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FEBS Letters, ISSN 0014-5793, 1998, Volume 425, Issue 1, pp. 112 - 116
Journal Article
BMC Molecular Biology, ISSN 1471-2199, 03/2018, Volume 19, Issue 1, pp. 5 - 9
Background: BATF family transcription factors (BATF, BATF2 and BATF3) form hetero-trimers with JUNB and either IRF4 or IRF8 to regulate cell fate in T cells... 
Specificity | Transcription factors | IRF | JUNB | BATF | TRANSFORMATION | BINDING-SPECIFICITY | LEUCINE-ZIPPER | RECOGNITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | AP-1 | MNT PROTEIN | AFFINITY | REPRESSOR | B-ATF
Journal Article
Journal Article
International Immunopharmacology, ISSN 1567-5769, 11/2013, Volume 17, Issue 3, pp. 638 - 650
Neutrophils play a critical role in the host defense against bacterial and fungal infections, but their inappropriate activation also contributes to tissue... 
Signaling | Receptors | Inflammation | Kinases | Neutrophils | ACTIVATED PROTEIN-KINASE | COLONY-STIMULATING FACTOR | LEUKOCYTE ADHESION DEFICIENCY | IMMUNOLOGY | SRC-FAMILY KINASES | HUMAN POLYMORPHONUCLEAR LEUKOCYTES | HIGH-AFFINITY RECEPTOR | TUMOR-NECROSIS-FACTOR | TOLL-LIKE RECEPTORS | PHARMACOLOGY & PHARMACY | BETA-GAMMA-SUBUNITS | NF-KAPPA-B | Signal Transduction - immunology | Animals | Receptors, Cell Surface - immunology | Humans | Neutrophils - immunology | Selectins - immunology | Mycoses | Lectins | Fc receptors | Integrins | FcR, Fc-receptor | GPI, glycosylphosphatidylinositol anchor | CLEC, C-type lectin | OSCAR, osteoclast-associated receptor | PKB, protein kinase B | DAG, diacyl-glycerol | Tyk2, tyrosine protein kinase 2 | VCAM-1, vascular cell adhesion molecule 1 | ICAM-1, intercellular adhesion molecule 1 | FADD, Fas-associated protein with death domain | IκB, inhibitor of NF-κB | GM-CSF, granulocyte | MyD88, myeloid differentiation protein 88 | TNF, tumor necrosis factor | LTβ, lymphotoxin β | TRADD, TNFR1-associated death domain protein | Abl, Abelson leukemia proto-oncogene | SLP-76, SH2 domain-containing leukocyte protein of 76 kDa | CALDAG-GEFI, calcium and DAG-regulated guanine nucleotide exchange factor I | IL, interleukin | Src, Rous sarcoma virus proto-oncogene | IRF, IFN regulatory factor | RIG, retinoic acid-inducible gene | PLC, phospholipase C | TCR, T-cell receptor | IKK, IκB kinase | ITAM, immunoreceptor tyrosine-based activation motif | CARD, caspase activation and recruitment domain | IP3, inositol-tris-phosphate | CHO, Chinese hamster ovary cells | MKK, MAP kinase kinase | fMLP, formly-Met-Leu-Phe | TRAF, TNF receptor-associated factor | MIP, macrophage inflammatory protein | Rac, Ras-related C3 botulinum toxin substrate | monocyte colony-stimulating factor | PIP3, phosphatidylinositol-3-phosphate | VLA-4, very late antigen 4 (α4β1 integrin) | PAF, platelet activating factor | STAT, signal transducer and activator of transcription | TAK, TGFβ-activated kinase 1 | Mac-1, macrophage antigen 1 (αMβ2 integrin) | FcRγ, Fc-receptor γ-chain | Asc, apoptosis-associated speck-like protein containing a CARD | cIAP, cellular inhibitor of apoptosis | BCR, B-cell receptor | Fgr, Gardner–Rasheed feline sarcoma proto-oncogene | VASP, vasodilator-stimulated phosphoprotein | Hck, hematopoietic cell kinase | TGFβ, transforming growth factor β | Rap, Ras-related protein | SHP-1, SH2 domain-containing protein tyrosine phosphatase 1 | Syk, spleen tyrosine kinase | GPCR, G protein-coupled receptor | G-CSF, granulocyte colony-stimulating factor | TREM, triggering receptor expressed on myeloid cells | DISC, death-inducing signaling complex | MDL-1, myeloid DAP12-associating lectin 1 | C3G, Crk SH3 domain-binding guanine nucleotide exchange factor (RapGEF1) | NF-κB, nuclear factor κB | ERM, ezrin-radixin-moesin | Epac1, exchange protein activated by cyclic AMP 1 | LTB4, leukotriene B4 | Mcl, macrophage C-type lectin | SAP130, Sin3A-associated protein of 130 kDa | SH2, Src-homology 2 domain | MAP kinase, mitogen-activated protein kinase | PSGL-1, P-selectin glycoprotein ligand | PI3K, phoshoinositide-3-kinase | ADAP, adhesion and degranulation promoting adapter protein (Fyb, SLAP-130) | NLRP3, NOD-like receptor family, pyrin domain containing 3 | MDA5, melanoma differentiation-associated protein 5 | TLR, Toll-like receptor | GRK, GPCR kinase | LAD, leukocyte adhesion deficiency | MAPKAP-kinase, MAP kinase-associated protein kinase | ZAP-70, ζ-chain-associated protein of 70 kDa | TRAIL, TNF-related apoptosis-inducing ligand | JNK, c-Jun N-terminal kinase | LFA-1, lymphocyte function-associated receptor 1 (αLβ2 integrin) | ROS, reactive oxygen species | RIP3, receptor-interacting serine-threonine protein kinase 3 | DAP12, DNAX activating protein 12 | IFN, interferon | PIR, paired immunoglobulin-like receptor | PKC, protein kinase C | PAK, p21-activated kinase | ESL-1, E-selectin ligand 1 | GAP, GTPase activating protein | ERK, extracellular signal-regulated kinase | SOCS, suppressor of cytokine signaling | JAK, Janus kinase | RANK, receptor activator of NF-κB | IRAK, IL-1 receptor-associated kinase | NOD, nucleotide-binding oligomerization domain containing protein | CEACAM3, carcinoembryonic antigen-related cell adhesion molecule 3 (CD66b)
Journal Article
Cell, ISSN 0092-8674, 05/2018, Volume 173, Issue 4, pp. 920 - 933.e13
Inflammasome activation is critical for host defenses against various microbial infections. Activation of the NLRC4 inflammasome requires detection of... 
