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1. Full Text MicroRNAs Cooperatively Inhibit a Network of Tumor Suppressor Genes to Promote Pancreatic Tumor Growth and Progression
by Frampton, Adam E and Castellano, Leandro and Colombo, Teresa and Giovannetti, Elisa and Krell, Jonathan and Jacob, Jimmy and Pellegrino, Loredana and Roca-Alonso, Laura and Funel, Niccola and Gall, Tamara M.H and De Giorgio, Alexander and Pinho, Filipa G and Fulci, Valerio and Britton, David J and Ahmad, Raida and Habib, Nagy A and Coombes, R. Charles and Harding, Victoria and Knösel, Thomas and Stebbing, Justin and Jiao, Long R
Gastroenterology, ISSN 0016-5085, 2014, Volume 146, Issue 1, pp. 268 - 277.e18
Background & Aims There has not been a broad analysis of the combined effects of altered activities of microRNAs (miRNAs) in pancreatic ductal adenocarcinoma... 
Gastroenterology and Hepatology | miRNA−mRNA Interaction | Tumorigenesis | Pancreatic Cancer | Oncogene | miRNA-mRNA Interaction | SURVIVAL | TRANSFORMATION | POSTTRANSCRIPTIONAL REGULATION | CANCER CELLS | DUCTAL ADENOCARCINOMA | NEDD4L | IN-VITRO | TARGETS | GASTROENTEROLOGY & HEPATOLOGY | EXPRESSION | LASER MICRODISSECTION | Cell Proliferation | Prognosis | Tumor Suppressor Proteins - antagonists & inhibitors | Humans | Ubiquitin-Protein Ligases - antagonists & inhibitors | Gene Expression Profiling | Ubiquitin-Protein Ligases - physiology | Carcinoma, Pancreatic Ductal - genetics | Endosomal Sorting Complexes Required for Transport - antagonists & inhibitors | Genes, Tumor Suppressor - physiology | Nedd4 Ubiquitin Protein Ligases | Gene Expression Regulation, Neoplastic - genetics | RNA-Binding Proteins - antagonists & inhibitors | Immediate-Early Proteins - physiology | RNA-Binding Proteins - physiology | RNA, Messenger - genetics | Pancreatic Neoplasms - genetics | Disease Progression | Tumor Suppressor Proteins - physiology | Animals | Apoptosis Regulatory Proteins - antagonists & inhibitors | Cell Line, Tumor | Apoptosis Regulatory Proteins - physiology | Mice | MicroRNAs - genetics | MicroRNAs - physiology | Endosomal Sorting Complexes Required for Transport - physiology | Immediate-Early Proteins - antagonists & inhibitors | Care and treatment | MicroRNA | Pancreatic cancer | Analysis | Genes | Development and progression | Cancer | Index Medicus | Abridged Index Medicus
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2. Full Text PML Contributes to a Cellular Mechanism of Repression of Herpes Simplex Virus Type 1 Infection That Is Inactivated by ICP0
by Roger D. Everett and Sabine Rechter and Peer Papior and Nina Tavalai and Thomas Stamminger and Anne Orr
Journal of Virology, ISSN 0022-538X, 08/2006, Volume 80, Issue 16, pp. 7995 - 8005
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
PROMYELOCYTIC LEUKEMIA PROTEIN | ND10 | DOT-ASSOCIATED PROTEINS | DISRUPTION | VIROLOGY | EARLY GENE-EXPRESSION | HOST-CELL | SP100 PROTEINS | REGULATORY PROTEIN | NUCLEAR DOMAIN 10 | IMMEDIATE-EARLY PROTEINS | RNA, Small Interfering - genetics | Autoantigens - metabolism | Nuclear Proteins - analysis | Tumor Suppressor Proteins - antagonists & inhibitors | Antigens, Nuclear - metabolism | Humans | Neoplasm Proteins - physiology | Neoplasm Proteins - antagonists & inhibitors | Immediate-Early Proteins - metabolism | Tumor Suppressor Proteins - genetics | Ubiquitin-Protein Ligases - analysis | Antigens, Nuclear - analysis | Immediate-Early Proteins - analysis | Neoplasm Proteins - genetics | Nuclear