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MOLECULAR BIOLOGY OF THE CELL, ISSN 1059-1524, 05/2007, Volume 18, Issue 5, pp. 1634 - 1644
We have characterized early steps of alpha(2)beta(1) integrin-mediated cell adhesion to a collagen type I matrix by using single-cell force spectroscopy. In... 
STRESS FIBERS | INTEGRINS ALPHABETA | LIGAND-BINDING | MOLECULAR ADHESION | RECOGNITION | ALPHABETA | CROSS-LINKING | FIBRONECTIN | MICROSCOPY | FOCAL ADHESIONS | CELL BIOLOGY
Journal Article
JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 08/2007, Volume 50, Issue 16, pp. 3786 - 3794
Starting from the structure of integrin alpha v beta 3 in a complex with a peptidic ligand plus SAR data on nonpeptidic ligands, we derived a new class of... 
CHEMISTRY, MEDICINAL | ALPHABETA INTEGRIN | ALPHA-5-BETA-1
Journal Article
NEW ENGLAND JOURNAL OF MEDICINE, ISSN 0028-4793, 05/2011, Volume 364, Issue 20, pp. 1943 - 1954
IN 2009, THE UNITED NATIONS ESTIMATED THAT 33.2 MILLION PEOPLE worldwide were living with human immunodeficiency virus type 1 (HIV-1) infection and that 2.6... 
RESPONSES | SIV | MEDICINE, GENERAL & INTERNAL | VIREMIA | INTEGRIN ALPHABETA | PARTNER NOTIFICATION | STAGE | IMMUNODEFICIENCY-VIRUS TYPE-1 | CD4(+) T-CELLS | ANTIRETROVIRAL THERAPY | SEXUAL TRANSMISSION
Journal Article
BLOOD, ISSN 0006-4971, 06/2012, Volume 119, Issue 23, pp. 5429 - 5437
The BM microenvironment is required for the maintenance, proliferation, and mobilization of hematopoietic stem and progenitor cells (HSPCs), both during... 
PROGENITOR CELLS | III REPEAT | ALPHABETA | INTEGRIN | FIBRONECTIN | STEM-CELL NICHE | SELF-RENEWAL | PROLIFERATION | DIFFERENTIATION | IDENTIFICATION | HEMATOLOGY
Journal Article
SCIENCE, ISSN 0036-8075, 09/2019, Volume 365, Issue 6457, pp. 1025 - 1025
Treatment of SIV-infected rhesus macaques with short-term antiretroviral therapy (ART) and partially overlapping infusions of antibody to integrin a 4 0 7 was... 
INTEGRIN ALPHABETA | SIMIAN IMMUNODEFICIENCY VIRUS | MULTIDISCIPLINARY SCIENCES | DISEASE | SUBSETS | RECEPTOR | MACAQUES | TISSUES | DISCOVERY
Journal Article
LABORATORY INVESTIGATION, ISSN 0023-6837, 09/2015, Volume 95, Issue 9, pp. 976 - 986
Integrin alpha 6 beta 4 is a cellular adhesion molecule that binds to laminins in the extracellular matrix and nucleates the formation of hemidesmosomes.... 
BREAST-CANCER | MEDICINE, RESEARCH & EXPERIMENTAL | DIFFERENTIAL EXPRESSION | 6 BETA 4 | PHOSPHOINOSITIDE 3-OH KINASE | ALPHABETA INTEGRIN | PANCREATIC-CANCER | SQUAMOUS-CELL CARCINOMA | ADHESION MOLECULES | PATHOLOGY | INTRAEPITHELIAL NEOPLASIA | UP-REGULATION
Journal Article
Current Opinion in Cell Biology, ISSN 0955-0674, 2011, Volume 23, Issue 5, pp. 607 - 614
Highlights ► Integrin activation mechanisms differ between individual integrins. ► Integrin activation mechanisms differ for non-adherent and adherent cells. ►... 
Internal Medicine | MIGRATION | KINDLIN-3 | RAB21 | ADHESION | ALPHABETA | TALIN | ENDOCYTOSIS | CELL | BINDING | ALPHA-5-BETA-1 INTEGRIN | CELL BIOLOGY | Integrin beta1 - metabolism | Endocytosis | Animals | Signal Transduction | Humans | Integrins - chemistry | Cell Adhesion | Integrins - metabolism | Cell Movement | Protein Transport | Integrins
Journal Article
HUMAN PATHOLOGY, ISSN 0046-8177, 03/2017, Volume 61, pp. 223 - 224
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 08/2013, Volume 369, Issue 8, pp. 699 - 710
Journal Article
NATURE IMMUNOLOGY, ISSN 1529-2908, 12/2013, Volume 14, Issue 12, pp. 1256 - 1256
The humoral immune response after acute infection with HIV-1 is delayed and ineffective. The HIV-1 envelope protein gp120 binds to and signals through integrin... 
