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Journal of Thrombosis and Haemostasis, ISSN 1538-7933, 02/2010, Volume 8, Issue 2, pp. 324 - 330
Background: The adhesion receptor glycoprotein (GP)Ib–IX–V, which binds von Willebrand factor (VWF) and other ligands, initiates platelet activation and... 
14‐3‐3ζ | phosphoinositide‐3‐kinase | platelets | GPIb–IX–V | 14-3-3ζ | Phosphoinositide-3-kinase | GPIb-IX-V | Platelets | CYTOPLASMIC DOMAIN | ACTIVATION | 3-KINASE | IDENTIFICATION | VON-WILLEBRAND-FACTOR | SIGNALING PROTEIN | ADHESION RECEPTOR | LEUCINE-RICH REPEATS | SEQUENCE | 14-3-3 zeta | phosphoinositide-3-kinase | 14-3-3-ZETA BINDING | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 02/2014, Volume 111, Issue 2, pp. 279 - 289
Platelet adhesion and aggregation at the sites of vascular injury are key events for thrombosis and haemostasis. It has been well demonstrated that interaction... 
Antithrombotic agent | snake venoms | platelet inhibitor | glycoprotein Ib-IX-V complex | Platelets and Blood Cells | Glycoprotein ib-ix-v complex | Platelet inhibitor | Snake venoms | C-TYPE LECTIN | AGKISTRODON-ACUTUS | ARTERIAL THROMBOSIS | HIGH-SHEAR | VON-WILLEBRAND-FACTOR | MOUSE MODEL | FACTOR-IX | ALVEOLAR HEMORRHAGE | GLYCOPROTEIN-IB-ALPHA | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | AGGREGATION | Crotalid Venoms - pharmacology | Male | von Willebrand Factor - genetics | Platelet Aggregation Inhibitors - toxicity | Platelet Glycoprotein GPIb-IX Complex - metabolism | Vascular System Injuries - complications | Time Factors | Chlorides | Platelet Aggregation Inhibitors - pharmacology | Female | Platelet Aggregation - drug effects | Thrombosis - blood | Thrombosis - prevention & control | Blood Platelets - drug effects | Binding Sites | Crotalid Venoms - toxicity | Disease Models, Animal | von Willebrand Factor - metabolism | Lectins, C-Type | Mice, Inbred C57BL | Mice, Knockout | Platelet Adhesiveness - drug effects | Ferric Compounds | Fibrinolytic Agents - pharmacology | Animals | Blood Platelets - metabolism | Thrombosis - etiology | Platelet Glycoprotein GPIb-IX Complex - antagonists & inhibitors | Protein Binding | Thrombosis - genetics | Mice | Fibrinolytic Agents - toxicity | Hemorrhage - chemically induced
Journal Article
Circulation, ISSN 0009-7322, 2007, Volume 115, Issue 17, pp. 2323 - 2330
Background - Ischemic stroke is a frequent and serious disease with limited treatment options. Platelets can adhere to hypoxic cerebral endothelial cells by... 
Cerebrovascular disorders | Stroke | Magnetic resonance imaging | Glycoproteins | Drug therapy | Platelets | Intracerebral hemorrhage | MIDDLE CEREBRAL-ARTERY | magnetic resonance imaging | CARDIAC & CARDIOVASCULAR SYSTEMS | drug therapy | COLLAGEN | THROMBUS FORMATION | RECEPTOR | glycoproteins | MONOCLONAL-ANTIBODY | stroke | VON-WILLEBRAND-FACTOR | platelets | intracerebral hemorrhage | PLASMINOGEN-ACTIVATOR | ACUTE ISCHEMIC-STROKE | IN-VIVO | PERIPHERAL VASCULAR DISEASE | IX-V | cerebrovascular disorders | Acute Disease | Platelet Glycoprotein GPIIb-IIIa Complex - immunology | Platelet Membrane Glycoproteins - immunology | Ischemic Attack, Transient - therapy | Signal Transduction | Antibodies, Monoclonal - pharmacology | Mice, Inbred C57BL | Risk Factors | Cerebral Hemorrhage - mortality | Male | Blood Platelets - physiology | Infarction, Middle Cerebral Artery - pathology | Infarction, Middle Cerebral Artery - therapy | Immunoglobulin Fab Fragments - pharmacology | Infarction, Middle Cerebral Artery - blood | Platelet Glycoprotein GPIIb-IIIa Complex - antagonists & inhibitors | Platelet Membrane Glycoproteins - antagonists & inhibitors | Magnetic Resonance Imaging | Animals | Platelet Glycoprotein GPIb-IX Complex - antagonists & inhibitors | Mice | Ischemic Attack, Transient - blood | Platelet Glycoprotein GPIb-IX Complex - immunology | Ischemic Attack, Transient - pathology | Stroke (Disease) | Physiological aspects | Development and progression | Usage | Animal models in research
Journal Article
Journal Article
Annals of Hematology, ISSN 0939-5555, 5/2009, Volume 88, Issue 5, pp. 465 - 472
Bernard–Soulier syndrome (BSS) is a rare autosomal recessive genetic disorder characterized by thrombocytopenia, circulating giant platelets, and prolonged... 
Medicine & Public Health | Hematology | Bernard–Soulier syndrome | Giant platelets | GPIb–IX–V complex | Oncology | GPIbβ mutation | GPIb-IX-V complex | Bernard-Soulier syndrome | PLATELET GLYCOPROTEIN-IB | ADHESION | DOMAIN | TRANSMEMBRANE | ALPHA | HEMATOLOGY | VON-WILLEBRAND-FACTOR | GPIb beta mutation
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 12/2010, Volume 30, Issue 12, pp. 2341 - 2349
Upon vascular injury, platelets are activated by adhesion to adhesive proteins, such as von Willebrand factor and collagen, or by soluble platelet agonists,... 
G proteins | receptors | adhesion molecules | signal transduction | platelets | INTEGRIN ALPHA(IIB)BETA | THROMBUS FORMATION | TYROSINE KINASE | DEPENDENT PROTEIN-KINASE | IX-V COMPLEX | VON-WILLEBRAND-FACTOR |