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Biochimie, ISSN 0300-9084, 12/2015, Volume 119, pp. 175 - 182
Interleukin (IL)-6 and IL-11 are the only canonical members of the IL-6 family of cytokines that induce signaling through a homodimer of the common β-receptor... 
Signal transduction | Proliferation | Interleukin-11 | Proteolysis | Plasticity | Interleukin-6 | ACTIVATION | HUMAN IL-6 RECEPTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | GP130 | LEUKEMIA INHIBITORY FACTOR | CYTOKINE | SIGNAL-TRANSDUCTION | ONCOSTATIN-M | GLYCOPROTEIN 130 | CILIARY NEUROTROPHIC FACTOR | BINDING | Protein Subunits | Receptors, Interleukin-6 - chemistry | Cell Proliferation | Cytokine Receptor gp130 - genetics | Humans | Interleukin-11 Receptor alpha Subunit - agonists | Cytokine Receptor gp130 - agonists | Interleukin-6 Receptor alpha Subunit - metabolism | Interleukin-6 Receptor alpha Subunit - agonists | Protein Interaction Domains and Motifs | Interleukin-11 Receptor alpha Subunit - genetics | Binding Sites | Interleukin-6 - metabolism | Peptide Fragments - genetics | Protein Structure, Tertiary | Recombinant Proteins - metabolism | Cell Line | Peptide Fragments - metabolism | Cytokine Receptor gp130 - metabolism | Interleukin-6 - genetics | Signal Transduction | Receptors, Interleukin-6 - genetics | Cytokine Receptor gp130 - chemistry | Models, Molecular | Recombinant Proteins - chemistry | Interleukin-11 - genetics | Interleukin-11 - metabolism | Interleukin-11 Receptor alpha Subunit - metabolism | Interleukin-6 Receptor alpha Subunit - chemistry | Interleukin-6 Receptor alpha Subunit - genetics | Peptide Fragments - chemistry | Animals | Interleukin-11 Receptor alpha Subunit - chemistry | Peptide Fragments - agonists | Ligands | Mice | Receptors, Interleukin-6 - agonists | Receptors, Interleukin-6 - metabolism | Index Medicus
Journal Article
by Sarwar, Nadeem and Butterworth, Adam S and Freitag, Daniel F and Gregson, John and Willeit, Peter and Gorman, Donal N and Gao, Pei and Saleheen, Danish and Rendon, Augusto and Nelson, Christopher P and Braund, Peter S and Hall, Alistair S and Chasman, Daniel I and Tybjærg-Hansen, Anne and Chambers, John C and Benjamin, Emelia J and Franks, Paul W and Clarke, Robert and Wilde, Arthur A. M and Trip, Mieke D and Steri, Maristella and Witteman, Jacqueline C. M and Qi, Lu and van der Schoot, C. Ellen and de Faire, Ulf and Erdmann, Jeanette and Stringham, Heather M and Koenig, Wolfgang and Rader, Daniel J and Melzer, David and Reich, David and Psaty, Bruce M and Kleber, Marcus E and Panagiotakos, Demosthenes B and Willeit, Johann and Wennberg, Patrik and Woodward, Mark and Adamovic, Svetlana and Rimm, Eric B and Meade, Tom W and Gillum, Richard F and Shaffer, Jonathan A and Hofman, Albert and Onat, Altan and Sundström, Johan and Wassertheil-Smoller, Sylvia and Mellström, Dan and Gallacher, John and Cushman, Mary and Tracy, Russell P and Kauhanen, Jussi and Karlsson, Magnus and Salonen, Jukka T and Wilhelmsen, Lars and Amouyel, Philippe and Cantin, Bernard and Best, Lyle G and Ben-Shlomo, Yoav and Manson, JoAnn E and Davey-Smith, George and de Bakker, Paul I. W and O'Donnell, Christopher J and Wilson, James F and Wilson, Anthony G and Assimes, Themistocles L and Jansson, John-Olov and Ohlsson, Claes and Tivesten, Åsa and Ljunggren, Östen and Reilly, Muredach P and Hamsten, Anders and Ingelsson, Erik and Cambien, Francois and Hung, Joseph and Thomas, G. Neil and Boehnke, Michael and Schunkert, Heribert and Asselbergs, Folkert W and Kastelein, John J. P and Gudnason, Vilmundur and Salomaa, Veikko and Harris, Tamara B and Kooner, Jaspal S and Allin, Kristine H and Nordestgaard, Børge G and Hopewell, Jemma C and Goodall, Alison H and Ridker, Paul M and Hólm, Hilma and Watkins, Hugh and Ouwehand, Willem H and Samani, Nilesh J and Kaptoge, Stephen and Di Angelantonio, Emanuele and Harari, Olivier and Danesh, John and Quertermous, Thomas and Go, Alan S and Hlatky, Mark A and Knowles, Joshua W and ... and IL6R Genetics Consortium Emerging and IL6R Genetics Consortium Emerging Risk Factors Collaboration and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Umeå universitet and Medicin
Lancet, The, ISSN 0140-6736, 2012, Volume 379, Issue 9822, pp. 1205 - 1213
Journal Article
Vascular Pharmacology, ISSN 1537-1891, 2012, Volume 57, Issue 1, pp. 56 - 64
Abstract Objectives Sphingosine 1-phosphate (S1P) – a lysosphingolipid present in HDL – exerts atheroprotective effects in vitro , while FTY720, a... 