Proteins - genetics | Fibroblasts - chemistry | Fibroblasts - metabolism | Autoantigens - analysis | Genome, Viral | Gene Expression | Transcription Factors - physiology | Herpesvirus 1, Human - metabolism | Ubiquitin-Protein Ligases - metabolism | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | Transcription Factors - genetics | Adaptor Proteins, Signal Transducing - analysis | Tumor Suppressor Proteins - physiology | Immediate-Early Proteins - genetics | Gene Expression Regulation, Viral | Nuclear Proteins - antagonists & inhibitors | Herpesvirus 1, Human - genetics | Nuclear Proteins - physiology | Adaptor Proteins, Signal Transducing - metabolism | Ubiquitin-Protein Ligases - genetics | Promyelocytic Leukemia Protein | Index Medicus | Virus-Cell Interactions
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3. Full Text Evidence for a Role of the Cellular ND10 Protein PML in Mediating Intrinsic Immunity against Human Cytomegalovirus Infections
by Nina Tavalai and Peer Papior and Sabine Rechter and Martina Leis and Thomas Stamminger
Journal of Virology, ISSN 0022-538X, 08/2006, Volume 80, Issue 16, pp. 8006 - 8018
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
SIMPLEX-VIRUS TYPE-1 | VIROLOGY | EARLY GENE-EXPRESSION | COVALENT MODIFICATION | NUCLEAR DOMAIN-10 ND10 | FLUORESCENT PROTEIN | CREB BINDING-PROTEIN | RETROVIRAL RESTRICTION | TRANSACTIVATOR PROTEIN | ACUTE PROMYELOCYTIC LEUKEMIA | DNA-REPLICATION | Autoantigens - metabolism | Nuclear Proteins - analysis | Tumor Suppressor Proteins - antagonists & inhibitors | Antigens, Nuclear - metabolism | Virus Replication - genetics | Humans | Neoplasm Proteins - antagonists & inhibitors | Cytomegalovirus Infections - immunology | Cytomegalovirus Infections - metabolism | Neoplasm Proteins - metabolism | Viral Proteins - metabolism | Immediate-Early Proteins - metabolism | Cell Nucleus - metabolism | Tumor Suppressor Proteins - genetics | Cell Nucleus - virology | Trans-Activators - genetics | Antigens, Nuclear - analysis | Neoplasm Proteins - genetics | Nuclear Proteins - genetics | Cytomegalovirus - physiology | Fibroblasts - chemistry | Fibroblasts - metabolism | Autoantigens - analysis | Fibroblasts - virology | Tumor Suppressor Proteins - metabolism | Viral Proteins - genetics | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | Transcription Factors - genetics | Transcription Factors - metabolism | Adaptor Proteins, Signal Transducing - analysis | Immediate-Early Proteins - genetics | Gene Expression Regulation, Viral | Nuclear Proteins - antagonists & inhibitors | Trans-Activators - metabolism | Cell Nucleus - chemistry | Adaptor Proteins, Signal Transducing - metabolism | Promyelocytic Leukemia Protein | Index Medicus | Virus-Cell Interactions
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4. Full Text Role for the kinase SGK1 in stress, depression, and glucocorticoid effects on hippocampal neurogenesis
by Christoph Anacker and Annamaria Cattaneo and Ksenia Musaelyan and Patricia A. Zunszain and Mark Horowitz and Raffaella Molteni and Alessia Luoni and Francesca Calabrese and Katherine Tansey and Massimo Gennarelli and Sandrine Thuret and Jack Price and Rudolf Uher and Marco A. Riva and Carmine M. Pariante
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2013, Volume 110, Issue 21, pp. 8708 - 8713
Stress and glucocorticoid hormones regulate hippocampal neurogenesis, but the molecular mechanisms mediating these effects are poorly understood. Here we... 
