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Analytical Chemistry, ISSN 0003-2700, 12/2018, Volume 90, Issue 24, pp. 14287 - 14293
Journal Article
Journal Article
Nature Immunology, ISSN 1529-2908, 2017, Volume 18, Issue 6, pp. 694 - 704
The transcription factor STAT5 has a critical role in B cell acute lymphoblastic leukemia (B-ALL). How STAT5 mediates this effect is unclear. Here we found... 
MAINTENANCE | ACTIVATION | PROTEIN | DISRUPTION | SUPER-ENHANCERS | IKAROS | ACUTE LYMPHOBLASTIC-LEUKEMIA | RECEPTOR | IMMUNOLOGY | NF-KAPPA-B | EXPRESSION | Prognosis | Humans | Gene Expression Regulation, Neoplastic | Protein Kinase C beta - genetics | B-Lymphocytes | Precursor Cell Lymphoblastic Leukemia-Lymphoma - mortality | NF-kappa B p50 Subunit - genetics | Ikaros Transcription Factor - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - metabolism | STAT5 Transcription Factor - metabolism | Protein-Tyrosine Kinases - genetics | Flow Cytometry | Chromatin Immunoprecipitation | Trans-Activators - genetics | Pre-B Cell Receptors - genetics | Real-Time Polymerase Chain Reaction | Signal Transduction | PAX5 Transcription Factor - genetics | Interferon Regulatory Factors - genetics | Proto-Oncogene Proteins - genetics | Survival Rate | Multiplex Polymerase Chain Reaction | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Animals | Adaptor Proteins, Signal Transducing - genetics | Mice | Care and treatment | Immune response | Development and progression | STAT5 | Genetic aspects | Acute lymphocytic leukemia | Health aspects | Protein kinase C | Transcription factors | Ikaros protein | Acute lymphatic leukemia | Cell survival | Leukemia | Gene regulation | T cell receptors | Stat5 protein | Lymphatic leukemia | B-cell receptor | Gene expression | Pax5 protein | Bruton's tyrosine kinase | Defects | Enhancers | PU.1 protein | BLNK protein | Lymphocytes B | Interferon regulatory factor 4 | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 05/2008, Volume 453, Issue 7191, pp. 110 - 114
Journal Article
Immunity, ISSN 1074-7613, 05/2012, Volume 36, Issue 5, pp. 717 - 730
Regulatory T (Treg) cells, driven by the Foxp3 transcription factor, are responsible for limiting autoimmunity and chronic inflammation. We showed that a... 
TARGET GENES | HOMEOSTASIS | AUTOIMMUNITY | INFLAMMATION | IN-VIVO | GENERATION | HISTONE-DEACETYLASE INHIBITORS | IMMUNOLOGY | INDEPENDENT REGULATION | RECEPTORS | EXPRESSION | Forkhead Transcription Factors - immunology | T-Lymphocytes, Regulatory - metabolism | Epigenesis, Genetic | Autoimmunity - genetics | Diabetes Mellitus, Type 1 - metabolism | Histone Acetyltransferases - genetics | Histone Deacetylases - immunology | T-Lymphocytes, Regulatory - immunology | Interleukin-2 - immunology | Autoimmunity - immunology | Forkhead Transcription Factors - metabolism | Histone Acetyltransferases - metabolism | Trans-Activators - genetics | Acetylation | Diabetes Mellitus, Type 1 - immunology | Lysine Acetyltransferase 5 | Transcription Factors - immunology | Carrier Proteins - immunology | Trans-Activators - immunology | Interleukin-2 - metabolism | Transforming Growth Factor beta - immunology | Promoter Regions, Genetic | Histone Deacetylases - genetics | Nerve Tissue Proteins - immunology | Mice, Inbred C57BL | Diabetes Mellitus, Type 1 - genetics | Histone Deacetylases - metabolism | Transcription Factors - genetics | Forkhead Transcription Factors - genetics | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Transcription Factors - metabolism | Carrier Proteins - genetics | Interleukin-2 - genetics | Animals | Carrier Proteins - metabolism | Transforming Growth Factor beta - genetics | Histone Acetyltransferases - immunology | Mice, Inbred NOD | Trans-Activators - metabolism | Mice | Transforming Growth Factor beta - metabolism | Autoimmunity | Oncology, Experimental | Genes | Histones | Research | DNA binding proteins | Diabetes | Transforming growth factors | T cells | Cancer | Transcription factors | Statistical analysis | Rodents | DNA methylation | Epigenetics | T cell receptors | Gene expression | Age | Index Medicus | Histone deacetylase | Ikaros protein | Immunoregulation | Diabetes mellitus | Inflammation | Lymphocytes T | Histone acetyltransferase | Promoters | epigenetics | Gene silencing | Interleukin 2 | Development | Foxp3 protein | Zinc finger proteins | Autoimmune diseases | Fusion protein
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 5, pp. e20475 - e20475
It has long been accepted that immunoglobulins (Igs) were produced by B lymphoid cells only. Recently Igs have been found to be expressed in various human... 
