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Journal of Animal and Veterinary Advances, ISSN 1680-5593, 01/2014, Volume 204, Issue 2, pp. 231 - 245
Nuclear factor kappa B (NF-kappa B) essential modulator (NEMO), a regulatory component of the I kappa B kinase (IKK) complex, controls NF-kappa B activation... 
LYS63-LINKED POLYUBIQUITINATION | RECRUITMENT | ACTIVATION | COMPLEX | RECEPTOR-ASSOCIATED KINASE | CONJUGATING ENZYME | ALPHA | CHAINS | NF-KAPPA-B | DEFICIENCY | CELL BIOLOGY | Receptors, Tumor Necrosis Factor - metabolism | Tumor Necrosis Factor-alpha - metabolism | Interleukin-1 - metabolism | Interleukin-1 Receptor-Associated Kinases - metabolism | Interleukin-1 - analysis | Signal Transduction | Humans | Ubiquitin - metabolism | Receptors, Tumor Necrosis Factor - analysis | NF-kappa B - metabolism | I-kappa B Kinase - analysis | Ubiquitin - genetics | Interleukin-1 Receptor-Associated Kinases - analysis | Ubiquitin - physiology | Receptors, Interleukin-1 - analysis | Receptors, Interleukin-1 - metabolism | Tumor Necrosis Factor-alpha - analysis | Ubiquitination | I-kappa B Kinase - metabolism | Interleukin-1 - physiology | Tumor Necrosis Factor-alpha - physiology | Cell Line, Tumor | HeLa Cells | NF-kappa B - analysis | Ubiquitin | Exhibitions | Interleukins | Tumor necrosis factor | TNF inhibitors | Biochemistry | Cytokines | Molecular biology | Kinases | Index Medicus | Interleukin-1 | Biochemistry, Molecular Biology | Interleukin-1 Receptor-Associated Kinases | I-kappa B Kinase | Tumor Necrosis Factor-alpha | Life Sciences | NF-kappa B | Receptors, Tumor Necrosis Factor | Biomolecules | Receptors, Interleukin-1
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 2014, Volume 124, Issue 5, pp. 2198 - 2203
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 05/2008, Volume 28, Issue 10, pp. 3538 - 3547
Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
KINASE-ACTIVITY | SIGNALING PATHWAYS | IMMUNE-RESPONSES | TRAF6 | BIOCHEMISTRY & MOLECULAR BIOLOGY | T-CELL-ACTIVATION | DEFECTIVE INTERLEUKIN-1 | INTERLEUKIN-1 RECEPTOR | GAMMA-DEFICIENT MICE | ADAPTER PROTEIN | MYD88 | CELL BIOLOGY
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2013, Volume 288, Issue 42, pp. 30210 - 30222
Background: MyD88 is an adaptor protein that plays a crucial role in the immune response. Results: We identified residues within the TIR domain of MyD88... 
Signal Transduction | Toll IL-1 Receptor (TIR) Domain | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | Cellular Immune Response | Toll-like Receptor (TLR) | MyD88 | SIGNAL-TRANSDUCTION | RECEPTOR TIR DOMAIN | Mutagenesis | STRUCTURAL BASIS | TOLL-LIKE RECEPTORS | INTERACTION SITES | NF-KAPPA-B | ADAPTER PROTEIN | MOLECULAR-BASIS | FAST INTERACTION REFINEMENT | Interleukin-1 Receptor-Associated Kinases - metabolism | Interleukin-1 Receptor-Associated Kinases - genetics | Toll-Like Receptor 2 - genetics | Monocytes - cytology | Dendritic Cells - immunology | Humans | NF-kappa B - immunology | Monocytes - metabolism | NF-kappa B - metabolism | Monocytes - immunology | Mutation, Missense | Interleukin-1 Receptor-Associated Kinases - immunology | Protein Multimerization - physiology | HEK293 Cells | Myeloid Differentiation Factor 88 - immunology | Dendritic Cells - metabolism | Protein Structure, Tertiary | Mutagenesis, Site-Directed | Myeloid Differentiation Factor 88 - genetics | Toll-Like Receptor 4 - genetics | Toll-Like Receptor 4 - immunology | Toll-Like Receptor 2 - metabolism | Toll-Like Receptor 4 - metabolism | NF-kappa B - genetics | Cell Line, Tumor | Toll-Like Receptor 2 - immunology | Signal Transduction - physiology | Dendritic Cells - cytology | Myeloid Differentiation Factor 88 - metabolism | Amino Acid Substitution | Index Medicus
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 134, Issue 1, pp. 170 - 177
Background Genome-wide association studies identified IL33 and IL-1 receptor–like 1 ( IL1RL1 )/ IL18R1 as asthma susceptibility loci. IL33 and IL1RL1... 
