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Journal of Animal and Veterinary Advances, ISSN 1680-5593, 01/2014, Volume 204, Issue 2, pp. 231 - 245
Nuclear factor kappa B (NF-kappa B) essential modulator (NEMO), a regulatory component of the I kappa B kinase (IKK) complex, controls NF-kappa B activation... 
LYS63-LINKED POLYUBIQUITINATION | RECRUITMENT | ACTIVATION | COMPLEX | RECEPTOR-ASSOCIATED KINASE | CONJUGATING ENZYME | ALPHA | CHAINS | NF-KAPPA-B | DEFICIENCY | CELL BIOLOGY | Receptors, Tumor Necrosis Factor - metabolism | Tumor Necrosis Factor-alpha - metabolism | Interleukin-1 - metabolism | Interleukin-1 Receptor-Associated Kinases - metabolism | Interleukin-1 - analysis | Signal Transduction | Humans | Ubiquitin - metabolism | Receptors, Tumor Necrosis Factor - analysis | NF-kappa B - metabolism | I-kappa B Kinase - analysis | Ubiquitin - genetics | Interleukin-1 Receptor-Associated Kinases - analysis | Ubiquitin - physiology | Receptors, Interleukin-1 - analysis | Receptors, Interleukin-1 - metabolism | Tumor Necrosis Factor-alpha - analysis | Ubiquitination | I-kappa B Kinase - metabolism | Interleukin-1 - physiology | Tumor Necrosis Factor-alpha - physiology | Cell Line, Tumor | HeLa Cells | NF-kappa B - analysis | Ubiquitin | Exhibitions | Interleukins | Tumor necrosis factor | TNF inhibitors | Biochemistry | Cytokines | Molecular biology | Kinases | Index Medicus | Interleukin-1 | Biochemistry, Molecular Biology | Interleukin-1 Receptor-Associated Kinases | I-kappa B Kinase | Tumor Necrosis Factor-alpha | Life Sciences | NF-kappa B | Receptors, Tumor Necrosis Factor | Biomolecules | Receptors, Interleukin-1
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 11/2012, Volume 122, Issue 11, pp. 3965 - 3976
Psoriasis is a chronic inflammatory disorder of the skin affecting approximately 2% of the world's population. Accumulating evidence has revealed that the... 
GENERALIZED PUSTULAR PSORIASIS | MEDICINE, RESEARCH & EXPERIMENTAL | INFLAMMATORY SKIN-DISEASE | FAMILY-MEMBERS | MOUSE MODEL | DELTA-T-CELLS | NF-KAPPA-B | AUTOINFLAMMATORY DISEASE | INTERLEUKIN-12/23 MONOCLONAL-ANTIBODY | CUTTING EDGE | TRANSGENIC MICE | Cell Communication - immunology | Interleukin-1 - genetics | Membrane Glycoproteins - metabolism | Dermatitis - immunology | Dendritic Cells - immunology | Receptors, Interleukin-1 - genetics | Interleukin-17 - immunology | Dendritic Cells - pathology | Interleukins - metabolism | Interleukin-23 - genetics | Interleukins - genetics | Psoriasis - genetics | Interleukin-23 - metabolism | Psoriasis - pathology | Interleukins - immunology | Toll-Like Receptor 7 - immunology | Interleukin-1 - immunology | Psoriasis - metabolism | Membrane Glycoproteins - immunology | Dendritic Cells - metabolism | Psoriasis - immunology | Toll-Like Receptor 7 - genetics | Interleukin-1 - metabolism | Toll-Like Receptor 7 - metabolism | Dermatitis - genetics | Receptors, Interleukin-1 - immunology | Interleukin-17 - genetics | Cell Communication - genetics | Interleukin-23 - immunology | Keratinocytes - immunology | Membrane Glycoproteins - genetics | Mice, Knockout | Receptors, Interleukin-1 - metabolism | Dermatitis - pathology | Interleukin-17 - metabolism | Keratinocytes - pathology | Animals | Keratinocytes - metabolism | Mice | Dermatitis - metabolism | Psoriasis | Interleukins | Keratinocytes | Genetic aspects | Dosage and administration | Diagnosis | Drug therapy | Index Medicus | Abridged Index Medicus | TLR7 protein | Dendritic cells | Mesenchyme | Interleukin 22 | Interleukin 23 | Leukocytes (neutrophilic) | Interleukin 1 receptors | Dermatitis | Inflammatory diseases | Interleukin 17 | Toll-like receptors | Skin
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2009, Volume 106, Issue 17, pp. 7119 - 7124
Journal Article
PLoS Computational Biology, ISSN 1553-734X, 2014, Volume 10, Issue 2, pp. e1003470 - e1003470
Interleukin-1 (IL-1) is a large cytokine family closely related to innate immunity and inflammation. IL-1 proteins are key players in signaling pathways such... 
