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mAbs, ISSN 1942-0862, 01/2015, Volume 7, Issue 3, pp. 605 - 619
Interleukin-1 (IL-1) cytokines such as IL-1 alpha, IL-1 beta, and IL-1Ra contribute to immune regulation and inflammatory processes by exerting a wide range of... 
ABT-981 | DVD-Ig | IL-1 antagonist | IL-1β | IL-1α | Osteoarthritis | MEDICINE, RESEARCH & EXPERIMENTAL | COLLAGENASE PRODUCTION | RHEUMATOID SYNOVIAL-CELLS | RABBIT KNEE-JOINTS | INTRAARTICULAR INJECTION | INTERLEUKIN-1 RECEPTOR ANTAGONIST | HUMAN CHONDROCYTES | IN-VIVO | NECROSIS-FACTOR-ALPHA | ADA, Anti-drug antibodies; CDR, complementarity-determining region; CEC, cation exchange chromatography; Cyno, cynomolgus monkey; DVD-Ig, dual variable domain immunoglobulin; ED50, efficacious dose at 50% response; ED80, efficacious dose at 80% response; ELISA, enzyme-linked immunosorbent assay; IL-1, interleukin-1; IgG1, immunoglobulin G1; IV, intravenous; OA, osteoarthritis; PAS, protein A sepharose; SC, subcutaneous; SEC, size exclusion chromatography; SPR, surface plasmon resonance; V-H, antibody heavy chain variable domain; V-L, antibody light chain variable domain | FC-GAMMA-RIIA | EXPERIMENTAL OSTEOARTHRITIS | Antibody Specificity | Interleukin-1alpha - immunology | Interleukin-1alpha - chemistry | Humans | Immunoglobulin G - chemistry | Immunoglobulin Variable Region - chemistry | Interleukin-1alpha - antagonists & inhibitors | Interleukin-1beta - immunology | Antibodies, Neutralizing - pharmacology | Antibody Affinity | Immunoglobulin Variable Region - immunology | Antibodies, Neutralizing - immunology | Animals | Immunoglobulin G - immunology | Antibodies, Neutralizing - chemistry | Immunoglobulin Variable Region - pharmacology | Interleukin-1beta - chemistry | Immunoglobulin G - pharmacology | Female | Mice | Interleukin-1beta - antagonists & inhibitors
Journal Article
Inorganic Chemistry, ISSN 0020-1669, 04/2011, Volume 50, Issue 8, pp. 3717 - 3728
Journal Article
Psychosomatic Medicine, ISSN 0033-3174, 10/2016, Volume 78, Issue 8, pp. 931 - 939
Objective Several studies have reported an association between nonceliac gluten sensitivity and schizophrenia. Immune and kynurenine (KYN) pathways have also... 
kynurenine | schizophrenia | tryptophan | antigliadine immunoglobulin antibodies | nonceliac gluten sensitivity | IMMUNE-RESPONSE | CSF = cerebrospinal fluid | IgG = immunoglobulin G | INDOLEAMINE 2,3-DIOXYGENASE | KMO= kynurenine 3-monooxygenase | 3-dioxygenase | PSYCHOLOGY | NMDA = N-methyl-d-aspartic acid | INDIVIDUALS | PSYCHOLOGY, MULTIDISCIPLINARY | CELIAC GLUTEN SENSITIVITY | T-CELL RESPONSES | NEUROINFLAMMATION | BMI = body mass index | BRAIN | Fourth Edition | DSM-IV = Diagnostic and Statistical Manual of Mental Disorders | IDO = indoleamine 2 | ACID | PSYCHIATRY | PANSS = Positive and Negative Syndrome Scale | HPLC = high-performance liquid chromatography | TDO = tryptophan 2 | KYNA = kynurenic acid | TRP = tryptophan | KYN = kynurenine | PREFRONTAL CORTEX | DISEASE | ELISA = enzyme-linked immunosorbent assay | QUIN= quinolinic acid | Kynurenine - blood | Schizophrenia - immunology | Tryptophan - blood | Gliadin - immunology | Immunoglobulin G - blood | Schizophrenia - blood | Humans | Middle Aged | Adult | Female | Male | Immunoglobulins | Pathophysiological aspects | Mental disorders | Immunoglobulin G | Antibodies | Individualized | Schizophrenia | Tryptophan | Amino acids | Immunoglobulin | Inflammation | Regression analysis | Metabolism | Patients | Sensitivity | Metabolites | Psychoses | Gliadin | Serum | Deviation | Gluten
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 08/2018, Volume 115, Issue 34, pp. 8615 - 8620
Journal Article
Immunity, ISSN 1074-7613, 2006, Volume 25, Issue 1, pp. 31 - 41
DNA polymerases mu (pol μ), lambda (pol λ), and terminal deoxynucleotidyltransferase (TdT) are enzymes of the pol X family that share homology in sequence and... 