Allergy and Immunology | IL1RL1 | IL33 | Avon Longitudinal Study of Parents and Children study | children | wheezing phenotypes | Prevalence and Incidence of Asthma and Mite Allergy study | asthma | IL33-IL1RL1 pathway | IMMUNOLOGY | IL-33 | GENETIC-VARIATION | ALLERGY | DISEASE | 1ST 6 YEARS | BIRTH COHORT | ATOPY | GENOME-WIDE ASSOCIATION | LIFE | Interleukin-1 Receptor Accessory Protein - genetics | Interleukin-1 Receptor-Like 1 Protein | Respiratory Sounds - immunology | Humans | Receptors, Interleukin-1 - genetics | Child, Preschool | Infant | Male | Interleukins - genetics | Interleukins - immunology | Asthma - immunology | Myeloid Differentiation Factor 88 - immunology | Female | Membrane Glycoproteins - immunology | Child | Infant, Newborn | Genetic Predisposition to Disease | Interleukin-1 Receptor Accessory Protein - immunology | Signal Transduction | Interleukin-33 | Receptors, Interleukin-1 - immunology | Myeloid Differentiation Factor 88 - genetics | Respiratory Sounds - physiopathology | Receptors, Cell Surface - immunology | Asthma - genetics | Membrane Glycoproteins - genetics | Epistasis, Genetic | Polymorphism, Single Nucleotide | Asthma - pathology | Cohort Studies | Receptors, Cell Surface - genetics | Genetic research | Control systems | Genetic aspects | Asthma in children | Analysis | Genomics | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Immunology, ISSN 0022-1767, 10/2003, Volume 171, Issue 8, pp. 4304 - 4310
We previously reported a new Toll/IL-1R (TIR)-containing molecule, named TIR domain-containing adaptor inducing IFN-beta (TRIF). Although initial study... 
TBK1 | IKK-EPSILON | RECOGNITION | PATHWAY | MOLECULE | ENDOTOXIN | INNATE | COMPONENTS | INDUCTION | IMMUNOLOGY | TIRAP | Membrane Glycoproteins - metabolism | Humans | NF-kappa B - metabolism | Adaptor Proteins, Vesicular Transport - metabolism | DNA-Binding Proteins - metabolism | Interferon Regulatory Factor-3 | Signal Transduction - immunology | Toll-Like Receptors | Membrane Glycoproteins - physiology | Interferon-beta - genetics | Receptors, Cell Surface - physiology | Binding, Competitive - immunology | Protein-Serine-Threonine Kinases - metabolism | Cell Line | Proteins - physiology | NF-kappa B - antagonists & inhibitors | Peptide Fragments - metabolism | Adaptor Proteins, Vesicular Transport - physiology | Gene Expression Regulation - immunology | Adaptor Proteins, Vesicular Transport - antagonists & inhibitors | Mice, Inbred C57BL | Cells, Cultured | Interferon-beta - biosynthesis | Receptors, Cell Surface - metabolism | I-kappa B Kinase | Protein Binding - immunology | Interferon-beta - antagonists & inhibitors | Receptors, Interleukin-1 - metabolism | Proteins - genetics | Transcription Factors - metabolism | Two-Hybrid System Techniques | TNF Receptor-Associated Factor 6 | Animals | Proteins - metabolism | Amino Acid Motifs - immunology | Receptors, Interleukin-1 - physiology | Mice | Promoter Regions, Genetic - immunology | Protein Structure, Tertiary - physiology | Index Medicus | Abridged Index Medicus
Journal Article
Nature Medicine, ISSN 1078-8956, 04/2008, Volume 14, Issue 4, pp. 399 - 406
Pathogenic microbes have evolved sophisticated molecular strategies to subvert host defenses. Here we show that virulent bacteria interfere directly with Toll-... 