DATA-BANK | KINASE | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | INTERFACES | PROTEIN-PROTEIN INTERACTIONS | RECEPTOR | SCALE | MOLECULAR DOCKING | EXPRESSION | SOMATIC MUTATIONS | BRAIN-TUMORS | Interleukin-1 Receptor Accessory Protein - genetics | MAP Kinase Kinase 7 - genetics | Neoplasms - metabolism | Interleukin-1 - genetics | Interleukin-1 Receptor Accessory Protein - chemistry | Humans | MAP Kinase Kinase 7 - chemistry | Mitogen-Activated Protein Kinase 9 - genetics | Mitogen-Activated Protein Kinase 10 - genetics | MAP Kinase Kinase 7 - metabolism | Interleukin-1 Receptor Accessory Protein - metabolism | Receptors, Interleukin-1 Type I - metabolism | Inflammation - metabolism | MAP Kinase Kinase 4 - metabolism | Neoplasms - genetics | Computer Simulation | Receptors, Interleukin-1 Type I - chemistry | Interleukin-1 - chemistry | Oncogenes | Mitogen-Activated Protein Kinase 9 - chemistry | Interleukin-1 - metabolism | Protein Interaction Maps - immunology | Signal Transduction | Mitogen-Activated Protein Kinase 9 - metabolism | Computational Biology | Models, Molecular | Inflammation - immunology | Mitogen-Activated Protein Kinase 10 - metabolism | Mitogen-Activated Protein Kinase 10 - chemistry | Mutagenesis | Protein Interaction Maps - genetics | Models, Biological | Neoplasms - immunology | Receptors, Interleukin-1 Type I - genetics | Inflammation - genetics | MAP Kinase Kinase 4 - chemistry | MAP Kinase Kinase 4 - genetics | Polymorphism, Single Nucleotide | Mutation | Complications and side effects | Interleukin-1 | Patient outcomes | Physiological aspects | Development and progression | Inflammation | Genetic aspects | Research | Risk factors | Genetic polymorphisms | Apoptosis | Index Medicus | Proteins | Cytokines | Disease | Kinases | Cancer
Journal Article
Immunity, ISSN 1074-7613, 09/2017, Volume 47, Issue 3, pp. 510 - 523.e4
Journal Article
Journal Article
Nature, ISSN 0028-0836, 03/2006, Volume 440, Issue 7081, pp. 237 - 241
Journal Article
Epilepsia, ISSN 0013-9580, 12/2005, Volume 46, Issue 12, pp. 1906 - 1913
Purpose: Despite the prevalence of febrile convulsions (FCs), their pathophysiology has remained elusive. We tested the hypothesis that components of the... 
