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Bone, ISSN 8756-3282, 03/2019, Volume 120, pp. 327 - 335
SHP2 is a ubiquitously expressed protein tyrosine phosphatase, which is involved in many signaling pathways to regulate the skeletal development. In... 
SHP2 | TGFβ and BMP2 signaling | Mesenchymal progenitors | Intramembranous ossification | Osteoblast differentiation | OSTERIX | BONE MORPHOGENETIC PROTEIN-2 | PTPN11 | CELL FATE | RUNX2 FUNCTION | GROWTH | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | CBFA1 | PROTEIN-TYROSINE-PHOSPHATASE | TGF beta and BMP2 signaling
Journal Article
Journal Article
Journal Article
Annals of biomedical engineering, ISSN 0090-6964, 04/2019, pp. 1 - 14
Despite its regenerative ability, long and segmental bone defect repair remains a significant orthopedic challenge. Conventional tissue engineering efforts... 
Bone grafts | Hydrogels | Bone (intramembranous) | Biodegradability | Ossification | Recruitment | Cartilage | Hyaluronan | Bone growth | Biomedical materials | Mineralization | Extracellular matrix | Biocompatibility | Polymers | Bone matrix | Bone (endochondral) | Biodegradation | Load bearing elements | Evaluation | Tissue engineering | Bone remodelling | Bone healing | Fibrin | Regeneration | Bone (long) | Bone | Osteogenesis
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 07/2018, Volume 115, Issue 27, pp. E6135 - E6144
In adult bone injuries, periosteum-derived mesenchymal stem/stromal cells (MSCs) form bone via endochondral ossification (EO), whereas those from bone marrow... 
Stem cell niche | Calcium phosphate | Wnt signaling | Bone remodeling | Regenerative medicine | EXTRACELLULAR CA2+-SENSING RECEPTOR | stem cell niche | HORMONE-RELATED PEPTIDE | ACTIVATED PROTEIN-KINASE | OSTEOBLAST DIFFERENTIATION | regenerative medicine | MULTIDISCIPLINARY SCIENCES | BONE-MARROW | MESENCHYMAL STEM-CELLS | CALCIUM-SENSING RECEPTOR | calcium phosphate | MINERALIZATION | BIOLOGY | bone remodeling | EXPRESSION | Chondrogenesis - drug effects | Humans | Osteogenesis - drug effects | Transforming Growth Factor beta1 - metabolism | Apatites - pharmacology | Male | Parathyroid Hormone - pharmacology | Periosteum - metabolism | Down-Regulation - drug effects | Receptors, Calcium-Sensing - metabolism | Periosteum - cytology | Biomimetic Materials - pharmacology | Receptor, Parathyroid Hormone, Type 1 - biosynthesis | Mesenchymal Stem Cells - cytology | Adult | Female | Mesenchymal Stem Cells - metabolism | Physiological aspects | Biomimetics | Observations | Stem cells | Surgical implants | Calcium | Mesenchyme | Bone (intramembranous) | Transforming growth factor | Hydroxyapatite | Bone (trabecular) | Ossification | Bone growth | Biomedical materials | Stimulants | Down-regulation | Bone marrow | Chondrogenesis | Growth factors | Parathyroid | Bone (endochondral) | Health | Periosteum | Parathyroid hormone | Stromal cells | Apatite | In vivo methods and tests | Calcium (extracellular) | Calcium-sensing receptors | Osteogenesis | Index Medicus | Biological Sciences | PNAS Plus
Journal Article
Journal of Bone and Mineral Metabolism, ISSN 0914-8779, 3/2018, Volume 36, Issue 2, pp. 133 - 147
Bone fracture healing is achieved through the proliferation and differentiation of stem cells, while bone marrow stem cells (BMSCs) contribute to endochondral... 
