JAMA, ISSN 0098-7484, 12/2012, Volume 308, Issue 22, pp. 2369 - 2379
CONTEXT Mesenchymal stem cells (MSCs) are under evaluation as a therapy for ischemic cardiomyopathy (ICM). Both autologous and allogeneic MSC therapies are...
HEART-FAILURE QUESTIONNAIRE | PROGENITOR CELLS | MEDICINE, GENERAL & INTERNAL | THERAPY | PHASE-1 TRIAL | ACUTE MYOCARDIAL-INFARCTION | DOUBLE-BLIND | TRANSCORONARY TRANSPLANTATION | INTRAMYOCARDIAL INJECTION | COMPUTED-TOMOGRAPHY | LEFT-VENTRICULAR SHAPE | Humans | Middle Aged | HLA Antigens - immunology | Male | Transplantation, Autologous | Treatment Outcome | Bone Marrow Transplantation - methods | Transplantation, Homologous | Cardiomyopathies - therapy | Mesenchymal Stromal Cells - immunology | Mesenchymal Stem Cell Transplantation - methods | Ventricular Dysfunction, Left - therapy | Ventricular Remodeling | Myocardial Ischemia - therapy | Quality of Life | Female | Aged | Bone marrow | Medical research | Cardiovascular disease | Injections | Stem cells
HEART-FAILURE QUESTIONNAIRE | PROGENITOR CELLS | MEDICINE, GENERAL & INTERNAL | THERAPY | PHASE-1 TRIAL | ACUTE MYOCARDIAL-INFARCTION | DOUBLE-BLIND | TRANSCORONARY TRANSPLANTATION | INTRAMYOCARDIAL INJECTION | COMPUTED-TOMOGRAPHY | LEFT-VENTRICULAR SHAPE | Humans | Middle Aged | HLA Antigens - immunology | Male | Transplantation, Autologous | Treatment Outcome | Bone Marrow Transplantation - methods | Transplantation, Homologous | Cardiomyopathies - therapy | Mesenchymal Stromal Cells - immunology | Mesenchymal Stem Cell Transplantation - methods | Ventricular Dysfunction, Left - therapy | Ventricular Remodeling | Myocardial Ischemia - therapy | Quality of Life | Female | Aged | Bone marrow | Medical research | Cardiovascular disease | Injections | Stem cells
Journal Article
Circulation Research, ISSN 0009-7330, 04/2014, Volume 114, Issue 8, pp. 1292 - 1301
RATIONALE:Transendocardial stem cell injection (TESI) with mesenchymal stem cells improves remodeling in chronic ischemic cardiomyopathy, but the effect of the...
magnetic resonance imaging | cells | tomography | myocardial infarction | CHRONIC ISCHEMIC CARDIOMYOPATHY | CARDIAC & CARDIOVASCULAR SYSTEMS | REGENERATION | HEART-FAILURE | VIABILITY | INTRAMYOCARDIAL INJECTION | INFARCTION | THERAPY | MAGNETIC-RESONANCE | PERIPHERAL VASCULAR DISEASE | RESTORE CARDIAC-FUNCTION | MULTIDETECTOR COMPUTED-TOMOGRAPHY | HEMATOLOGY | Cicatrix - diagnostic imaging | Cell- and Tissue-Based Therapy - methods | Humans | Middle Aged | Muscle Development - physiology | Stroke Volume - physiology | Male | Treatment Outcome | Myocardial Infarction - diagnostic imaging | Tomography, Spiral Computed | Ventricular Dysfunction, Left - physiopathology | Mesenchymal Stem Cell Transplantation - methods | Myocardial Infarction - therapy | Ventricular Dysfunction, Left - therapy | Injections | Myocardial Infarction - pathology | Female | Aged | Cicatrix - pathology | Cicatrix - therapy
magnetic resonance imaging | cells | tomography | myocardial infarction | CHRONIC ISCHEMIC CARDIOMYOPATHY | CARDIAC & CARDIOVASCULAR SYSTEMS | REGENERATION | HEART-FAILURE | VIABILITY | INTRAMYOCARDIAL INJECTION | INFARCTION | THERAPY | MAGNETIC-RESONANCE | PERIPHERAL VASCULAR DISEASE | RESTORE CARDIAC-FUNCTION | MULTIDETECTOR COMPUTED-TOMOGRAPHY | HEMATOLOGY | Cicatrix - diagnostic imaging | Cell- and Tissue-Based Therapy - methods | Humans | Middle Aged | Muscle Development - physiology | Stroke Volume - physiology | Male | Treatment Outcome | Myocardial Infarction - diagnostic imaging | Tomography, Spiral Computed | Ventricular Dysfunction, Left - physiopathology | Mesenchymal Stem Cell Transplantation - methods | Myocardial Infarction - therapy | Ventricular Dysfunction, Left - therapy | Injections | Myocardial Infarction - pathology | Female | Aged | Cicatrix - pathology | Cicatrix - therapy
Journal Article
Magnetic Resonance in Medicine, ISSN 0740-3194, 06/2004, Volume 51, Issue 6, pp. 1163 - 1172
There is growing interest in delivering cellular agents to infarcted myocardium to prevent postinfarction left ventricular remodeling. MRI can be effectively...