Phosphorylation | Messenger RNA | Glucocorticoids | Antidepressants | Genetic variation | Rodents | Neurogenesis | Progenitor cells | Hippocampus | Depressive disorders | Neuroplasticity | Hypothalamus-pituitary-adrenal axis | Stem cells | PROGENITOR CELLS | hypothalamus-pituitary-adrenal axis | stem cells | BEHAVIOR | MULTIDISCIPLINARY SCIENCES | antidepressants | CELL-PROLIFERATION | MODEL | RECEPTOR ANTAGONIST | RESPONSES | DENTATE GYRUS | MODULATION | neuroplasticity | AXIS | Receptors, Glucocorticoid - antagonists & inhibitors | Depression - pathology | Humans | Middle Aged | Stress, Physiological | Hedgehog Proteins - metabolism | Hydrocortisone - metabolism | Male | Receptors, Glucocorticoid - metabolism | RNA, Messenger - metabolism | Immediate-Early Proteins - metabolism | Cell Nucleus - metabolism | Cell Nucleus - pathology | Glucocorticoids - metabolism | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Adult | Female | Hippocampus - enzymology | Protein-Serine-Threonine Kinases - metabolism | Nerve Tissue Proteins - antagonists & inhibitors | Rats | Hippocampus - pathology | Rats, Sprague-Dawley | Depression - enzymology | Nerve Tissue Proteins - metabolism | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Animals | Signal Transduction - drug effects | Active Transport, Cell Nucleus - drug effects | Benzoates - pharmacology | Mifepristone - pharmacology | Cell Line, Transformed | Immediate-Early Proteins - antagonists & inhibitors | Physiological aspects | Corticosteroids | Hippocampus (Brain) | Phosphotransferases | Depression, Mental | Brain | Molecules | Hormones | Mental depression | Gene expression | Stress | Index Medicus | Biological Sciences | hypothalamus–pituitary–adrenal axis
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5. Full Text Akt/protein kinase B signaling inhibitor-2, a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing Akt
by Yang, Lin and Dan, Han C and Sun, Mei and Liu, Qiyuan and Sun, Xia-Meng and Feldman, Richard I and Hamilton, Andrew D and Polokoff, Mark and Nicosia, Santo V and Herlyn, Meenhard and Sebti, Said M and Cheng, Jin Q
Cancer Research, ISSN 0008-5472, 07/2004, Volume 64, Issue 13, pp. 4394 - 4399
Accumulated studies have shown that activation of the Akt pathway plays a pivotal role in malignant transformation and chemoresistance by inducing cell... 
SURVIVAL | APOPTOSIS | ACTIVATION | TRICYCLIC NUCLEOSIDE PHOSPHATE | ONCOLOGY | PATHWAY | PHOSPHORYLATION | PROTEIN-KINASE | RESISTANCE | FARNESYLTRANSFERASE | TRICIRIBINE | NIH 3T3 Cells | Apoptosis - drug effects | Humans | Substrate Specificity | Pyridazines - pharmacology | Immediate-Early Proteins | Protein-Serine-Threonine Kinases - antagonists & inhibitors | JNK Mitogen-Activated Protein Kinases | Nucleosides - pharmacology | Female | Cyclic AMP-Dependent Protein Kinases - antagonists & inhibitors | p38 Mitogen-Activated Protein Kinases | Protein-Serine-Threonine Kinases - metabolism | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | Protein-Serine-Threonine Kinases - physiology | Enzyme Inhibitors - pharmacology | Protein Kinase C - antagonists & inhibitors | Cell Division - drug effects | Nuclear Proteins | Proto-Oncogene Proteins c-akt | Xenograft Model Antitumor Assays | Animals | MAP Kinase Signaling System - drug effects | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Signal Transduction - drug effects | Mice, Nude | Proto-Oncogene Proteins - physiology | Cell Line, Tumor | Signal Transduction - physiology | Mice | Index Medicus
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6. Full Text The Two Functions of Herpes Simplex Virus 1 ICP0, Inhibition of Silencing by the CoREST/REST/HDAC Complex and Degradation of PML, Are Executed in Tandem
by Haidong Gu and Bernard Roizman
