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Circulation Research: Journal of the American Heart Association, ISSN 0009-7330, 02/2000, Volume 86, Issue 3, pp. 255 - 263
Journal Article
Anticancer Research, ISSN 0250-7005, 10/2009, Volume 29, Issue 10, pp. 4063 - 4070
Journal Article
Molecular Cell, ISSN 1097-2765, 11/2016, Volume 64, Issue 4, pp. 803 - 814
Mitochondrial p53 is involved in apoptosis and tumor suppression. However, its regulation is not well studied. Here, we show that TRAF6 E3 ligase is a crucial... 
p53 mitochondrial translocation | tumor suppression | TRAF6 inhibits apoptosis | colorectal cancer | p300 recruitment | K63-linked ubiquitination of p53 | p53 K24 ubiquitination | genotoxic stress | MCL1/BaK | p53 transactivation | UBIQUITINATION | MDM2-DEFICIENT MICE | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | EMBRYONIC LETHALITY | DEGRADATION | BAK | NF-KAPPA-B | PROMOTES | MEMBRANE PERMEABILIZATION | CELL BIOLOGY | Neoplasm Transplantation | Colonic Neoplasms - genetics | Tumor Suppressor Protein p53 - antagonists & inhibitors | Colonic Neoplasms - drug therapy | Humans | Cytosol - drug effects | E1A-Associated p300 Protein - genetics | Gene Expression Regulation, Neoplastic | Myeloid Cell Leukemia Sequence 1 Protein - metabolism | bcl-2 Homologous Antagonist-Killer Protein - genetics | Apoptosis - genetics | Antineoplastic Agents - therapeutic use | E1A-Associated p300 Protein - metabolism | bcl-2 Homologous Antagonist-Killer Protein - metabolism | Tumor Suppressor Protein p53 - genetics | Ubiquitination | Cell Nucleus - metabolism | Lysine - metabolism | TNF Receptor-Associated Factor 6 - genetics | Colonic Neoplasms - mortality | Signal Transduction | Tumor Suppressor Protein p53 - metabolism | Mitochondria - metabolism | Mitochondria - drug effects | Sulfonamides - pharmacology | Myeloid Cell Leukemia Sequence 1 Protein - genetics | Protein Transport | Xenograft Model Antitumor Assays | Animals | Colonic Neoplasms - pathology | Survival Analysis | TNF Receptor-Associated Factor 6 - metabolism | Cell Line, Tumor | Cytosol - metabolism | Mice | Cell Nucleus - drug effects | Ubiquitin | Medical colleges | Chemotherapy | Ligases | Colorectal cancer | Tumor proteins | Drug resistance | Cancer | Apoptosis | Yuan (China) | Index Medicus
Journal Article
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 02/2010, Volume 21, Issue 2, pp. 284 - 294
The mechanism by which the serine-threonine kinase glycogen synthase kinase-3 beta (GSK3 beta) affects survival of renal epithelial cells after acute stress is... 
GLYCOGEN-SYNTHASE KINASE-3-BETA | DEPENDENT ANION CHANNEL | INHIBITS APOPTOSIS | SIGNALING PATHWAYS | TRANSITION PORE | UROLOGY & NEPHROLOGY | ACUTE TUBULAR-NECROSIS | OUTER-MEMBRANE PERMEABILIZATION | NF-KAPPA-B | CELL-DEATH | MOLECULAR-MECHANISMS | Basic Research
Journal Article
FEBS Journal, ISSN 1742-464X, 12/2015, Volume 282, Issue 24, pp. 4747 - 4765
Renal cell carcinoma ( RCC ) is resistant to traditional cancer therapies, and metastatic RCC (mRCC) is incurable. The shortcomings in current therapeutic... 