intramyocardial injections | intramyocardial injection catheter | cardiac MRI | interventional MRI | catheter tracking | labeled stem cells | iron oxide MR contrast agent | Interventional MRI | Labeled stem cells | Cardiac MRI | Intramyocardial injection catheter | Catheter tracking | Intramyocardial injections | Iron oxide MR contrast agent | Catheterization | Myocardium - pathology | Oxides | Iron | Equipment Design | Cardiac Catheterization - instrumentation | Magnetic Resonance Imaging | Myocardial Infarction - therapy | Ferrosoferric Oxide | Animals | Contrast Media | Dextrans | Injections, Intralesional | Swine | Myocardial Infarction - pathology | Dogs | Phantoms, Imaging | Magnetite Nanoparticles | Mesenchymal Stem Cell Transplantation
intramyocardial injections | intramyocardial injection catheter | cardiac MRI | interventional MRI | catheter tracking | labeled stem cells | iron oxide MR contrast agent | Interventional MRI | Labeled stem cells | Cardiac MRI | Intramyocardial injection catheter | Catheter tracking | Intramyocardial injections | Iron oxide MR contrast agent | Catheterization | Myocardium - pathology | Oxides | Iron | Equipment Design | Cardiac Catheterization - instrumentation | Magnetic Resonance Imaging | Myocardial Infarction - therapy | Ferrosoferric Oxide | Animals | Contrast Media | Dextrans | Injections, Intralesional | Swine | Myocardial Infarction - pathology | Dogs | Phantoms, Imaging | Magnetite Nanoparticles | Mesenchymal Stem Cell Transplantation
Journal Article
Cell Transplantation, ISSN 0963-6897, 8/2017, Volume 26, Issue 8, pp. 1319 - 1330
Remote and robotically actuated catheters are the stepping-stones toward autonomous catheters, where complex intravascular procedures may be performed with...
robotic catheters | intramyocardial injection | catheterization | feedforward systems | numerical models | MEDICINE, RESEARCH & EXPERIMENTAL | FEASIBILITY | SAFETY | ABLATION | CELL & TISSUE ENGINEERING | TRANSPLANTATION | Catheters - utilization | Humans | Robotic Surgical Procedures - utilization | Original
robotic catheters | intramyocardial injection | catheterization | feedforward systems | numerical models | MEDICINE, RESEARCH & EXPERIMENTAL | FEASIBILITY | SAFETY | ABLATION | CELL & TISSUE ENGINEERING | TRANSPLANTATION | Catheters - utilization | Humans | Robotic Surgical Procedures - utilization | Original
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2017, Volume 1553, pp. 217 - 225
Cardiac regenerative therapy has received attention as a potentially revolutionary approach for treating the damaged heart. The mouse model of myocardial...
