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Journal of Medicinal Chemistry, ISSN 0022-2623, 12/2016, Volume 59, Issue 23, pp. 10800 - 10806
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 03/2012, Volume 158, Issue 3, pp. 470 - 478
Journal Article
The Journal of Clinical Pharmacology, ISSN 0091-2700, 05/2018, Volume 58, Issue 5, pp. 666 - 673
Elbasvir (EBR)/grazoprevir (GZR) may be coadministered with immunosuppressant drugs in posttransplant people who are infected with hepatitis C virus. The aim... 
cyclosporine | drug‐drug interactions | tacrolimus | pharmacokinetics | grazoprevir | mycophenolate mofetil | prednisone | elbasvir | drug-drug interactions | EFFICACY | GRAZOPREVIR MK-5172 | SAFETY | COMBINATION THERAPY | LABEL PHASE-2 TRIAL | RIBAVIRIN | HEPATITIS-C VIRUS | GENOTYPE 1 INFECTION | PHARMACOLOGY & PHARMACY | ELBASVIR MK-8742 | TREATMENT-NAIVE PATIENTS | Quinoxalines - adverse effects | Antiviral Agents - pharmacokinetics | Area Under Curve | Humans | Immunosuppressive Agents - pharmacokinetics | Middle Aged | Imidazoles - administration & dosage | Benzofurans - administration & dosage | Male | Imidazoles - pharmacokinetics | Benzofurans - pharmacokinetics | Young Adult | Drug Interactions | Cyclosporine - pharmacokinetics | Adult | Female | Mycophenolic Acid - administration & dosage | Immunosuppressive Agents - administration & dosage | Tacrolimus - administration & dosage | Prednisone - administration & dosage | Quinoxalines - pharmacokinetics | Prednisone - adverse effects | Quinoxalines - administration & dosage | Administration, Oral | Imidazoles - adverse effects | Mycophenolic Acid - pharmacokinetics | Tacrolimus - pharmacokinetics | Tacrolimus - adverse effects | Antiviral Agents - administration & dosage | Benzofurans - adverse effects | Mycophenolic Acid - adverse effects | Antiviral Agents - adverse effects | Cyclosporine - adverse effects | Cyclosporine - administration & dosage | Prednisone - pharmacokinetics | Immunosuppressive Agents - adverse effects | Drug Combinations | Drugs | Mycophenolic acid | Cyclosporins | Transaminase | Viruses | Prednisone | Pharmacology | Hepatitis | Tacrolimus | Mycophenolate mofetil | Hepatitis C virus | Pharmacokinetics | Hepatitis C | Drug dosages | Prednisolone | Index Medicus
Journal Article
Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 3/2018, Volume 81, Issue 3, pp. 455 - 460
The purpose of this report is to describe, for the first time, the pharmacokinetics of dacarbazine (DTIC) and its metabolites... 
Pregnancy | Dacarbazine | Medicine & Public Health | Metabolites | Oncology | Cancer Research | Pharmacology/Toxicology | Pharmacokinetics | TRIMESTER | CANCER | METABOLITE 5-AMINOIMIDAZOLE-4-CARBOXAMIDE | WOMEN | PLASMA | 24-HOUR CREATININE CLEARANCE | ONCOLOGY | POSTPARTUM | CYP1A2 | NON-HODGKINS-LYMPHOMA | PHARMACOLOGY & PHARMACY | Dacarbazine - adverse effects | Area Under Curve | Hodgkin Disease - pathology | Humans | Antineoplastic Agents, Alkylating - administration & dosage | Drug Monitoring - methods | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Dacarbazine - pharmacology | Dacarbazine - analogs & derivatives | Antineoplastic Agents, Alkylating - blood | Hodgkin Disease - drug therapy | Pregnancy Complications, Neoplastic - drug therapy | Adult | Dacarbazine - pharmacokinetics | Female | Infant, Newborn | Dacarbazine - administration & dosage | Treatment Outcome | Antineoplastic Agents, Alkylating - pharmacokinetics | Pregnancy Complications, Neoplastic - pathology | Administration, Intravenous | Dacarbazine - blood | Bleomycin - pharmacology | Vinblastine - pharmacology | Antineoplastic Agents, Alkylating - adverse effects | Neoplasm Staging | Doxorubicin - pharmacology | Pregnancy Outcome | Anthracyclines | Lymphomas | Pregnant women | Vinblastine | Cytochrome P450 | Case reports | Pharmacology | Liquid chromatography | Gestation | CYP1A2 protein | Metabolism | High-performance liquid chromatography | Doxorubicin | Lymphoma | Postpartum | Bleomycin | Imidazole | Drug metabolism | Remission | Index Medicus
Journal Article
Journal Article
JAIDS Journal of Acquired Immune Deficiency Syndromes, ISSN 1525-4135, 06/2011, Volume 57, Issue 2, pp. 118 - 125
Journal Article
Annals of oncology : official journal of the European Society for Medical Oncology, ISSN 0923-7534, 07/2017, Volume 28, Issue 7, pp. 1631 - 1639
Background: Previous analysis of COMBI-d (NCT01584648) demonstrated improved progression-free survival (PFS) and overall survival (OS) with combination... 
trametinib | melanoma | durable outcomes | BRAF | metastatic | dabrafenib | MULTICENTER | OPEN-LABEL | COMBINATION | TRIAL | MEK INHIBITION | ONCOLOGY | DOUBLE-BLIND | POOLED ANALYSIS | NIVOLUMAB | IPILIMUMAB | VEMURAFENIB | Skin Neoplasms - drug therapy | Oximes - pharmacokinetics | Oximes - adverse effects | Humans | Antineoplastic Combined Chemotherapy Protocols - pharmacokinetics | Oximes - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Imidazoles - administration & dosage | Imidazoles - pharmacokinetics | Protein Kinase Inhibitors - adverse effects | Pyridones - administration & dosage | Time Factors | Melanoma - genetics | Skin Neoplasms - mortality | Protein Kinase Inhibitors - pharmacokinetics | Skin Neoplasms - pathology | Double-Blind Method | Drug Administration Schedule | Pyridones - pharmacokinetics | Imidazoles - adverse effects | Pyrimidinones - adverse effects | Risk Factors | Kaplan-Meier Estimate | Treatment Outcome | Disease Progression | Melanoma - secondary | Disease-Free Survival | Protein Kinase Inhibitors - administration & dosage | Pyrimidinones - pharmacokinetics | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Skin Neoplasms - genetics | Biomarkers, Tumor - genetics | Pyrimidinones - administration & dosage | Mutation | Pyridones - adverse effects | Melanoma - mortality | Index Medicus | Original
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 06/2015, Volume 58, Issue 11, pp. 4749 - 4770
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 12/2015, Volume 59, Issue 12, pp. 7903 - 7905
Journal Article
Journal Article
Xenobiotica, ISSN 0049-8254, 10/2013, Volume 43, Issue 10, pp. 920 - 931
Journal Article