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Toxicological Sciences, ISSN 1096-6080, 05/2018, Volume 163, Issue 1, pp. 152 - 169
Abstract Prioritizing the risk posed by thousands of chemicals potentially present in the environment requires exposure, toxicity, and toxicokinetic (TK) data,... 
Toxicokinetics | Environmental chemicals | IVIVE | toxicokinetics | environmental chemicals | METABOLIC-CLEARANCE | HEPATIC-CLEARANCE | PREDICTION | CRYOPRESERVED HUMAN HEPATOCYTES | PHARMACOKINETIC PARAMETERS | TOXICITY DATA | TOXICOLOGY | RISK-ASSESSMENT | DOSIMETRY | EXPOSURE | Ivive and Toxicokinetics
Journal Article
Journal Article
Chemosphere, ISSN 0045-6535, 01/2020, Volume 238, p. 124645
Bromophenols (BPs) are important organic compounds which have become dominant pollutants during these years. Our present study investigated the potential... 
Human UDP-Glucuronosyltransferases (UGTs) | Bromophenols (BPs) | Bromine substituent | Inhibition | In vitro-in vivo extrapolation (IVIVE)
Journal Article
Journal Article
Journal Article
Environmental Pollution, ISSN 0269-7491, 11/2019, Volume 254, Issue Pt B, p. 113093
Per- and polyfluoroalkyl substances (PFASs) are a large group of chemicals and can be detected in environmental and human samples all over the world. Toxicity... 
Inhibition type | Per- and polyfluoroalkyl substances (PFASs) | UDP-Glucuronosyltransferases (UGTs) | In vitro-in vivo extrapolation (IVIVE) | Inhibition kinetic parameters (Ki) | Half inhibition concentration (IC50)
Journal Article
Journal Article
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 2014, Volume 42, Issue 9, pp. 1478 - 1484
Prediction accuracy of pharmacokinetic parameters is often assessed using prediction fold error, i.e., being within 2-, 3-, or n-fold of observed values.... 
PHASE | METABOLISM | MODELS | WARFARIN | INTERINDIVIDUAL VARIABILITY | IVIVE | PHARMACOLOGY & PHARMACY | DRUG CLEARANCE | CYP2C19 | PREDICTION | Predictive Value of Tests | Pharmaceutical Preparations - metabolism | Models, Biological | Humans | In Vitro Techniques - methods | Statistics as Topic | Kinetics | Metabolic Clearance Rate - physiology | Index Medicus
Journal Article