Myocardial infarction | Echocardiography | Intramyocardial injection | Stem/progenitor cells | Cardiac tissue engineering | Injections, Intramuscular - instrumentation | Cell- and Tissue-Based Therapy | Therapy, Computer-Assisted - methods | Myocardial Infarction - therapy | Regeneration | Stem Cell Transplantation - methods | Therapy, Computer-Assisted - instrumentation | Animals | Surgery, Computer-Assisted | Myocardium | Mice | Injections, Intramuscular - methods | Disease Models, Animal
Myocardial infarction | Echocardiography | Intramyocardial injection | Stem/progenitor cells | Cardiac tissue engineering | Injections, Intramuscular - instrumentation | Cell- and Tissue-Based Therapy | Therapy, Computer-Assisted - methods | Myocardial Infarction - therapy | Regeneration | Stem Cell Transplantation - methods | Therapy, Computer-Assisted - instrumentation | Animals | Surgery, Computer-Assisted | Myocardium | Mice | Injections, Intramuscular - methods | Disease Models, Animal
Journal Article
MAGNETIC RESONANCE IN MEDICINE, ISSN 0740-3194, 06/2004, Volume 51, Issue 6, pp. 1163 - 1172
There is growing interest in delivering cellular agents to infarcted myocardium to prevent postinfarction left ventricular remodeling. MRI can be effectively...
INTERVENTIONAL DEVICES | SWINE | catheter tracking | GUIDANCE | MODEL | labeled stem cells | iron oxide MR contrast agent | MESENCHYMAL STEM-CELLS | HEART | COIL | intramyocardial injections | intramyocardial injection catheter | cardiac MRI | interventional MRI | IN-VIVO | MAGNETIC-RESONANCE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
INTERVENTIONAL DEVICES | SWINE | catheter tracking | GUIDANCE | MODEL | labeled stem cells | iron oxide MR contrast agent | MESENCHYMAL STEM-CELLS | HEART | COIL | intramyocardial injections | intramyocardial injection catheter | cardiac MRI | interventional MRI | IN-VIVO | MAGNETIC-RESONANCE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Journal Article
Scientific Reports, ISSN 2045-2322, 05/2016, Volume 6, Issue 1, p. 25932
Cardiovascular protein therapeutics such as neuregulin (NRG1) and acidic-fibroblast growth factor (FGF1) requires new formulation strategies that allow for...
SWINE MODEL | DRUG | FIBROBLAST GROWTH FACTOR-2 | STEM-CELLS | MYOCARDIAL-INFARCTION | PLGA MICROPARTICLES | MULTIDISCIPLINARY SCIENCES | HEART-FAILURE | DOUBLE-BLIND | FACTOR-I | DELIVERY | Cell Line | Lactic Acid | Polyglycolic Acid | Male | Treatment Outcome | Administration, Cutaneous | Myocardial Reperfusion Injury - physiopathology | Injections | Animals | Swine | Swine, Miniature | Female | Heart Function Tests - drug effects | Mice | Myocardial Reperfusion Injury - drug therapy | Neuregulin-1 - administration & dosage | Fibroblast Growth Factor 1 - administration & dosage | Disease Models, Animal | Heart | Fibroblast growth factor | Fibroblast growth factor 1 | Echocardiography | Neuregulin 1 | Mapping | Evaporation | Bioavailability | Injection | Microparticles | Catheters | Vascularization | Reperfusion | Ischemia | Glycolic acid | Myocardium | Neuregulin | Growth factors | Heart diseases
SWINE MODEL | DRUG | FIBROBLAST GROWTH FACTOR-2 | STEM-CELLS | MYOCARDIAL-INFARCTION | PLGA MICROPARTICLES | MULTIDISCIPLINARY SCIENCES | HEART-FAILURE | DOUBLE-BLIND | FACTOR-I | DELIVERY | Cell Line | Lactic Acid | Polyglycolic Acid | Male | Treatment Outcome | Administration, Cutaneous | Myocardial Reperfusion Injury - physiopathology | Injections | Animals | Swine | Swine, Miniature | Female | Heart Function Tests - drug effects | Mice | Myocardial Reperfusion Injury - drug therapy | Neuregulin-1 - administration & dosage | Fibroblast Growth Factor 1 - administration & dosage | Disease Models, Animal | Heart | Fibroblast growth factor | Fibroblast growth factor 1 | Echocardiography | Neuregulin 1 | Mapping | Evaporation | Bioavailability | Injection | Microparticles | Catheters | Vascularization | Reperfusion | Ischemia | Glycolic acid | Myocardium | Neuregulin | Growth factors | Heart diseases
Journal Article
Journal of Cardiovascular Translational Research, ISSN 1937-5387, 10/2013, Volume 6, Issue 5, pp. 816 - 825
In experimental studies, mesenchymal stem cell (MSC) transplantation in acute myocardial infarction (AMI) models has been associated with enhanced...