Interleukin‐1β | Interleukin‐1–receptor antagonist | Fever | LPS | Seizures | Interleukin-1-receptor antagonist | Interleukin-1β | BACTERIAL LIPOPOLYSACCHARIDE | TEMPORAL-LOBE EPILEPSY | INTERLEUKIN-1 RECEPTOR ANTAGONIST | STATUS EPILEPTICUS | interleukin-1-receptor antagonist | fever | GLIA ACTIVATION | CLINICAL NEUROLOGY | HIPPOCAMPUS | interleukin-1 beta | MESSENGER-RNA | GENE | seizures | EXPRESSION | Brain Chemistry - drug effects | Dose-Response Relationship, Immunologic | Receptors, Interleukin-1 - drug effects | Hippocampus - chemistry | Seizures, Febrile - immunology | Injections, Intraventricular | Hippocampus - drug effects | Cytokines - physiology | Cerebral Cortex - physiopathology | Seizures, Febrile - physiopathology | Sialoglycoproteins - physiology | Sialoglycoproteins - pharmacology | Interleukin-1 - immunology | Interleukin-1 - physiology | Female | Chemokines - pharmacology | Cerebral Cortex - drug effects | Hypothalamus - drug effects | Sialoglycoproteins - immunology | Brain Chemistry - immunology | Chemokines - immunology | Cytokines - immunology | Disease Models, Animal | Animals, Newborn | Cerebral Cortex - chemistry | Hypothalamus - immunology | Hippocampus - immunology | Chemokines - physiology | Rats | Seizures, Febrile - chemically induced | Hypothalamus - physiopathology | Rats, Sprague-Dawley | Interleukin-1 - pharmacology | Brain - drug effects | Animals | Interleukin 1 Receptor Antagonist Protein | Receptors, Interleukin-1 - physiology | Receptors, Interleukin-1 - antagonists & inhibitors | Brain - immunology | Hippocampus - physiopathology | Cytokines - pharmacology | Index Medicus
Journal Article
Nature Immunology, ISSN 1529-2908, 03/2015, Volume 16, Issue 4, pp. 354 - 365
Interleukin 37 (IL-37) and IL-1R8 (SIGIRR or TIR8) are anti-inflammatory orphan members of the IL-1 ligand family and IL-1 receptor family, respectively. Here... 
CELLS | FAMILY-MEMBER | INFLAMMATION | TIR8/SIGIRR | INFECTION | IMMUNOLOGY | TOLL | INHIBITOR | EXPRESSION | NEGATIVE REGULATOR | MOLECULES | Inflammation - pathology | Interleukin-1 - genetics | RNA, Small Interfering - genetics | RNA-Binding Proteins - genetics | Humans | Receptors, Interleukin-1 - genetics | NF-kappa B - immunology | Receptor Protein-Tyrosine Kinases - immunology | Proto-Oncogene Proteins c-fyn - genetics | Signal Transduction - immunology | TOR Serine-Threonine Kinases - genetics | PTEN Phosphohydrolase - immunology | RNA, Small Interfering - immunology | Receptors, Interleukin-1 - deficiency | Leukocytes, Mononuclear - immunology | c-Mer Tyrosine Kinase | Interleukin-1 - immunology | Interleukin-18 Receptor alpha Subunit - genetics | Proto-Oncogene Proteins - immunology | Proto-Oncogene Proteins c-fyn - immunology | STAT3 Transcription Factor - genetics | Cell Line | PTEN Phosphohydrolase - genetics | Interleukin-18 Receptor alpha Subunit - immunology | Leukocytes, Mononuclear - drug effects | MAP Kinase Kinase Kinases - genetics | Receptors, Interleukin-1 - immunology | RNA-Binding Proteins - immunology | Gene Expression Regulation | Mice, Transgenic | Proto-Oncogene Proteins - genetics | Inflammation - immunology | Immunity, Innate | MAP Kinase Kinase Kinases - immunology | Interleukin-18 Receptor alpha Subunit - antagonists & inhibitors | Leukocytes, Mononuclear - pathology | TOR Serine-Threonine Kinases - immunology | Animals | NF-kappa B - genetics | Receptor Protein-Tyrosine Kinases - genetics | Lipopolysaccharides - pharmacology | Inflammation - genetics | Protein Binding | Mice | STAT3 Transcription Factor - immunology | Receptors, Interleukin-1 - antagonists & inhibitors | Index Medicus
Journal Article