Journal of Virology, ISSN 0022-538X, 01/2009, Volume 83, Issue 1, pp. 181 - 187
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
ND10 | VIROLOGY | PROMYELOCYTIC LEUKEMIA | HISTONE DEACETYLASES | INFECTED-CELL PROTEIN-0 | SP100 PROTEINS | GENE-EXPRESSION | IMMEDIATE-EARLY PROTEIN | TYPE-1 | CDNA COPY | PROTEASOME-DEPENDENT DEGRADATION | Tumor Suppressor Proteins - antagonists & inhibitors | Humans | Cercopithecus aethiops | Mutation, Missense | Repressor Proteins - antagonists & inhibitors | Immediate-Early Proteins - metabolism | Herpesvirus 1, Human - physiology | Vero Cells | Nerve Tissue Proteins - antagonists & inhibitors | Tumor Suppressor Proteins - metabolism | DNA-Binding Proteins - antagonists & inhibitors | Mutagenesis, Site-Directed | Mutant Proteins - genetics | Ubiquitin-Protein Ligases - metabolism | Mutant Proteins - metabolism | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | Transcription Factors - metabolism | Animals | Immediate-Early Proteins - genetics | Virus Replication | Nuclear Proteins - antagonists & inhibitors | Histone Deacetylase Inhibitors | HeLa Cells | Co-Repressor Proteins | Ubiquitin-Protein Ligases - genetics | Promyelocytic Leukemia Protein | Amino Acid Substitution | Index Medicus | Virus-Cell Interactions
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7. Full Text Macrophage migration inhibitory factor promotes innate immune responses by suppressing glucocorticoid-induced expression of mitogen-activated protein kinase phosphatase-1
by Roger, Thierry and Chanson, Anne-Laure and Knaup-Reymond, Marlies and Calandra, Thierry
European Journal of Immunology, ISSN 0014-2980, 12/2005, Volume 35, Issue 12, pp. 3405 - 3413
The pro-inflammatory cytokine macrophage migration inhibitory factor (MIF) acts as a physiological counter-regulator of the immuno-suppressive effects of... 
Macrophage migration inhibitory factor | Innate immunity | Mitogen-activated protein kinase phosphatase-1 | Glucocorticoids | Macrophages | mitogen-activated protein kinase phosphatase-1 | IMMEDIATE-EARLY GENE | MAP KINASE | FACTOR MIF | KAPPA-B-ALPHA | IMMUNOLOGY | TUMOR-NECROSIS-FACTOR | TLR4 GENE | SEPTIC SHOCK | STIMULATED MACROPHAGES | migration inhibitory factor macrophages | glucocorticoids | REGULATORY ROLE | PROINFLAMMATORY CYTOKINE BIOSYNTHESIS | innate immunity. macrophage | Dual Specificity Phosphatase 1 | Humans | Cell Cycle Proteins - antagonists & inhibitors | Protein Tyrosine Phosphatases - antagonists & inhibitors | Protein Tyrosine Phosphatases - genetics | Phosphoprotein Phosphatases - biosynthesis | U937 Cells | Cell Cycle Proteins - genetics | Glucocorticoids - physiology | Protein Phosphatase 1 | Cell Line | Protein Tyrosine Phosphatases - biosynthesis | Immediate-Early Proteins - biosynthesis | Cell Cycle Proteins - biosynthesis | Phosphoprotein Phosphatases - antagonists & inhibitors | Immunity, Innate | Animals | Immediate-Early Proteins - genetics | Phosphoprotein Phosphatases - genetics | Glucocorticoids - antagonists & inhibitors | Macrophage Migration-Inhibitory Factors - physiology | Mice | Cytokines - antagonists & inhibitors | Cytokines - biosynthesis | Immediate-Early Proteins - antagonists & inhibitors | Index Medicus
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8. Full Text Oncogenic Ras differentially regulates metabolism and anoikis in extracellular matrix-detached cells
by Mason, J.A and Davison-Versagli, C.A and Leliaert, A.K and Pape, D.J and McCallister, C and Zuo, J and Durbin, S.M and Buchheit, C.L and Zhang, S and Schafer, Z.T
Cell Death and Differentiation, ISSN 1350-9047, 08/2016, Volume 23, Issue 8, pp. 1271 - 1282
In order for cancer cells to survive during metastasis, they must overcome anoikis, a caspase-dependent cell death process triggered by extracellular matrix... 