INDIVIDUALS | RESPONSES | GROWTH-FACTOR-BETA | INTEGRIN ALPHABETA | DENDRITIC CELLS | TISSUE | HUMORAL IMMUNITY | IGA PRODUCTION | IMMUNOLOGY | VIRUS TYPE-1 INFECTION | T-CELLS
Journal Article
Chemical Communications, ISSN 1359-7345, 2019, Volume 55, Issue 8, pp. 1060 - 1063
We report a novel fluorescent bioprobe, tetraphenylethylene-Phe-Asp-Gly-Glu-Ala (TPE-FDGEA), and its self-assembly behavior, photophysical properties, and... 
HYDROGELS | DESIGN | INTEGRIN ALPHABETA | FLUORESCENCE | PROSTATE-CANCER | LIGHT | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
BRITISH JOURNAL OF PHARMACOLOGY, ISSN 0007-1188, 05/2013, Volume 169, Issue 1, pp. 51 - 68
Background and Purpose AMG 181 is a human anti-47 antibody currently in phase 1 and 2 trials in subjects with inflammatory bowel diseases. AMG 181 specifically... 
inflammatory bowel diseases | INTEGRIN | ULCERATIVE-COLITIS | BETA-7 | Crohn's disease | MONOCLONAL-ANTIBODY | NATALIZUMAB | MUCOSAL | anti-alphabeta | T cells | ACTIVE CROHNS-DISEASE | VEDOLIZUMAB | ADHESION | alphabeta integrin | AFFINITY | AMG 181 | gut-homing | cell trafficking | PHARMACOLOGY & PHARMACY | ulcerative colitis | human antibody
Journal Article
AMERICAN JOURNAL OF PATHOLOGY, ISSN 0002-9440, 11/2010, Volume 177, Issue 5, pp. 2527 - 2540
Alport syndrome is a common hereditary basement membrane disorder caused by mutations in the collagen IV alpha 3, alpha 4, or alpha 5 genes that results in... 
CRESCENTIC GLOMERULONEPHRITIS | MATRIX METALLOPROTEINASES | RECESSIVE ALPORT SYNDROME | ALPHABETA | INFLAMMATION | MESANGIAL CELLS | CELL-ADHESION | BINDING INTEGRINS | PATHOLOGY | T-CELLS | ALPHABETA INTEGRINS
Journal Article
by Li, C and Yang, Z and Du, Y and Tang, HD and Chen, J and Hu, DQ and Fan, ZS
CLINICAL CANCER RESEARCH, ISSN 1078-0432, 08/2014, Volume 20, Issue 15, pp. 4001 - 4013
Purpose: To identify a novel biomarker for bladder cancer targeting therapy. Experimental Design: The human bladder cancer cell line T24 cells were used as... 
MIGRATION | PATHWAYS | BETA-1-INTEGRIN | ALPHABETA INTEGRIN | TUMOR PROGRESSION | ONCOLOGY | FOCAL ADHESION KINASE | CELL-LINES | EXPRESSION | ANTIGEN
Journal Article
Gastroenterology, ISSN 0016-5085, 2014, Volume 147, Issue 3, pp. 618 - 627.e3
Journal Article
NATURE, ISSN 0028-0836, 04/2007, Volume 446, Issue 7136, pp. 680 - 684
Semaphorins are axon guidance factors that assist growing axons in finding appropriate targets and forming synapses(1). Emerging evidence suggests that... 
ADHESION | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | COLITIS | ALPHABETA | MULTIDISCIPLINARY SCIENCES | TRANSMEMBRANE | ARTHRITIS | EXPRESSION | COLLAGEN-BINDING INTEGRINS | FAMILY | HYPERSENSITIVITY
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2017, Volume 114, Issue 18, pp. 4685 - 4690
Journal Article
PLOS ONE, ISSN 1932-6203, 10/2016, Volume 11, Issue 10
Functional cross-talk between Tie2 and Integrin signaling pathways is essential to coordinate endothelial cell adhesion and migration in response to the... 
CELL-CELL | MIGRATION | ACTIVATION | BETA-1-INTEGRIN | ANGIOGENESIS | ALPHABETA | MULTIDISCIPLINARY SCIENCES | CRYSTAL-STRUCTURES | GROWTH-FACTOR | ALPHA(V)BETA INTEGRIN | ALPHA-5-BETA-1 INTEGRIN
Journal Article
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