Human Genetics | Biomedical Engineering | Medicine & Public Health | Acute myocardial infarction patients | Intramyocardial injection | Cardiology | Clinical stem cell therapy | Medicine/Public Health, general | Biomedicine general | Mesenchymal stem cells | MEDICINE, RESEARCH & EXPERIMENTAL | CONTROLLED-TRIAL | CARDIAC & CARDIOVASCULAR SYSTEMS | HEART-FAILURE | CHRONIC ISCHEMIA | TRANSPLANTATION | DELIVERY | THERAPY | INTRACORONARY | EJECTION FRACTION | STROMAL CELLS | LEFT-VENTRICULAR FUNCTION | Myocardial Infarction - diagnosis | Myocardial Infarction - surgery | Mesenchymal Stem Cell Transplantation - mortality | Myocardial Infarction - mortality | Cell Proliferation | Ventricular Function, Left | Cell Separation | Humans | Middle Aged | Cells, Cultured | Kaplan-Meier Estimate | Male | Transplantation, Autologous | Treatment Outcome | Mesenchymal Stem Cell Transplantation - adverse effects | Recovery of Function | Feasibility Studies | Disease-Free Survival | Injections | Time Factors | Female | Myocardial Infarction - physiopathology | Aged | Percutaneous Coronary Intervention | Transplantation | Neovascularization | Cardiac patients | Heart attack | Stem cells
Human Genetics | Biomedical Engineering | Medicine & Public Health | Acute myocardial infarction patients | Intramyocardial injection | Cardiology | Clinical stem cell therapy | Medicine/Public Health, general | Biomedicine general | Mesenchymal stem cells | MEDICINE, RESEARCH & EXPERIMENTAL | CONTROLLED-TRIAL | CARDIAC & CARDIOVASCULAR SYSTEMS | HEART-FAILURE | CHRONIC ISCHEMIA | TRANSPLANTATION | DELIVERY | THERAPY | INTRACORONARY | EJECTION FRACTION | STROMAL CELLS | LEFT-VENTRICULAR FUNCTION | Myocardial Infarction - diagnosis | Myocardial Infarction - surgery | Mesenchymal Stem Cell Transplantation - mortality | Myocardial Infarction - mortality | Cell Proliferation | Ventricular Function, Left | Cell Separation | Humans | Middle Aged | Cells, Cultured | Kaplan-Meier Estimate | Male | Transplantation, Autologous | Treatment Outcome | Mesenchymal Stem Cell Transplantation - adverse effects | Recovery of Function | Feasibility Studies | Disease-Free Survival | Injections | Time Factors | Female | Myocardial Infarction - physiopathology | Aged | Percutaneous Coronary Intervention | Transplantation | Neovascularization | Cardiac patients | Heart attack | Stem cells
Journal Article
International Journal for Numerical Methods in Biomedical Engineering, ISSN 2040-7939, 09/2019, Volume 35, Issue 9, pp. e3213 - n/a
Myocardial infarction, or heart attack, is the leading cause of mortality globally. Although the treatment of myocardial infarct has improved significantly,...
