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index medicus (79) 79
animals (61) 61
visual cycle (57) 57
isomerohydrolase (47) 47
biochemistry & molecular biology (44) 44
humans (43) 43
isomerohydrolase activity (41) 41
eye diseases (40) 40
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rpe65 (35) 35
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cis-trans-isomerases - metabolism (26) 26
genetic structures (25) 25
leber congenital amaurosis (25) 25
vitamin-a (25) 25
eye proteins - genetics (24) 24
retina (23) 23
cis-trans-isomerases - genetics (22) 22
vitamin a (22) 22
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retinoids (15) 15
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vision (13) 13
vitamin a - metabolism (13) 13
2 point mutations (12) 12
carrier proteins - metabolism (12) 12
electroretinography (12) 12
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light (12) 12
molecular sequence data (12) 12
multidisciplinary sciences (12) 12
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retinal degeneration (12) 12
retinal pigment epithelium (12) 12
rhodopsin (12) 12
amino acid sequence (11) 11
cis-trans-isomerases - chemistry (11) 11
eye proteins - chemistry (11) 11
kinetics (11) 11
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acyltransferase (10) 10
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isomerase (10) 10
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epithelium (9) 9
gene therapy (9) 9
gene-therapy (9) 9
key residues (9) 9
retinal degeneration - genetics (9) 9
retinoid (9) 9
retinoids - metabolism (9) 9
acyltransferases - metabolism (8) 8
blotting, western (8) 8
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Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2010, Volume 285, Issue 13, pp. 9667 - 9682
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2007, Volume 282, Issue 29, pp. 20915 - 20924
Journal Article
The FEBS journal, ISSN 1742-464X, 6/2009, Volume 276, Issue 11, pp. 3020 - 3030
Generation of 11- cis retinol from all- trans retinyl ester in the retinal pigment epithelium is a critical step in the visual cycle and is essential for... 
retinyl ester | retina | isomerohydrolase | RPE65 | liposome
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2015, Volume 10, Issue 12, pp. e0145305 - e0145305
A2E and related toxic molecules are part of lipofuscin found in the retinal pigment epithelial (RPE) cells in eyes affected by Stargardt's disease, age-related... 
ISOMEROHYDROLASE ACTIVITY | LIPOFUSCIN | PIGMENT EPITHELIUM | MULTIDISCIPLINARY SCIENCES | GLIOMA MODELS | FACTOR-H POLYMORPHISM | MACULAR DEGENERATION | RPE65 MUTATIONS | TERT-BUTYLNITRONE PROTECTS | CONGENITAL AMAUROSIS | VITAMIN-A | Retinal Diseases - prevention & control | Light - adverse effects | Injections, Intraperitoneal | Rats | Male | Retinal Diseases - metabolism | Cyclic N-Oxides - administration & dosage | Papio anubis | Rhodopsin - metabolism | Cyclic N-Oxides - chemistry | Animals | Cattle | Cyclic N-Oxides - pharmacology | Retinal Diseases - etiology | cis-trans-Isomerases - antagonists & inhibitors | Female | Retinal Pigment Epithelium - radiation effects | cis-trans-Isomerases - metabolism | Mice | Retinal Pigment Epithelium - drug effects | Macular degeneration | Prevention | Complications and side effects | Rhodopsin | Care and treatment | Resveratrol | Physiological aspects | Dosage and administration | Research | Dehydrogenases | Enzyme activity | Dark adaptation | Retina | Esters | Damage prevention | Eye | Vitamin A | Enzymatic activity | Phenyl-N-tert-butylnitrone | Light | Eye (anatomy) | Physiology | Degeneration | Inhibition | Age | Electroretinography | Enzymes | Derivatives | Light effects | Microsomes | Electroretinograms | Pathology | Regeneration | Retinal degeneration | Photoreceptors | Diabetes | Mutation | Topical application | Endocrinology | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2008, Volume 105, Issue 39, pp. 15112 - 15117
Journal Article
Journal Article