apoptosis | triptolide | renal cell carcinoma | TRAIL | death receptor | HEAT-SHOCK-PROTEIN-70 INHIBITS APOPTOSIS | DENDRITIC CELLS | (TRAIL)-INDUCED APOPTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANTI-DR5 ANTIBODY THERAPY | HEAT-SHOCK PROTEINS | TUMOR-NECROSIS-FACTOR | APOPTOSIS-INDUCING LIGAND | IN-VIVO | NF-KAPPA-B | PANCREATIC-CANCER CELLS | Recombinant Proteins - therapeutic use | Neoplasm Transplantation | Antineoplastic Combined Chemotherapy Protocols - chemistry | Apoptosis - drug effects | Receptors, TNF-Related Apoptosis-Inducing Ligand - agonists | Humans | Organophosphates - therapeutic use | Antibodies, Monoclonal - therapeutic use | Antineoplastic Agents - therapeutic use | Kidney Neoplasms - metabolism | Receptors, TNF-Related Apoptosis-Inducing Ligand - metabolism | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Epoxy Compounds - pharmacology | TNF-Related Apoptosis-Inducing Ligand - pharmacology | TNF-Related Apoptosis-Inducing Ligand - agonists | Female | Antineoplastic Agents - pharmacology | Antineoplastic Agents, Phytogenic - therapeutic use | Carcinoma, Renal Cell - drug therapy | Antibodies, Monoclonal - chemistry | Diterpenes - pharmacology | Epoxy Compounds - therapeutic use | Diterpenes - therapeutic use | Phenanthrenes - therapeutic use | Specific Pathogen-Free Organisms | Carcinoma, Renal Cell - pathology | Antibodies, Monoclonal - pharmacology | Recombinant Proteins - chemistry | Recombinant Proteins - pharmacology | Antineoplastic Agents - chemistry | TNF-Related Apoptosis-Inducing Ligand - therapeutic use | Drug Synergism | Organophosphates - pharmacology | Carcinoma, Renal Cell - metabolism | Phenanthrenes - pharmacology | Animals | Tumor Burden - drug effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Survival Analysis | Cell Line, Tumor | Kidney Neoplasms - pathology | Mice | Mice, Inbred BALB C | Prodrugs - therapeutic use | Antineoplastic Agents, Phytogenic - pharmacology | Kidney Neoplasms - drug therapy | Prodrugs - pharmacology | TNF-Related Apoptosis-Inducing Ligand - genetics | Heat shock proteins | Carcinoma, Renal cell | Rodents | Tumors | Apoptosis | Index Medicus
Journal Article
PLoS Biology, ISSN 1544-9173, 07/2010, Volume 8, Issue 7, p. e1000410
Endoplasmic reticulum (ER) stress is a feature of secretory cells and of many diseases including cancer, neurodegeneration, and diabetes. Adaptation to ER... 
CYTOCHROME-C | HEAT-SHOCK PROTEINS | INHIBITS APOPTOSIS | MESSENGER-RNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOLOGY | TRANSCRIPTION FACTOR XBP-1 | APAF-1 APOPTOSOME | ENDOPLASMIC-RETICULUM STRESS | PC12 CELLS | KINASE JNK | BCL-2 FAMILY
Journal Article
International Journal of Oncology, ISSN 1019-6439, 11/2018, Volume 53, Issue 5, pp. 2191 - 2199
Whilst the role of microRNA-143 (miR-143) in myelodysplastic syndrome (MDS) remains unclear, abnormally expressed microRNA-143 has been detected in many types... 
microRNA-143 | Xenograft | Lentivirus | Myelodysplastic syndrome | Cell apoptosis | INHIBITS GROWTH | PROLIFERATION | AUTOPHAGY | CHEMOTHERAPY | xenograft | ONCOLOGY | GASTRIC-CANCER | COLORECTAL-CANCER | DYSREGULATION | cell apoptosis | TUMOR-SUPPRESSOR | LEUKEMIA | myelodysplastic syndrome | EXPRESSION | lentivirus | Studies | Cell growth | MicroRNAs | Leukemia | Genes | Cell cycle | Infections | Cancer | Apoptosis | Index Medicus
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2011, Volume 108, Issue 22, pp. 9238 - 9243
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 07/2019, Volume 234, Issue 7, pp. 11037 - 11046
Journal Article