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NATURE IMMUNOLOGY, ISSN 1529-2908, 09/2019, Volume 20, Issue 9, pp. 1090 - 1092
Journal Article
Fish and Shellfish Immunology, ISSN 1050-4648, 11/2019, Volume 94, pp. 1 - 9
Interferon regulatory factor 8 (IRF8) increases type I IFN transcription levels by binding to IFN promoters, thereby playing a role in innate immunity.... 
IFNγ | IRF8 | Trachinotus ovatus | Transcription factor | Promoter activity | Index Medicus
Journal Article
Advances in Medical Sciences, ISSN 1896-1126, 09/2019, Volume 64, Issue 2, pp. 230 - 234
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system with a neurodegenerative compound. Heterogenetic background of autoimmunity... 
IRF8 | Multiple sclerosis | SNV | GPC5 | CD58 | Index Medicus
Journal Article
Journal Article
Journal of immunology (Baltimore, Md. : 1950), ISSN 0022-1767, 11/2011, Volume 187, Issue 9, pp. 4426 - 4430
A prominent phenotype of IRF8 knock out (IRF8 KO) mice is the uncontrolled expansion of immature myeloid cells. The molecular mechanism underlying this... 
Bax | Fas | IRF8 | Myeloid cell
Journal Article
Blood, ISSN 0006-4971, 04/2018, Volume 131, Issue 14, pp. 1587 - 1599
Monocytes and macrophages play a key role in defending pathogens, removing the dead cells or cell debris, and wound healing. The mammalian target of rapamycin... 
TRANSCRIPTION FACTOR IRF8 | DENDRITIC CELLS | YOLK-SAC | HEMATOPOIETIC STEM-CELLS | TISSUE-RESIDENT MACROPHAGES | RECEPTOR | MICE | DIFFERENTIATION | AUTOPHAGY | HEMATOLOGY | EFFECTOR-CELLS | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Autoimmunity, ISSN 0896-8411, 01/2019, Volume 96, pp. 113 - 122
The follicular helper T cell (T ) are established regulators of germinal center (GC) B cells, whether T have pathogenic potential independent of B cells is... 
IRF8 | Colitis | IRF4 | TFH | TRANSCRIPTION FACTORS | REGULATORY FACTOR FAMILY | IMMUNOLOGY | FH CELLS | IL-21 | B-CELLS | COOPERATE | COMMITMENT | BCL6 | EXPANSION | EXPRESSION
Journal Article
Journal of immunology (Baltimore, Md. : 1950), ISSN 0022-1767, 8/2015, Volume 195, Issue 4, pp. 1480 - 1488
Interferon regulatory factor 8 (IRF8) is constitutively expressed in monocytes and B cells and plays critical role in the functional maturation of microglia... 
experimental autoimmune uveitis | Uveitis | Interferon Regulatory Factor 8 | EAU | EAE | IRF8 | Neuroinflammation | Retina | Microglia
Journal Article
Immunity, ISSN 1074-7613, 09/2016, Volume 45, Issue 3, pp. 626 - 640
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 03/2019, Volume 139, Issue 3, pp. 605 - 614
The vast majority of polymorphisms for human dermatologic diseases fall in noncoding DNA regions, leading to difficulty interpreting their functional... 
PLASMACYTOID DENDRITIC CELLS | LUPUS | INTEGRATIVE ANALYSIS | IKAROS | IRF8 TRANSCRIPTION FACTOR | REGULATORY T-CELLS | STAT4 | TOFACITINIB | BET BROMODOMAIN INHIBITION | EXPRESSION | DERMATOLOGY
Journal Article
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, ISSN 1055-9965, 03/2013, Volume 22, Issue 3, pp. 461 - 466
Background: Our genome-wide association study (GWAS) of chronic lymphocytic leukemia (CLL) identified 4 highly correlated intronic variants within the IRF8... 
ONCOLOGY | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | POLYMORPHISMS | SNPs | IRF8 | CLL | NHL | risk locus
Journal Article