Finite element method | Cardiac modeling | Intramyocardial injection | Diffusion tensor magnetic resonance imaging | Diffusion tensor imaging | CARDIAC-FUNCTION | MYOCARDIUM | VENTRICULAR-FUNCTION | ENGINEERING, BIOMEDICAL | HYDROGEL | DELIVERY | DIFFUSION TENSOR | ACTIVE-STRAIN | MECHANICS | MATHEMATICS, INTERDISCIPLINARY APPLICATIONS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | DYNAMICS | STRESS | Myocardial infarction | Heart | Animal models | Medical services | Remodeling | Biomaterials | Biomedical materials | Animal tissues | Attenuation | Degeneration | Mathematical models | Heart diseases | Material properties | Thickening | Heart failure | Computer simulation | Therapeutic applications | Cardiomyocytes | Injection | Tensors | Magnetic resonance imaging | Computer applications | Strategy | Ventricle | Ejection
Finite element method | Cardiac modeling | Intramyocardial injection | Diffusion tensor magnetic resonance imaging | Diffusion tensor imaging | CARDIAC-FUNCTION | MYOCARDIUM | VENTRICULAR-FUNCTION | ENGINEERING, BIOMEDICAL | HYDROGEL | DELIVERY | DIFFUSION TENSOR | ACTIVE-STRAIN | MECHANICS | MATHEMATICS, INTERDISCIPLINARY APPLICATIONS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | DYNAMICS | STRESS | Myocardial infarction | Heart | Animal models | Medical services | Remodeling | Biomaterials | Biomedical materials | Animal tissues | Attenuation | Degeneration | Mathematical models | Heart diseases | Material properties | Thickening | Heart failure | Computer simulation | Therapeutic applications | Cardiomyocytes | Injection | Tensors | Magnetic resonance imaging | Computer applications | Strategy | Ventricle | Ejection
Journal Article
Catheterization and Cardiovascular Interventions, ISSN 1522-1946, 03/2002, Volume 55, Issue 3, pp. 392 - 397
Direct intramyocardial injection may permit local delivery of protein and gene therapy agents for myocardial and coronary artery disease. Little is known about...
intramyocardial drug administration | catheter | gene transfer | endomyocardial | Catheter | Intramyocardial drug administration | Endomyocardial | Gene transfer | REVASCULARIZATION | CARDIAC & CARDIOVASCULAR SYSTEMS | ANGIOGENESIS | NEUTRON-ACTIVATION ANALYSIS | FIBROBLAST-GROWTH-FACTOR | BLOOD-FLOW | DELIVERY | HEART | INTRACORONARY | GENE-TRANSFER | EFFICIENT | Gene Transfer Techniques | Genetic Therapy | Adenoviridae | Fluoroscopy | Cardiac Catheterization - instrumentation | Drug Delivery Systems | Microspheres | Animals | Transfection - methods | Swine | Myocardium - metabolism | Cardiac Catheterization - methods | beta-Galactosidase - metabolism | Needles | Injections - methods
intramyocardial drug administration | catheter | gene transfer | endomyocardial | Catheter | Intramyocardial drug administration | Endomyocardial | Gene transfer | REVASCULARIZATION | CARDIAC & CARDIOVASCULAR SYSTEMS | ANGIOGENESIS | NEUTRON-ACTIVATION ANALYSIS | FIBROBLAST-GROWTH-FACTOR | BLOOD-FLOW | DELIVERY | HEART | INTRACORONARY | GENE-TRANSFER | EFFICIENT | Gene Transfer Techniques | Genetic Therapy | Adenoviridae | Fluoroscopy | Cardiac Catheterization - instrumentation | Drug Delivery Systems | Microspheres | Animals | Transfection - methods | Swine | Myocardium - metabolism | Cardiac Catheterization - methods | beta-Galactosidase - metabolism | Needles | Injections - methods
Journal Article
Journal of Visualized Experiments, ISSN 1940-087X, 01/2018, Volume 2018, Issue 131
Cell and gene therapy are exciting and promising strategies for the purpose of cardiac regeneration in the setting of heart failure with reduced ejection...
