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2009, 1st ed., Wiley series in drug discovery and development., ISBN 0470275006, xv, 1022
The book gives students and young researchers a resource on zinc enzymes, some of which were intensively studied for more than six decades and translated into... 
Drugs | Design | chemistry | Zinc enzymes | Carbonic Anhydrase Inhibitors | Inhibitors | Drug Design | pharmacokinetics | Zinc | Therapeutic use | Drug Delivery Systems | Medical / Pharmacology | Drug Discovery & Development
Book
Cell Reports, ISSN 2211-1247, 09/2016, Volume 16, Issue 10, pp. 2576 - 2592
The mechanisms underlying Zika virus (ZIKV)-related microcephaly and other neurodevelopment defects remain poorly understood. Here, we describe the derivation... 
NEURAL PROGENITORS | LONG-TERM | HUMAN BRAIN | ADAPTER | CENTRAL-NERVOUS-SYSTEM | INFECTION | MICE | BINDING KINASE 1 | ORGANOIDS | INNATE IMMUNITY | CELL BIOLOGY | Neocortex - pathology | Neurons - pathology | Transcription, Genetic - drug effects | Brain - embryology | Neuroglia - ultrastructure | Neuroglia - pathology | Humans | Brain - virology | Centrosome - drug effects | Gene Expression Profiling | Microcephaly - virology | Neural Stem Cells - ultrastructure | Zika Virus Infection - virology | Neural Stem Cells - immunology | Neuroepithelial Cells - immunology | Neuroprotective Agents - pharmacology | Spinal Cord - pathology | Microcephaly - pathology | Neuroepithelial Cells - virology | Nucleosides - pharmacology | Fetus - virology | Cell Death - drug effects | Phosphorylation - drug effects | Neurons - drug effects | Protein-Serine-Threonine Kinases - metabolism | Zika Virus - pathogenicity | Proto-Oncogene Proteins - metabolism | Zika Virus - ultrastructure | Neurons - virology | Virus Replication - drug effects | Neuroepithelial Cells - ultrastructure | Immunity, Innate - drug effects | Zika Virus Infection - pathology | Neural Stem Cells - virology | Zika Virus - physiology | Zika Virus - drug effects | Mitochondria - metabolism | Mitochondria - drug effects | Receptor Protein-Tyrosine Kinases - metabolism | Neural Stem Cells - enzymology | Centrosome - metabolism | Mitosis - drug effects | Brain - pathology | Protein Kinase Inhibitors - pharmacology | Neuroglia - virology | Neuroepithelial Cells - drug effects | Neurons/pathology | Zika Virus/pathogenicity | Mitochondria/metabolism | Virus Replication/drug effects | Microcephaly/pathology | Neurons/drug effects | Protein-Serine-Threonine Kinases/metabolism | Neural Stem Cells/immunology | Neuroglia/ultrastructure | Neuroepithelial Cells/drug effects | Neuroepithelial Cells/virology | Life Sciences | Brain/pathology | Zika Virus/drug effects | Brain/embryology | Mitochondria/drug effects | Fetus/virology | Neocortex/pathology | Neuroglia/pathology | Cell Death/drug effects | Mitosis/drug effects | Transcription, Genetic/drug effects | Nucleosides/pharmacology | Neural Stem Cells/enzymology | Neural Stem Cells/ultrastructure | Neuroepithelial Cells/ultrastructure | Receptor Protein-Tyrosine Kinases/metabolism | Microcephaly/virology | Proto-Oncogene Proteins/metabolism | Neuroprotective Agents/pharmacology | Zika Virus/ultrastructure | Neuroepithelial Cells/immunology | Brain/virology | Immunity, Innate/drug effects | Spinal Cord/pathology | Zika Virus/physiology | Neuroglia/virology | Microbiology and Parasitology | Zika Virus Infection/pathology | Neurons/virology | Zika Virus Infection/virology | Neural Stem Cells/virology | Centrosome/drug effects | Protein Kinase Inhibitors/pharmacology | Centrosome/metabolism | Phosphorylation/drug effects
Journal Article
Advances in antiviral drug design, ISSN 1075-8593, 1993
Journal
Clinical Pharmacokinetics, ISSN 0312-5963, 1/2011, Volume 50, Issue 1, pp. 25 - 39
Etravirine (formerly TMC125) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) with activity against wild-type and NNRTI-resistant strains of HIV-1.... 
