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Journal Article
Seminars in immunology, ISSN 1044-5323, 2016, Volume 28, Issue 2, pp. 94 - 108
Allergy and Immunology | Immunoreceptors | Syk | ITAM | Neutrophils | SHP | SHIP | ITIM | Life Sciences & Biomedicine | Immunology | Science & Technology | Neutrophil Activation - genetics | Neutrophils - chemistry | Neutrophil Activation - immunology | Disease Susceptibility | Signal Transduction | Humans | Gene Expression Regulation | Neutrophils - immunology | Immunity, Innate | Animals | Biomarkers | Protein Binding | Receptors, Immunologic - genetics | Neutrophils - metabolism | Receptors, Immunologic - metabolism | Tyrosine | Autoimmunity | Immune response | Phosphatases | Autoantibodies | Lipids | Single nucleotide polymorphisms | G proteins | Mitogens | Protein kinases | Membrane proteins | Protein binding | Index Medicus | IgSF, Immunoglobulin superfamily | PI(3,4)P2, phosphatidylinositol (3,4)-bisphosphate | Syk, spleen tyrosine kinase | MPO, myeloperoxidase | SLE, systemic lupus erythematosus | NETs, neutrophil extracellular traps | IVIg, intravenous immunoglobulins | GPCR, G protein-coupled receptor | DAG, diacyl-glycerol | PH domain, pleckstrin homology domain | fMLP, N-Formylmethionine-leucyl-phenylalanine | GPI, glycophosphatidylinositol | PE, phosphatidylethanolamine | ADCC, antibody-dependent cellular cytotoxicity | SHIP, SH2-domain containing inositol phosphatase | DAP12, DNAX activation protein of 12 kDa | IP3, inositol triphosphate | NADPH, nicotinamide adenine dinucleotide phosphate | SH2, Src homology 2 | Grb2, growth factor receptor-bound protein 2 | MAPK, mitogen-activated protein kinase | ITAM, immunoreceptor tyrosine-based activating motif | MRP8, myeloid-related protein 8 | PMN, polymorphonuclear leukocytes | MLCK, myosin light-chain kinase | PLC, phospholipase C | Btk, Bruton's tyrosine kinase | RA, rheumatoid arthritis | SNP, single-nucleotide polymorphism | ITIM, immunoreceptor tyrosine-based inhibitory motif | PIP2, phosphatidylinositol (4,5)-bisphosphate | GBS, group B Streptococci | SLP-76, SH2 domain containing leukocyte protein of 76 kDa | SHP, SH2-domain containing phosphatase | PTPN6, tyrosine-protein phosphatase non-receptor type 6 | ANCAs, anti-neutrophil autoantibodies | ROS, reactive oxygen species | PI3K, phosphatidylinositol-4,5-bisphosphate 3-kinase | PKC, protein kinase C | SOCS, suppressor of cytokine signaling proteins | ORF, open reading frame | PIP3, phosphatidylinositol (3,4,5)-trisphosphate | IRAK, interleukin-1 receptor-associated kinase | PS, phosphatidylserine | ERK, extracellular signal-regulated kinase | GEF, guanine nucleotide exchange factor
Journal Article