Heart failure | Medicine | Animal model | Cell therapy | Issue 131 | Cardiomyopathy | Intramyocardial injection | Contrast echocardiography | intramyocardial injection | heart failure | CHRONIC HEART-FAILURE | INDEPENDENT PREDICTOR | RATE-VARIABILITY | MYOCARDIAL-INFARCTION | VENTRICULAR-FUNCTION | MULTIDISCIPLINARY SCIENCES | DEFICIENT ADENOVIRUS VECTOR | LARGE ANIMAL-MODELS | DILATED CARDIOMYOPATHY | CARDIAC REGENERATION | contrast echocardiography | VIVO GENE-TRANSFER | cell therapy | cardiomyopathy | Rabbits | Animals | Humans | Myocardium - metabolism | Echocardiography - methods | Models, Animal | Heart Failure - diagnostic imaging | Heart Failure - pathology | Injections - methods | Myocardium - cytology
Heart failure | Medicine | Animal model | Cell therapy | Issue 131 | Cardiomyopathy | Intramyocardial injection | Contrast echocardiography | intramyocardial injection | heart failure | CHRONIC HEART-FAILURE | INDEPENDENT PREDICTOR | RATE-VARIABILITY | MYOCARDIAL-INFARCTION | VENTRICULAR-FUNCTION | MULTIDISCIPLINARY SCIENCES | DEFICIENT ADENOVIRUS VECTOR | LARGE ANIMAL-MODELS | DILATED CARDIOMYOPATHY | CARDIAC REGENERATION | contrast echocardiography | VIVO GENE-TRANSFER | cell therapy | cardiomyopathy | Rabbits | Animals | Humans | Myocardium - metabolism | Echocardiography - methods | Models, Animal | Heart Failure - diagnostic imaging | Heart Failure - pathology | Injections - methods | Myocardium - cytology
Journal Article
Computerized Medical Imaging and Graphics, ISSN 0895-6111, 2013, Volume 37, Issue 2, pp. 162 - 173
Abstract Myocardial infarction (MI) is one of the leading causes of death in the world. Small animal studies have shown that stem-cell therapy offers dramatic...
Internal Medicine | Other | MRI | Electromagnetic tracking | X-ray | Cardiac interventions | Image fusion | Stem-cell therapy | 3D ultrasound | PROGENITOR CELLS | STEM-CELLS | COLLATERAL PERFUSION | ENGINEERING, BIOMEDICAL | MONONUCLEAR-CELLS | INTRAMYOCARDIAL INJECTION | AUTOLOGOUS BONE-MARROW | ACUTE MYOCARDIAL-INFARCTION | REGIONAL FUNCTION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | CORONARY-ARTERY-DISEASE | REAL-TIME | Reproducibility of Results | Injections, Intralesional - methods | Humans | Magnetic Resonance Imaging, Interventional - methods | Tomography, X-Ray Computed - methods | Subtraction Technique | Feasibility Studies | Electromagnetic Phenomena | Animals | Swine | Magnetics - methods | Sensitivity and Specificity | Cardiac Catheterization - methods | Multimodal Imaging - methods | Echocardiography, Three-Dimensional - methods | Electromagnetism | Magnetic resonance imaging | Nuclear radiation | Health aspects | Biomedical engineering | Image Fusion | Stem-cell Therapy | Electromagnetic Tracking | 3D Ultrasound | Cardiac Interventions
Internal Medicine | Other | MRI | Electromagnetic tracking | X-ray | Cardiac interventions | Image fusion | Stem-cell therapy | 3D ultrasound | PROGENITOR CELLS | STEM-CELLS | COLLATERAL PERFUSION | ENGINEERING, BIOMEDICAL | MONONUCLEAR-CELLS | INTRAMYOCARDIAL INJECTION | AUTOLOGOUS BONE-MARROW | ACUTE MYOCARDIAL-INFARCTION | REGIONAL FUNCTION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | CORONARY-ARTERY-DISEASE | REAL-TIME | Reproducibility of Results | Injections, Intralesional - methods | Humans | Magnetic Resonance Imaging, Interventional - methods | Tomography, X-Ray Computed - methods | Subtraction Technique | Feasibility Studies | Electromagnetic Phenomena | Animals | Swine | Magnetics - methods | Sensitivity and Specificity | Cardiac Catheterization - methods | Multimodal Imaging - methods | Echocardiography, Three-Dimensional - methods | Electromagnetism | Magnetic resonance imaging | Nuclear radiation | Health aspects | Biomedical engineering | Image Fusion | Stem-cell Therapy | Electromagnetic Tracking | 3D Ultrasound | Cardiac Interventions
Journal Article
JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH, ISSN 1937-5387, 12/2014, Volume 7, Issue 9, pp. 769 - 780
While accumulating clinical trials have focused on the impact of cell therapy in patients with acute myocardial infarction (MI) and ischemic cardiomyopathy,...
