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Journal of Molecular Biology, ISSN 0022-2836, 01/2015, Volume 427, Issue 1, pp. 3 - 30
Voltage-gated sodium channels (Na s) provide the initial electrical signal that drives action potential generation in many excitable cells of the brain, heart,... 
ion permeation | channel pharmacology | structural biology | voltage-gated sodium channel | channel gating | Physiological aspects | Analysis | Pharmacology
Journal Article
NATURE, ISSN 0028-0836, 03/2006, Volume 440, Issue 7083, pp. 484 - 489
Since its discovery, the ClC family of chloride channels has presented biophysicists with unexpected behaviours and unusual surprises. The latest of these is... 
TORPEDO ELECTROPLAX | CLC CL-CHANNELS | ANION | CONSERVATION | MULTIDISCIPLINARY SCIENCES | CYSTEINE ACCESSIBILITY | MUSCLE | CONDUCTION | ION PERMEATION | PORES | SELECTIVITY
Journal Article
Journal of Physical Chemistry B, ISSN 1520-6106, 04/2018, Volume 122, Issue 16, pp. 4407 - 4417
Calcium release-activated calcium (CRAG) channels open upon depletion of Ca2+ from the endoplasmic reticulum, and when open, they are permeable to a selective... 
STIM | INTERFACE | PORE | STORE | CHEMISTRY, PHYSICAL | ION PERMEATION | MUTATIONS | PROTEINS | IDENTIFICATION | CRAC CHANNEL | SOFTWARE NEWS | Index Medicus
Journal Article
Journal Article
Chemistry Letters, ISSN 0366-7022, 3/2018, Volume 47, Issue 3, pp. 292 - 295
We demonstrate the effects of the layer distance and amounts of oxygen functional groups on ion permeation through a graphene oxide (GO) membrane. The Cu2+... 
Ion permeation | Layer distance | Graphene oxide | TRANSPORT | SEPARATION | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Physical Review E - Statistical, Nonlinear, and Soft Matter Physics, ISSN 1539-3755, 03/2008, Volume 77, Issue 3, pp. 031131 - 031131
Ion transport in biological and synthetic nanochannels is characterized by phenomena such as ion current fluctuations and rectification. Recently, it has been... 
OMPF | CHANNEL | PHYSICS, FLUIDS & PLASMAS | PORE | BARRIER | NANOTUBES | ION PERMEATION | CURRENTS | ELECTRODIFFUSION THEORY | PHYSICS, MATHEMATICAL | SELECTIVITY | BROWNIAN DYNAMICS
Journal Article
Nature Nanotechnology, ISSN 1748-3387, 2011, Volume 6, Issue 12, pp. 798 - 802
Journal Article
Journal of Chemical Theory and Computation, ISSN 1549-9618, 11/2007, Volume 3, Issue 6, pp. 2034 - 2045
A consistent treatment of electrostatic energies is arguably the most important requirement for the realistic modeling of biological systems. An important part... 
FREE-ENERGY CALCULATIONS | IRON-SULFUR PROTEINS | SOLVATION FREE-ENERGIES | ELECTRON-TRANSFER | PROTON-TRANSFER PATHWAYS | TRIOSEPHOSPHATE ISOMERASE | AQUAPORIN WATER CHANNELS | KCSA POTASSIUM CHANNEL | ION PERMEATION | MOLECULAR-DYNAMICS SIMULATIONS | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Biophysical Journal, ISSN 0006-3495, 11/2018, Volume 115, Issue 10, pp. 1920 - 1930
Voltage-gated sodium channels undergo transitions between open, closed, and inactivated states, enabling regulation of the translocation of sodium ions across... 
MOLECULAR-DYNAMICS | TRANSPORT | PROTEIN | BIOPHYSICS | CRYSTAL-STRUCTURE | CONDUCTION | ION PERMEATION | MODEL | SIMULATION | SELECTIVITY | NACHBAC | Medical research | Crystals | Molecular dynamics | Medicine, Experimental | Sensors | Structure | Molecular biology | Index Medicus
Journal Article
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, ISSN 0002-7863, 03/2016, Volume 138, Issue 9, pp. 3066 - 3075
Cl-/H+ transporters of the CLC superfamily form a ubiquitous class of membrane proteins that catalyze stoichiometrically coupled exchange of Cl- and H+ across... 
