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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2016, Volume 113, Issue 37, pp. E5399 - E5407
Leucine-rich repeat-containing G-protein coupled receptor 5-positive (Lgr5⁺) stem cells reside at crypt bottoms of the small and large intestine. Small... 
Intestinal stem cell | Niche | Lgr5 | Deep crypt secretory cells | Reg4 | niche | intestinal stem cell | deep crypt secretory cells | HOMEOSTASIS | ADENOCARCINOMA | MULTIDISCIPLINARY SCIENCES | IDENTIFICATION | GOBLET CELLS | INTESTINAL CRYPTS | PANETH CELLS | DIFFERENTIATION | REG-IV | EXPRESSION | ADENOMAS | Biological Sciences | PNAS Plus
Journal Article
Science, ISSN 0036-8075, 10/2012, Volume 338, Issue 6103, pp. 108 - 113
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2015, Volume 10, Issue 3, p. e0121980
Lynch syndrome is caused by germline mutations of DNA mismatch repair (MMR) genes, most frequently MLH1 and MSH2. Recently, MMR-deficient crypt foci (MMR-DCF)... 
COLON CANCERS | HNPCC | EVOLUTION | HEREDITARY | NONPOLYPOSIS COLORECTAL-CANCER | MICROSATELLITE INSTABILITY | MULTIDISCIPLINARY SCIENCES | RISK | FRAMESHIFT MUTATIONS | TUMORS | GENETIC ALTERATIONS | MutL Protein Homolog 1 | Microsatellite Instability | Age Factors | Colorectal Neoplasms, Hereditary Nonpolyposis - genetics | Colorectal Neoplasms, Hereditary Nonpolyposis - pathology | Humans | Middle Aged | MutS Homolog 2 Protein - genetics | Aberrant Crypt Foci - pathology | DNA-Binding Proteins - genetics | Aberrant Crypt Foci - genetics | Proteins - genetics | Young Adult | Adaptor Proteins, Signal Transducing - genetics | Adult | Aged | Nuclear Proteins - genetics | bcl-2-Associated X Protein - genetics | Intestinal Mucosa - pathology | Immunohistochemistry | Gene mutations | Colorectal cancer | Transformation | Bax protein | Endometrial cancer | Genes | Mucosa | Colorectal carcinoma | Biology | Microsatellite instability | Inactivation | DNA repair | Proteins | Alterations | Intestine | Mismatch repair | Cooperation | Gastroenterology | Tumorigenesis | Lesions | Repair | Deoxyribonucleic acid--DNA | Medical research | Microsatellites | Stability | Deactivation | MLH1 protein | MSH2 protein | Patients | Molecular chains | Pathology | Crypts | Protein expression | Transformations | Mutation | Cancer | Deoxyribonucleic acid | DNA
Journal Article
Physiological Reports, ISSN 2051-817X, 09/2014, Volume 2, Issue 9, pp. e12147 - n/a
Journal Article