COLON-CANCER | SURVIVAL | BREAST-CANCER CELLS | APOPTOSIS | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROSTATE-CANCER | TUMOR-SUPPRESSOR | AKT | SERUM | PHLPP | CELL BIOLOGY | Caspase 7 - metabolism | ras Proteins - genetics | Humans | Phosphoprotein Phosphatases - metabolism | Caspase 3 - metabolism | Extracellular Matrix - metabolism | ras Proteins - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Immediate-Early Proteins - metabolism | RNA Interference | Adenosine Triphosphate - metabolism | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Benzamides - pharmacology | p38 Mitogen-Activated Protein Kinases - metabolism | Nuclear Proteins - genetics | Proto-Oncogene Proteins c-akt - metabolism | Protein-Serine-Threonine Kinases - metabolism | Hydrazines - pharmacology | HCT116 Cells | Protein-Serine-Threonine Kinases - genetics | ras Proteins - antagonists & inhibitors | Nuclear Proteins - metabolism | Phosphoprotein Phosphatases - antagonists & inhibitors | Down-Regulation - drug effects | Immediate-Early Proteins - genetics | Phosphoprotein Phosphatases - genetics | Signal Transduction - drug effects | Nuclear Proteins - antagonists & inhibitors | Cell Line, Tumor | Glucose - metabolism | Anoikis - drug effects | Immediate-Early Proteins - antagonists & inhibitors | RNA, Small Interfering - metabolism | Index Medicus | Original Paper
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9. Full Text CDK9 and SPT5 proteins are specifically required for expression of herpes simplex virus 1 replication-dependent late genes
by Zhao, Zhiyuan and Tang, Ka-Wei and Muylaert, Isabella and Samuelsson, Tore and Elias, Per and Sahlgrenska akademin and Göteborgs universitet and Gothenburg University and Institutionen för biomedicin, avdelningen för medicinsk kemi och cellbiologi and Institute of Biomedicine, Department of Medical Biochemistry and Cell Biology and Sahlgrenska Academy
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 37, pp. 15489 - 15500
DNA replication greatly enhances expression of the herpes simplex virus 1 (HSV-1) gamma 2 late genes by still unknown mechanisms. Here, we demonstrate that... 
RNA-POLYMERASE-II | MACROMOLECULAR-SYNTHESIS | TERMINAL DOMAIN | ELONGATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | GAMMA-2 GENES | TYPE-1 | PROMOTER | P-TEFB | ICP27 | Gene Expression Regulation, Viral - drug effects | Immunoprecipitation | Nucleic Acid Synthesis Inhibitors - pharmacology | DNA Replication - drug effects | Humans | Transcriptional Elongation Factors - chemistry | Transcriptional Elongation Factors - antagonists & inhibitors | Dichlororibofuranosylbenzimidazole - pharmacology | Promoter Regions, Genetic - drug effects | Viral Proteins - metabolism | Chromosomal Proteins, Non-Histone - antagonists & inhibitors | Immediate-Early Proteins - metabolism | Herpesvirus 1, Human - physiology | Chromatin Immunoprecipitation | RNA Interference | Herpesvirus 1, Human - growth & development | Immediate-Early Proteins - chemistry | Transcriptional Elongation Factors - genetics | Cell Line | Virus Replication - drug effects | Antiviral Agents - pharmacology | Chromosomal Proteins, Non-Histone - metabolism | Cyclin-Dependent Kinase 9 - genetics | Viral Proteins - chemistry | Computational Biology | Viral Proteins - genetics | Transcription Factors - antagonists & inhibitors | Viral Proteins - antagonists & inhibitors | Cyclin-Dependent Kinase 9 - antagonists & inhibitors | Transcription Factors - genetics | Chromosomal Proteins, Non-Histone - genetics | Herpesvirus 1, Human - drug effects | Transcription Factors - metabolism | Transcriptional Elongation Factors - metabolism | Immediate-Early Proteins - genetics | Cyclin-Dependent Kinase 9 - metabolism | Protein Kinase Inhibitors - pharmacology | Mutation | Chromosomal Proteins, Non-Histone - chemistry | Amino Acid Substitution | Index Medicus | viral replication | cyclin-dependent kinase (CDK) | Microbiology | herpesvirus | post-transcriptional regulation | gene expression | Biological Sciences | p-tefb | terminal domain | rna-polymerase-ii | type-1 late gene | cell | transcription elongation | macromolecular-synthesis | Biochemistry & Molecular Biology | p385 | 1984 | p253 | Biologiska vetenskaper | 1981 | knight sl | tata box | messenger-rna | v25 | thymidine kinase gene | infected-cells | v37
