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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2015, Volume 112, Issue 35, pp. 11001 - 11006
Journal Article
NATURE REVIEWS GENETICS, ISSN 1471-0056, 05/2009, Volume 10, Issue 5, pp. 318 - 329
Studies using genome-wide platforms have yielded an unprecedented number of promising signals of association between genomic variants and human traits. This... 
UTTER REFUTATION | SYSTEMIC-LUPUS-ERYTHEMATOSUS | REGULATORY MOTIFS | FTO GENE | FUNDAMENTAL THEOREM | GENETICS & HEREDITY | SUSCEPTIBILITY LOCI | PROSTATE-CANCER RISK | GENE POLYMORPHISMS | IRF5 POLYMORPHISMS | COMPLEX DISEASE
Journal Article
Lupus, ISSN 0961-2033, 5/2019, Volume 28, Issue 6, pp. 740 - 747
Objective The aim of this study is to determine whether the functional interferon regulatory factor 5 (IRF5) polymorphism rs2004640 is associated with... 
IRF5 GENE | systemic lupus erythematosus | INCREASED RISK | BIAS | SUSCEPTIBILITY | meta-analysis | IRF5 | polymorphism | HAPLOTYPE | INDUCTION | RHEUMATOLOGY | EXPRESSION | Lupus | Ethnicity | Systemic lupus erythematosus | Alleles | Population | Population studies | Interferon | Minority & ethnic groups | Population genetics | Interferon regulatory factor | Meta-analysis | Polymorphism
Journal Article
International Reviews of Immunology, ISSN 0883-0185, 11/2018, Volume 37, Issue 5, pp. 229 - 248
Transcription factors are gene regulators that activate or repress target genes. One family of the transcription factors that have been extensively studied for... 
interferon regulatory factor 5 | transcription factor | immune cells | Autoimmune diseases | inflammatory disorders | DENDRITIC CELLS | TRANSCRIPTION FACTOR IRF5 | FACTOR 5 IRF5 | GENETIC-VARIANTS | INTERFERON-REGULATORY FACTOR | IMMUNOLOGY | B-CELLS | IFN-BETA | STRONG RISK-FACTOR | ANTIBODY-PRODUCTION | MACROPHAGE POLARIZATION
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 11/2018, Volume 9, p. 2622
The interferon regulatory factors (IRFs) are a family of master transcription factors that regulate pathogen-induced innate and acquired immune responses.... 
negative regulation | inhibition | IRF5 | positive regulation | autoimmunity | SYSTEMIC-LUPUS-ERYTHEMATOSUS | FACTOR 5 EXPRESSION | TRANSCRIPTION FACTOR IRF5 | CRYSTAL-STRUCTURE | IMMUNOLOGY | INTERFERON REGULATORY FACTOR | GENE POLYMORPHISM | PLASMACYTOID DENDRITIC CELLS | IFN-BETA | AUTOIMMUNE-DISEASE | EPSTEIN-BARR-VIRUS
Journal Article
Phytomedicine : international journal of phytotherapy and phytopharmacology, ISSN 0944-7113, 05/2019, Volume 62, p. 152976
Sedum sarmentosum Bunge extract (SSBE) has been used traditionally to treat liver inflammatory diseases in the Asian area. The aim of this study is to evaluate... 
Journal Article
Autoimmunity Reviews, ISSN 1568-9972, 2009, Volume 9, Issue 5, pp. A305 - A310
Abstract Sjogren's syndrome (SS) is a slowly progressing autoimmune disease, affecting predominantly middle-aged women, with a female to male ratio reaching... 