Salmonella | ICSBP | NLR | inflammasome | IRF8 | NLRC4 | Burkholderia | caspase-1 | PU.1 | NAIP | IFN | AIM2 INFLAMMASOME | INNATE IMMUNE RECOGNITION | GASDERMIN D | DENDRITIC CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BACTERIAL LIGANDS | GENE-EXPRESSION | FACTOR-I | SEQUENCE-BINDING-PROTEIN | DIFFERENTIAL ROLES | CELL BIOLOGY | Inflammasomes - metabolism | Interferon Regulatory Factors - antagonists & inhibitors | Neuronal Apoptosis-Inhibitory Protein - genetics | Interferon Regulatory Factors - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein - genetics | Pseudomonas aeruginosa - pathogenicity | RNA Interference | Flagellin - metabolism | Apoptosis Regulatory Proteins - genetics | Transcription, Genetic | Electrophoretic Mobility Shift Assay | Macrophages - microbiology | Calcium-Binding Proteins - metabolism | Promoter Regions, Genetic | Pyroptosis | Cytokines - metabolism | Salmonella typhimurium - pathogenicity | NLR Family, Pyrin Domain-Containing 3 Protein - metabolism | Cells, Cultured | Interferon Regulatory Factors - genetics | Macrophages - cytology | Neuronal Apoptosis-Inhibitory Protein - metabolism | Apoptosis Regulatory Proteins - metabolism | Macrophages - metabolism | Animals | Protein Binding | Mice | Calcium-Binding Proteins - genetics | RNA, Small Interfering - metabolism | Interferon | Bacterial infections | Genetic transcription | Biological response modifiers | infection | SPI1 | ALR | infectious diseases | immunity | Pseudomonas | type I interferon | interferon regulatory factor | pathogen | IRF
Journal Article
Human Vaccines & Immunotherapeutics, ISSN 2164-5515, 11/2014, Volume 10, Issue 11, pp. 3153 - 3164
DNA vaccination has emerged as an attractive immunotherapeutic approach against cancer due to its simplicity, stability, and safety. Results from numerous... 
cellular immune response | IRF, interferon regulatory factor | CTLs, cytotoxic lymphocytes | SCT, single-chain trimer | CEA, carcinoembryonic antigen | HER2, Her2/neu | phTERT, optimized full-length hTERT | DNA vaccines | PMED, particle mediated epidermal delivery | CIN, cervical intraepithelial neoplasia | hTERT, human telomerase reverse transcriptase | tumor antigens | TBK1, Tank-binding kinase 1 | HSP70, heat shock protein 70 | immune tolerance | STING, stimulator of interferon genes | APCs, antigen presenting cells | Id, idiotype | DOM, fragment c domain | NHP, non-human primate | Mam-A, Mammaglobin-A | EP, electroporation | humoral immune response | TAAs, tumor-associated antigens | MHC, major histocompatibility complex | Trp2, tyrosinase related protein 2 | CT antigens, cancer-testis antigens | TLRs, Toll-like receptors | IFNs, interferons | vaccine delivery | PSMA, prostate-specific membrane antigen | PAP, Prostatic acid phosphatase | TT, tetanus toxin | GITR, glucocorticoid-induced tumor necrosis factor receptor family-related genes | Humoral immune response | Vaccine delivery | Immune tolerance | Tumor antigens | Cellular immune response | tumor-associated antigens | SCT | MHC | tetanus toxin | major histocompatibility complex | IMMUNOLOGY | prostate-specific membrane antigen | TBK1 | phTERT | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | Mammaglobin-A | heat shock protein 70 | GENE-TRANSFER | CEA | neu | DOM | HSP70 | cancer-testis antigens | HUMAN TUMOR-ANTIGENS | CIN | PRESENTING CELLS | interferon regulatory factor | hTERT | IRF | human telomerase reverse transcriptase | tyrosinase related protein 2 | fragment c domain | INTRON SEQUENCE | GITR | CTLs |