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NATURE IMMUNOLOGY, ISSN 1529-2908, 08/2015, Volume 16, Issue 8, pp. 859 - 859
The receptor NLRP3 is involved in the formation of the NLRP3 inflammasome that activates caspase-1 and mediates the release of interleukin 1 beta (IL-1 beta)... 
CANCER-CELLS | FACTOR IRF4 | INTERLEUKIN-4 | ACTIVATION | RNA-SEQ | FACTOR-4 | HELPER-CELL-DIFFERENTIATION | GENE-EXPRESSION | IMMUNOLOGY | TUMOR-GROWTH | NALP3 INFLAMMASOME
Journal Article
NATURE IMMUNOLOGY, ISSN 1529-2908, 03/2015, Volume 16, Issue 3, pp. 267 - U227
The quality of the adaptive immune response depends on the differentiation of distinct CD4(+) helper T cell subsets, and the magnitude of an immune response is... 
TRANSCRIPTION FACTOR IRF4 | DENDRITIC CELLS | IMMUNE-RESPONSES | TOLERANCE | MOUSE | SCURFY | MICE | DIFFERENTIATION | IMMUNOLOGY | WNT | EXPRESSION
Journal Article
International Journal of Surgical Pathology, ISSN 1066-8969, 6/2019, Volume 27, Issue 4, pp. 372 - 379
Chronic endometritis is characterized by plasma cell (PC) infiltration of endometrial stroma. Identification of PCs can be challenging by routine hematoxylin... 
lymphocytes | IRF4 | MUM1 | CD138 | immunohistochemistry | plasma cells | chronic endometritis | SURGERY | LYMPHOMA-LIKE LESIONS | DIAGNOSIS | PATHOLOGY | MATURE B | HYSTEROSCOPY | CLONING | FACTOR LSIRF/IRF4 | EXPRESSION | REQUIREMENT
Journal Article
BLOOD, ISSN 0006-4971, 07/2019, Volume 134, Issue 2, pp. 171 - 185
The success of programmed cell death protein 1 (PD-1)/PD-L1-based immunotherapy highlights the critical role played by PD-L1 in cancer progression and reveals... 
PROTEIN | THERAPY | IRF4 | IMMUNOTHERAPY | MYC | KINASE | TRANSCRIPTION | INVOLVEMENT | HODGKIN LYMPHOMA | INDUCTION | HEMATOLOGY
Journal Article
BLOOD, ISSN 0006-4971, 06/2019, Volume 133, Issue 26, pp. 2776 - 2789
Anaplastic large cell lymphomas (ALCLs) represent a relatively common group of T-cell nonHodgkin lymphomas (T-NHLs) that are unified by similar pathologic... 
PATHOGENESIS | MUSCULIN | IRF4 | KINASE | LOOP | TUMOR | HELIX TRANSCRIPTION FACTOR | ABF-1 | GENE FUSION | HEMATOLOGY | EXPRESSION
Journal Article
Immunity, ISSN 1074-7613, 09/2017, Volume 47, Issue 3, pp. 481 - 497.e7
Transcriptional regulation during CD4 T cell fate decisions enables their differentiation into distinct states, guiding immune responses toward antibody... 
T effector cells | T cell receptor | Bcl6 | transcription factors | Irf4 | Blimp-1 | CD4 T cell differentiation | T follicular helper cells | antibody responses | CD4 T cell differentiation | REPRESSOR BCI6 | TRANSCRIPTION FACTOR IRF4 | EFFECTOR FUNCTION | IN-VIVO | EXPANSION | SPECIFICATION | IMMUNOLOGY | DISTINCT INFLUENCES | GENOMIC FEATURES | BINDING | DIFFERENTIAL EXPRESSION ANALYSIS | Interleukin-2 - metabolism | Cell Line | Immunization | T-Lymphocytes, Helper-Inducer - metabolism | Receptors, Antigen, T-Cell - metabolism | Signal Transduction | Humans | Gene Expression Regulation | Interferon Regulatory Factors - metabolism | Interferon Regulatory Factors - genetics | Male | Gene Expression Profiling | Gene Regulatory Networks | Mice, Knockout | Cell Differentiation - immunology | Animals | Nucleotide Motifs | T-Lymphocytes, Helper-Inducer - immunology | T-Lymphocytes, Helper-Inducer - cytology | Protein Binding | Antigens - immunology | Female | Mice | Binding Sites | T cells | Autoimmunity | Viral antibodies | Chromatin | Genes | Antibodies | DNA binding proteins | Cell differentiation | Transcription factors | Gene regulation | Helper cells | Signal strength | Lymphocytes T | Genomes | Regulatory sequences | Kinases | Recruitment | T-cell receptor | Cell fate | Lymphocytes | Rodents | Bioinformatics | Antigens | Immune response | Arbitration | Cytokines | Abundance | T cell receptors | Gene expression | CD4 antigen | Interferon regulatory factor 4 | Differentiation | Binding sites | Bcl-6 protein | Index Medicus
Journal Article
Frontiers in Immunology, 09/2019, Volume 10
Pre-clinical models and clinical trials demonstrate that targeting the action of the cytokine, granulocyte macrophage-colony stimulating factor (GM-CSF), can... 
pain | cell survival | inflammation | IRF4 | polarization | CCL17
Journal Article
NATURE REVIEWS IMMUNOLOGY, ISSN 1474-1733, 02/2018, Volume 18, Issue 2, pp. 121 - 133
T helper 2 (T(H)2) cells orchestrate protective type 2 immune responses, such as those that target helminths and facilitate tissue repair, but also contribute... 
RESPONSES IN-VIVO | SEVERE EOSINOPHILIC ASTHMA | TRANSCRIPTION FACTOR IRF4 | INDUCED ASTHMATIC RESPONSES | REGULATORY T-CELLS | ANTIGEN-PRESENTING CELLS | INNATE LYMPHOID-CELLS | ALLERGIC AIRWAY INFLAMMATION | IMMUNOLOGY | HOUSE-DUST MITE | THYMIC STROMAL LYMPHOPOIETIN
Journal Article
Journal Article
International Immunopharmacology, ISSN 1567-5769, 10/2019, Volume 75, pp. 105758 - 105758
The present study aimed to investigate the functional role of bortezomib in the development of acute allograft rejection (AR) after renal transplant. The mouse... 
Bortezomib | IRF4 | Allograft rejection | Proliferation | miR-15b | Differentiation | T follicular helper cells | Index Medicus
Journal Article
Journal of immunology (Baltimore, Md. : 1950), ISSN 0022-1767, 5/2015, Volume 194, Issue 10, pp. 4891 - 4900
Macrophages affect the magnitude and duration of inflammatory response in a functionally heterogeneous manner. The phenotype of macrophages is maintained... 
M2 macrophage markers | serum amyloid A | IRF4 | efferocytosis
Journal Article
Leukemia, ISSN 0887-6924, 2009, Volume 23, Issue 3, pp. 574 - 580
Journal Article
Journal Article
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 05/2019, Volume 202, Issue 10, pp. 3033 - 3040
Studies have demonstrated the importance of a GM-CSF -> IFN regulatory factor 4 (IRF4)-> CCL17 pathway, first identified in monocytes/macrophages, for... 
RESPONSES | COLONY-STIMULATING FACTOR | DENDRITIC CELLS | IRF4 | IN-VIVO | DYNAMICS | RECEPTOR | CHEMOKINE | IMMUNOLOGY | CCL17 | MHC CLASS-II
Journal Article
Journal Article
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