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Hematology, ISSN 1024-5332, 10/2014, Volume 19, Issue 7, pp. 417 - 423
Objectives Thrombocytopenia is common in HIV-infected individuals and often requires a diagnostic bone marrow examination. Interpretation may, however, be... 
Immature platelet praction | Thrombocytopenia | Sysmex | HIV | IPF | however | a marginally significant positive association with ITP (P=0.059) | the limitations of morphological analysis in determining megakaryocyte function | ACTIVATION | eight HIV | 5000 | Conclusion: This study investigates the role of the IPF in HIV | linear regression analysis confirmed a significant independent inverse relationship between the IPF and | haematology analyzer and were correlated with bone marrow and other findings | platelet fraction (IPF) is a parameter which reportedly reflects megakaryocyte activity | 6.5%). Surprisingly | thrombocytopenia and the difficulty in assessing megakaryocyte function morphologically. The immature | thrombocytopenia (ITP) (median=16.3%) and low in 79% of patients with hypocellular marrow (median | respectively). Mulitivariate | and | INFECTION | therapy. Unexpectedly | HEMATOLOGY | be limited due to the multifactorial nature of HIV | it was highly variable among patients with malignant marrow infiltration and | platelet clearance due to HIV | ranging from 1.3 to 44%. It was raised in 78% of patients with immune | and emphasizes | DIAGNOSIS | but was unrelated to the CD4 count and exposure to antiretroviral | Objectives: Thrombocytopenia is common in HIV-infected individuals and often requires a diagnostic bone | Maxeke Johannesburg Academic Hospital. The IPF levels were measured using a Sysmex XE | association with the platelet count (P=0.0006) | driven platelet activation | RETICULATED PLATELETS | marrow examination. Interpretation may | marrow findings as well as other clinical variables of interest in South African patients with HIV | hypocellular marrow (P < 0.0001) | suggesting increased platelet production. The aim of this study was to correlate the IPF with the bone | Results: The median IPF was 7.6 | it showed a significant positive association with the HIV viral load (P | associated | mycobacterial infection of the bone marrow (BMTB) (median=8.4 and 7.1 | with an IPF > 7.7 | the absence of any relationship with malignant infiltration or BMTB. The IPF had a significant inverse | positive patients with thrombocytopenia were enrolled from the Charlotte | 0.005). We speculate this to reflect increased megakaryocyte activity in compensation for accelerated | associated thrombocytopenia | thrombocytopenia. Methods: Seventy | HIV Infections - blood | Multivariate Analysis | Bone Marrow Diseases - blood | Megakaryocyte Progenitor Cells - pathology | Cell Count | HIV Infections - virology | Humans | Linear Models | Male | Thrombocytopenia - virology | Thrombocytopenia - blood | Viral Load | Bone Marrow Diseases - virology | Megakaryocytes - pathology | Platelet Count | Adult | Female | South Africa
Journal Article
Cell Cycle, ISSN 1538-4101, 11/2019, Volume 18, Issue 22, pp. 3137 - 3146
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, irreversible and the most common fatal interstitial lung disease, which is characterized by... 
cytokine | tPA | proliferation | lung fibroblasts | Wnt/β-catenin | IPF
Journal Article
Chest, ISSN 0012-3692, 07/2017, Volume 152, Issue 1, pp. 103 - 112
Background Some patients with autoimmune characteristics and idiopathic interstitial pneumonia, particularly usual interstitial pneumonia (UIP), do not fit... 