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10. Full Text Characterization of recombinant human cytomegaloviruses encoding IE1 mutants L174P and 1-382 reveals that viral targeting of PML bodies perturbs both intrinsic and innate immune responses
by Scherer, Myriam and Otto, Victoria and Stump, Joachim D and Klingl, Stefan and Müller, Regina and Reuter, Nina and Muller, Yves A and Sticht, Heinrich and Stamminger, Thomas
Journal of Virology, ISSN 0022-538X, 2016, Volume 90, Issue 3, pp. 1190 - 1205
PML is the organizer of cellular structures termed nuclear domain 10 (ND10) or PML-nuclear bodies (PML-NBs) that act as key mediators of intrinsic immunity... 
PROMYELOCYTIC-LEUKEMIA-PROTEIN | ANTIVIRAL DEFENSE | VIROLOGY | EARLY GENE-EXPRESSION | DOMAIN 10 | COVALENT MODIFICATION | ESCHERICHIA-COLI | SP100 PROTEINS | HERPESVIRUS-INFECTION | NUCLEAR-BODY FORMATION | EARLY TIMES | Cytomegalovirus - genetics | Sequence Deletion | Tumor Suppressor Proteins - metabolism | Tumor Suppressor Proteins - antagonists & inhibitors | Humans | Computational Biology | Mutant Proteins - genetics | Models, Molecular | Mutant Proteins - metabolism | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | Immunity, Innate | Host-Pathogen Interactions | Transcription Factors - metabolism | Cytomegalovirus - immunology | Immediate-Early Proteins - metabolism | Point Mutation | Immediate-Early Proteins - genetics | Nuclear Proteins - antagonists & inhibitors | Protein Conformation | Cytomegalovirus - physiology | Promyelocytic Leukemia Protein | Index Medicus
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11. Full Text Regulation of ICP0-Null Mutant Herpes Simplex Virus Type 1 Infection by ND10 Components ATRX and hDaxx
by Vera Lukashchuk and Roger D. Everett
Journal of Virology, ISSN 0022-538X, 04/2010, Volume 84, Issue 8, pp. 4026 - 4040
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
UBIQUITIN-SPECIFIC PROTEASE | LYTIC INFECTION | VIROLOGY | TRANSCRIPTION REPRESSOR DAXX | HISTONE DEACETYLASES | EARLY GENE-EXPRESSION | QUIESCENT VIRAL GENOMES | HUMAN CYTOMEGALOVIRUS | NUCLEAR DOMAIN 10 | MEDIATED REPRESSION | ACUTE PROMYELOCYTIC LEUKEMIA | Cell Line | Humans | Cells, Cultured | Viral Plaque Assay | Gene Expression Profiling | X-linked Nuclear Protein | DNA Helicases - immunology | Nuclear Proteins - immunology | Gene Knockdown Techniques | RNA Interference | Adaptor Proteins, Signal Transducing - antagonists & inhibitors | Herpesvirus 1, Human - growth & development | Nuclear Proteins - antagonists & inhibitors | Genes, Viral | Adaptor Proteins, Signal Transducing - immunology | Immediate-Early Proteins - deficiency | Ubiquitin-Protein Ligases - deficiency | Herpesvirus 1, Human - genetics | Herpesvirus 1, Human - immunology | DNA Helicases - antagonists & inhibitors | Index Medicus | Virus-Cell Interactions
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12. Full Text Development of a small-molecule serum- and glucocorticoid-regulated kinase-1 antagonist and its evaluation as a prostate cancer therapeutic
by Sherk, Andrea B and Frigo, Daniel E and Schnackenberg, Christine G and Bray, Jeffrey D and Laping, Nicholas J and Trizna, Walter and Hammond, Marlys and Patterson, Jaclyn R and Thompson, Scott K and Kazmin, Dmitri and Norris, John D and McDonnell, Donald P
Cancer Research, ISSN 0008-5472, 09/2008, Volume 68, Issue 18, pp. 7475 - 7483
Androgens, through their actions on the androgen receptor (AR), are required for the development of the prostate and contribute to the pathologic growth... 
