Berry, Stanley M
American Journal of Obstetrics and Gynecology, ISSN 0002-9378, 1998, Volume 179, Issue 1, pp. 194 - 202
The objective of this study was to determine the frequency and clinical significance of a systemic inflammatory response as defined by an elevated plasma... 
Preterm labor | inflammatory response | intrauterine infection | neonatal morbidity | fetal homeostasis | Neonatal morbidity | Fetal homeostasis | Inflammatory response | Intrauterine infection | BIOPHYSICAL PROFILE | preterm labor | INTRAAMNIOTIC INFECTION | INTERLEUKIN-6 | OBSTETRICS & GYNECOLOGY | BLOOD-CELL COUNT | UMBILICAL-CORD | GRAM STAIN | GLUCOSE | PRETERM PREMATURE RUPTURE | LABOR | INTACT MEMBRANES | Amniocentesis | Chorioamnionitis - blood | Prevalence | Fetal Membranes, Premature Rupture - etiology | Chorioamnionitis - epidemiology | Fetal Diseases - etiology | Humans | Risk Factors | Cordocentesis | Fetal Membranes, Premature Rupture - blood | Logistic Models | Fetal Blood - metabolism | Pregnancy | Chorioamnionitis - complications | Interleukin-6 - blood | Obstetric Labor, Premature - blood | Acute-Phase Reaction - blood | Adult | Female | ROC Curve | Obstetric Labor, Premature - etiology | Infant, Newborn | Infants (Newborn) | Pneumonia | Interleukins | Analysis | Bacterial pneumonia | Prevalence studies (Epidemiology) | Measurement | Premature birth | Physiological aspects | Fetus | Inflammation | Health aspects | Interleukin-6 | Index Medicus | Abridged Index Medicus
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6. Full Text Quick sepsis-related organ failure assessment, systemic inflammatory response syndrome, and early warning scores for detecting clinical deterioration in infected patients outside theintensive care unit
by Churpek, Matthew M and Snyder, Ashley and Han, Xuan and Sokol, Sarah and Pettit, Natasha and Howell, Michael D and Edelson, Dana P
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 04/2017, Volume 195, Issue 7, pp. 906 - 911
Sepsis | Early warning scores | Systemic inflammatory response syndrome | QSOFA | Organ dysfunction Scores
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7. Full Text Quick Sepsis-related Organ Failure Assessment; Systemic Inflammatory Response Syndrome, and Early Warning Scores for Detecting Clinical Deterioration in Infected Patients outside the Intensive Care Unit
by Churpek, MM and Snyder, A and Han, X and Sokol, S and Pettit, N and Howell, MD and Edelson, DP
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, ISSN 1073-449X, 04/2017, Volume 195, Issue 7, pp. 906 - 911
Rationale: The 2016 definitions of sepsis included the quick Sepsis related Organ Failure Assessment (qSOFA) score to identify high risk patients outside the... 
CRITERIA | HOSPITALIZED-PATIENTS | INTERNATIONAL CONSENSUS DEFINITIONS | RISK STRATIFICATION | GUIDELINES | VALIDATION | PREDICTION | early warning scores | WARD PATIENTS | systemic inflammatory response syndrome | JUDGMENT | SEPTIC SHOCK SEPSIS-3 | RESPIRATORY SYSTEM | organ dysfunction scores | qSOFA | sepsis | CRITICAL CARE MEDICINE | Emergency Service, Hospital | Reproducibility of Results | Risk Assessment | Humans | Middle Aged | Sepsis - diagnosis | Male | Sepsis - complications | Hospitalization | Sensitivity and Specificity | Female | Organ Dysfunction Scores | ROC Curve | Systemic Inflammatory Response Syndrome - complications | Systemic Inflammatory Response Syndrome - diagnosis | Index Medicus | Abridged Index Medicus | Original
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8. Full Text Dynamic Systemic Inflammatory Response Syndrome Monitoring: A reSIRSgence?
by Dellinger, R Phillip
Critical Care Medicine, ISSN 0090-3493, 12/2016, Volume 44, Issue 12, pp. 2285 - 2286
systemic inflammatory response syndrome | electronic medical records | sepsis prediction | sepsis | INFECTION | CRITICAL CARE MEDICINE | Index Medicus | Abridged Index Medicus
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9. Full Text The systemic inflammatory response syndrome in cirrhotic patients: Relationship with their in-hospital outcome
by Cazzaniga, Massimo and Dionigi, Elena and Gobbo, Giulia and Fioretti, Alessia and Monti, Valentina and Salerno, Francesco
Journal of Hepatology, ISSN 0168-8278, 2009, Volume 51, Issue 3, pp. 475 - 482
Background/Aims Some evidence suggests that the systemic inflammatory response syndrome (SIRS) contributes to the poor outcome of cirrhotic patients. We... 