Medicine & Public Health | Endochondral ossification | Orthopedics | Bone fracture | Metabolic Diseases | Geranylgeranyl diphosphate synthase 1 | Intramembranous ossification | MEDICINE, RESEARCH & EXPERIMENTAL | RESORPTION | STATINS | CARTILAGE | FACTOR SOX9 | GENE | BONE-FORMATION | MOUSE MODEL | ENDOCRINOLOGY & METABOLISM | CELL-DIFFERENTIATION | EXPRESSION | CHONDROGENESIS | Femur - pathology | Femur - blood supply | Multienzyme Complexes - metabolism | Ki-67 Antigen - metabolism | Male | Bony Callus - pathology | Femur - diagnostic imaging | Core Binding Factor Alpha 1 Subunit - metabolism | Gene Knockdown Techniques | Farnesyltranstransferase - metabolism | Multienzyme Complexes - deficiency | Bone Morphogenetic Protein 2 - metabolism | Farnesyltranstransferase - deficiency | Chondrocytes - metabolism | Osteogenesis - genetics | Biomarkers - metabolism | Signal Transduction | Gene Expression Regulation | Femur - physiopathology | Mice, Knockout | Biomechanical Phenomena | Animals | Fracture Healing - genetics | Bony Callus - metabolism | Smad Proteins - metabolism | Transforming Growth Factor beta - metabolism | Neovascularization, Physiologic | Medical colleges | Fractures | Collagen | Analysis | Stem cells | Bone morphogenetic proteins | Statins | Cell proliferation | Smad protein | Callus | Mesenchyme | Stem cell transplantation | Osteoblasts | Ossification | Bone growth | Clonal deletion | Rodents | Bone marrow | Bone (endochondral) | Cbfa-1 protein | Bone morphogenetic protein 2 | Bone healing | Tamoxifen | Progenitor cells | Chondrocytes | Calcification | Osteogenesis | Reductase | Index Medicus
Journal Article
Folia Morphologica (Poland), ISSN 0015-5659, 2014, Volume 73, Issue 2, pp. 199 - 205
In the head and neck of human mid-term foetuses, the interface between areas of endochondral ossification and adjacent membranous (intramembranous)... 
Endochondral ossification | Occiput | Tenascin-c | Aggrecan | Human foetus | Pterygoid process | Intramembranous ossification | Versican | STEM-CELLS | pterygoid process | ANATOMY & MORPHOLOGY | tenascin-c | intramembranous ossification | PERICHONDRIUM | human foetus | CARTILAGE | aggrecan | occiput | VESSELS | GROWTH | versican | endochondral ossification | FETAL | TISSUES | Index Medicus
Journal Article
Acta Oto-Laryngologica, ISSN 0001-6489, 04/2012, Volume 132, Issue 4, pp. 349 - 354
Abstract Conclusions: 1. The principle of bilateral symmetry depends on the chordal cartilage that is the keystone in cranial base ossification in rats and... 
neural crest induction | intramembranous | cartilaginous | Bone morphogenetic protein | chordal cartilage | OTORHINOLARYNGOLOGY | Pregnancy | Animals | Orbit - embryology | Carotid Arteries - embryology | Humans | Fetus - embryology | Rats | Female | Skull Base - embryology | Infant, Newborn | Osteogenesis | Branchial Region - embryology | Index Medicus
Journal Article
JOURNAL OF ANATOMY, ISSN 0021-8782, 12/2003, Volume 203, Issue 6, pp. 589 - 598
This paper concerns the role of apoptosis during the onset of bone histogenesis. Previous investigations by us performed on intramembranous ossification... 
static osteogenesis | ANATOMY & MORPHOLOGY | apoptosis | intramembranous ossification | MECHANISMS | PROGRAMMED CELL-DEATH | GROWTH-FACTORS | DISEASE | FAS | osteoblasts | BONE | DIFFERENTIATION | dynamic osteogenesis
Journal Article
Frontiers in Bioengineering and Biotechnology, ISSN 2296-4185, 11/2017, Volume 5, pp. 73 - 73
Journal Article
Journal of Visualized Experiments, ISSN 1940-087X, 04/2012, Issue 62
Assessing modes of skeletal repair is essential for developing therapies to be used clinically to treat fractures. Mechanical stability plays a large role in... 
Medicine | Bone healing | Distraction osteogenesis | Intramembranous ossification | Issue 62 | Bone fracture | MULTIDISCIPLINARY SCIENCES | bone healing | intramembranous ossification | distraction osteogenesis | Animals | Fracture Healing - physiology | Fractures, Bone - pathology | Mice | Ossification, Heterotopic | Osteogenesis | Disease Models, Animal | Index Medicus
Journal Article