MOLIMMUNO | DNA | STRAND BREAK REPAIR | HUMAN-CELLS | N-REGIONS | X FAMILY | DEFICIENT | POL-MU | DEPENDENT PROTEIN-KINASE | MICE | IMMUNOLOGY | LIGASE-IV | SPLICE VARIANTS | DNA-Directed DNA Polymerase - deficiency | DNA-Directed DNA Polymerase - genetics | DNA Polymerase beta - deficiency | Cellular Senescence - immunology | Immunoglobulin J-Chains - genetics | Isoenzymes - metabolism | Recombination, Genetic | Base Sequence | RNA Splicing - genetics | Fibroblasts | Cell Differentiation | DNA Polymerase beta - metabolism | DNA Polymerase beta - genetics | Gene Rearrangement, B-Lymphocyte - genetics | B-Lymphocytes - cytology | Cells, Cultured | DNA Nucleotidylexotransferase - classification | Gene Expression Regulation | DNA Nucleotidylexotransferase - metabolism | Mice, Knockout | Sequence Alignment | Animals | B-Lymphocytes - immunology | Immunoglobulin Variable Region - genetics | Mice | DNA-Directed DNA Polymerase - metabolism | Gene Rearrangement - genetics | Competition | Enzymes | Genes | Light | Genomes | DNA repair | Deoxyribonucleic acid--DNA | Isoenzymes | DNA Polymerase beta | B-Lymphocytes | Cell Aging | Immunoglobulin J-Chains | Life Sciences | RNA Splicing | Immunology | Gene Rearrangement | DNA Nucleotidylexotransferase | Gene Rearrangement, B-Lymphocyte | Immunoglobulin Variable Region | DNA-Directed DNA Polymerase
Journal Article
Leukemia, ISSN 0887-6924, 2017, Volume 31, Issue 12, pp. 2552 - 2559
Interactions between killer-immunoglobulin-like receptors (KIRs) and their HLA class I ligands are instrumental in natural killer (NK) cell regulation and... 
MHC CLASS-I | SURVIVAL | DIAGNOSIS | RELAPSE | NK CELLS | ONCOLOGY | KIR | HISTAMINE DIHYDROCHLORIDE | INHIBITORY RECEPTORS | HEMATOLOGY | EXPRESSION | SELF-TOLERANCE | Prognosis | Receptors, KIR - genetics | Humans | HLA Antigens - immunology | Genotype | Treatment Outcome | HLA Antigens - genetics | Clinical Trials, Phase IV as Topic | Leukemia, Myeloid, Acute - mortality | Lymphocyte Activation - immunology | Leukemia, Myeloid, Acute - diagnosis | Multicenter Studies as Topic | Lymphocyte Activation - drug effects | Immunotherapy | Receptors, KIR - metabolism | Survival Analysis | Interleukin-2 - pharmacology | Killer Cells, Natural - immunology | Ligands | Killer Cells, Natural - drug effects | Killer Cells, Natural - metabolism | Leukemia, Myeloid, Acute - therapy | Leukemia, Myeloid, Acute - genetics | Immunoglobulins | Killer cells | Histocompatibility antigens | HLA histocompatibility antigens | Research | Health aspects | Haplotypes | Toxicity | Myeloid leukemia | Leukemia | Effector cells | Cytotoxicity | Immunoglobulin-like receptors | T cell receptors | Patients | White blood cells | Genotype & phenotype | Histamine | Receptors | Interleukin 2 | Killer cell immunoglobulin-like receptors | Histocompatibility antigen HLA | Natural killer cells | Acute myeloid leukemia | Genotypes | Original | unlicensed nk cells | Hematology | inhibitory receptors | molecules | Oncology | cytomegalovirus-infection | self-tolerance | international expert panel | mhc class-i | Hematologi | class-i | kir | complex | Cancer and Oncology | histamine dihydrochloride | Cancer och onkologi
Journal Article
Journal Article
Hepatology, ISSN 0270-9139, 02/2018, Volume 67, Issue 2, pp. 721 - 735
Complement plays a role in both hepatic ischemia reperfusion (IR) injury (IRI) and liver regeneration, but it is not clear how complement is activated in... 
C-REACTIVE PROTEIN | SKELETAL-MUSCLE | MURINE MODEL | CELLS | COMPLEMENT | RECOGNITION | LIVER-REGENERATION | IDENTIFICATION | GASTROENTEROLOGY & HEPATOLOGY | IGM | ISCHEMIA/REPERFUSION | Immunoglobulin M | Immunoglobulins | Animal models | Syngeneic grafts | Phospholipids | Transplantation | Inflammation | Reperfusion | Ischemia | RAG1 protein | Rodents | Annexin IV | Monoclonal antibodies | Liver transplantation
Journal Article
Expert Opinion on Drug Metabolism & Toxicology, ISSN 1742-5255, 11/2016, Volume 12, Issue 11, pp. 1343 - 1358
Journal Article