Gastroenterology and Hepatology | Infection | Cirrhosis | Systemic inflammatory response syndrome | Survival | Portal hypertension | ACUTE LIVER-FAILURE | MORTALITY | DIAGNOSIS | INFECTIONS | SPONTANEOUS BACTERIAL PERITONITIS | HEPATORENAL-SYNDROME | RENAL IMPAIRMENT | TUMOR-NECROSIS-FACTOR | COAGULATION DISORDERS | DISEASE | GASTROENTEROLOGY & HEPATOLOGY | Multivariate Analysis | Liver Cirrhosis - diagnosis | Liver Failure - physiopathology | Prognosis | Prospective Studies | Follow-Up Studies | Hospital Mortality | Liver Cirrhosis - complications | Systemic Inflammatory Response Syndrome - physiopathology | Humans | Middle Aged | Male | Sepsis - physiopathology | Bilirubin - blood | Creatinine - blood | Female | Aged | Systemic Inflammatory Response Syndrome - complications | Liver Cirrhosis - physiopathology | Multiple Organ Failure - physiopathology | Systemic Inflammatory Response Syndrome - diagnosis | Cohort Studies | Hypertension | Liver cancer | Liver cirrhosis | Patient outcomes | Index Medicus
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10. Full Text Postoperative pneumonia after esophagectomy and systemic inflammatory response syndrome
by Asaka, Shinichi and Shimakawa, Takeshi and Yamaguchi, Kentaro and Katsube, Takao and Usui, Takebumi and Yokomizo, Hajime and Shiozawa, Shunichi and Naritaka, Yoshihiko
Anticancer Research, ISSN 0250-7005, 02/2019, Volume 39, Issue 2, pp. 979 - 985
Background/Aim: The aim of this study was to determine the association between post-esophagectomy pneumonia and the presence of pathogenic organisms in the... 
Esophagectomy | Postoperative pneumonia | Systemic inflammatory response syndrome | DENTAL PLAQUE | esophagectomy | CYTOKINE LEVELS | RISK | COLONIZATION | CANCER | systemic inflammatory response syndrome | IMPACT | MORBIDITY | ONCOLOGY | PULMONARY COMPLICATIONS | RESPIRATORY PATHOGENS | Pneumonia | Sputum | Sepsis | Inflammatory response | Organisms | Inflammation | Pharynx | Esophagus | Index Medicus
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11. Full Text Systemic inflammatory response syndrome in Sepsis-3: A retrospective study
by Zhang, Wei and Zheng, Yan and Feng, Xiaoting and Chen, Miao and Kang, Yan
BMC Infectious Diseases, ISSN 1471-2334, 02/2019, Volume 19, Issue 1, pp. 139 - 139
BackgroundIn the new Sepsis-3 definition, sepsis is defined as life-threatening organ dysfunction due to a dysregulated host response to infection. We tested... 
Systematic inflammatory response syndrome | Sepsis | Sequential (sepsis-related) organ failure assessment | Intensive care unit | Critically ill patients | CRITICAL-CARE MEDICINE | INFECTIOUS DISEASES | INTERNATIONAL CONSENSUS DEFINITIONS | AMERICAN-COLLEGE | ORGAN FAILURE | SOCIETY | CLINICAL-CRITERIA | SEPTIC SHOCK | Predictive Value of Tests | Humans | Middle Aged | Sepsis - diagnosis | Male | Shock, Septic - diagnosis | Shock, Septic - immunology | China | Systemic Inflammatory Response Syndrome - immunology | Adult | Female | Retrospective Studies | Intensive Care Units | Sepsis - immunology | Hospital Mortality | Risk Factors | Hospitals, University | Hospitalization | Shock, Septic - mortality | Sepsis - mortality | Organ Dysfunction Scores | ROC Curve | Aged | Electronic Health Records | Systemic Inflammatory Response Syndrome - diagnosis | Systemic Inflammatory Response Syndrome - mortality | Cohort Studies | Inflammatory bowel diseases | Care and treatment | Patient outcomes | Risk factors | Intensive care | Pathogenesis | Multiple organ dysfunction syndrome | Mortality | Industrialized nations | Critical care | Septic shock | Inflammatory response | Infections | Inflammation | Criteria | Patients | Electronic medical records | Developing countries--LDCs | Medicine | Confidence intervals | Studies | Validity | Hospitals | Antibiotics | Electronic health records | Index Medicus
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12. Full Text Innate Immune Functions of Immature Neutrophils in Patients With Sepsis and Severe Systemic Inflammatory Response Syndrome
by Drifte, Geneviève and Dunn-Siegrist, Irène and Tissières, Pierre and Pugin, Jérôme
Critical Care Medicine, ISSN 0090-3493, 03/2013, Volume 41, Issue 3, pp. 820 - 832
OBJECTIVE:A hallmark of sepsis and severe systemic inflammatory response syndrome (SIRS) is the massive recruitment of immature neutrophils from the bone... 