PROMOTER ACTIVITY | ANDROGEN RECEPTOR | EPITHELIAL-CELLS | MESSENGER-RNA | ONCOLOGY | CELL-SURVIVAL RESPONSE | GENE-EXPRESSION | SERUM | RAT-BRAIN | INDUCIBLE PROTEIN-KINASE | BINDING POCKET | RNA, Small Interfering - genetics | Up-Regulation | Humans | Receptors, Androgen - metabolism | Cell Growth Processes - physiology | Male | Immediate-Early Proteins - metabolism | RNA, Messenger - biosynthesis | Prostatic Neoplasms - genetics | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Metribolone - pharmacology | Prostatic Neoplasms - drug therapy | Protein-Serine-Threonine Kinases - metabolism | Prostatic Neoplasms - pathology | Immediate-Early Proteins - biosynthesis | RNA, Messenger - genetics | Protein-Serine-Threonine Kinases - genetics | Protein-Serine-Threonine Kinases - biosynthesis | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Immediate-Early Proteins - genetics | Benzoates - pharmacology | Cell Line, Tumor | Prostatic Neoplasms - enzymology | Protein Kinase Inhibitors - pharmacology | HeLa Cells | Immediate-Early Proteins - antagonists & inhibitors | Index Medicus | prostate cancer | androgen receptor | serum and glucocorticoid-regulated kinase 1
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13. Full Text Roles of AUF1 isoforms, HuR and BRF1 in ARE-dependent mRNA turnover studied by RNA interference
by Raineri, Ines and Wegmueller, Daniel and Gross, Brigitte and Certa, Ulrich and Moroni, Christoph
Nucleic Acids Research, ISSN 0305-1048, 2004, Volume 32, Issue 4, pp. 1279 - 1288
HT1080 cells stably expressing green fluorescent protein (GFP) linked to a 3' terminal AU-rich element (ARE) proved to be a convenient system to study the... 
HNRNP D | RICH ELEMENT | COLONY-STIMULATING FACTOR | C-FOS | TRISTETRAPROLIN | DESTABILIZING ELEMENTS | STABILITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | DEGRADATION PATHWAY | ELEMENT-BINDING PROTEIN | TNF-ALPHA | ELAV-Like Protein 1 | RNA-Binding Proteins - genetics | Humans | Regulatory Sequences, Ribonucleic Acid | RNA, Messenger - metabolism | ELAV Proteins | Antigens, Surface - physiology | Butyrate Response Factor 1 | Heterogeneous-Nuclear Ribonucleoprotein D - antagonists & inhibitors | RNA Interference | RNA-Binding Proteins - antagonists & inhibitors | Cell Line | Heterogeneous-Nuclear Ribonucleoprotein D - genetics | DNA-Binding Proteins - physiology | DNA-Binding Proteins - antagonists & inhibitors | Heterogeneous-Nuclear Ribonucleoprotein D - physiology | Immediate-Early Proteins - physiology | RNA-Binding Proteins - physiology | RNA, Small Interfering - pharmacology | Antigens, Surface - genetics | DNA-Binding Proteins - genetics | RNA Stability | Protein Isoforms - physiology | Granulocyte-Macrophage Colony-Stimulating Factor - genetics | Immediate-Early Proteins - genetics | Immediate-Early Proteins - antagonists & inhibitors | Protein Isoforms - antagonists & inhibitors | Protein Isoforms - genetics | Index Medicus
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14. Full Text Human Cytomegalovirus pUL83 Stimulates Activity of the Viral Immediate-Early Promoter through Its Interaction with the Cellular IFI16 Protein
