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1. Full Text Muscle-Specific Insulin Receptor Overexpression Protects Mice From Diet-Induced Glucose Intolerance but Leads to Postreceptor Insulin Resistance
by Wang, Guoxiao and Yu, Yingying and Cai, Weikang and Batista, Thiago M and Suk, Sujin and Noh, Hye Lim and Hirshman, Michael and Nigro, Pasquale and Li, Mengyao Ella and Softic, Samir and Goodyear, Laurie and Kim, Jason K and Kahn, C. Ronald
Diabetes (New York, N.Y.), ISSN 0012-1797, 11/2020, Volume 69, Issue 11, pp. 2294 - 2309
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Obesity | Phosphorylation | Body fat | Body weight | AKT protein | Glucose | Ribonucleic acid--RNA | Insulin | Skeletal muscle | High fat diet | Glucose tolerance | Glucose metabolism | Musculoskeletal system | Intolerance | Signal transduction | Insulin receptor substrate 1 | Insulin receptors | Glycolysis | Insulin resistance | Diabetes mellitus (non-insulin dependent) | Index Medicus | Abridged Index Medicus
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2. Full Text Mutations in the Drosophila insulin receptor substrate, CHICO, impair olfactory associative learning
by Naganos, Shintaro and Horiuchi, Junjiro and Saitoe, Minoru
Neuroscience research, ISSN 0168-0102, 05/2012, Volume 73, Issue 1, pp. 49 - 55
Learning and memory | Behavior | Drosophila | Insulin receptor substrate | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Intracellular Signaling Peptides and Proteins - biosynthesis | Mutation - genetics | Substrate Specificity - genetics | Association Learning - physiology | Odorants | Drosophila Proteins - biosynthesis | Animals | Receptor, Insulin - genetics | Insulin Receptor Substrate Proteins - biosynthesis | Receptor, Insulin - metabolism | Drosophila Proteins - genetics | Insulin Receptor Substrate Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | Genetic aspects | Insulin | Memory | Shock | Brain | Mushroom bodies | Neurons | Olfactory discrimination learning | Associative learning | Nervous system | Insulin-like growth factors | Insulin receptors | Mutation | Transgenes | Odor | Index Medicus
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3. Full Text Akt signaling pathway in macrophage activation and M1/M2 polarization
by Vergadi, Eleni and Ieronymaki, Eleftheria and Lyroni, Konstantina and Vaporidi, Katerina and Tsatsanis, Christos
The Journal of immunology (1950), ISSN 0022-1767, 02/2017, Volume 198, Issue 3, pp. 1006 - 1014
Life Sciences & Biomedicine | Immunology | Science & Technology | Macrophages - physiology | Cell Polarity | Protein-Serine-Threonine Kinases - physiology | Humans | PTEN Phosphohydrolase - physiology | Proto-Oncogene Proteins c-akt - physiology | Autophagy | Macrophage Activation | Animals | Apolipoproteins E - physiology | Phosphatidylinositol 3-Kinases - physiology | Signal Transduction - physiology | TOR Serine-Threonine Kinases - physiology | Endotoxins - toxicity | Phagocytosis | TOR protein | Polarization | Serine | Cytokine receptors | AKT protein | Hormones | Macrophages | Kinases | Signal transduction | Receptors | Cell activation | Insulin receptors | AKT1 protein | Immune response | Threonine | Cytokines | RNA-mediated interference | AKT2 protein | Metabolism | Ribonucleic acid--RNA | Insulin | Disease control | 1-Phosphatidylinositol 3-kinase | Signaling | Isoforms | Index Medicus | Abridged Index Medicus
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4. Full Text Fucoxanthin promotes translocation and induction of glucose transporter 4 in skeletal muscles of diabetic/obese KK-Ay mice
by Nishikawa, Sho and Hosokawa, Masashi and Miyashita, Kazuo
Phytomedicine (Stuttgart), ISSN 0944-7113, 03/2012, Volume 19, Issue 5, pp. 389 - 394
Fucoxanthin | PGC-1α | Akt | Glucose transporter 4 | Insulin receptor | Skeletal muscle | Glucose transporter | Translocation | Obesity | Phosphorylation | Diabetes mellitus | AKT protein | mRNA | Cytosol | Insulin | soleus muscle | Diets | Signal transduction | Hyperglycemia | Insulin receptors | Plasma membranes | Peroxisome proliferator-activated receptors | PGC-1 protein
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5. Full Text Is insulin an anabolic agent in bone? Dissecting the diabetic bone for clues
by Kathryn M. Thrailkill and Charles K. Lumpkin, Jr and R. Clay Bunn and Stephen F. Kemp and John L. Fowlkes
American Journal of Physiology - Endocrinology And Metabolism, ISSN 0193-1849, 11/2005, Volume 289, Issue 5, pp. 735 - 745
Osteoporosis | Type 2 diabetes mellitus | Insulin receptors | Hyperinsulinism | Osteoblasts | Type 1 diabetes mellitus | Endocrinology & Metabolism | Physiology | Life Sciences & Biomedicine | Science & Technology | Bone and Bones - pathology | Bone Density - physiology | Insulin - physiology | Humans | Diabetes Mellitus, Type 1 - metabolism | Bone Diseases, Metabolic - pathology | Bone Remodeling - physiology | Diabetes Mellitus, Type 1 - complications | Diabetes Mellitus, Type 2 - metabolism | Osteoporosis - etiology | Bone Remodeling - drug effects | Bone and Bones - drug effects | Fractures, Bone - etiology | Osteoporosis - metabolism | Bone and Bones - metabolism | Diabetes Mellitus, Type 2 - complications | Insulin - pharmacology | Diabetes Mellitus, Type 1 - pathology | Fractures, Bone - metabolism | Bone Diseases, Metabolic - metabolism | Bone Density - drug effects | Animals | Osteoporosis - pathology | Fractures, Bone - pathology | Diabetes Mellitus, Type 2 - pathology | Index Medicus | insulin receptors | type 2 diabetes mellitus | type 1 diabetes mellitus | hyperinsulinism | osteoblasts | osteoporosis
