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by Koh, J and Kim, HY and Lee, Y and Park, IK and Kang, CH and Kim, YT and Kim, JE and Choi, M and Lee, WW and Jeon, YK and Chung, DH
CLINICAL CANCER RESEARCH, ISSN 1078-0432, 07/2019, Volume 25, Issue 13, pp. 4026 - 4037
Purpose: The plasticity of innate lymphoid cells (ILCs) has been reported in vitro and in the microenvironment of the intestine. However, whether ILC... 
IMMUNITY | INTERLEUKIN-22 | ONCOLOGY | NIVOLUMAB | DOCETAXEL | T-CELLS
Journal Article
World journal of gastroenterology, ISSN 1007-9327, 05/2019, Volume 25, Issue 20, pp. 2473 - 2488
It is challenging to distinguish intestinal tuberculosis from Crohn's disease due to dynamic changes in epidemiology and similar clinical characteristics.... 
Interleukin-22 receptor 1 | Interleukin-22 | Intestinal tuberculosis | Single-nucleotide polymorphism | Multinucleated giant cells | Case Control Study | Crohn’s disease
Journal Article
JOURNAL OF EXPERIMENTAL MEDICINE, ISSN 0022-1007, 06/2013, Volume 210, Issue 6, pp. 1117 - 1124
Retinoic acid (RA), a vitamin A metabolite, modulates mucosal T helper cell responses. Here we examined the role of RA in regulating IL-22 production by gamma... 
MEDICINE, RESEARCH & EXPERIMENTAL | IMMUNITY | RESPONSES | DENDRITIC CELLS | PROTECTION | MECHANISM | INTERLEUKIN-22 | GENERATION | IMMUNOLOGY | BOWEL-DISEASE
Journal Article
NATURE, ISSN 0028-0836, 05/2008, Volume 453, Issue 7191, pp. 106 - 106
The aryl hydrocarbon receptor ( AHR) is a ligand- dependent transcription factor best known for mediating the toxicity of dioxin(1). Environmental factors are... 
ENCEPHALOMYELITIS | ACTIVATION | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | REGULATORY T-CELLS | AH RECEPTOR | INTERLEUKIN-22 | DIFFERENTIATION | NF-KAPPA-B | MICE LACKING | TH17 CELLS
Journal Article
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, ISSN 0091-6749, 06/2009, Volume 123, Issue 6, pp. 1244 - 1252
Background: Psoriasis and atopic dermatitis (AD) are common inflammatory skin diseases. An upregulated T(H)17/IL-23 pathway was demonstrated in psoriasis.... 
TH17 CYTOKINES | INTERLEUKIN-22 | IMMUNOLOGY | IL-22 | LESIONS | ALLERGY | Atopic dermatitis | T22 | psoriasis | T(H)17 | IL-17 | LIGAND | EXPRESSION | SKIN INFLAMMATION
Journal Article
Journal of Neuroimmunology, ISSN 0165-5728, 12/2019, Volume 337, p. 577062
Interleukins (ILs)-22, 32α and 34 were monitored in the sera of relapsing-remitting multiple sclerosis (RRMS) patients at different time intervals with or... 
Multiple sclerosis | Interferon | Fingolimod | Interleukin-22 | Interleukin-34 | Interleukin-32α
Journal Article
Nature Immunology, ISSN 1529-2908, 2009, Volume 10, Issue 1, pp. 75 - 82
NKp46(+)CD3(-) natural killer lymphocytes isolated from blood, lymphoid organs, lung, liver and uterus can produce granule-dependent cytotoxicity and... 
IMMUNITY | NATURAL-KILLER-CELLS | LYMPHOID-TISSUES | DENDRITIC CELLS | B-CELL | INFLAMMATION | NK-CELLS | HOST-DEFENSE | SUBSETS | INTERLEUKIN-22 | IMMUNOLOGY
Journal Article
BLOOD, ISSN 0006-4971, 01/2010, Volume 115, Issue 2, pp. 274 - 281
Human CD56(bright) natural killer (NK) cells possess little or no killer immunoglobulin-like receptors (KIRs), high interferon-gamma (IFN-gamma) production,... 
IMMUNITY | RESPONSES | NATURAL-KILLER-CELLS | INTERFERON-GAMMA | IN-VIVO | INNATE | INTERLEUKIN-22 | MICE | HEMATOLOGY | EXPRESSION
Journal Article
世界胃肠病学杂志:英文版, ISSN 1007-9327, 2016, Issue 6, pp. 2081 - 2091
AIM To investigate the therapeutic effects andmechanisms of interleukin (IL)-22 in liver regenerationin mice with concanavalin A (ConA)-induced liver... 