Heart failure | MEDICINE, RESEARCH & EXPERIMENTAL | CARDIAC & CARDIOVASCULAR SYSTEMS | FEASIBILITY | FOLLOW-UP | RANDOMIZED-TRIAL | INTRAMYOCARDIAL INJECTION | AUTOLOGOUS SKELETAL MYOBLASTS | TRANSPLANTATION | THERAPY | Dilated cardiomyopathy | ISCHEMIC-HEART FAILURE | Stem cells | ACUTE MYOCARDIAL-INFARCTION | DOUBLE-BLIND | Bone marrow cells
Heart failure | MEDICINE, RESEARCH & EXPERIMENTAL | CARDIAC & CARDIOVASCULAR SYSTEMS | FEASIBILITY | FOLLOW-UP | RANDOMIZED-TRIAL | INTRAMYOCARDIAL INJECTION | AUTOLOGOUS SKELETAL MYOBLASTS | TRANSPLANTATION | THERAPY | Dilated cardiomyopathy | ISCHEMIC-HEART FAILURE | Stem cells | ACUTE MYOCARDIAL-INFARCTION | DOUBLE-BLIND | Bone marrow cells
Journal Article
Experimental Biology and Medicine, ISSN 1535-3702, 7/2015, Volume 240, Issue 7, pp. 969 - 978
The development of new therapeutic strategies is necessary to reduce the worldwide social and economic impact of cardiovascular disease, which produces high...
human umbilical cord blood-derived endothelial cells | ischemic cardiomyopathy | cell therapy | Human umbilical cord-derived stromal cells | PROGENITOR CELLS | MEDICINE, RESEARCH & EXPERIMENTAL | HEART-FAILURE | MONONUCLEAR-CELLS | BONE-MARROW-CELLS | IMPROVES CARDIAC-FUNCTION | INTRAMYOCARDIAL INJECTION | MESENCHYMAL STEM-CELLS | RAT MODEL | TRANSPLANTATION | ACUTE MYOCARDIAL-INFARCTION | Rats, Wistar | Cell Separation | Humans | Endothelial Cells - transplantation | Rats | Male | Transplantation, Heterologous | Mesenchymal Stem Cell Transplantation - methods | Cord Blood Stem Cell Transplantation - methods | Animals | Flow Cytometry | Mesenchymal Stromal Cells | Fluorescent Antibody Technique | Myocardial Ischemia - surgery | Disease Models, Animal | Original Research
human umbilical cord blood-derived endothelial cells | ischemic cardiomyopathy | cell therapy | Human umbilical cord-derived stromal cells | PROGENITOR CELLS | MEDICINE, RESEARCH & EXPERIMENTAL | HEART-FAILURE | MONONUCLEAR-CELLS | BONE-MARROW-CELLS | IMPROVES CARDIAC-FUNCTION | INTRAMYOCARDIAL INJECTION | MESENCHYMAL STEM-CELLS | RAT MODEL | TRANSPLANTATION | ACUTE MYOCARDIAL-INFARCTION | Rats, Wistar | Cell Separation | Humans | Endothelial Cells - transplantation | Rats | Male | Transplantation, Heterologous | Mesenchymal Stem Cell Transplantation - methods | Cord Blood Stem Cell Transplantation - methods | Animals | Flow Cytometry | Mesenchymal Stromal Cells | Fluorescent Antibody Technique | Myocardial Ischemia - surgery | Disease Models, Animal | Original Research
Journal Article
European Heart Journal, ISSN 0195-668X, 8/2008, Volume 29, Issue 15, pp. 1911 - 1921
Aims In clinical studies on cell therapy for acute myocardial infarction (MI), cells are usually applied by intracoronary infusion with balloon (IC/B). To test...
