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Molecular metabolism (Germany), ISSN 2212-8778, 02/2018, Volume 8, pp. 158 - 166
Journal Article
Journal of endocrinological investigation, ISSN 1720-8386, 07/2016, Volume 39, Issue 12, pp. 1365 - 1376
Journal Article
Journal Article
Journal Article
Journal Article
Biochemical journal, ISSN 1470-8728, 05/2005, Volume 388, Issue 2, pp. 393 - 406
.... Grb10 and Grb14, in particular, have been implicated in the regulation of insulin receptor signalling, whereas Grb7 appears predominantly to be involved in focal adhesion kinase-mediated cell migration... 
Cell signalling | Type II diabetes | Tyrosine kinase | Cell growth | Adapter protein | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Protein Structure, Tertiary | Proteins - physiology | Genetic Predisposition to Disease | Insulin - physiology | Humans | Gene Expression Regulation | Structure-Activity Relationship | Amino Acid Motifs | Animals | GRB10 Adaptor Protein | Protein Isoforms | Protein Conformation | Proteins - chemistry | Index Medicus | adapter protein | PI3K, phosphoinositide 3-kinase | SRS, Silver–Russell syndrome | tyrosine kinase | MEK1, MAP kinase | cell growth | BPS, between the PH and SH2 (domains) | Review | IGFR, IGF-I receptor | IRS, IR substrate | PDGF(-BB), platelet-derived growth factor(-BB) | UTR, untranslated region | RA, Ras-association | VEGF(R2), vascular endothelial growth factor (receptor 2) | Meg, maternally expressed gene | GIGYF protein, Grb10 interacting GYF protein | IUP, intrinsically unstructured protein | TZD, thiazolidinedione | ZIP, PKCζ-interacting protein | Erk, extracellular-signal-regulated kinase | IR, insulin receptor | Grb, growth factor receptor-bound protein | FGF(R), fibroblast growth factor receptor | GST, glutathione S-transferase | FAK, focal adhesion kinase | Shc, Src homology collagen | EGF(R), epidermal growth factor (receptor) | GM, Grbs and Mig | PDK-1, 3′-phosphoinositide-dependent kinase 1 | siRNA, small interfering RNA | PH, pleckstrin homology | PKCζ, protein kinase Cζ | cell signalling | APS, adapter protein with PH and SH2 domains | SH2, Src homology 2 | IGF-I, type I insulin-like growth factor | GK, Goto-Kakizaki | (m)UPD7, (maternal) uniparental disomy of chromosome 7 | MAPK, mitogen-activated protein kinase | Erk kinase | Nedd4, neuronal precursor cell-expressed developmentally down-regulated | PTP, protein tyrosine phosphatase
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 09/2007, Volume 13, Issue 18, pp. 5549s - 5555s
.... The insulin-like growth factor-I receptor (IGF-IR) is overexpressed in many types of solid and hematopoietic malignancies, and has been implicated as a principal cause of heightened proliferative and survival signaling... 
A12 | cancer | IGF-IR | insulin-like growth factor-I receptor | monoclonal antibody | IMC-A12 | Neoplasms - metabolism | Antibody Specificity | Neoplasms - therapy | Immunoglobulin G - immunology | Neoplasms - immunology | Humans | Receptor, IGF Type 1 - immunology | Immunoglobulin G - therapeutic use | Antibodies, Monoclonal - therapeutic use | Clinical Trials as Topic | Antibodies, Monoclonal - immunology | Index Medicus
Journal Article
Breast cancer research : BCR, ISSN 1465-542X, 07/2013, Volume 15, Issue 4, pp. R55 - R55
Journal Article