by Ileana M. Cristea and Nathaniel J. Moorman and Scott S. Terhune and Christian D. Cuevas and Erin S. O'Keefe and Michael P. Rout and Brian T. Chait and Thomas Shenk
Journal of Virology, ISSN 0022-538X, 08/2010, Volume 84, Issue 15, pp. 7803 - 7814
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
STRUCTURAL PROTEIN | TRANSCRIPTIONAL ACTIVATION | INTERFERON-INDUCIBLE PROTEIN | VIROLOGY | EARLY GENE-EXPRESSION | ENDOTHELIAL-CELLS | INFECTED-CELLS | TEGUMENT PROTEINS | NF-KAPPA-B | GLYCOPROTEIN-B | MOUSE CYTOMEGALOVIRUS | Fibroblasts - virology | Promoter Regions, Genetic | Viral Matrix Proteins - genetics | Humans | Transcriptional Activation | Cells, Cultured | DNA, Viral - metabolism | Nuclear Proteins - metabolism | Phosphoproteins - antagonists & inhibitors | Codon, Nonsense | Mutation, Missense | Phosphoproteins - genetics | Phosphoproteins - metabolism | Gene Knockdown Techniques | Protein Interaction Mapping | Host-Pathogen Interactions | Nuclear Proteins - antagonists & inhibitors | Protein Binding | Viral Matrix Proteins - metabolism | Genes, Immediate-Early | Cytomegalovirus - physiology | Genes, Reporter | Index Medicus | Virus-Cell Interactions
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15. Full Text Mitogen-activated protein kinase phosphatase-1 is a mediator of breast cancer chemoresistance
by Small, George W and Shi, Yue Y and Higgins, Linda S and Orlowski, Robert Z
Cancer Research, ISSN 0008-5472, 05/2007, Volume 67, Issue 9, pp. 4459 - 4466
The mitogen-activated protein kinase (MAPK) phosphatase (MKP)-1 is overexpressed in a large proportion of breast cancers, and in some systems interferes with... 
GENOTOXIC STRESS | EPITHELIAL-CELLS | ONCOLOGY | INDUCED APOPTOSIS | TRANSCRIPTIONAL INDUCTION | N-TERMINAL KINASE | CONDITIONAL EXPRESSION | P38 MAPK | C-JUN | MAPK PHOSPHATASE-1 | CELLULAR-RESPONSE | Dual Specificity Phosphatase 1 | Paclitaxel - pharmacology | Apoptosis - drug effects | Humans | Phosphoprotein Phosphatases - metabolism | Drug Resistance, Neoplasm | Protein Tyrosine Phosphatases - metabolism | Mechlorethamine - pharmacology | Cell Cycle Proteins - antagonists & inhibitors | Immediate-Early Proteins - metabolism | Protein Tyrosine Phosphatases - antagonists & inhibitors | Breast Neoplasms - enzymology | Protein Tyrosine Phosphatases - genetics | Drug Interactions | MAP Kinase Kinase 4 - metabolism | Cell Cycle Proteins - genetics | Indoles - pharmacology | p38 Mitogen-Activated Protein Kinases - metabolism | Protein Phosphatase 1 | Cell Cycle Proteins - metabolism | Phosphoprotein Phosphatases - antagonists & inhibitors | Enzyme Activation - drug effects | Breast Neoplasms - drug therapy | Immediate-Early Proteins - genetics | Phosphoprotein Phosphatases - genetics | Breast Neoplasms - pathology | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Cell Line, Tumor | Doxorubicin - pharmacology | Immediate-Early Proteins - antagonists & inhibitors | Index Medicus
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