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Nature immunology, ISSN 1529-2916, 2012, Volume 13, Issue 10, pp. 972 - 980
Journal Article
Journal of Immunology, ISSN 0022-1767, 10/2017, Volume 199, Issue 7, pp. 2377 - 2387
Journal Article
Nature (London), ISSN 1476-4687, 2017, Volume 542, Issue 7642, pp. 479 - 483
B-lymphoid transcription factors, such as PAX5 and IKZF1, are critical for early B-cell development(1,2... 
ENERGY STRESS | ACTIVATION | GENE | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | ACUTE LYMPHOBLASTIC-LEUKEMIA | HEMATOPOIETIC STEM-CELLS | REGULATORY NETWORK | DIFFERENTIATION | MINIMAL RESIDUAL DISEASE | EXPRESSION | Glucocorticoids - therapeutic use | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - pathology | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Receptor, Cannabinoid, CB2 - agonists | Humans | Gene Expression Regulation, Neoplastic | Receptors, Glucocorticoid - metabolism | PAX5 Transcription Factor - deficiency | Carrier Proteins - agonists | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Chromatin Immunoprecipitation | Adenosine Triphosphate - metabolism | Cell Death | Pyruvic Acid - metabolism | Female | Ikaros Transcription Factor - metabolism | Energy Metabolism - genetics | B-Lymphocytes - metabolism | PAX5 Transcription Factor - metabolism | Protein-Serine-Threonine Kinases - metabolism | Disease Models, Animal | AMP-Activated Protein Kinases - antagonists & inhibitors | Carcinogenesis - genetics | PAX5 Transcription Factor - genetics | Mice, Transgenic | Citric Acid Cycle | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Transcription Factors - metabolism | B-Lymphocytes - drug effects | Receptor, Cannabinoid, CB2 - metabolism | Animals | Carrier Proteins - metabolism | Sequence Analysis, RNA | Glucocorticoids - pharmacology | Glucose - metabolism | Mice | Physiological aspects | Transcription factors | B cells | Proteins | Metabolites | Rodents | Cloning | Leukemia | Glucose | Kinases | Metabolism | Gene expression | Apoptosis
Journal Article
Journal Article
Nature immunology, ISSN 1529-2908, 2017, Volume 18, Issue 6, pp. 694 - 704
The transcription factor STAT5 has a critical role in B cell acute lymphoblastic leukemia (B... 
MAINTENANCE | ACTIVATION | PROTEIN | DISRUPTION | SUPER-ENHANCERS | IKAROS | ACUTE LYMPHOBLASTIC-LEUKEMIA | RECEPTOR | IMMUNOLOGY | NF-KAPPA-B | EXPRESSION | Prognosis | Humans | Gene Expression Regulation, Neoplastic | Protein Kinase C beta - genetics | B-Lymphocytes | Precursor Cell Lymphoblastic Leukemia-Lymphoma - mortality | NF-kappa B p50 Subunit - genetics | Ikaros Transcription Factor - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - metabolism | STAT5 Transcription Factor - metabolism | Protein-Tyrosine Kinases - genetics | Flow Cytometry | Chromatin Immunoprecipitation | Trans-Activators - genetics | Pre-B Cell Receptors - genetics | Real-Time Polymerase Chain Reaction | Signal Transduction | PAX5 Transcription Factor - genetics | Interferon Regulatory Factors - genetics | Proto-Oncogene Proteins - genetics | Survival Rate | Multiplex Polymerase Chain Reaction | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Animals | Agammaglobulinaemia Tyrosine Kinase | Adaptor Proteins, Signal Transducing - genetics | Mice | Care and treatment | Immune response | Development and progression | STAT5 | Genetic aspects | Acute lymphocytic leukemia | Health aspects | Protein kinase C | Transcription factors | Ikaros protein | Acute lymphatic leukemia | Cell survival | Leukemia | Gene regulation | T cell receptors | Stat5 protein | Lymphatic leukemia | B-cell receptor | Gene expression | Pax5 protein | Bruton's tyrosine kinase | Defects | Enhancers | PU.1 protein | BLNK protein | Lymphocytes B | Interferon regulatory factor 4
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 04/2012, Volume 90, Issue 4, pp. 648 - 660
Journal Article
Journal Article
The EMBO Journal, ISSN 0261-4189, 11/2014, Volume 33, Issue 22, pp. 2721 - 2734
Journal Article
Nature immunology, ISSN 1529-2916, 2015, Volume 16, Issue 7, pp. 775 - 784
...) and controlled expression of the gene encoding the transcription factor c-Myc (Myc) to modulate the expression of genes encoding products that regulate ribosome biogenesis... 
TRANSCRIPTION FACTORS | GENOMIC INTERACTIONS | HEMATOPOIETIC PROGENITOR CELLS | LEUKEMIA MAINTENANCE | IKAROS | DNA-BINDING PROTEINS | GENE-EXPRESSION | C-MYC | IMMUNOLOGY | REGULATORY ELEMENTS | LOCUS | Cell Proliferation | Precursor Cells, B-Lymphoid - metabolism | Chromatin Assembly and Disassembly - genetics | Precursor Cells, B-Lymphoid - immunology | DNA Helicases - immunology | Cell Differentiation - genetics | Flow Cytometry | Nuclear Proteins - genetics | Transcription Factors - immunology | DNA Helicases - genetics | Immunoglobulin Heavy Chains - immunology | B-Lymphocytes - metabolism | Cell Lineage - genetics | RNA Interference - immunology | Gene Expression Regulation - genetics | Gene Expression Regulation - immunology | Cells, Cultured | Proto-Oncogene Proteins c-myc - immunology | In Situ Hybridization, Fluorescence | Mice, Transgenic | Nuclear Proteins - metabolism | Transcription Factors - genetics | Enhancer Elements, Genetic - immunology | Nuclear Proteins - immunology | Protein Binding - immunology | Reverse Transcriptase Polymerase Chain Reaction | Proto-Oncogene Proteins c-myc - metabolism | Chromatin Assembly and Disassembly - immunology | Mice, Knockout | Transcription Factors - metabolism | Cell Differentiation - immunology | DNA Helicases - metabolism | Animals | B-Lymphocytes - immunology | Immunoglobulin Heavy Chains - metabolism | Enhancer Elements, Genetic - genetics | Proto-Oncogene Proteins c-myc - genetics | Immunoglobulin Heavy Chains - genetics | Cell Lineage - immunology | Chromatin | Cellular control mechanisms | Genetic research | Genetic aspects | B cells | Genetic transcription | Research | Properties
Journal Article