MEDICINE, RESEARCH & EXPERIMENTAL | UROPATHOGENIC ESCHERICHIA-COLI | 1-(1-NAPHTHYLMETHYL)-PIPERAZINE | BIOCHEMISTRY & MOLECULAR BIOLOGY | VIRULENCE FACTOR | VACCINIA VIRUS | CELL BIOLOGY | INVASION | ANTIMICROBIAL DRUG SUSCEPTIBILITY | BRUCELLA-ABORTUS | URINARY-TRACT | INFECTION | EFFLUX PUMP INHIBITOR | Virulence Factors - genetics | Virulence Factors - physiology | Humans | Receptors, Interleukin-1 - genetics | Virulence | Molecular Sequence Data | Toll-Like Receptors - chemistry | Escherichia coli Proteins - physiology | Brucella - genetics | Pyelonephritis - etiology | Receptors, Interleukin-1 - chemistry | Escherichia coli - pathogenicity | Brucella - immunology | Toll-Like Receptors - physiology | Escherichia coli - physiology | Macrophages - immunology | Macrophages - microbiology | Escherichia coli Infections - etiology | Protein Structure, Tertiary | Amino Acid Sequence | Cell Line | Genes, Bacterial | Signal Transduction | Myeloid Differentiation Factor 88 - genetics | Escherichia coli - immunology | Virulence Factors - chemistry | Immunity, Innate | Brucella - physiology | Sequence Homology, Amino Acid | Animals | Escherichia coli - genetics | Toll-Like Receptors - genetics | Urinary Tract Infections - etiology | Escherichia coli Proteins - genetics | Receptors, Interleukin-1 - physiology | Mice | Escherichia coli Proteins - chemistry | Myeloid Differentiation Factor 88 - metabolism | Brucella - pathogenicity | Proteins | Signal transduction | Medical research | E coli | Cellular biology | Index Medicus | Basic Medicine | Medical and Health Sciences | Microbiology in the medical area | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Immunologi inom det medicinska området | Mikrobiologi inom det medicinska området | Immunology in the medical area
Journal Article
Journal of Immunology, ISSN 0022-1767, 12/2002, Volume 169, Issue 12, pp. 6668 - 6672
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 137, Issue 1, pp. 99 - 107.e7
Journal Article
Journal Article
Journal of Orthopaedic Research, ISSN 0736-0266, 07/2011, Volume 29, Issue 7, pp. 984 - 992
Macrophages phagocytose metallic wear particles and produce mediators, which can induce cellular host response and aseptic implant loosening.... 
Toll‐like receptor | macrophages | total joint arthroplasty | lipopolysaccharide | aseptic loosening | Toll-like receptor | NECROSIS-FACTOR-ALPHA | INDUCED TOLERANCE | SIGNAL-TRANSDUCTION | HIP-ARTHROPLASTY | MESSENGER-RNA | ADHERENT ENDOTOXIN | GENE-EXPRESSION | MOUSE MACROPHAGES | ORTHOPEDICS | NF-KAPPA-B | UP-REGULATION | Interleukin-1 Receptor-Associated Kinases - metabolism | Interleukin-1 Receptor-Associated Kinases - genetics | Rats, Wistar | Toll-Like Receptor 5 - genetics | Toll-Like Receptor 9 - genetics | Lipopolysaccharides - immunology | Toll-Like Receptor 9 - immunology | Bone Marrow Cells - immunology | Interleukin-1 Receptor-Associated Kinases - immunology | Myeloid Differentiation Factor 88 - immunology | Bone Marrow Cells - drug effects | Toll-Like Receptors - metabolism | Macrophages - immunology | Toll-Like Receptor 5 - metabolism | Arthroplasty, Replacement - adverse effects | Phagocytosis - drug effects | Lipopolysaccharides - pharmacokinetics | Bone Marrow Cells - cytology | Titanium - immunology | Toll-Like Receptors - immunology | Cells, Cultured | Myeloid Differentiation Factor 88 - genetics | Phagocytosis - immunology | Rats | Toll-Like Receptor 4 - genetics | Toll-Like Receptor 4 - immunology | Macrophages - cytology | Toll-Like Receptor 4 - metabolism | Toll-Like Receptor 5 - immunology | Animals | Toll-Like Receptors - genetics | Macrophages - drug effects | Titanium - pharmacokinetics | Prosthesis Failure - etiology | Toll-Like Receptor 9 - metabolism | Myeloid Differentiation Factor 88 - metabolism | Index Medicus
Journal Article