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Journal Article
Surgery, ISSN 0039-6060, 05/2019, Volume 165, Issue 5, pp. 946 - 952
The Jumonji-domain containing 3 has diverse roles in multiple cancers. Here, we investigated its prognostic significance in esophageal squamous cell carcinoma.... 
INK4A/ARF | SURGERY | ACTIVATION | HISTONE DEMETHYLASE JMJD3 | UTX | SENESCENCE | CANCER | CONTRIBUTES | Immunohistochemistry | Medical colleges | Care and treatment | Squamous cell carcinoma | Analysis | Esophageal cancer
Journal Article
BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS, ISSN 1874-9399, 03/2015, Volume 1849, Issue 3, pp. 247 - 256
Inactivation of p14(ARF) and p16(INK4A) by epigenetic changes in cutaneous and uveal melanoma has been here investigated. Compared with melanocytes, p14(ARF)... 
Human melanoma | METHYLATION ANALYSIS | PROMOTER HYPERMETHYLATION | LOW-FREQUENCY | BIOCHEMISTRY & MOLECULAR BIOLOGY | Promoter methylation | p14(ARF) | MALIGNANT-MELANOMA | Epi-drug | P53 | INACTIVATION | CIGARETTE-SMOKING | BIOPHYSICS | P16 | GROWTH ARREST | INK4A/ARF LOCUS | p16(INK4A) | Histone deacetylation
Journal Article
BMC cancer, ISSN 1471-2407, 2012, Volume 12, Issue 1, pp. 470 - 470
Background: The histone H3K27 demethylases UTX and JMJD3 are important regulatory factors that modulate gene expression by altering the physical state of... 
JMJD3 | INK4A/ARF | SUPPRESSOR | INK4A-ARF LOCUS | JMJD3 CONTRIBUTES | INDUCED SENESCENCE | CANCER | GENE | ONCOLOGY | Renal cell carcinoma | UTX | Epigenetics | Histone H3K27 demethylase | PROTEINS | Up-Regulation | Kidney Neoplasms - genetics | Polycomb Repressive Complex 2 - genetics | Histone Demethylases - biosynthesis | Cyclin-Dependent Kinase 4 - genetics | Humans | Middle Aged | Transcriptional Activation | Carcinoma, Renal Cell - genetics | Male | RNA, Messenger - metabolism | Histone Demethylases - genetics | Adult | Carcinoma, Renal Cell - enzymology | Female | Nuclear Proteins - genetics | RNA, Messenger - genetics | Cyclin-Dependent Kinase Inhibitor p16 - genetics | Nuclear Proteins - metabolism | Cyclin-Dependent Kinase 4 - metabolism | Jumonji Domain-Containing Histone Demethylases - genetics | Enhancer of Zeste Homolog 2 Protein | Histone Demethylases - metabolism | Kidney Neoplasms - enzymology | Cyclin-Dependent Kinase Inhibitor p16 - metabolism | Aged | Methylation | Polycomb Repressive Complex 2 - metabolism | Jumonji Domain-Containing Histone Demethylases - metabolism | Physiological aspects | Development and progression | Monoamine oxidase | Carcinoma, Renal cell | Research | Analysis | Epigenetic inheritance | Chromatin | RNA | Genes | Genetic research | Genetic aspects | Gene expression | Cancer | Index Medicus
Journal Article
Cellular and Molecular Life Sciences, ISSN 1420-682X, 4/2010, Volume 67, Issue 7, pp. 1165 - 1176
Journal Article
Journal Article
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, ISSN 0925-4439, 11/2008, Volume 1782, Issue 11, pp. 642 - 648
We report here that the polycomb group protein Bmi1 promotes prostate tumorigenesis. Bmi1 is detected at higher levels in androgen-independent PC3 and DU145... 
CANCER PATIENTS | METHYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | p14(ARF) | MOLECULAR MARKER | PROLIFERATION | Bmi1 | OVEREXPRESSION | BIOPHYSICS | EPITHELIAL-CELLS | GENE | CELL SELF-RENEWAL | MYC TRANSGENIC MICE | INK4A/ARF LOCUS | p16(INK4A) | Prostate cancer
Journal Article
Oncology Letters, ISSN 1792-1074, 2017, Volume 14, Issue 2, pp. 1550 - 1560
Previous studies have demonstrated abnormal H3K27 methylation status during clear cell renal cell carcinoma (ccRCC) carcinogenesis, and have suggested that the... 
Jumonji domain-containing protein 3 | Clear cell renal cell carcinoma | Overall survival | Disease free survival | Prognostic biomarker | INK4A/ARF | clear cell renal cell carcinoma | ENHANCER | jumonji domain-containing protein 3 | CANCER | RADICAL NEPHRECTOMY | ONCOLOGY | overall survival | prognostic biomarker | disease free survival | CONTRIBUTES | EZH2 | TOOL
Journal Article
Stem Cell Reports, ISSN 2213-6711, 06/2018, Volume 10, Issue 6, pp. 1721 - 1733
Brain neurogenesis is severely impaired following exposure to ionizing radiation (IR). We and others have shown that the expression of the tumor suppressor... 
senescence | neurogenesis | INK4a/ARF | DNA damage | irradiation | p53 | OXIDATIVE STRESS | CHILDHOOD-CANCER | ADULT NEUROGENESIS | HEMATOPOIETIC STEM-CELLS | ACUTE LYMPHOBLASTIC-LEUKEMIA | DNA-DAMAGE | CRANIAL IRRADIATION | IONIZING-RADIATION | HIPPOCAMPAL NEUROGENESIS | COGNITIVE DEFICITS | CELL & TISSUE ENGINEERING | CELL BIOLOGY
Journal Article
Molecular and Cellular Endocrinology, ISSN 0303-7207, 08/2013, Volume 375, Issue 1-2, pp. 35 - 42
Journal Article
Journal Article