D-PATHWAY | CLC CHLORIDE CHANNELS | WATER CLUSTER | SUBSTRATE-BINDING | PORE DIMENSIONS | PROKARYOTIC HOMOLOG | MEMBRANE-PROTEIN | TRANSPORT CYCLE | ION PERMEATION | ANTIPORTER | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
by Hu, GD and Cao, ZX and Xu, SC and Wang, W and Wang, JH
SCIENTIFIC REPORTS, ISSN 2045-2322, 11/2015, Volume 5
The 14-3-3 sigma proteins are a family of ubiquitous conserved eukaryotic regulatory molecules involved in the regulation of mitogenic signal transduction,... 
DRUG | STEERED MOLECULAR-DYNAMICS | INTEGRATION | STRUCTURAL BASIS | MULTIDISCIPLINARY SCIENCES | HIV-1 PROTEASE | ION PERMEATION | SIMULATIONS | IDENTIFICATION | SELECTIVITY | 14-3-3-PROTEINS
Journal Article
JOURNAL OF GENERAL PHYSIOLOGY, ISSN 0022-1295, 03/2018, Volume 150, Issue 3, pp. 475 - 489
Mutations of Ca(V)1.1, the pore-forming subunit of the L-type Ca2+ channel in skeletal muscle, are an established cause of hypokalemic periodic paralysis... 
SKELETAL-MUSCLE | PHYSIOLOGY | R528H | SODIUM-CHANNELS | CA2+ CHANNELS | MOUSE MODEL | HYPOKALEMIC PERIODIC PARALYSIS | ION PERMEATION | VOLTAGE-SENSOR MUTATIONS | K+ CHANNEL | DIIS4 MUTATIONS
Journal Article
JOURNAL OF PHYSICS-CONDENSED MATTER, ISSN 0953-8984, 07/2018, Volume 30, Issue 29
Discrete state models of single-file ion permeation through a narrow ion channel pore are employed to analyze the ratio of forward to backward tracer current.... 
ion permeation | DISCRETE-STATE REPRESENTATION | PHYSICS, CONDENSED MATTER | flux ratio | STEADY-STATES | FORCE | ion channel | POTASSIUM CHANNELS | ENERGETICS | FLUCTUATION THEOREM | GRAMICIDIN | PERMEATION
Journal Article
Photochemical and Photobiological Sciences, ISSN 1474-905X, 2019, Volume 18, Issue 6, pp. 1471 - 1478
We conducted photo-activated delivery of drugs based on the fusion of liposomes with endocytic membranes, thus allowing the direct release of encapsulated... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | DOXORUBICIN | CHEMISTRY, PHYSICAL | PHOTOINDUCED DESTABILIZATION | RELEASE | CANCER | IN-VITRO | BIOPHYSICS | MEDIATED ENDOCYTOSIS | UP-CONVERSION NANOPARTICLES | ION PERMEATION | GIANT VESICLES | PHOTOCONTROL
Journal Article
Cell, ISSN 0092-8674, 05/2019, Volume 177, Issue 5, pp. 1252 - 1261.e13
Mitochondrial calcium uptake is crucial to the regulation of eukaryotic Ca homeostasis and is mediated by the mitochondrial calcium uniporter (MCU). While MCU... 
calcium channel | mitochondrial calcium uniporter | intracellular calcium signaling | HOMEOSTASIS | DETERMINANTS | MEMBRANE | BIOCHEMISTRY & MOLECULAR BIOLOGY | VALIDATION | GATEKEEPER | CHANNELS | ION PERMEATION | MICU1 | SELECTIVITY | MCU | CELL BIOLOGY | Physiological aspects | Calcium channels | Cells
Journal Article