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Journal Article
Oncogene, ISSN 0950-9232, 03/2013, Volume 32, Issue 10, pp. 1223 - 1232
Kaposi's sarcoma-associated herpesvirus (KSHV) K13/vFLIP (viral Flice-inhibitory protein) induces transcription of numerous genes through NF-kappa B... 
AIDS | endothelial cells | KSHV | Kaposi's sarcoma | NF-kB | vFLIP/K13 | KSHV VFLIP | IKK-GAMMA | ENZYME A20 | BIOCHEMISTRY & MOLECULAR BIOLOGY | DEPENDENT GENE-EXPRESSION | A20 INTERACTS | CELL BIOLOGY | KINASE COMPLEX | UBIQUITIN CHAINS | NF-kappa B | ONCOLOGY | ENDOTHELIAL-CELLS | GENETICS & HEREDITY | ZINC-FINGER PROTEIN | TRANSCRIPTION FACTOR | Sarcoma, Kaposi - metabolism | Humans | NF-kappa B - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Viral Proteins - metabolism | DNA-Binding Proteins - metabolism | Transfection | Herpesvirus 8, Human - metabolism | Nuclear Proteins - biosynthesis | Tumor Necrosis Factor alpha-Induced Protein 3 | Nuclear Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | NF-kappa B - antagonists & inhibitors | Transduction, Genetic | Endothelial Cells - metabolism | Viral Proteins - genetics | Herpesvirus 8, Human - genetics | Nuclear Proteins - metabolism | Viral Proteins - antagonists & inhibitors | Sarcoma, Kaposi - virology | DNA-Binding Proteins - genetics | Intracellular Signaling Peptides and Proteins - biosynthesis | Sarcoma, Kaposi - pathology | Proteins - genetics | Animals | Proteins - metabolism | NF-kappa B - genetics | Endothelial Cells - cytology | Chemokine CXCL10 - secretion | Mice | Chemokine CXCL10 - metabolism | DNA-Binding Proteins - biosynthesis | Sarcoma, Kaposi - genetics | Index Medicus | Cell proliferation | Cytokines | Transcription | Inflammation | regulatory proteins | IKK1 protein | Endothelial cells | FLICE-inhibitory protein | NF- Kappa B protein | Transcription activation | IP-10 protein | Chemokines | Tumors
Journal Article
The Lancet Infectious Diseases, ISSN 1473-3099, 2016, Volume 17, Issue 4, pp. 431 - 440
Journal Article
Journal Article
BMC Microbiology, ISSN 1471-2180, 08/2017, Volume 17, Issue 1, pp. 187 - 187
Background: The bronchial epithelium serves as the first defendant line of host against respiratory inhaled pathogens, mainly through releasing chemokines... 
PepO | BEAS-2B | Il-8 | IP-10 | IMMUNE-RESPONSE | DEFENSE | INNATE | NEUTROPHILS | MICROBIOLOGY | FACTOR-KAPPA-B | COLONIZATION | PNEUMOLYSIN | INTERLEUKIN-8 | RESISTANCE | PNEUMOCOCCAL PNEUMONIA | Interleukin-8 - genetics | Phosphorylation | Epithelial Cells - metabolism | Epithelial Cells - drug effects | Humans | eIF-2 Kinase - drug effects | Phosphatidylinositol 3-Kinases | Streptococcus pneumoniae - pathogenicity | Time Factors | Streptococcus pneumoniae - metabolism | Bronchi - metabolism | Transcription, Genetic | p38 Mitogen-Activated Protein Kinases - metabolism | Interleukin-8 - metabolism | Recombinant Proteins - metabolism | Cell Line | Cytokines - metabolism | Metalloendopeptidases - administration & dosage | Toll-Like Receptor 2 - metabolism | Toll-Like Receptor 4 - metabolism | Virulence Factors | Bacterial Proteins - administration & dosage | Gene Expression Regulation, Enzymologic | Bacterial Proteins - pharmacology | Signal Transduction - drug effects | Chemokine CXCL10 - genetics | Metalloendopeptidases - pharmacology | NF-KappaB Inhibitor alpha - metabolism | Mitogen-Activated Protein Kinase Kinases - drug effects | Chemokine CXCL10 - metabolism | Polysaccharides | Pneumonia | Interleukins | Bacterial pneumonia | B cells | Biological response modifiers | Streptococcus pneumoniae | Cell culture | Pathogenesis | Epithelial cells | Virulence | Interleukin | AKT protein | Kinases | Recruitment | Streptococcus infections | Proteins | Virulence factors | Lymphocytes | Toll-like receptors | IP-10 protein | Interleukin 8 | Surface protein A | Saccharides | Enzymes | Pathogens | Cytokines | Incubation | Dendritic cells | Peptidoglycans | Neutrophils | MAP kinase | Pharmacology | Inflammation | Protein A | PspA protein | TLR4 protein | Epithelium | Chromatography | 1-Phosphatidylinositol 3-kinase | Studies | Pneumolysin | Streptococcus | Inhibitors | TLR2 protein | Endopeptidase | Ligands | Interferon | Chemokines | Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2018, Volume 13, Issue 5, pp. e0197491 - e0197491
Toll-like receptors (TLRs) recognize the conserved molecular patterns in microorganisms and trigger myeloid differentiation primary response 88 (MyD88) and/or... 