Cardiovascular | Sphingosine 1-phosphate (S1P) | Inflammation | High density lipoproteins (HDL) | Atherosclerosis | CHOLESTEROL | ENDOTHELIAL CELL-ADHESION | SPHINGOSINE-1-PHOSPHATE ANALOG | HYPERCHOLESTEROLEMIA | HIGH-DENSITY-LIPOPROTEIN | MACROPHAGE ACCUMULATION | INTERFERON-GAMMA | INSULIN-RESISTANCE | PHARMACOLOGY & PHARMACY | ADIPOSE-TISSUE | Spleen - immunology | Spleen - drug effects | Body Weight - immunology | Antigens, CD - metabolism | CD4-Positive T-Lymphocytes - immunology | Lymphocyte Activation - immunology | Oxadiazoles - pharmacology | Serine Endopeptidases - immunology | CD8-Positive T-Lymphocytes - metabolism | Lymph Nodes - drug effects | Receptors, Lysosphingolipid - metabolism | Interleukin-6 - metabolism | Lymphocytes - metabolism | Propylene Glycols - pharmacology | Atherosclerosis - immunology | CD4-Positive T-Lymphocytes - metabolism | Lymph Nodes - metabolism | Receptors, LDL - metabolism | Lymph Nodes - immunology | Receptors, LDL - immunology | Atherosclerosis - metabolism | Sphingosine - pharmacology | Macrophages - metabolism | Sphingosine - analogs & derivatives | Interleukin-6 - immunology | Receptors, Lysosphingolipid - agonists | Mice | CD8-Positive T-Lymphocytes - immunology | Antigens, CD - immunology | Genes, MHC Class II - immunology | Interleukin-2 - immunology | Lymphocytes - immunology | Female | Propylene Glycols - immunology | Antigens, Differentiation, Myelomonocytic - immunology | Macrophages - immunology | Interleukin-2 - metabolism | Atherosclerosis - drug therapy | CD11b Antigen - immunology | Mice, Inbred C57BL | Proprotein Convertases - metabolism | Fingolimod Hydrochloride | Sphingosine - immunology | Proprotein Convertases - immunology | Receptors, Lysosphingolipid - immunology | Animals | Spleen - metabolism | Antigens, Differentiation, Myelomonocytic - metabolism | CD8-Positive T-Lymphocytes - drug effects | Lymphocytes - drug effects | Macrophages - drug effects | Serine Endopeptidases - metabolism | CD11b Antigen - metabolism | CD4-Positive T-Lymphocytes - drug effects | Indans - pharmacology | Hypercholesterolemia | Blood lipids | Mitogens | Low density lipoproteins | Sphingosine | Index Medicus
Journal Article
Immunity, ISSN 1074-7613, 04/2018, Volume 48, Issue 4, pp. 745 - 759.e6
It is unclear how quiescence is enforced in naive T cells, but activation by foreign antigens and self-antigens is allowed, despite the presence of inhibitory... 
signaling | T cell activation | receptor I downregulation | autoimmunity | NF-kB | TCR signaling | T cell quiescence | TGF-β | CARD11 | IL-6 | GROWTH-FACTOR-BETA | TARGETED DISRUPTION | HOMEOSTASIS | AUTOIMMUNITY | IMMUNOSUPPRESSION | TRANSCRIPTION FACTOR FOXP3 | MECHANISMS | MICE | DIFFERENTIATION | IMMUNOLOGY | NF-KAPPA-B | Cell Proliferation | Humans | Transforming Growth Factor beta1 - metabolism | Colitis - pathology | NF-kappa B - metabolism | CARD Signaling Adaptor Proteins - genetics | CD4-Positive T-Lymphocytes - immunology | Receptor, Transforming Growth Factor-beta Type I - metabolism | Signal Transduction - immunology | CARD Signaling Adaptor Proteins - metabolism | Lymphocyte Activation - immunology | Autoimmunity - immunology | HEK293 Cells | Lupus Erythematosus, Systemic - immunology | Receptors, Antigen, T-Cell - immunology | Colitis - immunology | Transforming Growth Factor beta1 - biosynthesis | Disease Models, Animal | Cell Line | Receptor, Transforming Growth Factor-beta Type I - biosynthesis | Mice, Inbred C57BL | Guanylate Cyclase - metabolism | Mice, Knockout | Animals | Down-Regulation - immunology | Interleukin-6 - immunology | Guanylate Cyclase - genetics | Mice | Mice, Inbred BALB C | Cell proliferation | NF-κB protein | Antigens | Transcription factors | Statistical analysis | Research & development--R&D | Transforming growth factor | Interleukin | Caspase | Autoantigens | Activation | Lymphocytes T | T cell receptors | Experiments | Interleukin 6 | Proteins | T-cell receptor | Mitigation | Studies | Signaling | Cell activation | Lymphocytes | Index Medicus
Journal Article
Journal of Immunology, ISSN 0022-1767, 08/2008, Volume 181, Issue 4, pp. 2277 - 2284
Journal Article
Journal Article
Arthritis & Rheumatology, ISSN 2326-5191, 05/2014, Volume 66, Issue 5, pp. 1185 - 1194
Journal Article