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by Xie, Z and Yu, HJ and Sun, XW and Tang, P and Jie, ZW and Chen, S and Wang, JY and Qin, A and Fan, SW
JOURNAL OF BONE AND MINERAL RESEARCH, ISSN 0884-0431, 04/2018, Volume 33, Issue 4, pp. 667 - 678
Osteoporosis develops because of impaired bone formation and/or excessive bone resorption. Although the pharmacological treatment of osteoporosis has been... 
THERAPEUTICS | CELLS | OSTEOBLAST DIFFERENTIATION | OVARIECTOMY-INDUCED OSTEOPOROSIS | IFRD1 | OSTEOGENESIS | MECHANISMS | OSTEOPOROSIS | RUNX2 | OSTEOCLASTOGENESIS | ORIDONIN | SIGNALING PATHWAY | BONE-FORMATION | IN-VIVO | ENDOCRINOLOGY & METABOLISM | DEGRADATION | NF-KAPPA-B
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 04/2018, Volume 33, Issue 4, pp. 667 - 678
Osteoporosis develops because of impaired bone formation and/or excessive bone resorption. Although the pharmacological treatment of osteoporosis has been... 
OSTEOCLASTOGENESIS | THERAPEUTICS | NF-Κβ | ORIDONIN | IFRD1 | OSTEOGENESIS | OSTEOPOROSIS | Smad5 protein | Phosphorylation | Transcription | Ovariectomy | Osteoblasts | Nuclear transport | Bone resorption | Osteoclastogenesis | Osteoporosis | Bone growth | Osteoblastogenesis | Mineralization | Proteasomes | Osteoclasts | Interferon | TRANCE protein | Bone loss | Osteogenesis
Journal Article
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ISSN 0006-291X, 01/2017, Volume 482, Issue 2, pp. 329 - 334
We previously demonstrated that the transcriptional coactivator/repressor interferon-related developmental regulator 1 (Ifrd1) was expressed in osteoblasts and... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | STEM-CELL NICHE | ADIPOGENESIS | Osteoblasts | SIGNAL-TRANSDUCTION | BMP2 | Smads | BIOPHYSICS | BONE-FORMATION | PATHWAY | Ifrd1 | DIFFERENTIATION | RECEPTORS | SKELETAL DEVELOPMENT
Journal Article
Rhinology, ISSN 0300-0729, 2015, Volume 53, Issue 4, pp. 359 - 364
Background: Nasal polyposis (NP) is an inflammatory disease of the upper nasal airways frequently present in CF patients. Interferon-Related Developmental... 
Nasal polyposis | Cystic fibrosis | Modifier genes | IFRD1 | CELLS | GENOTYPE | PHENOTYPE | NEUTROPHILS | modifier genes | nasal polyposis | cystic fibrosis | OTORHINOLARYNGOLOGY | MUTATION | DISEASE | UPDATE | EXPRESSION
Journal Article
Journal Article
Journal Article
The FEBS Journal, ISSN 1742-464X, 03/2017, Volume 284, Issue 5, pp. 784 - 795
Sympathetic tone activates the function of classical brown adipocytes, which constitutively exist in the brown adipose tissue (BAT), and inducible brown... 
| Sp1 | PGC | brown adipocyte | Ifrd1 | sympathetic tone | PGC-1α | COACTIVATOR | ACTIVATION | PGC-1 alpha | BEIGE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MECHANISMS | ADIPOGENESIS | IDENTIFICATION | THERMOGENESIS | GROWTH-DIFFERENTIATION FACTOR-5 | TIS7 | ADIPOSE-TISSUE | Adrenergic Agonists - administration & dosage | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha - genetics | Thermogenesis - genetics | Cold Temperature | Adipocytes, Brown - metabolism | Membrane Proteins - genetics | Immediate-Early Proteins - biosynthesis | Adipose Tissue, White - metabolism | Repressor Proteins - genetics | Multiprotein Complexes - genetics | Sp1 Transcription Factor - metabolism | Gene Expression Regulation - drug effects | Immediate-Early Proteins - metabolism | Multiprotein Complexes - metabolism | Membrane Proteins - biosynthesis | Animals | Immediate-Early Proteins - genetics | Sp1 Transcription Factor - genetics | Dioxoles - administration & dosage | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha - metabolism | Adipose Tissue, Brown - metabolism | Membrane Proteins - metabolism | Mice | Repressor Proteins - metabolism | Histone deacetylase | Adipose tissue | Complex formation | Adrenal glands | Stimulation | Adipocytes | Gene expression | Sympathetic nervous system | Sp1 protein | Proteins | Mitochondria | Sympathomimetics | Trichostatin A | Interferon | Adipose tissue (brown)
Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 01/2013, Volume 48, Issue 1, pp. 71 - 77
Journal Article
This study focuses on a gene, IFRD1. We believe that IFRD1 is a stress responsive gene that is tightly regulated by eIF2 alpha and may play a key role in cell... 
GCN2 | integrated stress response. eIF2 alpha | IFRD1
Dissertation
Cystic fibrosis is the most common, lethal autosomal recessive disorder in the United States. Lung disease is the major cause of morbidity and mortality in CF.... 
Modifier gene | Cystic Fibrosis | neutrophil | IFRD1 | HDAC
Dissertation
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