Muscle Proteins - deficiency | NF-kappa B - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Interferon Regulatory Factor-7 - genetics | RNA, Messenger - metabolism | Adaptor Proteins, Vesicular Transport - metabolism | Intracellular Signaling Peptides and Proteins - deficiency | Pseudomonas aeruginosa - metabolism | Muscle Proteins - metabolism | Response Elements - genetics | Phosphorylation - drug effects | Toll-Like Receptors - metabolism | Neutrophil Infiltration - drug effects | Mice, Inbred C57BL | RNA, Messenger - genetics | Down-Regulation - drug effects | Enzyme Activation - drug effects | Interferon Regulatory Factor-7 - metabolism | Up-Regulation - drug effects | Macrophages - metabolism | Animals | Signal Transduction - drug effects | NF-KappaB Inhibitor alpha - metabolism | Lipopolysaccharides - pharmacology | Macrophages - drug effects | Chemokines - metabolism | Myeloid Differentiation Factor 88 - metabolism | Mitogen-Activated Protein Kinases - metabolism | Physiological aspects | Toll-like receptors | Genetic aspects | Interferon | Research | Calcineurin | Phosphorylation | RANTES | Infections | Regulatory sequences | Kinases | Macrophages | Lipopolysaccharides | Interleukin 6 | Proteins | Signal transduction | Receptors | Microorganisms | Immunology | Pathways | Lymphocytes | Rodents | Bone marrow | Fibroblasts | Pseudomonas aeruginosa | IP-10 protein | Tumor necrosis factor-TNF | Medical research | NF-κB protein | Immunoglobulins | Cytokines | Adapters | Leukocytes (neutrophilic) | TLR4 protein | Gene expression | Molecular chains | Immune systems | Interferon regulatory factor 7 | Pathology | Signaling | Molecular modelling | Tumor necrosis factor | MyD88 protein | Mice | Infiltration | Laboratory animals | Adapter proteins | Macrophage inflammatory protein | Chemokines | Cancer | Apoptosis | Index Medicus
Journal Article
Journal of Immunology, ISSN 0022-1767, 04/2002, Volume 168, Issue 7, pp. 3195 - 3204
IFN-gamma-inducible protein 10 (IP-10, CXCL10), a chemokine secreted from cells stimulated with type I and II IFNs and LPS, is a chemoattractant for activated... 
RESPONSE GENE | ALPHA-CHEMOATTRACTANT | DIFFERENTIAL EXPRESSION | MULTIPLE-SCLEROSIS | DENDRITIC CELLS | LYMPHOID ORGANS | CHEMOKINE RECEPTOR CXCR3 | ENDOTHELIAL-CELLS | CONTACT HYPERSENSITIVITY | CENTRAL-NERVOUS-SYSTEM | IMMUNOLOGY | CD8-Positive T-Lymphocytes - cytology | Encephalomyelitis - genetics | Spleen - immunology | Ovalbumin - immunology | Demyelinating Diseases - genetics | Demyelinating Diseases - virology | Interferon-gamma - metabolism | Lymphocyte Depletion | Cell Movement - genetics | Lymphocyte Culture Test, Mixed | CD4-Positive T-Lymphocytes - immunology | Cell Movement - immunology | Murine hepatitis virus - immunology | Lymphocyte Activation - genetics | Lymphocyte Activation - immunology | Dermatitis, Contact - prevention & control | Isoantigens - immunology | Demyelinating Diseases - immunology | Interferon-gamma - antagonists & inhibitors | Spleen - pathology | Growth Inhibitors - pharmacology | Dermatitis, Contact - genetics | Mutagenesis, Site-Directed | CD4-Positive T-Lymphocytes - cytology | Mice, Inbred C57BL | Coronavirus Infections - genetics | Chemokines, CXC - genetics | Demyelinating Diseases - prevention & control | Ovalbumin - pharmacology | Chemokines, CXC - deficiency | Coronavirus Infections - immunology | Down-Regulation - genetics | Chemokine CXCL10 | Mice, Knockout | Animals | Down-Regulation - immunology | Encephalomyelitis - immunology | Chemokines, CXC - physiology | Mice | Mice, Inbred BALB C | CD8-Positive T-Lymphocytes - immunology | Antigens - pharmacology | IP-10 protein | g-Interferon-inducible protein 10 | g-Interferon | CXCL10 protein | Index Medicus | Abridged Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2014, Volume 9, Issue 4, pp. e92325 - e92325
Astrocytes play a key role in maintenance of neuronal functions in the central nervous system by producing various cytokines,chemokines, and growth factors,... 
