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ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, ISSN 0066-4804, 05/2017, Volume 61, Issue 5
para-Aminosalicylic acid (PAS) is a second-line antituberculosis drug that has been used to treat multidrug-resistant and extensively drug-resistant... 
MYCOBACTERIUM-TUBERCULOSIS | METHOTREXATE | ELIMINATION | MICROBIOLOGY | GENETIC-VARIANTS | antituberculosis drug | ORGANIC CATION TRANSPORTERS | 22 ANTITUBERCULOSIS DRUGS | drug-drug interactions | THERAPY | PHARMACOKINETICS | membrane transporter | RESISTANCE | PHARMACOLOGY & PHARMACY | ANION TRANSPORTER | Octamer Transcription Factor-1 - antagonists & inhibitors | Organic Anion Transport Protein 1 - metabolism | Proton Pump Inhibitors - pharmacology | Organic Anion Transporters, Sodium-Independent - antagonists & inhibitors | Humans | Naproxen - pharmacology | Organic Cation Transporter 2 - antagonists & inhibitors | Organic Cation Transporter 2 - metabolism | Aminosalicylic Acid - metabolism | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Aminosalicylic Acid - pharmacokinetics | Organic Anion Transporters, Sodium-Independent - metabolism | HEK293 Cells | ATP-Binding Cassette Transporters - metabolism | Biological Transport - drug effects | Cell Line | Organic Anion Transport Protein 1 - antagonists & inhibitors | Ibuprofen - pharmacology | Antitubercular Agents - pharmacology | Probenecid - pharmacology | Quinidine - pharmacology | Verapamil - pharmacology | Antitubercular Agents - pharmacokinetics | Solute Carrier Organic Anion Transporter Family Member 1b1 - antagonists & inhibitors | Solute Carrier Organic Anion Transporter Family Member 1b1 - metabolism | Drug Interactions - physiology | Cimetidine - pharmacology | Aminosalicylic Acid - pharmacology | Biological Transport - physiology | Rifampin - pharmacology | Antitubercular Agents - metabolism | Octamer Transcription Factor-1 - metabolism
Journal Article
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 12/2001, Volume 345, Issue 25, pp. 1809 - 1817
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 02/2012, Volume 340, Issue 2, pp. 422 - 432
Phospho-nonsteroidal anti-inflammatory drugs (phospho-NSAIDs) are novel NSAID derivatives with improved anticancer activity and reduced side effects in... 
Organophosphates - metabolism | Indomethacin - analogs & derivatives | Naproxen - analogs & derivatives | Humans | Naproxen - pharmacology | Phenylglyoxal - analogs & derivatives | Indomethacin - metabolism | Valproic Acid - analogs & derivatives | Anti-Inflammatory Agents, Non-Steroidal - blood | Naproxen - metabolism | Organophosphorus Compounds - metabolism | Valproic Acid - pharmacology | Ibuprofen - analogs & derivatives | Aspirin - metabolism | Nitrophenols - therapeutic use | Organophosphorus Compounds - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - metabolism | Aspirin - pharmacology | Carboxylesterase - antagonists & inhibitors | Valproic Acid - metabolism | Cell Survival - drug effects | Organophosphates - blood | Enzyme Inhibitors - pharmacology | Organophosphorus Compounds - therapeutic use | Stomach Neoplasms - drug therapy | Ibuprofen - metabolism | Indomethacin - pharmacology | Aspirin - analogs & derivatives | Mice, Nude | Carboxylesterase - genetics | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Kinetics | Organophosphates - therapeutic use | Stomach Neoplasms - pathology | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Sulindac - metabolism | Transfection | Nitrophenols - pharmacology | HEK293 Cells | Inhibitory Concentration 50 | Female | Sulindac - blood | Carboxylic Ester Hydrolases - genetics | Carboxylic Ester Hydrolases - antagonists & inhibitors | Ibuprofen - pharmacology | Phenylglyoxal - pharmacology | Sulindac - therapeutic use | Carboxylesterase - metabolism | Hydrolysis | Organophosphates - pharmacology | Xenograft Model Antitumor Assays | Sulindac - analogs & derivatives | Drug Therapy, Combination - methods | Animals | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Drug Interactions - physiology | Organophosphorus Compounds - blood | Sulindac - pharmacology | Carboxylic Ester Hydrolases - metabolism
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2005, Volume 280, Issue 7, pp. 5892 - 5901
Alzheimer's disease (AD) involves amyloid beta (Abeta) accumulation, oxidative damage, and inflammation, and risk is reduced with increased antioxidant and... 
