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Metallomics, ISSN 1756-5901, 7/2018, Volume 1, Issue 7, pp. 899 - 916
The labile iron pool (LIP) is a pool of chelatable and redox-active iron, not only essential for a wide variety of metabolic process, but also as a catalyst in... 
Oxidative stress | Mitochondria | Nondestructive testing | Medical treatment | Trafficking | Lysosomes | Fluorescence | Iron | Nuclei | Cytosol
Journal Article
Metallomics, ISSN 1756-5901, 07/2018, Volume 10, Issue 7, pp. 899 - 916
Journal Article
Journal Article
Biochemical Journal, ISSN 0264-6021, 04/2006, Volume 395, Issue 1, pp. 49 - 55
A series of fluorescent iron chelators has been synthesized such that a fluorescent function is covalently linked to a 3-hydroxypyridin-4-one. In the present... 
Hepatocyte | Intracellular labile iron | 3-hydroxypyridin-4-one (HPO) fluorescent probe | Fluorescence microscopy | Iron chelator | Quenching | 3-hydroxy-pyridin-4-one (HPO) fluorescent probe | CELLS | DESIGN | hepatocyte | intracellular labile iron | BIOCHEMISTRY & MOLECULAR BIOLOGY | DESFERRIOXAMINE-AVAILABLE IRON | fluorescence microscopy | ISOLATED RAT HEPATOCYTES | iron chelator | SPECTROSCOPY | THALASSEMIA | CLINICAL-USE | POOL | HYDROGEN-PEROXIDE | quenching | FERRITIN | Fluorescent Dyes - chemistry | Rats, Wistar | Iron - chemistry | Cells, Cultured | Fluorescent Dyes - analysis | Rats | Male | Calibration | Hepatocytes - metabolism | Iron - metabolism | Iron Chelating Agents - chemistry | Iron Chelating Agents - analysis | Iron - analysis | Hepatocytes - cytology | Animals | Cell-Free System | Pyridones - metabolism | Pyridones - analysis | Pyridones - chemistry | CP800, 4- and 5-(2-(3-hydroxy-2-methyl-4-oxopyridin-1(4H)-yl)ethylcarbamoyl)-2-(3-hydroxy-6-oxo-6H-xanthen-9-yl)benzoic acid | CP603, N-[2-(3-hydroxy-2-methyl-4-oxopyridin-1(4H)-yl)ethyl]-2-(7-(dimethylamino)-2-oxo-2H-chromen-4-yl)acetamide | CP623, N-[(3-hydroxy-1,6-dimethyl-4-oxo-1,4-dihydropyridin-2-yl)-methyl]-2-(7-(dimethylamino)-2-oxo-2H-chromen-4-yl)acetamide | CP645, 7-diethylamino-N-[(5-hydroxy-1-methyl-4-oxo-1,4-dihydropyridin-2-yl)methyl]-2-oxo-2H-chromene-3-carboxamide | ClogP, logarithm of calculated partition coefficient | HBSS, Hanks balanced salt solution | CP94, 1,2-diethyl-3-hydroxypyridin-4-one | HPO, 3-hydroxypyridin-4-one | CP655, 7-diethylamino-N-[(5-hydroxy-6-methyl-4-oxo-1,4-dihydropyridin-3-yl)methyl]-N-methyl-2-oxo-2H-chromen-3-carboxamide | DFO, desferrioxamine-B | DTPA, diethylenetriaminepenta-acetic acid
Journal Article
CANCER RESEARCH, ISSN 0008-5472, 03/2006, Volume 66, Issue 5, pp. 2600 - 2607
Hypoxia-inducible factor (HIF) is a transcription factor with major roles in many cellular and systemic responses to hypoxia. Activation of HIF pathways under... 
BREAST-CANCER | FACTOR 1-ALPHA | CELLS | ONCOLOGY | TUMOR-ASSOCIATED MACROPHAGES | PHORBOL-MYRISTATE ACETATE | INTRACELLULAR PATHOGENS | ASCORBIC-ACID | EXPRESSION | NRAMP1 | PROLYL HYDROXYLASES
Journal Article
Journal Article
Antioxidants & Redox Signaling, ISSN 1523-0864, 07/2014, Volume 21, Issue 2, pp. 195 - 210
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 05/2002, Volume 81, Issue 3, pp. 615 - 623
Microglial activation is common in several neurodegenerative disorders. In the present study, we used the murine BV‐2 microglial cell line stimulated with... 
neurodegenerative diseases | nitric oxide | labile iron pool | iron regulatory proteins | microglial cells | respiratory chain | Microglial cells | Labile iron pool | Respiratory chain | Iron regulatory proteins | Neurodegenerative diseases | Nitric oxide | FRIEDREICHS ATAXIA | ALZHEIMERS-DISEASE | MACROPHAGES | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEURODEGENERATION | TUMOR-CELLS | GLIAL-CELLS | NEUROSCIENCES | INHIBITION | MITOCHONDRIAL COMPLEX-I | REGULATORY PROTEIN-1 | PARKINSONS-DISEASE | Aconitate Hydratase - metabolism | Oxidoreductases - antagonists & inhibitors | Microglia - metabolism | Electron Transport Complex I | Nitric Oxide - pharmacology | Multienzyme Complexes - metabolism | Electron Transport Complex II | Adenosine Triphosphate - metabolism | Cell Respiration - drug effects | Electron Transport - physiology | Energy Metabolism - physiology | NADH, NADPH Oxidoreductases - metabolism | Intracellular Fluid - metabolism | RNA - metabolism | Microglia - cytology | Cell Line | Iron-Regulatory Proteins | Microglia - drug effects | Oxidoreductases - metabolism | Succinate Dehydrogenase - antagonists & inhibitors | Aconitate Hydratase - antagonists & inhibitors | Enzyme Activation - drug effects | Multienzyme Complexes - antagonists & inhibitors | Iron - metabolism | Cytochrome c Group - metabolism | Animals | Lipopolysaccharides - pharmacology | Succinate Dehydrogenase - metabolism | Iron-Sulfur Proteins - metabolism | Mice | NADH, NADPH Oxidoreductases - antagonists & inhibitors | Nitric Oxide - metabolism | Energy Metabolism - drug effects | Interferon-gamma - pharmacology | RNA-Binding Proteins - metabolism | Protein Binding - physiology | Electron Transport | Multienzyme Complexes | Succinate Dehydrogenase | RNA | Iron | Adenosine Triphosphate | RNA-Binding Proteins | Lipopolysaccharides | Life Sciences | Cell Respiration | NADH, NADPH Oxidoreductases | Aconitate Hydratase | Intracellular Fluid | Interferon-gamma | Biochemistry, Molecular Biology | Cytochrome c Group | Nitric Oxide | Iron-Sulfur Proteins | Microglia | Energy Metabolism | Protein Binding | Enzyme Activation | Oxidoreductases | cytology | pharmacology | physiology | drug effects | antagonists & inhibitors | metabolism
Journal Article