B-CELLS | REARRANGEMENT | LYMPHOCYTE DEVELOPMENT | MULTIDISCIPLINARY SCIENCES | V(D)J RECOMBINATION | CARCINOMAS | NONLYMPHOID CELLS | PROTEINS | ALPHA HEAVY-CHAIN | IMMUNOGLOBULIN-G | RAG-2 PROMOTER | Homeodomain Proteins - metabolism | Humans | NF-kappa B - metabolism | DNA-Binding Proteins - metabolism | Ikaros Transcription Factor - genetics | Basic Helix-Loop-Helix Transcription Factors - metabolism | Chromatin Immunoprecipitation | RNA Interference | Forkhead Transcription Factors - metabolism | Recombination, Genetic - genetics | Ikaros Transcription Factor - metabolism | Nuclear Proteins - genetics | Gene Expression Regulation, Neoplastic - physiology | Gene Expression Regulation, Neoplastic - genetics | Repressor Proteins - metabolism | Basic Helix-Loop-Helix Transcription Factors - genetics | Electrophoresis, Polyacrylamide Gel | Repressor Proteins - genetics | Nuclear Proteins - metabolism | DNA-Binding Proteins - genetics | Forkhead Transcription Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Homeodomain Proteins - genetics | NF-kappa B - genetics | Fluorescent Antibody Technique | Cell Line, Tumor | Forkhead Box Protein O1 | Enzymes | RNA | Analysis | Genes | Cancer cells | Genetic aspects | B cells | DNA binding proteins | Gene expression | Cancer | Chromatin | Transcription factors | Recombination | Immunoprecipitation | Colorectal cancer | Nuclei | Foxp1 protein | Proteins | Cell activation | FOXO1 protein | Lymphocytes | Acetylation | Deoxyribonucleic acid--DNA | Immunoglobulins | Lymphoid cells | RNA-mediated interference | RNA polymerase | Tumor cell lines | Polymerase chain reaction | Pathology | Overexpression | RAG2 protein | Ribonucleic acids | Lymphocytes B | RAG1 protein | Gene rearrangement | Cell lines | Regulatory mechanisms (biology) | Nuclei (cytology) | Immunofluorescence | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Molekuliarnaia biologiia, ISSN 0026-8984, 05/2017, Volume 51, Issue 3, p. 490
Journal Article
The Journal of Immunology, ISSN 0022-1767, 07/2002, Volume 169, Issue 1, pp. 261 - 270
The early B cell factor (EBF) is a transcription factor shown crucial for the development of B lymphocytes. The protein is expressed from the earliest stages... 
E2A PROTEINS | IKAROS GENE | LOOP-HELIX PROTEINS | TARGET GENES | HEAVY-CHAIN | LYMPHOCYTE DEVELOPMENT | DNA-BINDING PROTEINS | IMMUNOGLOBULIN ENHANCER | IMMUNOLOGY | MOUSE BONE-MARROW | TRANSCRIPTIONAL REGULATION | Protein Binding - genetics | Humans | Molecular Sequence Data | 5' Untranslated Regions - genetics | Helix-Loop-Helix Motifs - immunology | Trans-Activators - chemistry | E-Box Elements - immunology | 5' Untranslated Regions - immunology | Organ Specificity - immunology | Trans-Activators - physiology | Organ Specificity - genetics | Base Sequence | Cloning, Molecular | Trans-Activators - genetics | TCF Transcription Factors | Trans-Activators - biosynthesis | Nuclear Proteins - genetics | B-Lymphocytes - metabolism | Amino Acid Sequence | DNA-Binding Proteins - physiology | Transcription Factors - physiology | Mice, Inbred C57BL | Cells, Cultured | Transcription Factor 7-Like 1 Protein | Exons - genetics | Nuclear Proteins - metabolism | DNA-Binding Proteins - genetics | E-Box Elements - genetics | Protein Binding - immunology | DNA-Binding Proteins - chemistry | Helix-Loop-Helix Motifs - genetics | Animals | B-Lymphocytes - immunology | Base Composition | Mice | Mice, Inbred BALB C | Nuclear Proteins - physiology | HeLa Cells | Promoter Regions, Genetic - immunology | DNA-Binding Proteins - biosynthesis | Exons - immunology | Index Medicus | Abridged Index Medicus | Support | Medical and Health Sciences | Trans-Activators : genetics | Nuclear Proteins : genetics | Organ Specificity : immunology | Cultured | Nuclear Proteins : physiology | Organ Specificity : genetics | Human | Basic Medicine | Trans-Activators : biosynthesis | Trans-Activators : physiology | Transcription Factors : physiology | DNA-Binding Proteins : physiology | B-Lymphocytes : metabolism | Animal | 5' Untranslated Regions : immunology | Non-U.S. Gov't | Hela Cells | Exons : genetics | Inbred BALB C | DNA-Binding Proteins : chemistry | DNA-Binding Proteins : genetics | E-Box Elements : immunology | Medicin och hälsovetenskap | Protein Binding : immunology | Immunologi inom det medicinska området | Helix-Loop-Helix Motifs : immunology | Molecular | Trans-Activators : chemistry | Exons : immunology | DNA-Binding Proteins : biosynthesis | Helix-Loop-Helix Motifs : genetics | Protein Binding : genetics | E-Box Elements : genetics | Immunology in the medical area | B-Lymphocytes : immunology | Nuclear Proteins : metabolism | Cloning | Promoter Regions (Genetics) : immunology | Cells | Inbred C57BL | 5' Untranslated Regions : genetics | Medicinska och farmaceutiska grundvetenskaper
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2016, Volume 11, Issue 6, pp. e0157767 - e0157767
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 08/2012, Volume 40, Issue 15, pp. 7303 - 7318
Journal Article
Leukemia, ISSN 0887-6924, 08/2017, Volume 31, Issue 8, pp. 1760 - 1769
Journal Article