PROTEIN | CLINICAL-TRIAL | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | ALZHEIMERS-DISEASE | CONGO RED | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE MODEL | CHEMOPREVENTIVE AGENT | NF-KAPPA-B | CACHE COUNTY | TRANSGENIC MICE | Protein Denaturation - drug effects | Peptide Fragments - toxicity | Benzoates - chemistry | Curcumin - chemistry | Humans | Naproxen - pharmacology | Plaque, Amyloid - chemistry | Curcumin - metabolism | Pyridazines - pharmacology | Alzheimer Disease - pathology | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Brain - metabolism | Biphenyl Compounds - pharmacology | Protein Binding - drug effects | Amyloid beta-Peptides - metabolism | Thiazoles | Blood-Brain Barrier - physiology | Anti-Inflammatory Agents, Non-Steroidal - metabolism | Biphenyl Compounds - chemistry | Peptide Fragments - metabolism | Ibuprofen - pharmacology | Plaque, Amyloid - pathology | Amyloid beta-Peptides - toxicity | Curcumin - pharmacology | Solubility | Mice, Transgenic | Protein Structure, Quaternary - drug effects | Blood-Brain Barrier - drug effects | Plaque, Amyloid - genetics | Pyridazines - chemistry | Brain - drug effects | Amyloid beta-Peptides - antagonists & inhibitors | Peptide Fragments - chemistry | Animals | Congo Red | Peptide Fragments - antagonists & inhibitors | Alzheimer Disease - metabolism | Benzoates - pharmacology | Brain - pathology | Cell Line, Tumor | Diamines - chemistry | Diamines - pharmacology | Plaque, Amyloid - metabolism | Mice | Amyloid beta-Peptides - chemistry | Alzheimer Disease - genetics
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2015, Volume 10, Issue 9, p. e0139212
Background Increased endocannabinoid tonus by dual-action fatty acid amide hydrolase (FAAH) and substrate selective cyclooxygenase (COX-2) inhibitors is a... 
IBUPROFEN | ENZYME | COX-2 | OXYGENATION | ENDOCANNABINOIDS | MULTIDISCIPLINARY SCIENCES | ANANDAMIDE | INDOMETHACIN | FLURBIPROFEN | LINEAR-MODELS | ANTIINFLAMMATORY DRUGS | Endocannabinoids - metabolism | Stereoisomerism | Humans | Brain - enzymology | Male | Arachidonic Acids - metabolism | Isoenzymes - metabolism | Benzamides - pharmacology | Carbamates - pharmacology | Amides - pharmacology | Amidohydrolases - metabolism | Amidohydrolases - antagonists & inhibitors | Polyunsaturated Alkamides - metabolism | Cyclooxygenase Inhibitors - pharmacology | Hydrolysis | Animals | Arachidonic Acid - pharmacology | Cyclooxygenase 2 - metabolism | Lipid Metabolism - drug effects | Lipopolysaccharides - pharmacology | Amides - chemistry | Ionomycin - pharmacology | RAW 264.7 Cells | Mice | Cyclooxygenase 1 - metabolism | Flurbiprofen - pharmacology | Interferon-gamma - pharmacology | Prostaglandins - metabolism | Brain | COX-2 inhibitors | Neurosciences | Lipids | Enantiomers | Arachidonic acid | Macrophages | Prostaglandin endoperoxide synthase | Pain | 2-Arachidonylglycerol | Rodents | Nonsteroidal anti-inflammatory drugs | Flurbiprofen | Functional foods & nutraceuticals | Fatty-acid amide hydrolase | Enzymes | Hydrolase | Substrate inhibition | Pharmacology | Prostaglandin D2 | Fatty acids | Substrates | Anandamide | Environmental science | Inhibitors | Cyclooxygenase-1 | Interferon | Cyclooxygenase-2 | Oxygenation | Pharmaceuticals | Basic Medicine | Farmakologi och toxikologi | Medical and Health Sciences | Pharmacology and Toxicology | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 07/2012, Volume 199, Issue 1, pp. 18 - 28
Journal Article