Heart | Myocardial infarction | Organ distribution | Cell therapy | Intracoronary | Stem cells | Balloon | Bone marrow cells | Intramyocardial | Mononuclear cells | Pig | PROGENITOR CELLS | SURVIVAL | stem cells | balloon | STEM-CELLS | CARDIAC & CARDIOVASCULAR SYSTEMS | bone marrow cells | ANGIOGENESIS | REGENERATION | myocardial infarction | intramyocardial | heart | ENDOTHELIAL BARRIER | pig | NEONATAL RAT CARDIOMYOCYTES | TRANSPLANTATION | mononuclear cells | THERAPY | cell therapy | intracoronary | organ distribution | Coronary Angiography | Microscopy, Confocal | Myocardial Infarction - therapy | Animals | Bone Marrow Cells - cytology | Swine | Male | Tomography, Emission-Computed | Injections, Intra-Arterial - methods | Bone Marrow Transplantation - methods | Myocardial Reperfusion - methods | Balloon Occlusion - methods
Heart | Myocardial infarction | Organ distribution | Cell therapy | Intracoronary | Stem cells | Balloon | Bone marrow cells | Intramyocardial | Mononuclear cells | Pig | PROGENITOR CELLS | SURVIVAL | stem cells | balloon | STEM-CELLS | CARDIAC & CARDIOVASCULAR SYSTEMS | bone marrow cells | ANGIOGENESIS | REGENERATION | myocardial infarction | intramyocardial | heart | ENDOTHELIAL BARRIER | pig | NEONATAL RAT CARDIOMYOCYTES | TRANSPLANTATION | mononuclear cells | THERAPY | cell therapy | intracoronary | organ distribution | Coronary Angiography | Microscopy, Confocal | Myocardial Infarction - therapy | Animals | Bone Marrow Cells - cytology | Swine | Male | Tomography, Emission-Computed | Injections, Intra-Arterial - methods | Bone Marrow Transplantation - methods | Myocardial Reperfusion - methods | Balloon Occlusion - methods
Journal Article
Journal of Cardiovascular Medicine, ISSN 1558-2027, 04/2011, Volume 12, Issue 4, pp. 239 - 248
OBJECTIVELarge acute ST-elevation myocardial infarction (STEMI) sometimes leaves extensive ischemic damage despite timely and successful primary angioplasty....
stem cells | PET | myocardial infarction | STEM-CELLS | CARDIAC & CARDIOVASCULAR SYSTEMS | COLONY-STIMULATING FACTOR | INTRAMYOCARDIAL DELIVERY | BONE-MARROW-CELLS | ISCHEMIC-HEART-DISEASE | ENDOTHELIAL PROGENITOR CELLS | DOUBLE-BLIND | PRIMARY ANGIOPLASTY | LEFT-VENTRICULAR FUNCTION | INTRACORONARY INJECTION | Stem Cells - immunology | Angioplasty, Balloon, Coronary - instrumentation | Ventricular Function, Left | Humans | Middle Aged | Male | Positron-Emission Tomography | Recovery of Function | Antigens, CD - analysis | Time Factors | Bone Marrow Transplantation | Adult | Female | Stents | Coronary Circulation | Anterior Wall Myocardial Infarction - surgery | Echocardiography | Myocardium - pathology | Treatment Outcome | AC133 Antigen | Anterior Wall Myocardial Infarction - physiopathology | Stroke Volume | Anterior Wall Myocardial Infarction - therapy | Analysis of Variance | Italy | Anterior Wall Myocardial Infarction - diagnosis | Glycoproteins - analysis | Peripheral Blood Stem Cell Transplantation | Peptides - analysis
stem cells | PET | myocardial infarction | STEM-CELLS | CARDIAC & CARDIOVASCULAR SYSTEMS | COLONY-STIMULATING FACTOR | INTRAMYOCARDIAL DELIVERY | BONE-MARROW-CELLS | ISCHEMIC-HEART-DISEASE | ENDOTHELIAL PROGENITOR CELLS | DOUBLE-BLIND | PRIMARY ANGIOPLASTY | LEFT-VENTRICULAR FUNCTION | INTRACORONARY INJECTION | Stem Cells - immunology | Angioplasty, Balloon, Coronary - instrumentation | Ventricular Function, Left | Humans | Middle Aged | Male | Positron-Emission Tomography | Recovery of Function | Antigens, CD - analysis | Time Factors | Bone Marrow Transplantation | Adult | Female | Stents | Coronary Circulation | Anterior Wall Myocardial Infarction - surgery | Echocardiography | Myocardium - pathology | Treatment Outcome | AC133 Antigen | Anterior Wall Myocardial Infarction - physiopathology | Stroke Volume | Anterior Wall Myocardial Infarction - therapy | Analysis of Variance | Italy | Anterior Wall Myocardial Infarction - diagnosis | Glycoproteins - analysis | Peripheral Blood Stem Cell Transplantation | Peptides - analysis
Journal Article