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Canadian Journal of Physiology and Pharmacology, ISSN 0008-4212, 02/2012, Volume 90, Issue 2, pp. 237 - 242
Journal Article
Journal of Ethnopharmacology, ISSN 0378-8741, 10/2019, Volume 243, p. 111966
decoction is a Chinese herbal formula with unique advantages for the treatment of type 2 diabetes mellitus (T2DM). The aim of the present study was to... 
Insulin resistance | miRNA | IRS1 | Insulin receptor signaling pathway | Yunpiheluo decoction
Journal Article
Journal Article
Trends in Endocrinology and Metabolism, ISSN 1043-2760, 11/2018, Volume 29, Issue 11, pp. 737 - 739
Mechanistic target of rapamycin complex (mTORC)1 is the major regulator of metabolism at the cellular and organismal level. mTORC1-mediated regulatory feedback... 
IGF-I | feedback loops | mTORC2 | IRS1 | mTORC1 | METABOLISM | ENDOCRINOLOGY & METABOLISM
Journal Article
Lipids, ISSN 0024-4201, 02/2019, Volume 54, Issue 2-3, pp. 141 - 148
In the current investigation, the effect of epigallocatechin gallate (EGCG) on the phosphorylation of IRS1 S307 and Akt S473 molecules in insulin‐resistant... 
Type 2 diabetes | S307 | IRS1 | Rosiglitazone | Akt | S473 | Epigallocatechin gallate (EGCG)
Journal Article
SCIENCE & SPORTS, ISSN 0765-1597, 06/2019, Volume 34, Issue 3, pp. E229 - E233
Objectives. Exercise is widely perceived to be an important component for diabetes. This study designed to evaluate the responses of different exercises... 
SPORT SCIENCES | Aerobic | IRS1 | Resistance training | PTP-1B | Diabetes | HIIT
Journal Article
Journal of Gastroenterology, ISSN 0944-1174, 12/2018, Volume 53, Issue 12, pp. 1261 - 1275
Nonalcoholic fatty liver disease (NAFLD) is a risk factor for type 2 diabetes. Our aim was to investigate the relationship between NAFLD and impaired glucose... 
Hyperinsulinemia | Insulin resistance | NAFLD | Postprandial hyperglycemia | IRS1 | Original —Liver, Pancreas, and Biliary Tract
Journal Article
Toxicological Sciences, ISSN 1096-6080, 07/2013, Volume 134, Issue 1, pp. 26 - 38
Journal Article
Journal Article
by Wu, L and Li, YF and Li, JY and Ma, DL
ONCOLOGY RESEARCH, ISSN 0965-0407, 2019, Volume 27, Issue 4, pp. 459 - 467
A large number of microRNAs (miRNAs) have been previously demonstrated to be dysregulated in breast cancer (BC), and alterations in miRNA expression may affect... 
Insulin receptor substrate 1 (IRS1) | miR-664 | METASTASIS | BIOGENESIS | ONCOLOGY | Breast cancer (BC) | GROWTH | Proliferation | EXPRESSION | Invasion
Journal Article
MOLECULAR AND CELLULAR BIOCHEMISTRY, ISSN 0300-8177, 07/2018, Volume 444, Issue 1-2, pp. 103 - 108
This study examined the hypothesis that 1,25-dihydroxyvitamin D-3 (1,25(OH)(2)D-3) upregulates the insulin-independent signaling cascade of glucose metabolism.... 
VITAMIN-D SUPPLEMENTATION | PHYSIOLOGY | IRS1 | KNOCKOUT MICE | SIRTUINS | SIRT1 | 3T3L1 ADIPOCYTES | CELL BIOLOGY | Glucose metabolism | Vitamin D | INSULIN-RESISTANCE | GLUT4 | CALORIE RESTRICTION
Journal Article
TRANSLATIONAL ONCOLOGY, ISSN 1936-5233, 02/2018, Volume 11, Issue 1, pp. 86 - 93
Malignant gliomas are the most common primary brain tumor and are characterized by rapid and highly invasive growth. Because of their poor prognosis, new... 
CELLS | MUTANTS | REPLICATION | PROTEIN | ONCOLOGY | RESECTION | GLIOMA | GROWTH | HUMAN CYTOMEGALOVIRUS IRS1 | INFECTION | NEUROVIRULENCE
Journal Article
FEBS Open Bio, ISSN 2211-5463, 05/2019, Volume 9, Issue 5, pp. 1008 - 1019
Panax notoginseng saponins ( PNS ) are a commonly used traditional medicine to treat diabetes in China. Recent studies have confirmed their anti‐diabetic... 
KKA | Panax notoginseng | signaling | GLUT | IRS1 | y mice | 3K | AKT | skeletal muscle | diabetes | saponins | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | GLUCOSE-TRANSPORT | MODEL | KKAy mice | LIPOTOXICITY | PATHOGENESIS | IRS1-PI3K-AKT signaling | OBESITY | Panax notoginseng saponins | GLUT4 | TYPE-2 | CELL
Journal Article
Tropical Journal of Pharmaceutical Research, ISSN 1596-5996, 01/2019, Volume 18, Issue 1, pp. 25 - 30
Purpose: To investigate the potential role of miR-126 in regulating the proliferation and cisplatin chemosensitivity of human hepatocellular carcinoma (HCC)... 
Chemosensitivity | HCC | miR-126 | IRS1 | Cisplatin | OVEREXPRESSION | REPAIR | GROWTH | PHARMACOLOGY & PHARMACY | cisplatin | chemosensitivity | EXPRESSION | CHEMOTHERAPY
Journal Article
American Journal of Cancer Research, ISSN 2156-6976, 2016, Volume 6, Issue 5, pp. 996 - 1010
Insulin resistance (IR) is an important mechanism of pathogenesis of endometrial cancer (EC) and explains the pathogenic mechanism of high risk factors... 
IRS1/2 | Endometrial cancer | YAP/TAZ | Insulin signaling | PROTEIN | MECHANISMS | DIABETES-MELLITUS | BREAST-CANCER | insulin signaling | INHIBITION | RISK-FACTOR | ONCOLOGY | ADIPONECTIN | endometrial cancer | RESISTANCE | CONSEQUENCES | GROWTH-FACTOR-I
Journal Article
Science et Sports, ISSN 0765-1597, 06/2019, Volume 34, Issue 3, pp. e229 - e233
Exercise is widely perceived to be an important component for diabetes. This study designed to evaluate the responses of different exercises (aerobic, HIIT,... 
Aérobie | Aerobic | IRS1 | Resistance training | Entraînement de résistance | Diabète | PTP-1B | Diabetes | HIIT
Journal Article
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