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6. Full Text Insulin and Insulin Receptors in Adipose Tissue Development
by Cignarelli, Angelo and Genchi, Valentina Annamaria and Perrini, Sebastio and Natalicchio, Annalisa and Laviola, Luigi and Giorgino, Francesco
International journal of molecular sciences, ISSN 1422-0067, 02/2019, Volume 20, Issue 3, p. 759
adipose tissue | receptor isoform | insulin receptor | adipocyte | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Alternative splicing | Transcription factors | Adipose tissue | Body weight | Paracrine signalling | Lipids | Insulin-like growth factors | Adipocytes | Glucose | Kinases | Cell adhesion & migration | Proteins | Functional plasticity | Angiogenesis | Receptors | Insulin receptors | Physiology | Adipose tissue (brown) | Adipogenesis | Cytokines | Metabolism | Gene expression | Fatty acids | Insulin | Endothelium | Stem cells | Insulin resistance | Diabetes | Index Medicus
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7. Full Text Polymorphisms in the IRS‐1 and PPAR-γ genes and their association with polycystic ovary syndrome among South Indian women
by Dasgupta, Shilpi and Sirisha, Pisapati and Neelaveni, Kudugunti and Anuradha, Katragadda and Sudhakar, Godi and Reddy, B. Mohan
Gene, ISSN 0378-1119, 07/2012, Volume 503, Issue 1, pp. 140 - 146
PPAR‐γ | PCOS | IRS-1 | South Indian women | Polymorphism | PPAR-γ | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Body Mass Index | European Continental Ancestry Group - genetics | Hyperandrogenism - genetics | Genetic Association Studies | Exons | Gene Frequency | Humans | Middle Aged | India - epidemiology | Molecular Sequence Data | Sequence Analysis, DNA | Polymorphism, Genetic | Young Adult | Haplotypes - genetics | Base Sequence | Adolescent | Polycystic Ovary Syndrome - genetics | Adult | Female | Polymorphism, Single Nucleotide | Insulin Receptor Substrate Proteins - genetics | PPAR gamma - genetics | Index Medicus | Haplotypes | Hyperinsulinemia | Adipose tissue | Dyslipidemia | Association analysis | Single-nucleotide polymorphism | Gene polymorphism | polycystic ovary syndrome | Insulin receptor substrate 1 | Insulin receptors | Ethnic groups | Mutation | Peroxisome proliferator-activated receptors
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8. Full Text 1892-P: Meal- and Glucose-Induced Suppression of Ghrelin Release Is Mediated Primarily by Ghrelin Cell-Expressed Insulin Receptors
by SHANKAR, KRIPA and TAKEMI, SHOTA and GUPTA, DEEPALI and MANI, BHARATH K and OSBORNE-LAWRENCE, SHERRI and METZGER, NATHAN and BERGLUND, ERIC and ZIGMAN, JEFFREY M
Diabetes (New York, N.Y.), ISSN 0012-1797, 06/2020, Volume 69, Issue Supplement 1, p. 1892
Glucose tolerance | Plasma | Insulin receptors | Potassium channels (inwardly-rectifying) | Ghrelin | Food intake | Mucosa | Glucose | Diabetes | Meals | Hypoglycemia | Insulin
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9. Full Text Der Insulinrezeptor in Aktion — wie Insulin seinen Rezeptor aktiviert
by Gutmann, Theresia
Biospektrum, ISSN 0947-0867, 09/2019, Volume 25, Issue 5, pp. 485 - 487
Signal transduction | Insulin receptors | Electron microscopy | Insulin
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10. Full Text Hypoglycemic and antioxidant effect of Juniperus procera extract on rats with streptozotocin-induced diabetes
by Alkhedaide, Adel and Abdo Nassan, Mohamed and Ahmed Ismail, Tamer and Soliman, Mohamed Mohamed and Hassan Mohamed, Essam and Hassan Amer, Hamada and Aldhahrani, Adil
Pathophysiology (Amsterdam), ISSN 0928-4680, 09/2019, Volume 26, Issue 3-4, pp. 361 - 368
Antioxidants | Diabetes | Insulin receptors | Expression | Juniperus procera extract
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11. Full Text Food For Thought: Short-Term Fasting Upregulates Glucose Transporters in Neurons and Endothelial Cells, But Not in Astrocytes
by Dakic, Tamara and Dakic, Tamara and Jevdjovic, Tanja and Jevdjovic, Tanja and Lakic, Iva and Lakic, Iva and Djurasevic, Sinisa F and Djurasevic, Sinisa F and Djordjevic, Jelena and Djordjevic, Jelena and Vujovic, Predrag and Vujovic, Predrag
Neurochemical research, ISSN 0364-3190, 2/2019, Volume 44, Issue 2, pp. 388 - 399
Neurochemistry | Biochemistry, general | Neurology | Neurosciences | Biomedicine | Fasting | Glucose transporters | Rat | Glycogen | Hypothalamus | Insulin receptor | Cell Biology | Biochemistry & Molecular Biology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Proteins | Glucose metabolism | RNA | Neurons | Physiological aspects | Glucose | Insulin | Dextrose | Endothelium | Glucose transporter | Short term | Translocation | Brain | Astrocytes | Cell membranes | Metabolism | Gene expression | Metabolic response | Endothelial cells | Tanycytes | Receptors | Insulin receptors | Localization | Index Medicus
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