Allergy and Immunology | Therapy | Sjogren's syndrome | Clinical features | Differential diagnosis | Pathogenesis | Lymphoma | ACTIVATION | MIZORIBINE | DEFICIENT MICE | PREVALENCE | POLYMORPHISM | IMMUNOLOGY | INTERFERON | EPITHELIAL-CELLS | INTERLEUKIN-17 | IRF5 | CLASSIFICATION CRITERIA
Journal Article
by Feng, DD and Cao, Q and Zhang, DQ and Wu, XL and Yang, CX and Chen, YF and Yu, T and Qi, HX and Zhou, GP
ONCOTARGETS AND THERAPY, ISSN 1178-6930, 2019, Volume 12, pp. 6907 - 6915
Purpose: Lung cancer is the most common malignant tumor in the world, and its incidence and mortality are very high. This study focuses on the mechanism of... 
non-small cell lung cancer | TARGET | ONCOLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | E2F transcription factor 1 | interferon regulatory factor 5 | IRF5 | PROMOTER | E2F transcription factor 1 (E2F1) | interferon regulatory factor 5 (IRF5) | Non-small cell lung cancer (NSCLC)
Journal Article
PAIN, ISSN 0304-3959, 09/2018, Volume 159, Issue 9, pp. 1752 - 1763
Microglia-neuron signalling in the spinal cord is a key mediator of mechanical allodynia caused by peripheral nerve injury. We recently reported sex... 
Spinal cord | SPINAL MICROGLIA | Nerve injury | Rats | TACTILE ALLODYNIA | Sex differences | STRESS-INDUCED ANALGESIA | NEUROSCIENCES | P2X receptors | CLINICAL NEUROLOGY | Microglia | NEUROPATHIC PAIN | IMMUNE-SYSTEM | INHIBITION | ANION GRADIENT | ANESTHESIOLOGY | IRF5 | MICE | SEX-DIFFERENCES
Journal Article
Frontiers in immunology, ISSN 1664-3224, 2019, Volume 10, p. 199
Journal Article
by Lessard, Christopher J and Li, He and Adrianto, Indra and Ice, John A and Rasmussen, Astrid and Grundahl, Kiely M and Kelly, Jennifer A and Dozmorov, Mikhail G and Miceli-Richard, Corinne and Bowman, Simon and Lester, Sue and Eriksson, Per and Eloranta, Maija-Leena and Brun, Johan G and Gøransson, Lasse G and Harboe, Erna and Guthridge, Joel M and Kaufman, Kenneth M and Kvarnström, Marika and Jazebi, Helmi and Graham, Deborah S. Cunninghame and Grandits, Martha E and Nazmul-Hossain, Abu N. M and Patel, Ketan and Adler, Adam J and Maier-Moore, Jacen S and Farris, A. Darise and Brennan, Michael T and Lessard, James A and Chodosh, James and Gopalakrishnan, Rajaram and Hefner, Kimberly S and Houston, Glen D and Huang, Andrew J. W and Hughes, Pamela J and Lewis, David M and Radfar, Lida and Rohrer, Michael D and Stone, Donald U and Wren, Jonathan D and Vyse, Timothy J and Gaffney, Patrick M and James, Judith A and Omdal, Roald and Wahren-Herlenius, Marie and Illei, Gabor G and Witte, Torsten and Jonsson, Roland and Rischmueller, Maureen and Rönnblom, Lars and Nordmark, Gunnel and Ng, Wan-Fai and Mariette, Xavier and Anaya, Juan-Manuel and Rhodus, Nelson L and Segal, Barbara M and Scofield, R. Hal and Montgomery, Courtney G and Harley, John B and Sivils, Kathy L and UK Primary Sjogren's Syndrome Regi and UK Primary Sjögren's Syndrome Registry and for UK Primary Sjögren's Syndrome Registry and Linköpings universitet and Institutionen för klinisk och experimentell medicin and Reumatologiska kliniken i Östergötland and Hjärt- och Medicincentrum and Östergötlands Läns Landsting and Hälsouniversitetet and Reumatologi
Nature Genetics, ISSN 1061-4036, 11/2013, Volume 45, Issue 11, pp. 1284 - 1294
Journal Article
Frontiers in Oncology, ISSN 2234-943X, 10/2019, Volume 9
Solasonine (SS), a natural glycoalkaloid component, has been shown to have potent inhibitory activity and cytotoxicity against many cancer types. However, the... 
Genetic aspects | Hepatoma | Gene expression | Cancer | HCC | IRF5 | SP1 | solasonine | lncRNA CCAT1 | miR-375-3p
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2014, Volume 63, Issue 15, pp. 1556 - 1566
Journal Article