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PLOS ONE, ISSN 1932-6203, 02/2019, Volume 14, Issue 2
Diabetic retinopathy (DR) is a common neurovascular complication of type 1 diabetes. Current therapeutics target neovascularization characteristic of end-stage... 
ISOMEROHYDROLASE | FENOFIBRATE | MULTIDISCIPLINARY SCIENCES | DOWN-REGULATION | MITOCHONDRIAL DYSFUNCTION | ALPHA | NEURODEGENERATION | MODEL | ENERGY-METABOLISM | DEFICITS | DEGENERATION
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 05/2008, Volume 358, Issue 21, pp. 2240 - 2248
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 05/2008, Volume 358, Issue 21, pp. 2231 - 2239
Journal Article
Lancet, The, ISSN 0140-6736, 2009, Volume 374, Issue 9701, pp. 1597 - 1605
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 10/2012, Volume 109, Issue 41, pp. E2747 - E2756
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 03/2019, Volume 9, Issue 1, pp. 5218 - 14
Association with the endoplasmic reticulum (ER) membrane is a critical requirement for the catalytic function of RPE65. Several studies have investigated the... 
RETINOID ISOMERASE | MICROSOMAL PROTEIN | ISOMEROHYDROLASE | MECHANISM | MULTIDISCIPLINARY SCIENCES | PURIFICATION | PSD-95 | EXPRESSION | PIGMENT-EPITHELIUM | Vitamin A | Lecithin | Palmitoylation | Post-translation | Acyltransferase | Endoplasmic reticulum | Visual perception
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2008, Volume 105, Issue 39, pp. 15112 - 15117
Journal Article
ACS CHEMICAL BIOLOGY, ISSN 1554-8929, 04/2016, Volume 11, Issue 4, pp. 1049 - 1057
Metazoan photochemistry involves cis-trans isomerization of a retinylidene chromophore bound to G protein coupled receptors. Successful production of... 
RETINOID ISOMERASE | VISUAL CYCLE | ISOMEROHYDROLASE | BETA-CAROTENE | ENZYME | METABOLISM | MECHANISM | PROVITAMIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | IDENTIFICATION | RPE65
Journal Article
Stem Cells, ISSN 1066-5099, 10/2009, Volume 27, Issue 10, pp. 2427 - 2434
Human induced pluripotent stem cells (iPSCs) have great promise for cellular therapy, but it is unclear if they have the same potential as human embryonic stem... 
Retinal pigmented epithelium | Age-related macular degeneration | Induced pluripotent stem cells | Retinitis pigmentosa | ISOMEROHYDROLASE | ROD OUTER SEGMENTS | PHAGOCYTOSIS | MACULAR DEGENERATION | retinal pigmented epithelium | IPS CELLS | CELL & TISSUE ENGINEERING | CELL BIOLOGY | MICROSOMAL PROTEIN | ONCOLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | retinitis pigmentosa | induced pluripotent stem cells | RPE CELLS | DIFFERENTIATION | HEMATOLOGY | age-related macular degeneration | EYE DEVELOPMENT | EXPRESSION | Retinal Pigment Epithelium - metabolism | Cell Proliferation | Homeodomain Proteins - metabolism | Humans | Nerve Tissue Proteins - analysis | Retinal Diseases - therapy | RNA, Messenger - analysis | Retinal Rod Photoreceptor Cells - metabolism | RNA, Messenger - metabolism | SOXB1 Transcription Factors - metabolism | SOXB1 Transcription Factors - pharmacology | Homeodomain Proteins - pharmacology | Cell Differentiation - physiology | Integrin alphaV - metabolism | Biomarkers - metabolism | Cell Line | Nanog Homeobox Protein | Pluripotent Stem Cells - cytology | Biomarkers - analysis | Octamer Transcription Factor-3 - pharmacology | Phagocytosis - physiology | Regeneration - physiology | Nerve Tissue Proteins - metabolism | Pluripotent Stem Cells - metabolism | Phenotype | Regeneration - drug effects | Cell Differentiation - drug effects | Octamer Transcription Factor-3 - metabolism | Pluripotent Stem Cells - drug effects | Retinal Rod Photoreceptor Cells - cytology | Cell Polarity - physiology | Brain Tissue Transplantation - methods | Retinal Pigment Epithelium - cytology | Index Medicus
Journal Article
BMC BIOLOGY, ISSN 1741-7007, 11/2017, Volume 15
Background: Peroxisome proliferator activated receptor-alpha (PPARa) is a ubiquitously expressed nuclear receptor. The role of endogenous PPARa in retinal... 
Fatty acid oxidation | ISOMEROHYDROLASE | Retinal energy metabolism | DOWN-REGULATION | Retina | Lipids | ALPHA | RPE65 | DEGENERATION | Mitochondria | Age-related macular degeneration | Neurodegeneration | GLUCOSE-METABOLISM | BIOLOGY | DYSFUNCTION | ENERGY-METABOLISM | AGE
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2017, Volume 114, Issue 41, pp. 10818 - 10820
Journal Article
FRONTIERS IN GENETICS, ISSN 1664-8021, 07/2019, Volume 10, pp. 634 - 634
Currently, there is much interest in intronic sequence-containing long non-coding RNAs and the role of intronic transcription in regulation of cellular... 
retinal dystrophy | ISOMEROHYDROLASE | EVOLUTION | PROTEIN | RNA-seq | MESSENGER-RNA | stable intronic sequence RNA | GENETICS & HEREDITY | long non-coding RNA | visual cycle | MUTATIONS | RETINITIS-PIGMENTOSA
Journal Article
Journal Article