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Journal of Internal Medicine, ISSN 0954-6820, 05/2018, Volume 283, Issue 5, pp. 461 - 475
Journal Article
Journal Article
Journal of Cerebral Blood Flow & Metabolism, ISSN 0271-678X, 9/2012, Volume 32, Issue 9, pp. 1810 - 1819
Many neuroprotective agents have been effective in experimental stroke, yet few have translated into clinical application. One reason for this may be failure... 
risk factors | inflammation | cerebral ischemia | therapy | interleukin-1 receptor antagonist | neutroprotection | ARTERY OCCLUSION | PROTECTION | FOCAL CEREBRAL-ISCHEMIA | NEURONAL INJURY | EXPERIMENTAL STROKE | MECHANISMS | NEUROSCIENCES | SYSTEMIC INFECTION | MODELS | RECOMMENDATIONS | ENDOCRINOLOGY & METABOLISM | MICE | HEMATOLOGY | Immunohistochemistry | Recombinant Proteins - therapeutic use | Inflammation - pathology | Neuroprotective Agents | Stroke - complications | Male | Neutrophil Infiltration | Stroke - pathology | Inflammation - complications | Reperfusion | Inflammation - drug therapy | Infarction, Middle Cerebral Artery - drug therapy | Interleukin 1 Receptor Antagonist Protein - pharmacology | Ischemic Attack, Transient - pathology | Brain Ischemia - complications | Ischemic Attack, Transient - drug therapy | Microglia - drug effects | Rats | Treatment Outcome | Stroke - drug therapy | Infarction, Middle Cerebral Artery - pathology | Recombinant Proteins - pharmacology | Blood-Brain Barrier - drug effects | Interleukin 1 Receptor Antagonist Protein - pharmacokinetics | Magnetic Resonance Imaging | Animals | Interleukin 1 Receptor Antagonist Protein - therapeutic use | Lymphocyte Activation - drug effects | Brain Ischemia - drug therapy | Brain Ischemia - pathology | Brain - pathology | Cytokines - biosynthesis | Blood-brain barrier | Original
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2012, Volume 109, Issue 9, pp. 3317 - 3322
Inhibition of the ternary protein complex of the synaptic scaffolding protein postsynaptic density protein-95 (PSD-95), neuronal nitric oxide synthase (nNOS),... 
Receptors | Drug interactions | Plasma stability | Ligands | Brain damage | Oxides | Mice | Strokes | Blood brain barrier | Behavioral neuroscience | Protein-protein interactions | Drug discovery | Ischemic stroke | RECEPTOR INTERACTION | MULTIDISCIPLINARY SCIENCES | NEUROTOXICITY | protein-protein interactions | POTENT | drug discovery | DYNAMICS | MICE | LIGAND | CEREBRAL-ISCHEMIA | DOMAINS | BINDING | ischemic stroke | POSTSYNAPTIC DENSITY | Disks Large Homolog 4 Protein | Neuroprotective Agents - therapeutic use | Learning Disorders - prevention & control | Guanylate Kinases - antagonists & inhibitors | Humans | Molecular Sequence Data | Sensation Disorders - etiology | Crystallography, X-Ray | Male | Molecular Targeted Therapy | Learning Disorders - etiology | Movement Disorders - prevention & control | Neuroprotective Agents - pharmacology | Peptides - chemical synthesis | Infarction, Middle Cerebral Artery - complications | Drug Design | Nuclear Magnetic Resonance, Biomolecular | Infarction, Middle Cerebral Artery - drug therapy | Drug Evaluation, Preclinical | Binding Sites | PDZ Domains - drug effects | Amino Acid Sequence | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | Mice, Inbred C57BL | Models, Molecular | Infarction, Middle Cerebral Artery - pathology | Peptides - pharmacology | Neuroprotective Agents - chemical synthesis | Animals | Membrane Proteins - antagonists & inhibitors | Movement Disorders - etiology | Sensation Disorders - prevention & control | Protein Conformation | Peptides - therapeutic use | Postural Balance | Blood-Brain Barrier | Cellular proteins | Research | Neuroprotective agents | Drug therapy | Health aspects | Synapses | Biological Sciences | TEKNIKVETENSKAP | Engineering and Technology | Teknik och teknologier | TECHNOLOGY
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 11/2019
Journal Article
Stroke, ISSN 0039-2499, 07/2015, Volume 46, Issue 7, pp. 1956 - 1965
Journal Article
Circulation Research, ISSN 0009-7330, 03/2012, Volume 110, Issue 5, pp. 727 - 738
RATIONALE:Stroke is the third most common cause of death in industrialized countries. The main therapeutic target is the ischemic penumbra, potentially... 
ischemic penumbra | collateral blood flow | ischemic stroke | nitric oxide inhalation | CARDIAC & CARDIOVASCULAR SYSTEMS | PLATELET-AGGREGATION | FOCAL CEREBRAL-ISCHEMIA | S-NITROSOHEMOGLOBIN | FLOW | RESPIRATORY-DISTRESS-SYNDROME | L-ARGININE | SUBARACHNOID HEMORRHAGE | PERIPHERAL VASCULAR DISEASE | RED-BLOOD-CELLS | HEMATOLOGY | HYPOXIC PULMONARY VASOCONSTRICTION | Arterioles - physiology | Neurons - pathology | Nitric Oxide - pharmacology | Humans | Male | Nitric Oxide - therapeutic use | Stroke - physiopathology | Stroke - pathology | Brain - blood supply | Regional Blood Flow - drug effects | Models, Animal | Vasodilation - physiology | Cell Survival - physiology | Collateral Circulation - drug effects | Cell Survival - drug effects | Collateral Circulation - physiology | Stroke - prevention & control | Mice, Inbred C57BL | Administration, Inhalation | Brain Ischemia - physiopathology | Brain Ischemia - prevention & control | Nitric Oxide - administration & dosage | Arterioles - drug effects | Animals | Brain Ischemia - pathology | Sheep | Mice | Vasodilation - drug effects | Regional Blood Flow - physiology | Brain | Brain Ischemia | pathology | Arterioles | Collateral Circulation | Vasodilation | administration & dosage | pharmacology | Neurologi | Administration | Stroke | Cell Survival | Neurons | physiology | drug effects | prevention & control | Nitric Oxide | Regional Blood Flow | Inbred C57BL | Inhalation | Neurology | physiopathology | blood supply | Animal | Models | therapeutic use
Journal Article