MICROGLIA | MULTIDISCIPLINARY SCIENCES | DISEASE | TRANSCRIPTION | MONOCYTE CHEMOATTRACTANT PROTEIN-1 | CENTRAL-NERVOUS-SYSTEM | IL-1-BETA | RECEPTORS | NF-KAPPA-B | EXPRESSION | BETA | Up-Regulation - drug effects | Astrocytes - drug effects | Tumor Necrosis Factor-alpha - pharmacology | Chemokines - secretion | Interleukin-1beta - pharmacology | Proteome - secretion | Signal Transduction - drug effects | Humans | Cells, Cultured | Down-Regulation - drug effects | Glial Fibrillary Acidic Protein - metabolism | Astrocytes - secretion | Physiological aspects | Genetic aspects | Research | Cytokines | Astrocytes | Chemokines | Brain | Neuroprotection | Multiple sclerosis | Genes | Central nervous system | Nervous system | Interleukin 1 receptors | Cerebrospinal fluid | Neuronal-glial interactions | Interleukin 6 | Proteins | Signal transduction | Neurotoxicity | Granulocyte colony-stimulating factor | IP-10 protein | Tumor necrosis factor-TNF | Lesions | Growth factors | Bioinformatics | Interleukin 8 | Medical research | NF-κB protein | Granulocyte-macrophage colony-stimulating factor | Interleukin 1 receptor antagonist | Fetuses | CCL3 protein | Inflammation | Gene expression | Neurological diseases | Medicine | Signaling | Protein arrays | Brain research | DNA microarrays | CXCL10 protein | Ligands | Alzheimers disease | Monocyte chemoattractant protein 1 | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2016, Volume 11, Issue 2, pp. e0149486 - e0149486
Dengue virus (DENV) infection causes organ injuries, and the liver is one of the most important sites of DENV infection, where viral replication generates a... 
PRO-INFLAMMATORY CYTOKINES | HEAT-SHOCK PROTEINS | D IMMUNE GLOBULIN | ISCHEMIA/REPERFUSION INJURY | ACTIVATED PROTEIN-KINASE | HEMORRHAGIC-FEVER | MULTIDISCIPLINARY SCIENCES | GAMMA-GLUTAMYL-TRANSFERASE | INHIBITOR SB203580 | TNF-ALPHA | CELL-DEATH | Liver - virology | Liver Diseases - virology | Male | Intracellular Signaling Peptides and Proteins - metabolism | Activating Transcription Factor 2 - metabolism | Liver - injuries | Animals | MAP Kinase Signaling System - drug effects | Liver - drug effects | Dengue Virus - pathogenicity | HSP27 Heat-Shock Proteins - metabolism | Liver Diseases - drug therapy | Mice | Mice, Inbred BALB C | p38 Mitogen-Activated Protein Kinases - metabolism | Imidazoles - therapeutic use | Phosphorylation - drug effects | Protein-Serine-Threonine Kinases - metabolism | Pyridines - therapeutic use | Complications and side effects | Liver failure | Care and treatment | Dengue | Heat shock proteins | Physiological aspects | Development and progression | Genetic aspects | Research | Mitogen-activated protein kinases | Phosphorylation | Transcription factors | RANTES | Liver | Viral diseases | Viruses | Infections | Kinases | Experiments | Caspase-3 | Interleukin 6 | Proteins | Histopathology | Rodents | IP-10 protein | Tumor necrosis factor-TNF | Activating transcription factor 2 | Vector-borne diseases | Thrombocytopenia | Cytokines | Hematology | Dengue fever | Caspase | MAP kinase | Tumor necrosis factor-α | Gene expression | Medicine | Caspase-8 | Injury prevention | Hospitals | Transaminases | Hsp27 protein | Interleukin 10 | Caspase-9 | Laboratory animals | Chemokines | Apoptosis | Index Medicus
Journal Article