Toll-like receptors | Sepsis | Cytokines | Chemotaxis | Phagocytosis | Neutrophils | phagocytosis | APOPTOSIS | COLONY-STIMULATING FACTOR | BONE-MARROW | MONOCLONAL-ANTIBODY 31D8 | ORGAN FAILURE | CIRCULATING NEUTROPHILS | INJURED PATIENTS | SEPTIC SHOCK | SOLUBLE MD-2 | cytokines | STAPHYLOCOCCUS-AUREUS | neutrophils | sepsis | chemotaxis | CRITICAL CARE MEDICINE | Tumor Necrosis Factor-alpha - metabolism | Neutrophils - cytology | Intensive Care Units | Sepsis - immunology | Prospective Studies | Reactive Oxygen Species - metabolism | Humans | Middle Aged | Toll-Like Receptors - immunology | Neutrophils - immunology | Phagocytosis - immunology | Male | Sepsis - complications | Immunity, Innate | Blood Bactericidal Activity | Systemic Inflammatory Response Syndrome - immunology | Aged, 80 and over | Female | Aged | Chemotaxis, Leukocyte - immunology | Cytokines - blood | Index Medicus | Abridged Index Medicus
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13. Full Text The Systemic Inflammatory Response Syndrome in Acute Liver Failure
by Rolando, Nancy and Wade, Jim and Davalos, Milagros and Wendon, Julia and Philpott-Howard, John and Williams, Roger
Hepatology, ISSN 0270-9139, 10/2000, Volume 32, Issue 4, pp. 734 - 739
The systemic inflammatory response syndrome (SIRS) in acute liver failure (ALF), in which infection is common, has not been studied. In this study, SIRS... 
PATHOGENESIS | CELLS | TUMOR-NECROSIS-FACTOR | DISEASE | SEPTIC SHOCK | SERUM | BACTERIAL-INFECTION | SEPSIS | FULMINANT HEPATIC-FAILURE | GASTROENTEROLOGY & HEPATOLOGY | TRANSPLANTATION | Anti-Bacterial Agents - therapeutic use | Liver Failure, Acute - complications | Liver Transplantation | Acetaminophen - poisoning | Humans | Systemic Inflammatory Response Syndrome - etiology | Hepatic Encephalopathy - complications | Systemic Inflammatory Response Syndrome - drug therapy | Tumor Necrosis Factor-alpha - biosynthesis | Systemic Inflammatory Response Syndrome - mortality | Index Medicus
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14. Full Text Renal systems biology of patients with systemic inflammatory response syndrome
by Tsalik, Ephraim L and Willig, Laurel K and Rice, Brandon J and van Velkinburgh, Jennifer C and Mohney, Robert P and McDunn, Jonathan E and Dinwiddie, Darrell L and Miller, Neil A and Mayer, Eric S and Glickman, Seth W and Jaehne, Anja K and Glew, Robert H and Sopori, Mohan L and Otero, Ronny M and Harrod, Kevin S and Cairns, Charles B and Fowler, Vance G and Rivers, Emanuel P and Woods, Christopher W and Kingsmore, Stephen F and Langley, Raymond J
Kidney International, ISSN 0085-2538, 10/2015, Volume 88, Issue 4, pp. 804 - 814
A systems biology approach was used to comprehensively examine the impact of renal disease and hemodialysis (HD) on patient response during critical illness.... 
hemodialysis | chronic kidney disease | acute kidney injury | gene expression | sepsis | OXIDATIVE STRESS | ENDOTHELIAL DYSFUNCTION | FALSE DISCOVERY RATES | BOUND UREMIC TOXINS | DANGER SIGNAL | EMERGENCY-DEPARTMENT | DISEASE | UROLOGY & NEPHROLOGY | URIC-ACID | T-CELLS | Metabolomics | United States | Humans | Middle Aged | Critical Illness | Male | Acute Kidney Injury - genetics | Gene Expression Profiling | Blood Proteins - metabolism | S