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Journal Article
Nature Immunology, ISSN 1529-2908, 03/2014, Volume 15, Issue 3, pp. 283 - 293
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 1761, Volume 289, Issue 18, pp. 12446 - 12456
Background: miRNA is a key component of post-transcriptional network governing the fate of T cells. Results: By targeting PTEN and IKZF4, miR-17-92 cluster... 
Autoimmunity | BIOCHEMISTRY & MOLECULAR BIOLOGY | HELPER-CELLS | Inflammation | Pten | IKZF4 | MicroRNA | T Cell | ROR-GAMMA | MIR-17-SIMILAR-TO-92 FAMILY | REGULATORY T-CELLS | Cell Differentiation | miR-17-92 | DIFFERENTIATION | IMMUNE FUNCTION | Th17 | EXPRESSION | TH17 CELLS | LYMPHOCYTES | Multigene Family | Encephalomyelitis, Autoimmune, Experimental - metabolism | Colitis - genetics | Encephalomyelitis, Autoimmune, Experimental - immunology | MicroRNAs - metabolism | Ikaros Transcription Factor - genetics | Cell Differentiation - genetics | Inflammation - metabolism | Flow Cytometry | PTEN Phosphohydrolase - immunology | Th17 Cells - metabolism | Encephalomyelitis, Autoimmune, Experimental - genetics | Ikaros Transcription Factor - metabolism | Colitis - immunology | Carrier Proteins - immunology | Disease Models, Animal | Multiple Sclerosis - metabolism | PTEN Phosphohydrolase - genetics | Nerve Tissue Proteins - immunology | Gene Expression Regulation - immunology | Mice, Inbred C57BL | Cells, Cultured | PTEN Phosphohydrolase - metabolism | Multiple Sclerosis - genetics | Inflammation - immunology | MicroRNAs - immunology | Reverse Transcriptase Polymerase Chain Reaction | Nerve Tissue Proteins - genetics | Blotting, Western | Mice, Knockout | Nerve Tissue Proteins - metabolism | Carrier Proteins - genetics | Cell Differentiation - immunology | Animals | Carrier Proteins - metabolism | Ikaros Transcription Factor - immunology | Colitis - metabolism | Inflammation - genetics | Multiple Sclerosis - immunology | Th17 Cells - immunology | Mice | MicroRNAs - genetics | Immunology
Journal Article
Journal Article
Journal Article
Journal of Immunology, ISSN 0022-1767, 07/2015, Volume 195, Issue 1, pp. 145 - 155
Journal Article
Nature Immunology, ISSN 1529-2908, 07/2015, Volume 16, Issue 7, pp. 775 - 784
Early B cell development is orchestrated by the combined activities of the transcriptional regulators E2A, EBF1, Foxo1 and Ikaros. However, how the genome-wide... 
TRANSCRIPTION FACTORS | GENOMIC INTERACTIONS | HEMATOPOIETIC PROGENITOR CELLS | LEUKEMIA MAINTENANCE | IKAROS | DNA-BINDING PROTEINS | GENE-EXPRESSION | C-MYC | IMMUNOLOGY | REGULATORY ELEMENTS | LOCUS | Cell Proliferation | Precursor Cells, B-Lymphoid - metabolism | Chromatin Assembly and Disassembly - genetics | Precursor Cells, B-Lymphoid - immunology | DNA Helicases - immunology | Cell Differentiation - genetics | Flow Cytometry | Nuclear Proteins - genetics | Transcription Factors - immunology | DNA Helicases - genetics | Immunoglobulin Heavy Chains - immunology | B-Lymphocytes - metabolism | Cell Lineage - genetics | RNA Interference - immunology | Gene Expression Regulation - genetics | Gene Expression Regulation - immunology | Cells, Cultured | Proto-Oncogene Proteins c-myc - immunology | In Situ Hybridization, Fluorescence | Mice, Transgenic | Nuclear Proteins - metabolism | Transcription Factors - genetics | Enhancer Elements, Genetic - immunology | Nuclear Proteins - immunology | Protein Binding - immunology | Reverse Transcriptase Polymerase Chain Reaction | Proto-Oncogene Proteins c-myc - metabolism | Chromatin Assembly and Disassembly - immunology | Mice, Knockout | Transcription Factors - metabolism | Cell Differentiation - immunology | DNA Helicases - metabolism | Animals | B-Lymphocytes - immunology | Immunoglobulin Heavy Chains - metabolism | Enhancer Elements, Genetic - genetics | Proto-Oncogene Proteins c-myc - genetics | Immunoglobulin Heavy Chains - genetics | Cell Lineage - immunology | Chromatin | Cellular control mechanisms | Genetic research | Genetic aspects | B cells | Genetic transcription | Research | Properties
Journal Article
Blood, ISSN 0006-4971, 12/2006, Volume 108, Issue 13, pp. 4025 - 4034
Plasmacytoid dendritic cells (pDCs) are specialized DCs that produce high levels of type I IFN upon viral infection. Despite their key immunoregulatory role,... 
SYSTEMIC-LUPUS-ERYTHEMATOSUS | STRANDED-RNA | MUTANT MICE | INHIBITORY NK RECEPTOR | IN-VIVO | BONE-MARROW | INTERFERON-PRODUCING CELLS | HEMATOLOGY | TRANSCRIPTION FACTOR | CENTROMERIC HETEROCHROMATIN | LYMPHOID LINEAGE | Toxoplasma - immunology | fms-Like Tyrosine Kinase 3 - biosynthesis | Antigens, Protozoan - immunology | Dendritic Cells - immunology | Membrane Glycoproteins - biosynthesis | Toll-Like Receptor 9 - biosynthesis | Ikaros Transcription Factor - biosynthesis | fms-Like Tyrosine Kinase 3 - immunology | Interferon Type I - immunology | Ikaros Transcription Factor - genetics | Toll-Like Receptor 9 - immunology | Cell Differentiation - genetics | Interferon Type I - biosynthesis | Mice, Mutant Strains | Bone Marrow Cells - immunology | Toll-Like Receptor 7 - immunology | Herpesviridae Infections - genetics | Membrane Glycoproteins - immunology | Toll-Like Receptor 7 - biosynthesis | Gene Expression Regulation - genetics | Gene Expression Regulation - immunology | Muromegalovirus - immunology | Cell Differentiation - immunology | Animals | Ikaros Transcription Factor - immunology | Mice | Muromegalovirus - genetics | Bone Marrow Cells - metabolism | Herpesviridae Infections - immunology | Plasma Cells - immunology | Dendritic Cells | fms-Like Tyrosine Kinase 3 | Gene Expression Regulation | Muromegalovirus | Toll-Like Receptor 9 | Ikaros Transcription Factor | Toll-Like Receptor 7 | Interferon Type I | Antigens, Protozoan | Toxoplasma | Life Sciences | Herpesviridae Infections | Bone Marrow Cells | Immunology | Cell Differentiation | Plasma Cells | Membrane Glycoproteins | Hematopoiesis
Journal Article