A | Partialhepatectomy | Interleukin-22 | regeneration | Liver | Concanavalin
Journal Article
JOURNAL OF CLINICAL INVESTIGATION, ISSN 0021-9738, 02/2008, Volume 118, Issue 2, pp. 534 - 544
Expression of IL-22 is induced in several human inflammatory conditions, including inflammatory bowel disease (IBD). Expression of the IL-22 receptor is... 
MEDICINE, RESEARCH & EXPERIMENTAL | MUTANT MICE | CROHNS-DISEASE | CELL-MIGRATION | IN-VIVO | STAT3 | GENE-EXPRESSION | INTERLEUKIN-22 | POTENTIAL ROLE | BOWEL-DISEASE | INNATE IMMUNITY
Journal Article
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 05/2017, Volume 198, Issue 9, pp. 3671 - 3678
Psoriasis is a chronic inflammatory disease resulting from dysregulated immune activation associated with a large local secretion of cytokines. Among them,... 
CELLS | CYTOKINES | PLAQUE PSORIASIS | MOUSE MODEL | HOST-DEFENSE | RECEPTOR | KERATINOCYTES | INTERLEUKIN-22 | IMMUNOLOGY | TH17 | EXPRESSION
Journal Article
世界胃肠病学杂志:英文版, ISSN 1007-9327, 2016, Volume 22, Issue 21, pp. 5023 - 5032
AIM: To investigate the potential protective effect of exogenous recombinant interleukin-22(r IL-22) on L-arginine-induced acute severe... 
transducer | pancreatitis;Lung | and | severe | activ | gene;Signal | Interleukin-22;Acute | injury;Anti-apoptosis | Anti-apoptosis gene | Interleukin-22 | Acute severe pancreatitis | Signal transducer and activator of transcription 3 | Lung injury
Journal Article
CELL, ISSN 0092-8674, 02/2019, Volume 176, Issue 5, pp. 998 - 998
Lung cancer is closely associated with chronic inflammation, but the causes of inflammation and the specific immune mediators have not been fully elucidated.... 
RNA-SEQ | BIOCHEMISTRY & MOLECULAR BIOLOGY | PATTERNS | INTERLEUKIN-22 | MODEL | EXPRESSION | PROGRESSION | INDEPENDENT COMPONENT ANALYSIS | REVEALS | CELL BIOLOGY
Journal Article
Cell, ISSN 0092-8674, 08/2018, Volume 174, Issue 5, pp. 1054 - 1066
Innate lymphoid cells (ILCs) are lymphocytes that do not express the type of diversified antigen receptors expressed on T cells and B cells. ILCs are largely... 
plasticity | metabolism | neuro-immunology | immunity | innate lymphoid cells | tissue remodeling | ROR-GAMMA-T | NK CELLS | PROTECTION | TRANSCRIPTION FACTOR GATA3 | BIOCHEMISTRY & MOLECULAR BIOLOGY | TYPE-2 IMMUNITY | INTERLEUKIN-22 | TUFT CELLS | EXPRESSION | PROMOTES | PLASTICITY | CELL BIOLOGY | Physiological aspects | T cells | B cells | Life Sciences | Immunology
Journal Article
Cellular Signalling, ISSN 0898-6568, 11/2019, Volume 63, p. 109388
Journal Article
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 05/2019, Volume 202, Issue 9, pp. 2609 - 2615
Cholecystokinin (CCK) is a peptide hormone that functions in digestive organs and the CNS. We previously showed that CCK downregulates peripheral pruritus by... 
INTERFERON-ALPHA | MOUSE | DELTA T-CELLS | CYTOKINE | INTERLEUKIN-22 | MICE | DIFFERENTIATION | IMMUNOLOGY | SKIN INFLAMMATION
Journal Article
Journal of Immunology, ISSN 0022-1767, 02/2019, Volume 202, Issue 3, pp. 956 - 965
The cytokine IL-22 is rapidly induced at barrier surfaces where it regulates host-protective antimicrobial immunity and tissue repair but can also enhance... 
STEM-CELLS | COLITIS | INFLAMMATORY RESPONSES | SEQUENCE DATA | MOUSE MODEL | HOST-DEFENSE | INTERLEUKIN-22 | COLONIZATION | FUCOSYLATION | IMMUNOLOGY | EXPRESSION
Journal Article
Journal Article