interstitial pneumonia with autoimmune features | idiopathic pulmonary fibrosis | interstitial lung disease | autoimmune interstitial lung disease | CRITERIA | DIAGNOSIS | SCLERODERMA LUNG | PROGNOSIS | HEALTHY ELDERLY POPULATION | CONNECTIVE-TISSUE DISEASE | PREVALENCE | AUTOIMMUNE FEATURES | RESPIRATORY SYSTEM | LUNG-DISEASE | PULMONARY-FIBROSIS | CRITICAL CARE MEDICINE | Follow-Up Studies | Autoantibodies - blood | Humans | Middle Aged | Idiopathic Interstitial Pneumonias - diagnosis | Tomography, X-Ray Computed - methods | Male | Lung - diagnostic imaging | Statistics as Topic | Washington - epidemiology | Lung Diseases, Interstitial - diagnosis | Autoimmunity - immunology | Idiopathic Interstitial Pneumonias - physiopathology | Female | Lung Diseases, Interstitial - physiopathology | Needs Assessment | Connective Tissue Diseases - physiopathology | Diagnosis, Differential | Respiratory Function Tests - methods | Connective Tissue Diseases - diagnosis | Lung - physiopathology | Idiopathic Pulmonary Fibrosis - immunology | Idiopathic Interstitial Pneumonias - epidemiology | Lung Diseases, Interstitial - immunology | Idiopathic Pulmonary Fibrosis - diagnosis | Aged | Idiopathic Pulmonary Fibrosis - physiopathology | Cohort Studies | Idiopathic Interstitial Pneumonias - immunology | Autoantibodies | Pulmonary fibrosis | Health aspects | Analysis | Patient outcomes | Risk factors | UIP, usual interstitial pneumonia | IP, interstitial pneumonia | ILD, interstitial lung disease | UWMC, University of Washington Medical Center | PFT, pulmonary function test | CILD, Center for Interstitial Lung Diseases | AI-ILD, autoimmune interstitial lung disease | CTD, connective tissue disease | IPF, idiopathic pulmonary fibrosis | CTD-ILD, connective tissue disease-associated interstitial lung disease | NSIP, nonspecific interstitial pneumonia | IPAF, interstitial pneumonia with autoimmune features | Lone-IPF, IPF with negative CTD serologies | Dlco, diffusion capacity | Diffuse Lung Disease
Journal Article
Academic Radiology, ISSN 1076-6332, 01/2015, Volume 22, Issue 1, pp. 70 - 80
Rationale and Objectives: Median survival of patients with idiopathic pulmonary fibrosis (IPF) is 2-5years. Sensitive imaging metrics can play a role in... 
ILD | Quantitative lung fibrosis | CAD | Imaging biomarkers | Texture | IPF
Journal Article
JOURNAL OF CLINICAL MEDICINE, ISSN 2077-0383, 09/2016, Volume 5, Issue 9, p. 78
Idiopathic Pulmonary Fibrosis (IPF) now has two licensed treatments available. Pirfenidone was the first drug to be licensed and approved for use, followed by... 
SURVIVAL | MEDICINE, GENERAL & INTERNAL | MANAGEMENT | EFFICACY | pirfenidone | SAFETY | Idiopathic Pulmonary Fibrosis | nintedanib | CLINICAL-PRACTICE | IPF
Journal Article
Revue des Maladies Respiratoires, ISSN 0761-8425, 2019
Anti-PD1 immunotherapies have become an essential treatment for bronchial cancer. According to published studies, PD1 and PD-L1 inhibitors have a better... 
PD1 inhibitor | Immunotherapy | Lung cancer | Nivolumab | IPF
Journal Article
The Professional Geographer, ISSN 0033-0124, 07/2016, Volume 68, Issue 3, pp. 451 - 461
Journal Article
Current Respiratory Medicine Reviews, ISSN 1573-398X, 2015, Volume 10, Issue 4, pp. 241 - 244
Journal Article
Journal Article
ISIJ International, ISSN 0915-1559, 2018
In this paper, the characteristics of inclusions, microstructures and mechanical properties in non-quenched and tempered steel with Zr and Al addition were... 
ZrO2 | MnS precipitation | non-quenched and tempered steel | Al2O3 | IPF
Journal Article
Journal of clinical medicine, ISSN 2077-0383, 09/2019, Volume 8, Issue 9, p. 1447
Idiopathic pulmonary fibrosis (IPF) is the most common idiopathic interstitial pulmonary disease with a median survival of 3-5 years after diagnosis. Recent... 
idiopathic pulmonary fibrosis (IPF) | mucins | biomarkers
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 2005, Volume 15, Issue 6, pp. 1613 - 1617
We described herein the total synthesis and metabolism studies of 17,18,19,20- -iPF -III. The first total synthesis of 17,18,19,20- -iPF -III , a deuterated... 
Dinor-dihydro-iPF 2α-III | iPF 2α-III | Dinor-iPF 2α-III | Arachidonic acid | Metabolism | d4-iPF 2α-III | III | Dinor-iPF | iPF | Dinor-dihydro-iPF
Journal Article
Medical Physics, ISSN 0094-2405, 06/2017, Volume 44, Issue 6, pp. 2415 - 2428
Purpose Hyperpolarized 129Xe magnetic resonance imaging (MRI) using Dixon‐based decomposition enables single‐breath imaging of 129Xe in the airspaces,... 
thoracic cavity segmentation | image registration | PAH | hyperpolarized 129Xe MRI | binning | gas exchange | IPF | COPD | Image registration | Binning | Thoracic cavity segmentation | Xe MRI | Hyperpolarized | Gas exchange
Journal Article
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