Pharmacotherapy | Internal Medicine | Medicine & Public Health | Pharmacology/Toxicology | Drug-interactions | Ribavirin, drug interactions | Antiepileptic-drugs, drug interactions | Simvastatin, drug interactions | Voriconazole, drug interactions | Dexamethasone, drug interactions | Fibric-acid-derivatives, drug interactions | Rifampicin, drug interactions | Opioid-analgesics, drug interactions | Antidepressants, drug interactions | Atorvastatin, drug interactions | Antiretrovirals, drug interactions | Anti-infectives, drug interactions | Histamine-H2-receptor-antagonists, drug interactions | Diazepam, drug interactions | Ketoconazole, drug interactions | Fluconazole, drug interactions | Hypericum, drug interactions | HMG-CoA-reductase-inhibitors, drug interactions | Oral-contraceptives, drug interactions | Sildenafil, drug interactions | Omeprazole, drug interactions | Buprenorphine, drug interactions | Rosuvastatin, drug interactions | Non-nucleoside-reverse-transcriptase-inhibitors, drug interactions | Type-5-cyclic-nucleotide- phosphodiesterase-inhibitors, drug interactions | Corticosteroids, drug interactions | Paroxetine, drug interactions | Fluoxetine, drug interactions | Rifapentine, drug interactions | Ethinylestradiolnorethisterone, drug interactions | Ranitidine, drug interactions | Etravirine, drug interactions | Antifungals, drug interactions | Digoxin, drug interactions | Warfarin, drug interactions | Methadone, drug interactions | Fluvastatin, drug interactions | Rifabutin, drug interactions | Sertraline, drug interactions | Azithromycin, drug interactions | Pharmacokinetics | Calcineurin-inhibitors, drug interactions | Itraconazole, drug interactions | Proton-pump-inhibitors, drug interactions | Clarithromycin, drug interactions | METABOLISM | EFFICACY | METHADONE | EXPERIENCED HIV-1-INFECTED PATIENTS | TMC125 ETRAVIRINE | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | HUMAN LIVER | PHARMACODYNAMICS | 2 DIFFERENT FORMULATIONS | CLINICAL PHARMACOKINETICS | Reverse Transcriptase Inhibitors - adverse effects | Reverse Transcriptase Inhibitors - pharmacokinetics | Drug Interactions | Drug-Related Side Effects and Adverse Reactions | Humans | Pyridazines - pharmacokinetics | Drug Therapy, Combination | Pyridazines - adverse effects | Etravirine | Drug interactions | Physiological aspects | Dosage and administration | Research | Properties | Drug therapy | HIV infection
Journal Article
1996, Basic and clinical oncology, ISBN 9780824793142, Volume 9., xiv, 739
Book
2006, ISBN 9780470012949, xvii, 350 p., [8] p. of plates
Book
Journal Article
2008, ISBN 9780123694485, xv, 473 p., [27] p. of plates
The ultimate source of information on the design of new anticancer agents, emphasizing small molecules, this newest work covers recent notable successes... 
Antineoplastic agents | Clinical & internal medicine | Design | Development
Book
Anti-cancer drugs, ISSN 0959-4973, 1990
Journal
Journal Article
by Zhang, L and Wu, F and Lee, S C and Zhao, H and Zhang, L
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 08/2014, Volume 96, Issue 2, pp. 266 - 277
Journal Article
The Journal of Clinical Pharmacology, ISSN 0091-2700, 08/2013, Volume 53, Issue 8, pp. 866 - 877
Brentuximab vedotin is an antibody–drug conjugate (ADC) that selectively delivers monomethyl auristatin E (MMAE) into CD30‐expressing cells. This study... 
pharmacokinetics | clinical pharmacology | biotechnology | clinical trials | oncology | drug metabolism | Clinical pharmacology | Clinical trials | Drug metabolism | Biotechnology | Oncology | Pharmacokinetics | PHASE-II | ANTITUMOR-ACTIVITY | HODGKINS-DISEASE | LYMPHOMA | PHARMACOLOGY & PHARMACY | SGN-35 | MONOCLONAL-ANTIBODIES | MIDAZOLAM | Ketoconazole - administration & dosage | Humans | Middle Aged | Immunoconjugates - pharmacokinetics | Midazolam - administration & dosage | Ki-1 Antigen - immunology | Male | Antineoplastic Agents - administration & dosage | Immunoconjugates - administration & dosage | Young Adult | Rifampin - adverse effects | Drug Interactions | Midazolam - adverse effects | Antineoplastic Agents - adverse effects | Adult | Female | Antineoplastic Agents - pharmacokinetics | Rifampin - administration & dosage | Hematologic Neoplasms - metabolism | Immunoconjugates - adverse effects | Oligopeptides - metabolism | Midazolam - pharmacokinetics | Cross-Over Studies | Cytochrome P-450 CYP3A Inhibitors | Feces - chemistry | Cytochrome P-450 CYP3A - metabolism | Adolescent | Aged | Ketoconazole - adverse effects | Complications and side effects | Brentuximab vedotin | Drug interactions | Cytochrome P-450 | Physiological aspects | Dosage and administration | Research | Blood diseases | Drug therapy | Clinical Pharmacology | Clinical Trials | Pharmacokinetics and Drug Metabolism
Journal Article